Click here to switch to the map view.

The map label for this gene is tas [H]

Identifier: 117921816

GI number: 117921816

Start: 4050318

End: 4051358

Strand: Direct

Name: tas [H]

Synonym: Shewana3_3379

Alternate gene names: 117921816

Gene position: 4050318-4051358 (Clockwise)

Preceding gene: 117921809

Following gene: 117921817

Centisome position: 81.46

GC content: 50.82

Gene sequence:

>1041_bases
ATGGAATACAGACGCATACCGCATTCTAATCTCGAGGTGAGCAAAATCTGTTTAGGCACTATGACTTGGGGTGAACAAAA
TACCCAAGCCGAAGCCTTCGCACAGCTAGACTACGCCATCGGCAGTGGCATCAACTTTATTGACACTGCGGAAATGTACC
CTGTGCCGCCAAAGCCAGAAACCCAAGGGGAAACCGAGCGCATTTTGGGCCAATACATTAAGGCCCGTGGCAACCGTGAT
GACCTAGTGATCGCCACTAAGATTGCCGCACCCGGCGGCAAGAGTGACTATATTCGCAAAAATATGGCGCTGGACTGGAA
CAATATCCATCAAGCGGTCGATGCTTCACTCGAACGCCTGCAAATCGATACTATCGATCTCTACCAAGTGCATTGGCCAG
ACCGCAATACCAACTTCTTCGGGGAATTATTTTACGACGAACAAGAGATTGAGCAGCAAACGCCAATCCTCGAGACCCTC
GAAGCCCTCGCCGAAGTGATTCGCCAAGGTAAAGTGCGCTATATCGGCGTATCGAACGAAACCCCTTGGGGACTAATGAA
GTATCTGCAACTGGCGGAAAAACACGGCCTGCCGCGCATTGTGACTGTGCAAAACCCCTATAACCTGCTCAACCGCAGCT
TTGAAGTGGGCATGAGTGAAATCAGCCATCGCGAAGAGTTGCCACTGCTGGCTTACTCGCCCTTGGCCTTTGGTGCCTTA
AGCGGTAAATATTGCAATAACCAATGGCCAGAAGGCGCGCGCTTAACCCTGTTTAAACGCTTCGCCCGTTACACGGGTTC
GCAAATGGCGCTCGATGCCACCGCAGCTTATGTAGACTTAGCCCGCGAGTTTAATCTCTCCCCCGCGCAAATGGCGTTAG
CCTTTGTTAACTCACGTAAATTTGTTGGCTCAAATATCATTGGCGCCACGGACTTATACCAGCTGAAAGAGAATATCGAC
AGCTTAAAGGTCAGCCTCTCCCCCGAGTTACTCAGCCGTCTCAATGCACTCTCAGATCAATTTAGATTGCCCTGCCCTTA
G

Upstream 100 bases:

>100_bases
TTATTTTTACTGCAGTAAAATGTTTGACGCCCTATTAACCTTTGCTTTACAGCAAAAGCTTGATAGCCTCGGACTAAGAT
AGTTTCCGTAGGAGAAATAG

Downstream 100 bases:

>100_bases
CTCTTAAAAGAGCGCTAACAATGAGCTGTTAAATTGAGTTTTTAAACAAGCCTCTAAAGTGAGTGGCCAAAGTGCCACTC
ACTTGAGTCACAGATTGATT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MEYRRIPHSNLEVSKICLGTMTWGEQNTQAEAFAQLDYAIGSGINFIDTAEMYPVPPKPETQGETERILGQYIKARGNRD
DLVIATKIAAPGGKSDYIRKNMALDWNNIHQAVDASLERLQIDTIDLYQVHWPDRNTNFFGELFYDEQEIEQQTPILETL
EALAEVIRQGKVRYIGVSNETPWGLMKYLQLAEKHGLPRIVTVQNPYNLLNRSFEVGMSEISHREELPLLAYSPLAFGAL
SGKYCNNQWPEGARLTLFKRFARYTGSQMALDATAAYVDLAREFNLSPAQMALAFVNSRKFVGSNIIGATDLYQLKENID
SLKVSLSPELLSRLNALSDQFRLPCP

Sequences:

>Translated_346_residues
MEYRRIPHSNLEVSKICLGTMTWGEQNTQAEAFAQLDYAIGSGINFIDTAEMYPVPPKPETQGETERILGQYIKARGNRD
DLVIATKIAAPGGKSDYIRKNMALDWNNIHQAVDASLERLQIDTIDLYQVHWPDRNTNFFGELFYDEQEIEQQTPILETL
EALAEVIRQGKVRYIGVSNETPWGLMKYLQLAEKHGLPRIVTVQNPYNLLNRSFEVGMSEISHREELPLLAYSPLAFGAL
SGKYCNNQWPEGARLTLFKRFARYTGSQMALDATAAYVDLAREFNLSPAQMALAFVNSRKFVGSNIIGATDLYQLKENID
SLKVSLSPELLSRLNALSDQFRLPCP
>Mature_346_residues
MEYRRIPHSNLEVSKICLGTMTWGEQNTQAEAFAQLDYAIGSGINFIDTAEMYPVPPKPETQGETERILGQYIKARGNRD
DLVIATKIAAPGGKSDYIRKNMALDWNNIHQAVDASLERLQIDTIDLYQVHWPDRNTNFFGELFYDEQEIEQQTPILETL
EALAEVIRQGKVRYIGVSNETPWGLMKYLQLAEKHGLPRIVTVQNPYNLLNRSFEVGMSEISHREELPLLAYSPLAFGAL
SGKYCNNQWPEGARLTLFKRFARYTGSQMALDATAAYVDLAREFNLSPAQMALAFVNSRKFVGSNIIGATDLYQLKENID
SLKVSLSPELLSRLNALSDQFRLPCP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=347, Percent_Identity=31.1239193083574, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI4504825, Length=344, Percent_Identity=31.1046511627907, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI27436962, Length=332, Percent_Identity=31.0240963855422, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI27436964, Length=332, Percent_Identity=31.0240963855422, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI27436966, Length=332, Percent_Identity=30.7228915662651, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI27436971, Length=350, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI223718702, Length=350, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI41327764, Length=351, Percent_Identity=26.2108262108262, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI41152114, Length=228, Percent_Identity=28.0701754385965, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=57.0605187319885, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI87081735, Length=350, Percent_Identity=31.1428571428571, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789375, Length=338, Percent_Identity=28.1065088757396, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788070, Length=340, Percent_Identity=27.0588235294118, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788081, Length=345, Percent_Identity=27.8260869565217, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787674, Length=320, Percent_Identity=26.25, Blast_Score=75, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319958, Length=318, Percent_Identity=27.6729559748428, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323998, Length=345, Percent_Identity=26.9565217391304, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=341, Percent_Identity=26.099706744868, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=269, Percent_Identity=27.1375464684015, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=353, Percent_Identity=24.6458923512748, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646159, Length=312, Percent_Identity=29.8076923076923, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646155, Length=180, Percent_Identity=31.6666666666667, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39117; Mature: 39117

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRRIPHSNLEVSKICLGTMTWGEQNTQAEAFAQLDYAIGSGINFIDTAEMYPVPPKPE
CCCCCCCCCCCCHHHHEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCC
TQGETERILGQYIKARGNRDDLVIATKIAAPGGKSDYIRKNMALDWNNIHQAVDASLERL
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHE
QIDTIDLYQVHWPDRNTNFFGELFYDEQEIEQQTPILETLEALAEVIRQGKVRYIGVSNE
ECCEEEEEEEECCCCCCCHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCC
TPWGLMKYLQLAEKHGLPRIVTVQNPYNLLNRSFEVGMSEISHREELPLLAYSPLAFGAL
CCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHCC
SGKYCNNQWPEGARLTLFKRFARYTGSQMALDATAAYVDLAREFNLSPAQMALAFVNSRK
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCH
FVGSNIIGATDLYQLKENIDSLKVSLSPELLSRLNALSDQFRLPCP
HCCCCCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEYRRIPHSNLEVSKICLGTMTWGEQNTQAEAFAQLDYAIGSGINFIDTAEMYPVPPKPE
CCCCCCCCCCCCHHHHEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCC
TQGETERILGQYIKARGNRDDLVIATKIAAPGGKSDYIRKNMALDWNNIHQAVDASLERL
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHE
QIDTIDLYQVHWPDRNTNFFGELFYDEQEIEQQTPILETLEALAEVIRQGKVRYIGVSNE
ECCEEEEEEEECCCCCCCHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCC
TPWGLMKYLQLAEKHGLPRIVTVQNPYNLLNRSFEVGMSEISHREELPLLAYSPLAFGAL
CCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHCC
SGKYCNNQWPEGARLTLFKRFARYTGSQMALDATAAYVDLAREFNLSPAQMALAFVNSRK
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCH
FVGSNIIGATDLYQLKENIDSLKVSLSPELLSRLNALSDQFRLPCP
HCCCCCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]