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The map label for this gene is dipZ [H]

Identifier: 117922012

GI number: 117922012

Start: 4289315

End: 4291156

Strand: Direct

Name: dipZ [H]

Synonym: Shewana3_3576

Alternate gene names: 117922012

Gene position: 4289315-4291156 (Clockwise)

Preceding gene: 117922011

Following gene: 117922013

Centisome position: 86.27

GC content: 50.38

Gene sequence:

>1842_bases
ATGAAAAAACTACTTAGCTTTATCTTCACCGCATTACTGCTGCTTGCGCCCTTAACTCAAAGTAGCAATGCCTTCGCCAA
TAGCTTCGGTTTTCTAAAAAGTGAGCCAGAGTTAATGCCTGTCGATCAAGCCTTTGCCTTCGATTTTAAGCAGGAAGGCA
ATAAGGTCACCCTCAATTGGGTCATTGCCGACGGCTACTATATGTATCGGGATAAGCTTAAGTTTAGTGTCAATGGCGCC
GAACTTGGCACCATAGATCTGCCAAAGGGCAAACCCCACAACGACGAATATTTCGGTGAGCAAGAGGTGTACTACACCTA
TATCGATATTCCCGTTGGCCTGAAACAAGCCGATGATAACGGCACCTTAACCGTGACCTTTATGGGCTGCGCCGAGGGTA
AACTCTGTTATCCACCGACCAAGCGCGATGTCACCCTAAAAGCTGTCGCGGCCAATGATGGCCAAATCGCGACTGGTACA
GACAGCAGCGAAAATTCTGAGTCTGCCGCCACTGCTGACGCTAAGCAAACTAGCAGCGTCCCAAGCCAACCTATTACCCA
GCAGGATAGCCTAAGCCAGATGCTGTCTAACGACAGTTTACTCTGGACCTTAGTGATCTTCTTCGGCCTAGGGATTGGTC
TGGCGCTCACGCCTTGCGTCTTCCCTATGTACCCGATCCTATCGGGCATTATTGTTGGCCAAGGGCAAAAACTCTCGACC
GCTAAGGCCTTTACCCTGTCGATGGCCTATGTGCAGGGTATGGCGATCACCTACTCGATTTTAGGTCTAGTGGTTGCCTC
TGCGGGGATGAAATATCAAGCGGCGCTGCAACATCCCGCCGTGCTGATCTTTTTAGCTATCCTGTTCTTTGTACTCAGTT
TATCCATGTTTGGCTTGTACGATCTCAAACTGCCTTCAAGCTGGCAGGAGAAGATGAACTCGATTTCAAACAATCAAAAG
GGCGGCAATTTAGTTGGCGTGTTTTTGATGGGGGTGATATCGGGATTAGTGGCCTCACCTTGTACAACGGCCCCACTTTC
AGGCGCCTTAGTCTATGTGGCGCAAACCGGTGATTTATTGCAAGGTTTCCTCGCGCTCTACGTGCTGAGCATGGGTATGG
GTGTGCCGCTACTTATCATTGGTACCTCGGGTGGTAAGTTACTGCCACGCGCTGGCGCTTGGATGAACATCATTAAAACC
GTGTTCGGTTTCCTCCTGATTGCCGTATCGATTGTGATGCTTGGCCGTATTTGGACGGGTGTGGTTTCCGATGTGCTCTG
GTCACTCTGGGGCATTAGCTTCACCGGTTACCTGATGCACCAAAACAAACTCAGCGCCTTCAACTGGAAACAAACCGTGC
GCTCAGTGCTGCTGACACTCACGCTGTTGGCCAGTTTCTCCTACGGTTTCCAAGCGGTCATGGGCCACTTTGGCTTTACC
CATGCGCCAATGGGCACTGTGGCGACAACCGAGCAGGAGCACGGCTTTAAACGGATTAAATCTATTGAAGATTTAGACCG
TGAAATCGCCGCCGCAACCGCTGCGGGTAAGCCTGTGATGCTGGATCTCTACGCCGATTGGTGTGTGGCCTGTAAAGAGT
TTGAGGCCATCACCTTTAAGGACGCCGAAGTGCTAGTGCGGATGAACAAGATAGTGTTATTACAGGCCGACGTGACTAAG
AGCGATGCCGTGGATGTGGCACTGCTAGAGAAATACAATGTGCTGGGCCTACCGACGCTGCTGATGTTTAACGAGCAAGG
TGAGCAGAGGGAAGATTTAAGAGTGACTGGCTTTATGGGACCGAAGGAATTTGCCGCCCATTTAGATCACTTAGTGAAAT
AA

Upstream 100 bases:

>100_bases
TGCTTCAACTCCACCCTTATCAAGTGCCTGAAATTATTGCCGTACCCGTCACTCACGGGCTACCAGCCTATTTAGATTGG
ATAAAAGATAACACTCAGCC

Downstream 100 bases:

>100_bases
TCTCAGCTAAAACGCCAATTTATCTCTGCGCCGTTTTAGCGTAAAACCAATAAAAAGCGGACTTTTTTCATTAAAAGTCC
GCTTTTTTATCACGCTGTCA

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MKKLLSFIFTALLLLAPLTQSSNAFANSFGFLKSEPELMPVDQAFAFDFKQEGNKVTLNWVIADGYYMYRDKLKFSVNGA
ELGTIDLPKGKPHNDEYFGEQEVYYTYIDIPVGLKQADDNGTLTVTFMGCAEGKLCYPPTKRDVTLKAVAANDGQIATGT
DSSENSESAATADAKQTSSVPSQPITQQDSLSQMLSNDSLLWTLVIFFGLGIGLALTPCVFPMYPILSGIIVGQGQKLST
AKAFTLSMAYVQGMAITYSILGLVVASAGMKYQAALQHPAVLIFLAILFFVLSLSMFGLYDLKLPSSWQEKMNSISNNQK
GGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLLQGFLALYVLSMGMGVPLLIIGTSGGKLLPRAGAWMNIIKT
VFGFLLIAVSIVMLGRIWTGVVSDVLWSLWGISFTGYLMHQNKLSAFNWKQTVRSVLLTLTLLASFSYGFQAVMGHFGFT
HAPMGTVATTEQEHGFKRIKSIEDLDREIAAATAAGKPVMLDLYADWCVACKEFEAITFKDAEVLVRMNKIVLLQADVTK
SDAVDVALLEKYNVLGLPTLLMFNEQGEQREDLRVTGFMGPKEFAAHLDHLVK

Sequences:

>Translated_613_residues
MKKLLSFIFTALLLLAPLTQSSNAFANSFGFLKSEPELMPVDQAFAFDFKQEGNKVTLNWVIADGYYMYRDKLKFSVNGA
ELGTIDLPKGKPHNDEYFGEQEVYYTYIDIPVGLKQADDNGTLTVTFMGCAEGKLCYPPTKRDVTLKAVAANDGQIATGT
DSSENSESAATADAKQTSSVPSQPITQQDSLSQMLSNDSLLWTLVIFFGLGIGLALTPCVFPMYPILSGIIVGQGQKLST
AKAFTLSMAYVQGMAITYSILGLVVASAGMKYQAALQHPAVLIFLAILFFVLSLSMFGLYDLKLPSSWQEKMNSISNNQK
GGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLLQGFLALYVLSMGMGVPLLIIGTSGGKLLPRAGAWMNIIKT
VFGFLLIAVSIVMLGRIWTGVVSDVLWSLWGISFTGYLMHQNKLSAFNWKQTVRSVLLTLTLLASFSYGFQAVMGHFGFT
HAPMGTVATTEQEHGFKRIKSIEDLDREIAAATAAGKPVMLDLYADWCVACKEFEAITFKDAEVLVRMNKIVLLQADVTK
SDAVDVALLEKYNVLGLPTLLMFNEQGEQREDLRVTGFMGPKEFAAHLDHLVK
>Mature_613_residues
MKKLLSFIFTALLLLAPLTQSSNAFANSFGFLKSEPELMPVDQAFAFDFKQEGNKVTLNWVIADGYYMYRDKLKFSVNGA
ELGTIDLPKGKPHNDEYFGEQEVYYTYIDIPVGLKQADDNGTLTVTFMGCAEGKLCYPPTKRDVTLKAVAANDGQIATGT
DSSENSESAATADAKQTSSVPSQPITQQDSLSQMLSNDSLLWTLVIFFGLGIGLALTPCVFPMYPILSGIIVGQGQKLST
AKAFTLSMAYVQGMAITYSILGLVVASAGMKYQAALQHPAVLIFLAILFFVLSLSMFGLYDLKLPSSWQEKMNSISNNQK
GGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLLQGFLALYVLSMGMGVPLLIIGTSGGKLLPRAGAWMNIIKT
VFGFLLIAVSIVMLGRIWTGVVSDVLWSLWGISFTGYLMHQNKLSAFNWKQTVRSVLLTLTLLASFSYGFQAVMGHFGFT
HAPMGTVATTEQEHGFKRIKSIEDLDREIAAATAAGKPVMLDLYADWCVACKEFEAITFKDAEVLVRMNKIVLLQADVTK
SDAVDVALLEKYNVLGLPTLLMFNEQGEQREDLRVTGFMGPKEFAAHLDHLVK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=601, Percent_Identity=45.4242928452579, Blast_Score=509, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 66621; Mature: 66621

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLSFIFTALLLLAPLTQSSNAFANSFGFLKSEPELMPVDQAFAFDFKQEGNKVTLNW
CHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEE
VIADGYYMYRDKLKFSVNGAELGTIDLPKGKPHNDEYFGEQEVYYTYIDIPVGLKQADDN
EEECCEEEEEEEEEEEECCCEECEEECCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCC
GTLTVTFMGCAEGKLCYPPTKRDVTLKAVAANDGQIATGTDSSENSESAATADAKQTSSV
CEEEEEEEECCCCCEECCCCCCCEEEEEEECCCCEEECCCCCCCCCCHHHCCCHHHHCCC
PSQPITQQDSLSQMLSNDSLLWTLVIFFGLGIGLALTPCVFPMYPILSGIIVGQGQKLST
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCH
AKAFTLSMAYVQGMAITYSILGLVVASAGMKYQAALQHPAVLIFLAILFFVLSLSMFGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCEE
DLKLPSSWQEKMNSISNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLL
EECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHH
QGFLALYVLSMGMGVPLLIIGTSGGKLLPRAGAWMNIIKTVFGFLLIAVSIVMLGRIWTG
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVSDVLWSLWGISFTGYLMHQNKLSAFNWKQTVRSVLLTLTLLASFSYGFQAVMGHFGFT
HHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HAPMGTVATTEQEHGFKRIKSIEDLDREIAAATAAGKPVMLDLYADWCVACKEFEAITFK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEEEEC
DAEVLVRMNKIVLLQADVTKSDAVDVALLEKYNVLGLPTLLMFNEQGEQREDLRVTGFMG
CHHHHEEECEEEEEEECCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEECCC
PKEFAAHLDHLVK
HHHHHHHHHHHCC
>Mature Secondary Structure
MKKLLSFIFTALLLLAPLTQSSNAFANSFGFLKSEPELMPVDQAFAFDFKQEGNKVTLNW
CHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEE
VIADGYYMYRDKLKFSVNGAELGTIDLPKGKPHNDEYFGEQEVYYTYIDIPVGLKQADDN
EEECCEEEEEEEEEEEECCCEECEEECCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCC
GTLTVTFMGCAEGKLCYPPTKRDVTLKAVAANDGQIATGTDSSENSESAATADAKQTSSV
CEEEEEEEECCCCCEECCCCCCCEEEEEEECCCCEEECCCCCCCCCCHHHCCCHHHHCCC
PSQPITQQDSLSQMLSNDSLLWTLVIFFGLGIGLALTPCVFPMYPILSGIIVGQGQKLST
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCH
AKAFTLSMAYVQGMAITYSILGLVVASAGMKYQAALQHPAVLIFLAILFFVLSLSMFGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCEE
DLKLPSSWQEKMNSISNNQKGGNLVGVFLMGVISGLVASPCTTAPLSGALVYVAQTGDLL
EECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHH
QGFLALYVLSMGMGVPLLIIGTSGGKLLPRAGAWMNIIKTVFGFLLIAVSIVMLGRIWTG
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVSDVLWSLWGISFTGYLMHQNKLSAFNWKQTVRSVLLTLTLLASFSYGFQAVMGHFGFT
HHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HAPMGTVATTEQEHGFKRIKSIEDLDREIAAATAAGKPVMLDLYADWCVACKEFEAITFK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEEEEC
DAEVLVRMNKIVLLQADVTKSDAVDVALLEKYNVLGLPTLLMFNEQGEQREDLRVTGFMG
CHHHHEEECEEEEEEECCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEECCC
PKEFAAHLDHLVK
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA