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The map label for this gene is nqrA [H]

Identifier: 117921815

GI number: 117921815

Start: 4048482

End: 4049852

Strand: Reverse

Name: nqrA [H]

Synonym: Shewana3_3378

Alternate gene names: 117921815

Gene position: 4049852-4048482 (Counterclockwise)

Preceding gene: 117921821

Following gene: 117921814

Centisome position: 81.45

GC content: 52.59

Gene sequence:

>1371_bases
ATGGCAGATTTTTCAAACCAAGTTATAACGATCAAAAAAGGCCTCGACTTGCCGATTTCGGGTGAGCCTCGGCAGATCAT
CGAACCCGGTAACAGGCCATCCCAAGTGGCTCTGTTGGGTGAGGAGTATGTTGGCTTAAAACCGACGATGTTGGTGGAAG
TCGGCGATAAGGTCAAAAAAGGCCAACCTTTGTTTGAAGATAAAAAAACAAAGGGCGTGCTATTTACCGCTCCCGCCAGT
GGTGAGATTGTTGCGATTCACCGTGGTGAACGTCGGGTGTTGCAATCAGTGGTGATCCGCTGCAATGGCTTAGACGCCGA
TGAGCAGATCCGTTTCGATATCCACACCGATTTACAGGCTCTATCTGCGGATGTGGTTAAAGCGCAACTGGTTAAGAGCG
GCCTGTGGACGGCGCTGCGTACCCGTCCTTTCTCCCGCGTTCCCGCACTAGATAGCAAACCCGCAGGTATTTTTGTCACG
GCAATGGATACCAATCCACTCGCCGCCGATCCTCGTTTGATTATTGCCGAGCAGCGCGATGCCTTTAAGGCGGGCTTAGC
GGTACTGAGTCATTTAACCGAGGGCAAGGTTTACCTCTGCCAAGACAAAGGCGAAGCCTTAGTTGGCGCCGATTTACCTA
AGGTTGAAGTGCGCCGTTTTACTGGGGTACATCCTGCCGGATTAGCCGGGACTCACATTCACTTTACCTTACCCGTCAGC
ATTGAGCGTCAGGTGTGGCATATCGGCTATCAAGACGTTATCGCCTACGGCAAGCTGTTCCAAACCGGTGAACTCTATAC
CGACCGCGTGGTGGCGCTGGGTGGCCCGAGCGTGCTTAACCCGCGTTTACTGCGCACTCAGTTAGGGGCAGAGCTGAGCG
CCTTAGTGGCCGACGAAGTTAAACCTGGTAACAACCGTGTGGTATCAGGCTCAGTGTTATCAGGCCATACCGCGAGGGGC
GTGCATGACTTTTTAGGTCGCTTCCACAACCAAGTATCTGTGCTCGCCGAAGATGTGCAGCACCAAGTATTGCCTTGGGT
CCGTGGCGGTTCGGACAAGTTCTCTATCACCCGTGCGGTAACTTCCCGTTTATTTGGCCTGACCAAGTCCTTCGAATTTA
CTACGCATCAAGGCGGCTCTCACCGCGCCATGATGGCCTTTGGTCAGCTCGATCGCGTTATGCCATTAGATATTTTACCC
ACTCTGCTAGTGCGTGACTTAGTGGTACGAGATACCGACGAGGCGCAGGCCTTAGGCGCATTGGAGTTAGATGAAGAAGA
TTTAGCCCTGTGTACCTTTGTGTGCCCCGGCAAGTATGACTTCGGTAAAGAGTTACGTGCCTGTCTAGATGTTATCGAGA
GGGAAGGTTAA

Upstream 100 bases:

>100_bases
ACTTACGAAATTGCGGCGGAATGTGACGCCAATATCGGATTATCTGTTAACAAACATCTACCCTAAATTTATCTAAAAAT
TTTCATGGTTGATATTTGTG

Downstream 100 bases:

>100_bases
TGACGACACAACCTAAAAAACCTGATTTACAGGACGACTATTACGCCACGGGTAAATCGATGAAGGGCTTTGTGCGCTCA
TTGGTGATCGCCAGTGGTCG

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MADFSNQVITIKKGLDLPISGEPRQIIEPGNRPSQVALLGEEYVGLKPTMLVEVGDKVKKGQPLFEDKKTKGVLFTAPAS
GEIVAIHRGERRVLQSVVIRCNGLDADEQIRFDIHTDLQALSADVVKAQLVKSGLWTALRTRPFSRVPALDSKPAGIFVT
AMDTNPLAADPRLIIAEQRDAFKAGLAVLSHLTEGKVYLCQDKGEALVGADLPKVEVRRFTGVHPAGLAGTHIHFTLPVS
IERQVWHIGYQDVIAYGKLFQTGELYTDRVVALGGPSVLNPRLLRTQLGAELSALVADEVKPGNNRVVSGSVLSGHTARG
VHDFLGRFHNQVSVLAEDVQHQVLPWVRGGSDKFSITRAVTSRLFGLTKSFEFTTHQGGSHRAMMAFGQLDRVMPLDILP
TLLVRDLVVRDTDEAQALGALELDEEDLALCTFVCPGKYDFGKELRACLDVIEREG

Sequences:

>Translated_456_residues
MADFSNQVITIKKGLDLPISGEPRQIIEPGNRPSQVALLGEEYVGLKPTMLVEVGDKVKKGQPLFEDKKTKGVLFTAPAS
GEIVAIHRGERRVLQSVVIRCNGLDADEQIRFDIHTDLQALSADVVKAQLVKSGLWTALRTRPFSRVPALDSKPAGIFVT
AMDTNPLAADPRLIIAEQRDAFKAGLAVLSHLTEGKVYLCQDKGEALVGADLPKVEVRRFTGVHPAGLAGTHIHFTLPVS
IERQVWHIGYQDVIAYGKLFQTGELYTDRVVALGGPSVLNPRLLRTQLGAELSALVADEVKPGNNRVVSGSVLSGHTARG
VHDFLGRFHNQVSVLAEDVQHQVLPWVRGGSDKFSITRAVTSRLFGLTKSFEFTTHQGGSHRAMMAFGQLDRVMPLDILP
TLLVRDLVVRDTDEAQALGALELDEEDLALCTFVCPGKYDFGKELRACLDVIEREG
>Mature_455_residues
ADFSNQVITIKKGLDLPISGEPRQIIEPGNRPSQVALLGEEYVGLKPTMLVEVGDKVKKGQPLFEDKKTKGVLFTAPASG
EIVAIHRGERRVLQSVVIRCNGLDADEQIRFDIHTDLQALSADVVKAQLVKSGLWTALRTRPFSRVPALDSKPAGIFVTA
MDTNPLAADPRLIIAEQRDAFKAGLAVLSHLTEGKVYLCQDKGEALVGADLPKVEVRRFTGVHPAGLAGTHIHFTLPVSI
ERQVWHIGYQDVIAYGKLFQTGELYTDRVVALGGPSVLNPRLLRTQLGAELSALVADEVKPGNNRVVSGSVLSGHTARGV
HDFLGRFHNQVSVLAEDVQHQVLPWVRGGSDKFSITRAVTSRLFGLTKSFEFTTHQGGSHRAMMAFGQLDRVMPLDILPT
LLVRDLVVRDTDEAQALGALELDEEDLALCTFVCPGKYDFGKELRACLDVIEREG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 49783; Mature: 49652

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFSNQVITIKKGLDLPISGEPRQIIEPGNRPSQVALLGEEYVGLKPTMLVEVGDKVKK
CCCCCCCEEEEECCCCCCCCCCCHHHCCCCCCCCEEEEECCCCCCCCCEEEEECCCHHHC
GQPLFEDKKTKGVLFTAPASGEIVAIHRGERRVLQSVVIRCNGLDADEQIRFDIHTDLQA
CCCCCCCCCCCCEEEECCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHH
LSADVVKAQLVKSGLWTALRTRPFSRVPALDSKPAGIFVTAMDTNPLAADPRLIIAEQRD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCHH
AFKAGLAVLSHLTEGKVYLCQDKGEALVGADLPKVEVRRFTGVHPAGLAGTHIHFTLPVS
HHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCHHHHHHCCCCCCCCCCCEEEEEEEEE
IERQVWHIGYQDVIAYGKLFQTGELYTDRVVALGGPSVLNPRLLRTQLGAELSALVADEV
ECCCEEECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHCC
KPGNNRVVSGSVLSGHTARGVHDFLGRFHNQVSVLAEDVQHQVLPWVRGGSDKFSITRAV
CCCCCEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
TSRLFGLTKSFEFTTHQGGSHRAMMAFGQLDRVMPLDILPTLLVRDLVVRDTDEAQALGA
HHHHHHCCCCCEEEECCCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCC
LELDEEDLALCTFVCPGKYDFGKELRACLDVIEREG
EEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADFSNQVITIKKGLDLPISGEPRQIIEPGNRPSQVALLGEEYVGLKPTMLVEVGDKVKK
CCCCCCEEEEECCCCCCCCCCCHHHCCCCCCCCEEEEECCCCCCCCCEEEEECCCHHHC
GQPLFEDKKTKGVLFTAPASGEIVAIHRGERRVLQSVVIRCNGLDADEQIRFDIHTDLQA
CCCCCCCCCCCCEEEECCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHH
LSADVVKAQLVKSGLWTALRTRPFSRVPALDSKPAGIFVTAMDTNPLAADPRLIIAEQRD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCHH
AFKAGLAVLSHLTEGKVYLCQDKGEALVGADLPKVEVRRFTGVHPAGLAGTHIHFTLPVS
HHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCHHHHHHCCCCCCCCCCCEEEEEEEEE
IERQVWHIGYQDVIAYGKLFQTGELYTDRVVALGGPSVLNPRLLRTQLGAELSALVADEV
ECCCEEECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHCC
KPGNNRVVSGSVLSGHTARGVHDFLGRFHNQVSVLAEDVQHQVLPWVRGGSDKFSITRAV
CCCCCEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
TSRLFGLTKSFEFTTHQGGSHRAMMAFGQLDRVMPLDILPTLLVRDLVVRDTDEAQALGA
HHHHHHCCCCCEEEECCCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCC
LELDEEDLALCTFVCPGKYDFGKELRACLDVIEREG
EEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA