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The map label for this gene is dnaA [H]

Identifier: 118475779

GI number: 118475779

Start: 351

End: 1748

Strand: Direct

Name: dnaA [H]

Synonym: BALH_0001

Alternate gene names: 118475779

Gene position: 351-1748 (Clockwise)

Preceding gene: NA

Following gene: 118475780

Centisome position: 0.01

GC content: 35.48

Gene sequence:

>1398_bases
TTGTACATTTGTTGCACAACCTTATTCTTTTACCATCTTAGTAAAGGAGGGACACCTTTGGAAAACATCTCTGATTTATG
GAACAGCGCCTTAAAAGAACTCGAAAAAAAGGTCAGTAAACCCAGTTATGAAACATGGTTAAAATCAACAACCGCACATA
ATTTAAAGAAAGATGTATTAACAATTACGGCTCCAAATGAATTCGCCCGTGATTGGTTAGAATCTCATTATTCAGAGCTA
ATTTCGGAAACACTTTATGATTTAACGGGGGCAAAATTAGCTATTCGCTTTATTATTCCCCAAAGTCAAGCTGAAGAGGA
GATTGATCTTCCTCCTGCTAAACCAAATGCAGCACAAGATGATTCTAATCATTTACCACAGAGTATGCTAAACCCAAAAT
ATACGTTTGATACATTTGTTATTGGCTCTGGTAACCGTTTTGCTCACGCTGCTTCATTAGCCGTAGCCGAAGCGCCAGCT
AAAGCATATAATCCCCTCTTTATTTATGGGGGAGTTGGACTTGGAAAAACCCATTTAATGCATGCAATTGGCCATTATGT
AATTGAACATAACCCAAATGCCAAAGTTGTATATTTATCATCAGAAAAATTTACAAATGAATTCATTAATTCTATTCGTG
ATAATAAAGCGGTCGATTTTCGTAATAAATACCGCAATGTAGATGTTTTATTGATAGATGATATTCAATTTTTAGCGGGA
AAAGAACAAACTCAAGAAGAGTTTTTCCATACATTCAATGCATTACACGAAGAAAGTAAACAAATTGTAATTTCCAGTGA
TCGGCCACCAAAAGAAATTCCAACTTTAGAAGATCGTCTTCGTTCTCGCTTTGAATGGGGACTCATTACGGATATTACGC
CACCAGATTTAGAAACACGAATTGCGATTTTACGTAAAAAGGCAAAGGCTGAAGGACTTGATATACCAAATGAGGTCATG
CTTTATATCGCAAATCAAATCGATTCAAATATTCGTGAACTAGAAGGTGCACTCATCCGCGTTGTAGCTTATTCATCTTT
AATTAACAAGGATATTAATGCTGATTTAGCAGCTGAAGCACTTAAAGATATTATTCCAAATTCTAAACCAAAAATTATCT
CCATTTATGATATTCAAAAAGCTGTTGGAGATGTTTATCAAGTAAAATTAGAAGATTTCAAGGCGAAAAAGCGCACAAAG
TCAGTTGCCTTTCCTCGCCAAATTGCAATGTATTTGTCACGCGAACTGACAGATTCCTCCTTACCTAAAATAGGTGAAGA
ATTTGGTGGACGTGATCATACAACCGTTATCCATGCCCATGAAAAAATTTCTAAGCTACTTAAGACGGATACGCAATTAC
AAAAACAAGTTGAAGAAATTAACGATATTTTAAAGTAG

Upstream 100 bases:

>100_bases
ACATTTGCTTTTTTTGTCGAAAACCCTATCTCATATACAAACGACGTTTTTAGGTTTTAAAATACGTTTCGTATAAATAT
ACATTTTATATTTATTCAGG

Downstream 100 bases:

>100_bases
TAGCTGAATAGTGTGAATAACTTTCCTTGTTTTACGCACAGTCTATCCACATGTAGATAGACTGTTTTTACATCTTTCAA
CGGGGTTATCCACATATCCA

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MYICCTTLFFYHLSKGGTPLENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVLTITAPNEFARDWLESHYSEL
ISETLYDLTGAKLAIRFIIPQSQAEEEIDLPPAKPNAAQDDSNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPA
KAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAG
KEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVM
LYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTK
SVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINDILK

Sequences:

>Translated_465_residues
MYICCTTLFFYHLSKGGTPLENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVLTITAPNEFARDWLESHYSEL
ISETLYDLTGAKLAIRFIIPQSQAEEEIDLPPAKPNAAQDDSNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPA
KAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAG
KEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVM
LYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTK
SVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINDILK
>Mature_465_residues
MYICCTTLFFYHLSKGGTPLENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVLTITAPNEFARDWLESHYSEL
ISETLYDLTGAKLAIRFIIPQSQAEEEIDLPPAKPNAAQDDSNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPA
KAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAG
KEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVM
LYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTK
SVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINDILK

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=445, Percent_Identity=44.4943820224719, Blast_Score=388, Evalue=1e-109,
Organism=Escherichia coli, GI226510964, Length=201, Percent_Identity=24.8756218905473, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 52642; Mature: 52642

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYICCTTLFFYHLSKGGTPLENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVL
CEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEE
TITAPNEFARDWLESHYSELISETLYDLTGAKLAIRFIIPQSQAEEEIDLPPAKPNAAQD
EEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCC
DSNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLM
CCCCCCHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCHHHCCCEEEECCCCCCHHHHH
HAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAG
HHHHHHHEEECCCEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHCCCEEEEECCHHHHHC
KEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETR
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCEECCCCCCCHHHH
IAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDSS
HHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
LPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINDILK
CHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYICCTTLFFYHLSKGGTPLENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVL
CEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEE
TITAPNEFARDWLESHYSELISETLYDLTGAKLAIRFIIPQSQAEEEIDLPPAKPNAAQD
EEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCC
DSNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLM
CCCCCCHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCHHHCCCEEEECCCCCCHHHHH
HAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAG
HHHHHHHEEECCCEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHCCCEEEEECCHHHHHC
KEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETR
CHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCEECCCCCCCHHHH
IAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDSS
HHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
LPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINDILK
CHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA