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The map label for this gene is yafC [C]

Identifier: 117921876

GI number: 117921876

Start: 4121231

End: 4122142

Strand: Direct

Name: yafC [C]

Synonym: Shewana3_3439

Alternate gene names: 117921876

Gene position: 4121231-4122142 (Clockwise)

Preceding gene: 117921872

Following gene: 117921878

Centisome position: 82.89

GC content: 47.37

Gene sequence:

>912_bases
ATGCCAGATTTAAACGGTATGATGCTATTTGCAGCCGTAGTTAGAGCGAAGGGATTCTCCCAAGCTGCACGTGAAACCGG
CCACCCAAAATCCACCATAAGTCGCAAAATCGCGCAGCTCGAAGAAGAACTTGGCGTGCGATTATTACAACGCGACACCC
GCAACTTAAGCCTTACTCAAGTCGGGGCCCTCTTTTATCAACACTGTGATTCCATTCGCAATGAGGTGGAAGCGGCCAAG
GCTGTTATCGAGAGTACCCATGATGATGTGTCAGGATCATTACGGATAGCTATTCCAGTCTCTTTTAGCCAAGAATTAAT
CGCTAACCTCTGTAGCGGATTCATGCGTTTATATCCCAATGTGGAATTAGATGTCCAGTTTACCGACAACGATATCGGTT
TAGTGGGTGAAGGATATGACATAGCTATCAAATATGGGCCACTGCAATCCTCTGATCTTGTTGCAAGATTACTGTTCGAG
CGCCAACCCATTCTCGTGGCAAGCCCGGCTTATTTAAAAGCCCGAGGCACGCCTGCTACACCCAAGGAATTAAGTGAACA
CAGTGGTATCTTACTCGGGACATCACGCTCTGCGCCCATTTGGCCACTGGGTAAAGGCGCGCGTAAGACCATGGTGAATT
TTCAACGTAAGGTTAGGGTTAATAGCCCTATTATGGTCAAGCAGTTAGCCCTCGATGACTTTGGCATTGCCATGCTGTCC
AACTCCGCCTGCAAGACGGAATTAGCGAATGGTCAACTGGTTCCCATACTACAAGAATGGCCAATCGAACCCTTTAAAGT
CTATGGGGTATATTCCAGCCGTCGCCAATTAGCCACTAATATTAGTGCCTTCTTGGACTTTTTCGTCAAACGCTTTAGTA
GCCAAGAAAGCCTGCAATCCTTGATGGGCTAA

Upstream 100 bases:

>100_bases
TCTGAAAATTTTTAGCCAATAAATATAACTTTGTTATCCCGCCAAATGCCATTAAACTGCATAAGACGCTATGTTCCAAA
TATGAGACAGTGGGAAAAAC

Downstream 100 bases:

>100_bases
GCACTTTATCGCAGCGACATTCTTTTTTATCTATATCGCCACTCCTTGATTCACATCCCTATGTTAAGTGACCATGCCAT
TGAGATAACAAAAAAGCCTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPDLNGMMLFAAVVRAKGFSQAARETGHPKSTISRKIAQLEEELGVRLLQRDTRNLSLTQVGALFYQHCDSIRNEVEAAK
AVIESTHDDVSGSLRIAIPVSFSQELIANLCSGFMRLYPNVELDVQFTDNDIGLVGEGYDIAIKYGPLQSSDLVARLLFE
RQPILVASPAYLKARGTPATPKELSEHSGILLGTSRSAPIWPLGKGARKTMVNFQRKVRVNSPIMVKQLALDDFGIAMLS
NSACKTELANGQLVPILQEWPIEPFKVYGVYSSRRQLATNISAFLDFFVKRFSSQESLQSLMG

Sequences:

>Translated_303_residues
MPDLNGMMLFAAVVRAKGFSQAARETGHPKSTISRKIAQLEEELGVRLLQRDTRNLSLTQVGALFYQHCDSIRNEVEAAK
AVIESTHDDVSGSLRIAIPVSFSQELIANLCSGFMRLYPNVELDVQFTDNDIGLVGEGYDIAIKYGPLQSSDLVARLLFE
RQPILVASPAYLKARGTPATPKELSEHSGILLGTSRSAPIWPLGKGARKTMVNFQRKVRVNSPIMVKQLALDDFGIAMLS
NSACKTELANGQLVPILQEWPIEPFKVYGVYSSRRQLATNISAFLDFFVKRFSSQESLQSLMG
>Mature_302_residues
PDLNGMMLFAAVVRAKGFSQAARETGHPKSTISRKIAQLEEELGVRLLQRDTRNLSLTQVGALFYQHCDSIRNEVEAAKA
VIESTHDDVSGSLRIAIPVSFSQELIANLCSGFMRLYPNVELDVQFTDNDIGLVGEGYDIAIKYGPLQSSDLVARLLFER
QPILVASPAYLKARGTPATPKELSEHSGILLGTSRSAPIWPLGKGARKTMVNFQRKVRVNSPIMVKQLALDDFGIAMLSN
SACKTELANGQLVPILQEWPIEPFKVYGVYSSRRQLATNISAFLDFFVKRFSSQESLQSLMG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=35.191637630662, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=29.8305084745763, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=27.891156462585, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=29.4314381270903, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1789440, Length=271, Percent_Identity=27.6752767527675, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=25.5172413793103, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=24.7457627118644, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789173, Length=296, Percent_Identity=23.6486486486486, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=24.7457627118644, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=177, Percent_Identity=31.638418079096, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786448, Length=255, Percent_Identity=25.8823529411765, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788481, Length=298, Percent_Identity=21.8120805369128, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33436; Mature: 33305

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLNGMMLFAAVVRAKGFSQAARETGHPKSTISRKIAQLEEELGVRLLQRDTRNLSLTQ
CCCCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VGALFYQHCDSIRNEVEAAKAVIESTHDDVSGSLRIAIPVSFSQELIANLCSGFMRLYPN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
VELDVQFTDNDIGLVGEGYDIAIKYGPLQSSDLVARLLFERQPILVASPAYLKARGTPAT
CEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCEEECCCCCC
PKELSEHSGILLGTSRSAPIWPLGKGARKTMVNFQRKVRVNSPIMVKQLALDDFGIAMLS
HHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHC
NSACKTELANGQLVPILQEWPIEPFKVYGVYSSRRQLATNISAFLDFFVKRFSSQESLQS
CCHHHHHHCCCCEEEEHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LMG
HCC
>Mature Secondary Structure 
PDLNGMMLFAAVVRAKGFSQAARETGHPKSTISRKIAQLEEELGVRLLQRDTRNLSLTQ
CCCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VGALFYQHCDSIRNEVEAAKAVIESTHDDVSGSLRIAIPVSFSQELIANLCSGFMRLYPN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
VELDVQFTDNDIGLVGEGYDIAIKYGPLQSSDLVARLLFERQPILVASPAYLKARGTPAT
CEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCEEECCCCCC
PKELSEHSGILLGTSRSAPIWPLGKGARKTMVNFQRKVRVNSPIMVKQLALDDFGIAMLS
HHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHC
NSACKTELANGQLVPILQEWPIEPFKVYGVYSSRRQLATNISAFLDFFVKRFSSQESLQS
CCHHHHHHCCCCEEEEHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LMG
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]