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The map label for this gene is 117921848

Identifier: 117921848

GI number: 117921848

Start: 4079364

End: 4081871

Strand: Reverse

Name: 117921848

Synonym: Shewana3_3411

Alternate gene names: NA

Gene position: 4081871-4079364 (Counterclockwise)

Preceding gene: 117921851

Following gene: 117921839

Centisome position: 82.09

GC content: 51.67

Gene sequence:

>2508_bases
ATGTCGATAAAACTCTCACCACTGGCGTTAGCAATTGCAGGAGCGATGACACTGTCAGCCGTGCCCGCTATGGCAAAAGA
TGCCCCTGTCTATGAAAAAGATGCCATTCTCGTGGTGTATAAAGACAATGCGACGAAGGCGGAGCGCTCGGCGGCTCAGC
GTTTAATTCGTGGCACCTTAACCGATGCCAATGCGGATGGTGTCGATGATAAGTTCCAGCATTTACTCAATGGCAAACTG
GCACGTTTAGCCCTGCGTAAGGGCACCAATATTGAAGATGCGATTAAGGTGATTAGCCGTCATCCGGCGGTAAAATATGC
CGAACCTAACTATATTCTCAAGGCTATTGGTACACCTGATGATCCAAGCTTTGCTAGCCTGTGGGGCATGAATAACACGG
GACAAAACGGTGGCACCGTCGATGCGGATATCGATGCTCCAGAAGCGTGGGAAATCACTACCGGCAGTTCGGATGTGGTG
ATTGGGGTGATTGACACAGGGGTGGATTACAATCATCCCGATCTACAGGCCAACATGTGGGTGAATGGTGGCGAGATCCC
AGGTAACGGCATCGACGATGACGGCAACGGCGTGATCGACGATGTTCACGGTTACAGCGCGGTCAACAATAACGGTAACC
CAATGGACGGCAACGGCCATGGTACCCATGTGTCTGGCACTATTGGCGCTAAAGGTAATAACGGCGTGGGTGTTGTTGGG
GTGAACTGGGACGTTAAAATCGCCGCCTGTCAGTTCCTCGATGCCGATGGTTATGGTTCTACCGCAGGCGCGATTGCCTG
TCTGGACTACTTTACCGATCTTAAGGTTAATCATGGGGTTGATATCAAAGCTACCAACAACTCTTGGGGCGGCGGCAGCT
TTAGCCAAGCCTTAAAAGATGCGATTGAAGCGGGTGGTGAAGCAGGCATTTTATTCGTTGCAGCAGCGGGTAATGACGCG
GTGGACAATGATGCCAGCCCACATTATCCCTCAAGCTATGACTCGGATGTGGTGTTGTCTATTGCCAGTACCGACCGTAA
TGACCGTATGTCAGATTTCTCACAGTGGGGCTTAACCAGTGTTGATATGGGCGCGCCTGGCACGGCGATTCTGTCAACCA
TCCCAGGCGGTGGCTATGCCACTTACTCTGGTACCTCAATGGCGACGCCCCATGTAACAGGTGCGGCAGCACTAGTGTGG
TCGTTAAATCCCGATCTCTCACCAGTAGAAATGAAAACCTTACTGATGGCATCGGGTGATGCGAATGCGGACCTCACCGG
TAAAACCGTAGCAGGGACTCGCCTCAATGTGGCAAATGCCTTAGAGCAGGCAAACCCATCCCCTAGCTATAAGTTTACCG
TATCGCCAGCATCGCAATCGGTCGAAGCGGGTAACACGGCTAGTTATAACTTTACTGTCGGTAGTGTGGCAGGGTGGGAA
GGTGATGTGGCGCTTAGCGTAGCCGTGTCTCCAGCGCTTGAAGGCGTATCCTTATCAGCCTCAACAGTTACAGCTGGTGG
TTCATTTACCTTAGATGTAGCGACAACGGCGCAAACAGCTTGGGGTGATTACAGCATTACAGTAACAGGTACCGATGGCA
CCATTGAAAAGTCTAAAGTCGTTGCACTGAATGTGTTCCCACAGGGATTAAATGACTTTAGCTATGGCAATGAAAACGCT
GTTGCTATCCCTGATAACAACACTAATGGCGTGGTAAGCACTATCGACGTTGCCGACGATGTGCAGATTTTTGGTGTGAC
CGCCGATGTGAATATCAGCCACACTTGGATTGGTGATTTACGTGTTGTGTTAACCTCTCCAGCGGGCACCGAAGTGGTTC
TGCATAACCGTGAGGGCGGCAGCGCCGACAACATCGTTAAGAGCTGGGACTTAAGCGCGTTTGACGGTGAAAATGCCCGT
GGTACTTGGTCATTATCTGTTGACGACAATGCGGGCGCGGATACGGGCACCCTGAATAACTGGGGCTTAGTGATCAGCGG
CTTAGGTGAAGCCTCTCCCGCGGCACCTGTAGCAGGTTTCGAGTATGCGGTTGAAGGCTTAAGCGTTGCCTTTACTAACA
CCAGTACCGATGCAAACGATGATATCGTGAGCTATAGCTGGGACTTTGGTGATGACACTAACTCTAGCGAAATGAACCCA
AGCCATGTGTTTGCTGCCGCTGGCACCTACAGAGTGTCGCTTACCGTGACTGACGCCATGGAGCATAGCAACACTGTGAC
TATGGAAGTGCAAGTGTATGAACATAGTATCAGTGCCACTGTCACTCGTGCGCTAGTCTCACGCCGTGGCAGTGCTATGG
TTGATCTCACATGGGATAGCGCCTTAGGTGAAAGCGTGGCCCTGTACCGTGATGGCGAGTTAGTGGCTACGACTGAAAAC
GATGGTAACTACCGCGATCGCTTTACAACGACGGCATCGAGTGTGACGTACCAAGTGTGTGAAACCTCGGGCTCACTCTG
TTCTGCGGCGGTTGTCGCGCAGTTCTAA

Upstream 100 bases:

>100_bases
ACATGCTGGATGTTCGTCGCTATTATCCAATCAATTTTGAGCGGAGGCTGCGTAATTGCGGTTCCAGAATTTCAACGTAA
AGGACTATAGGAAGCTCAAT

Downstream 100 bases:

>100_bases
TGAAGTCATAAAATAACAAGGCGACCCTAGGGTCGCCTTTTTTGTTATCTAAACTCGAAAGCTAAGGTTTTTCTTTCACT
TCCTCAGGCTCGGTTTCGGC

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 835; Mature: 834

Protein sequence:

>835_residues
MSIKLSPLALAIAGAMTLSAVPAMAKDAPVYEKDAILVVYKDNATKAERSAAQRLIRGTLTDANADGVDDKFQHLLNGKL
ARLALRKGTNIEDAIKVISRHPAVKYAEPNYILKAIGTPDDPSFASLWGMNNTGQNGGTVDADIDAPEAWEITTGSSDVV
IGVIDTGVDYNHPDLQANMWVNGGEIPGNGIDDDGNGVIDDVHGYSAVNNNGNPMDGNGHGTHVSGTIGAKGNNGVGVVG
VNWDVKIAACQFLDADGYGSTAGAIACLDYFTDLKVNHGVDIKATNNSWGGGSFSQALKDAIEAGGEAGILFVAAAGNDA
VDNDASPHYPSSYDSDVVLSIASTDRNDRMSDFSQWGLTSVDMGAPGTAILSTIPGGGYATYSGTSMATPHVTGAAALVW
SLNPDLSPVEMKTLLMASGDANADLTGKTVAGTRLNVANALEQANPSPSYKFTVSPASQSVEAGNTASYNFTVGSVAGWE
GDVALSVAVSPALEGVSLSASTVTAGGSFTLDVATTAQTAWGDYSITVTGTDGTIEKSKVVALNVFPQGLNDFSYGNENA
VAIPDNNTNGVVSTIDVADDVQIFGVTADVNISHTWIGDLRVVLTSPAGTEVVLHNREGGSADNIVKSWDLSAFDGENAR
GTWSLSVDDNAGADTGTLNNWGLVISGLGEASPAAPVAGFEYAVEGLSVAFTNTSTDANDDIVSYSWDFGDDTNSSEMNP
SHVFAAAGTYRVSLTVTDAMEHSNTVTMEVQVYEHSISATVTRALVSRRGSAMVDLTWDSALGESVALYRDGELVATTEN
DGNYRDRFTTTASSVTYQVCETSGSLCSAAVVAQF

Sequences:

>Translated_835_residues
MSIKLSPLALAIAGAMTLSAVPAMAKDAPVYEKDAILVVYKDNATKAERSAAQRLIRGTLTDANADGVDDKFQHLLNGKL
ARLALRKGTNIEDAIKVISRHPAVKYAEPNYILKAIGTPDDPSFASLWGMNNTGQNGGTVDADIDAPEAWEITTGSSDVV
IGVIDTGVDYNHPDLQANMWVNGGEIPGNGIDDDGNGVIDDVHGYSAVNNNGNPMDGNGHGTHVSGTIGAKGNNGVGVVG
VNWDVKIAACQFLDADGYGSTAGAIACLDYFTDLKVNHGVDIKATNNSWGGGSFSQALKDAIEAGGEAGILFVAAAGNDA
VDNDASPHYPSSYDSDVVLSIASTDRNDRMSDFSQWGLTSVDMGAPGTAILSTIPGGGYATYSGTSMATPHVTGAAALVW
SLNPDLSPVEMKTLLMASGDANADLTGKTVAGTRLNVANALEQANPSPSYKFTVSPASQSVEAGNTASYNFTVGSVAGWE
GDVALSVAVSPALEGVSLSASTVTAGGSFTLDVATTAQTAWGDYSITVTGTDGTIEKSKVVALNVFPQGLNDFSYGNENA
VAIPDNNTNGVVSTIDVADDVQIFGVTADVNISHTWIGDLRVVLTSPAGTEVVLHNREGGSADNIVKSWDLSAFDGENAR
GTWSLSVDDNAGADTGTLNNWGLVISGLGEASPAAPVAGFEYAVEGLSVAFTNTSTDANDDIVSYSWDFGDDTNSSEMNP
SHVFAAAGTYRVSLTVTDAMEHSNTVTMEVQVYEHSISATVTRALVSRRGSAMVDLTWDSALGESVALYRDGELVATTEN
DGNYRDRFTTTASSVTYQVCETSGSLCSAAVVAQF
>Mature_834_residues
SIKLSPLALAIAGAMTLSAVPAMAKDAPVYEKDAILVVYKDNATKAERSAAQRLIRGTLTDANADGVDDKFQHLLNGKLA
RLALRKGTNIEDAIKVISRHPAVKYAEPNYILKAIGTPDDPSFASLWGMNNTGQNGGTVDADIDAPEAWEITTGSSDVVI
GVIDTGVDYNHPDLQANMWVNGGEIPGNGIDDDGNGVIDDVHGYSAVNNNGNPMDGNGHGTHVSGTIGAKGNNGVGVVGV
NWDVKIAACQFLDADGYGSTAGAIACLDYFTDLKVNHGVDIKATNNSWGGGSFSQALKDAIEAGGEAGILFVAAAGNDAV
DNDASPHYPSSYDSDVVLSIASTDRNDRMSDFSQWGLTSVDMGAPGTAILSTIPGGGYATYSGTSMATPHVTGAAALVWS
LNPDLSPVEMKTLLMASGDANADLTGKTVAGTRLNVANALEQANPSPSYKFTVSPASQSVEAGNTASYNFTVGSVAGWEG
DVALSVAVSPALEGVSLSASTVTAGGSFTLDVATTAQTAWGDYSITVTGTDGTIEKSKVVALNVFPQGLNDFSYGNENAV
AIPDNNTNGVVSTIDVADDVQIFGVTADVNISHTWIGDLRVVLTSPAGTEVVLHNREGGSADNIVKSWDLSAFDGENARG
TWSLSVDDNAGADTGTLNNWGLVISGLGEASPAAPVAGFEYAVEGLSVAFTNTSTDANDDIVSYSWDFGDDTNSSEMNPS
HVFAAAGTYRVSLTVTDAMEHSNTVTMEVQVYEHSISATVTRALVSRRGSAMVDLTWDSALGESVALYRDGELVATTEND
GNYRDRFTTTASSVTYQVCETSGSLCSAAVVAQF

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI20336244, Length=454, Percent_Identity=25.9911894273128, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI76443679, Length=343, Percent_Identity=25.0728862973761, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4505579, Length=361, Percent_Identity=22.9916897506925, Blast_Score=67, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71983555, Length=605, Percent_Identity=22.8099173553719, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25141268, Length=326, Percent_Identity=24.5398773006135, Blast_Score=73, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320775, Length=443, Percent_Identity=29.1196388261851, Blast_Score=111, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324576, Length=380, Percent_Identity=30.7894736842105, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319893, Length=368, Percent_Identity=26.9021739130435, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17136192, Length=334, Percent_Identity=26.9461077844311, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 86480; Mature: 86349

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: PS00018 EF_HAND_1 ; PS50093 PKD ; PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKLSPLALAIAGAMTLSAVPAMAKDAPVYEKDAILVVYKDNATKAERSAAQRLIRGTL
CCEEECHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHC
TDANADGVDDKFQHLLNGKLARLALRKGTNIEDAIKVISRHPAVKYAEPNYILKAIGTPD
CCCCCCCCCHHHHHHHCCCEEEHHHHCCCCHHHHHHHHHCCCCEEECCCCEEEEECCCCC
DPSFASLWGMNNTGQNGGTVDADIDAPEAWEITTGSSDVVIGVIDTGVDYNHPDLQANMW
CCCHHEECCCCCCCCCCCEEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCEEEEE
VNGGEIPGNGIDDDGNGVIDDVHGYSAVNNNGNPMDGNGHGTHVSGTIGAKGNNGVGVVG
EECCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEEEE
VNWDVKIAACQFLDADGYGSTAGAIACLDYFTDLKVNHGVDIKATNNSWGGGSFSQALKD
ECCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHCEECCCEEEEECCCCCCCCHHHHHHHH
AIEAGGEAGILFVAAAGNDAVDNDASPHYPSSYDSDVVLSIASTDRNDRMSDFSQWGLTS
HHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCE
VDMGAPGTAILSTIPGGGYATYSGTSMATPHVTGAAALVWSLNPDLSPVEMKTLLMASGD
ECCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCC
ANADLTGKTVAGTRLNVANALEQANPSPSYKFTVSPASQSVEAGNTASYNFTVGSVAGWE
CCCCCCCCEECCCEEHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCC
GDVALSVAVSPALEGVSLSASTVTAGGSFTLDVATTAQTAWGDYSITVTGTDGTIEKSKV
CCEEEEEEECCCCCCCEEECEEEECCCEEEEEEEECCEECCCCEEEEEECCCCCCCCCEE
VALNVFPQGLNDFSYGNENAVAIPDNNTNGVVSTIDVADDVQIFGVTADVNISHTWIGDL
EEEEECCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCEEEEEEEEECEEEEEEECCE
RVVLTSPAGTEVVLHNREGGSADNIVKSWDLSAFDGENARGTWSLSVDDNAGADTGTLNN
EEEEECCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
WGLVISGLGEASPAAPVAGFEYAVEGLSVAFTNTSTDANDDIVSYSWDFGDDTNSSEMNP
CCEEEEECCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCC
SHVFAAAGTYRVSLTVTDAMEHSNTVTMEVQVYEHSISATVTRALVSRRGSAMVDLTWDS
CEEEEECCEEEEEEEEEEHHCCCCEEEEEEEEEECCHHHHHHHHHHHCCCCEEEEEEECC
ALGESVALYRDGELVATTENDGNYRDRFTTTASSVTYQVCETSGSLCSAAVVAQF
CCCCEEEEEECCEEEEEECCCCCCCCEEEECHHHEEEEEECCCCCHHHHHHEECC
>Mature Secondary Structure 
SIKLSPLALAIAGAMTLSAVPAMAKDAPVYEKDAILVVYKDNATKAERSAAQRLIRGTL
CEEECHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHC
TDANADGVDDKFQHLLNGKLARLALRKGTNIEDAIKVISRHPAVKYAEPNYILKAIGTPD
CCCCCCCCCHHHHHHHCCCEEEHHHHCCCCHHHHHHHHHCCCCEEECCCCEEEEECCCCC
DPSFASLWGMNNTGQNGGTVDADIDAPEAWEITTGSSDVVIGVIDTGVDYNHPDLQANMW
CCCHHEECCCCCCCCCCCEEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCEEEEE
VNGGEIPGNGIDDDGNGVIDDVHGYSAVNNNGNPMDGNGHGTHVSGTIGAKGNNGVGVVG
EECCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEEEE
VNWDVKIAACQFLDADGYGSTAGAIACLDYFTDLKVNHGVDIKATNNSWGGGSFSQALKD
ECCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHCEECCCEEEEECCCCCCCCHHHHHHHH
AIEAGGEAGILFVAAAGNDAVDNDASPHYPSSYDSDVVLSIASTDRNDRMSDFSQWGLTS
HHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCCE
VDMGAPGTAILSTIPGGGYATYSGTSMATPHVTGAAALVWSLNPDLSPVEMKTLLMASGD
ECCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCC
ANADLTGKTVAGTRLNVANALEQANPSPSYKFTVSPASQSVEAGNTASYNFTVGSVAGWE
CCCCCCCCEECCCEEHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCC
GDVALSVAVSPALEGVSLSASTVTAGGSFTLDVATTAQTAWGDYSITVTGTDGTIEKSKV
CCEEEEEEECCCCCCCEEECEEEECCCEEEEEEEECCEECCCCEEEEEECCCCCCCCCEE
VALNVFPQGLNDFSYGNENAVAIPDNNTNGVVSTIDVADDVQIFGVTADVNISHTWIGDL
EEEEECCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCEEEEEEEEECEEEEEEECCE
RVVLTSPAGTEVVLHNREGGSADNIVKSWDLSAFDGENARGTWSLSVDDNAGADTGTLNN
EEEEECCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
WGLVISGLGEASPAAPVAGFEYAVEGLSVAFTNTSTDANDDIVSYSWDFGDDTNSSEMNP
CCEEEEECCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCC
SHVFAAAGTYRVSLTVTDAMEHSNTVTMEVQVYEHSISATVTRALVSRRGSAMVDLTWDS
CEEEEECCEEEEEEEEEEHHCCCCEEEEEEEEEECCHHHHHHHHHHHCCCCEEEEEEECC
ALGESVALYRDGELVATTENDGNYRDRFTTTASSVTYQVCETSGSLCSAAVVAQF
CCCCEEEEEECCEEEEEECCCCCCCCEEEECHHHEEEEEECCCCCHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]