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The map label for this gene is macB [H]

Identifier: 117921697

GI number: 117921697

Start: 3901143

End: 3902447

Strand: Reverse

Name: macB [H]

Synonym: Shewana3_3259

Alternate gene names: 117921697

Gene position: 3902447-3901143 (Counterclockwise)

Preceding gene: 117921698

Following gene: 117921696

Centisome position: 78.49

GC content: 49.35

Gene sequence:

>1305_bases
ATGTTCTTCTATTACTTAGATTTAGCTTGGCGTAGCATCAAAAAAACGCCCATGTTGTCGGCATTGATGATCATGGCGAT
TTCCATCGGCATTGGCATCACTATCACCACACTCAATATTTATAAAATGATGTCGATTAACCCCGCGGGGGAGAAATCCG
GCCAATTGTTTGCGGTGCAGCTATGGAGCCAAGGTCCAGATGCCTGGGATCGCTTCGATCAACAGATCACCTATCAAGAC
GGGATGAACTTACTTAAGAGTGATATTCCTAGCCTACAAACCCCCATGTTTCGCACGGGCGGCGCGGTGCAAACCGAAGA
TCCGGCTTTTTTACCCGTGCTGCAATCTCGAGTGCGGGTGACCAATAACGATTTTTTCCCACTGTTTGGCCTCGAGTTTC
AATATGGTCAGGCGTGGGATGACAGTGTTGATAAGGATGCTCGCTACGAAGTGGTGTTGACCGATGAGCTGAATAAGACG
CTGTTTGCGGGCCAAAATAGTGTCGGCAAGACAATTTATTTCAATGCTAAGCCCTATCAGGTGGTTGGAGTGCTTAAGCC
TTGGGCACCAAGTCCAAACTATTACGACCTTAACAACGGCGCCTTTGGCAATGTGGATACCTTGTTTGTCCCCTACAGCT
TAGCGCCGATTGAGGAATACGGCAGTTGGGGGAATACCAACGGCTGGAACTATGAAAGCATCAACACCTATGCACAGCGT
TTAACTTCGGAAAAGCATTGGACCCAGTATTGGGTGCAACTGGATACGCCTGAGCAAGTAGCTGAGTACCGTCAGTGGGT
ACGCCAATATATTGAACAACAAAAGAAATTAGGCCGCTTCAGCTCACCTAAGGCCGATGTGCAGTTGTCCGATGTTGACC
AATGGTTAGCCATCAATAAAGTGGTGCCGGAGGATAACAAGGTGCTGGTGGGCCTGAGTGCACTCTTCTTAATCGTCTGT
TTAGTCAATATGTTAGGGTTGTTGCTGTCTAAGTTTTTACGCCGTGCTCCCGAGATCGGCGTGCGCCGCGCCATCGGCGC
TAGCCAAGGGCAGATCTTTGCCCAACATATGGTGGAAGTGTCCTTGATGGGGTTATTCGGCGGTTTACTCGGCTTAGCTT
GGGCCTGGGGCTCACTGATGCTGCTGACCAAGAAGTTTGACTTGGAGGCGTCTTTAACTCACCTCGATACCAGTATGTGG
TTGATAGCACCAATGATCGCGATTTTGGCGGCTGTGGTGGCTGGTATCTACCCCGCGTGGCGTGTGTGTACGACTAACCC
AAGTGTTTATCTTAAGAGCCAATAA

Upstream 100 bases:

>100_bases
AAGTCTGCGACTTTACCATGTATCAACCTAATGCGGCCCGCAGTGCAAGCCACGGTAGTGTCGATAAACTGGTTGCTAAC
GCCCAAGGCTAGGAGCGGTT

Downstream 100 bases:

>100_bases
TCGGGGGCAATATGTTACATATCAAACCTATTCTCAGCAGTTTATTACGCAGTAAAAGCGGCCCCTTGTTGCTGTTATTA
CAGATCATTTTATCAGTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MFFYYLDLAWRSIKKTPMLSALMIMAISIGIGITITTLNIYKMMSINPAGEKSGQLFAVQLWSQGPDAWDRFDQQITYQD
GMNLLKSDIPSLQTPMFRTGGAVQTEDPAFLPVLQSRVRVTNNDFFPLFGLEFQYGQAWDDSVDKDARYEVVLTDELNKT
LFAGQNSVGKTIYFNAKPYQVVGVLKPWAPSPNYYDLNNGAFGNVDTLFVPYSLAPIEEYGSWGNTNGWNYESINTYAQR
LTSEKHWTQYWVQLDTPEQVAEYRQWVRQYIEQQKKLGRFSSPKADVQLSDVDQWLAINKVVPEDNKVLVGLSALFLIVC
LVNMLGLLLSKFLRRAPEIGVRRAIGASQGQIFAQHMVEVSLMGLFGGLLGLAWAWGSLMLLTKKFDLEASLTHLDTSMW
LIAPMIAILAAVVAGIYPAWRVCTTNPSVYLKSQ

Sequences:

>Translated_434_residues
MFFYYLDLAWRSIKKTPMLSALMIMAISIGIGITITTLNIYKMMSINPAGEKSGQLFAVQLWSQGPDAWDRFDQQITYQD
GMNLLKSDIPSLQTPMFRTGGAVQTEDPAFLPVLQSRVRVTNNDFFPLFGLEFQYGQAWDDSVDKDARYEVVLTDELNKT
LFAGQNSVGKTIYFNAKPYQVVGVLKPWAPSPNYYDLNNGAFGNVDTLFVPYSLAPIEEYGSWGNTNGWNYESINTYAQR
LTSEKHWTQYWVQLDTPEQVAEYRQWVRQYIEQQKKLGRFSSPKADVQLSDVDQWLAINKVVPEDNKVLVGLSALFLIVC
LVNMLGLLLSKFLRRAPEIGVRRAIGASQGQIFAQHMVEVSLMGLFGGLLGLAWAWGSLMLLTKKFDLEASLTHLDTSMW
LIAPMIAILAAVVAGIYPAWRVCTTNPSVYLKSQ
>Mature_434_residues
MFFYYLDLAWRSIKKTPMLSALMIMAISIGIGITITTLNIYKMMSINPAGEKSGQLFAVQLWSQGPDAWDRFDQQITYQD
GMNLLKSDIPSLQTPMFRTGGAVQTEDPAFLPVLQSRVRVTNNDFFPLFGLEFQYGQAWDDSVDKDARYEVVLTDELNKT
LFAGQNSVGKTIYFNAKPYQVVGVLKPWAPSPNYYDLNNGAFGNVDTLFVPYSLAPIEEYGSWGNTNGWNYESINTYAQR
LTSEKHWTQYWVQLDTPEQVAEYRQWVRQYIEQQKKLGRFSSPKADVQLSDVDQWLAINKVVPEDNKVLVGLSALFLIVC
LVNMLGLLLSKFLRRAPEIGVRRAIGASQGQIFAQHMVEVSLMGLFGGLLGLAWAWGSLMLLTKKFDLEASLTHLDTSMW
LIAPMIAILAAVVAGIYPAWRVCTTNPSVYLKSQ

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 48962; Mature: 48962

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00257 BOMBESIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFYYLDLAWRSIKKTPMLSALMIMAISIGIGITITTLNIYKMMSINPAGEKSGQLFAVQ
CEEEEEEHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCEEEEE
LWSQGPDAWDRFDQQITYQDGMNLLKSDIPSLQTPMFRTGGAVQTEDPAFLPVLQSRVRV
EECCCCHHHHHHHCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEE
TNNDFFPLFGLEFQYGQAWDDSVDKDARYEVVLTDELNKTLFAGQNSVGKTIYFNAKPYQ
CCCCCCEEECEEECCCCCCCCCCCCCCEEEEEEECCCCHHHCCCCCCCCCEEEECCCCEE
VVGVLKPWAPSPNYYDLNNGAFGNVDTLFVPYSLAPIEEYGSWGNTNGWNYESINTYAQR
EEEEECCCCCCCCEEECCCCCCCCCCEEEECCCCCCHHHHCCCCCCCCCCCHHHHHHHHH
LTSEKHWTQYWVQLDTPEQVAEYRQWVRQYIEQQKKLGRFSSPKADVQLSDVDQWLAINK
HCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHC
VVPEDNKVLVGLSALFLIVCLVNMLGLLLSKFLRRAPEIGVRRAIGASQGQIFAQHMVEV
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHH
SLMGLFGGLLGLAWAWGSLMLLTKKFDLEASLTHLDTSMWLIAPMIAILAAVVAGIYPAW
HHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RVCTTNPSVYLKSQ
EEEECCCCEEEECC
>Mature Secondary Structure
MFFYYLDLAWRSIKKTPMLSALMIMAISIGIGITITTLNIYKMMSINPAGEKSGQLFAVQ
CEEEEEEHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCEEEEE
LWSQGPDAWDRFDQQITYQDGMNLLKSDIPSLQTPMFRTGGAVQTEDPAFLPVLQSRVRV
EECCCCHHHHHHHCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEE
TNNDFFPLFGLEFQYGQAWDDSVDKDARYEVVLTDELNKTLFAGQNSVGKTIYFNAKPYQ
CCCCCCEEECEEECCCCCCCCCCCCCCEEEEEEECCCCHHHCCCCCCCCCEEEECCCCEE
VVGVLKPWAPSPNYYDLNNGAFGNVDTLFVPYSLAPIEEYGSWGNTNGWNYESINTYAQR
EEEEECCCCCCCCEEECCCCCCCCCCEEEECCCCCCHHHHCCCCCCCCCCCHHHHHHHHH
LTSEKHWTQYWVQLDTPEQVAEYRQWVRQYIEQQKKLGRFSSPKADVQLSDVDQWLAINK
HCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHC
VVPEDNKVLVGLSALFLIVCLVNMLGLLLSKFLRRAPEIGVRRAIGASQGQIFAQHMVEV
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHH
SLMGLFGGLLGLAWAWGSLMLLTKKFDLEASLTHLDTSMWLIAPMIAILAAVVAGIYPAW
HHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RVCTTNPSVYLKSQ
EEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]