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The map label for this gene is ndh [H]

Identifier: 117921561

GI number: 117921561

Start: 3749095

End: 3750384

Strand: Reverse

Name: ndh [H]

Synonym: Shewana3_3123

Alternate gene names: 117921561

Gene position: 3750384-3749095 (Counterclockwise)

Preceding gene: 117921562

Following gene: 117921559

Centisome position: 75.43

GC content: 43.72

Gene sequence:

>1290_bases
TTGGCTACGAAACGAATCGTGATAGTAGGTGGTGGGGCGGCAGGTTTAGCGCTAGCCTCTAAATTAGGCCGCAAGATGGG
CGGTAGTGATGTCGTCGATGTTTGCTTAATTGATAAAAGCCCAATCCATATTTGGAAGCCAAAATTACACGAAGTAGCTG
TTGGGGTTATTGACCAGTCTATAGAGGGATTGTTGTATAGAGATCATGGTCTTAAGAATGGTTATCGATACATTCGTGGC
GAAATTGAGCAATGTGAACCCGATGCCAAAACCATCCAACTTGCTGCGGTTTATAGTGACTCTGGTGAATTGCTGCTTGA
GCCCCGTCAAATTGAATACGATTACTTAGTGCTAGCCTTAGGCGGGGTCTCTAATAGTTTTAATACCTTAGGTGCTGAGA
AACATTGTATTTTCCTTGATAGTTTAGATAACGCTAACTTATTCCATCAAAAATTATTAGATGCATTACTGCAACTCAAT
GAAACACAAGAGAAAGTCAGTATAGGTATTGTTGGCGCAGGTGCCACTGGTGTCGAATTAGCCGCAGAGCTTCACCATGT
TATTGAGTCGGTGAAAGAGTATGGTTACCTCAATATCTCTAAGCATCATCTTGATGTGCATCTTATTGAAGCATCACCAA
AAATTCTCCCACAGTTACCCGAACGTGTGAGTGCAAGAGCTCAAGCGGTATTGGATAAAATTGGCATCCGTTTGCATATC
GGGGTGCAGGTTAAAGAAGTCACCCGCGATGGCTTTATTACACAGGATGGTGACGTTATCGAAGCGGGACTTAAAGTGTG
GGCGGCTGGTGTGAAAGGTCCAAAAGCGTTTCAAAACTTCTCTAAATTACCCATTACGCCTCGTAATCAAGTGGAAGTTG
ATGCTTGTATGCGAGTGAAAGGCCATCAAGATATTTATGCGCTTGGGGATTGCGCTCTATTAATTTTGGAGTCCGGCCAA
CCTGTGCCACCGCGCGCTCAAGCGGCAGCGCAAATGGCGGATACCTTGTATGAGAATATTGTGAACCGTTTGCAAGGGAA
GGCGGAAAAACCTTTTGTGTATAAAGACTATGGTTCTCTGGTGTCTCTAAGTCGTTTTTCTGCGGTCGGTAATCTAATGG
GGAATTTGCGTTCAGGGACTTTCTTCGTGGAAGGTCATATCGCAAGGATCATGTATATTTCGTTATACCAAAGACACTTA
GCGAGCCTATATGGCTGGTTCTCCGCAATTATTTATCGCATTGCACAAAAGTTACTCAAATGGCAAAGGCCAAAGCTGAA
ATTGCATTAA

Upstream 100 bases:

>100_bases
TTAATGCAAAATAGCCTCTTTAGTTAGACTAAAGTAGTTATCTCTTATCTGTTCCATGGTATAACTTAGCCACTTAAATA
GGCTTGTTGAGGTTGTTATT

Downstream 100 bases:

>100_bases
CTGAAAACAAAACAGAGAGCCTTGGCTCTCTGTGTTGTTTTAGCCTTGCTGAGCTAAAAATTAATGTTTGGGAGAGGCTG
AAGAGTCTCGGATCACAGGC

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MATKRIVIVGGGAAGLALASKLGRKMGGSDVVDVCLIDKSPIHIWKPKLHEVAVGVIDQSIEGLLYRDHGLKNGYRYIRG
EIEQCEPDAKTIQLAAVYSDSGELLLEPRQIEYDYLVLALGGVSNSFNTLGAEKHCIFLDSLDNANLFHQKLLDALLQLN
ETQEKVSIGIVGAGATGVELAAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQLPERVSARAQAVLDKIGIRLHI
GVQVKEVTRDGFITQDGDVIEAGLKVWAAGVKGPKAFQNFSKLPITPRNQVEVDACMRVKGHQDIYALGDCALLILESGQ
PVPPRAQAAAQMADTLYENIVNRLQGKAEKPFVYKDYGSLVSLSRFSAVGNLMGNLRSGTFFVEGHIARIMYISLYQRHL
ASLYGWFSAIIYRIAQKLLKWQRPKLKLH

Sequences:

>Translated_429_residues
MATKRIVIVGGGAAGLALASKLGRKMGGSDVVDVCLIDKSPIHIWKPKLHEVAVGVIDQSIEGLLYRDHGLKNGYRYIRG
EIEQCEPDAKTIQLAAVYSDSGELLLEPRQIEYDYLVLALGGVSNSFNTLGAEKHCIFLDSLDNANLFHQKLLDALLQLN
ETQEKVSIGIVGAGATGVELAAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQLPERVSARAQAVLDKIGIRLHI
GVQVKEVTRDGFITQDGDVIEAGLKVWAAGVKGPKAFQNFSKLPITPRNQVEVDACMRVKGHQDIYALGDCALLILESGQ
PVPPRAQAAAQMADTLYENIVNRLQGKAEKPFVYKDYGSLVSLSRFSAVGNLMGNLRSGTFFVEGHIARIMYISLYQRHL
ASLYGWFSAIIYRIAQKLLKWQRPKLKLH
>Mature_428_residues
ATKRIVIVGGGAAGLALASKLGRKMGGSDVVDVCLIDKSPIHIWKPKLHEVAVGVIDQSIEGLLYRDHGLKNGYRYIRGE
IEQCEPDAKTIQLAAVYSDSGELLLEPRQIEYDYLVLALGGVSNSFNTLGAEKHCIFLDSLDNANLFHQKLLDALLQLNE
TQEKVSIGIVGAGATGVELAAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQLPERVSARAQAVLDKIGIRLHIG
VQVKEVTRDGFITQDGDVIEAGLKVWAAGVKGPKAFQNFSKLPITPRNQVEVDACMRVKGHQDIYALGDCALLILESGQP
VPPRAQAAAQMADTLYENIVNRLQGKAEKPFVYKDYGSLVSLSRFSAVGNLMGNLRSGTFFVEGHIARIMYISLYQRHLA
SLYGWFSAIIYRIAQKLLKWQRPKLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=429, Percent_Identity=44.7552447552448, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6323515, Length=470, Percent_Identity=26.8085106382979, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320118, Length=447, Percent_Identity=26.1744966442953, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323794, Length=353, Percent_Identity=26.9121813031161, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47242; Mature: 47111

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKRIVIVGGGAAGLALASKLGRKMGGSDVVDVCLIDKSPIHIWKPKLHEVAVGVIDQS
CCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHH
IEGLLYRDHGLKNGYRYIRGEIEQCEPDAKTIQLAAVYSDSGELLLEPRQIEYDYLVLAL
HHHEEEECCCCCCCHHHHCCCHHHCCCCCCEEEEEEEEECCCCEEECCCCCCEEEEEEEE
GGVSNSFNTLGAEKHCIFLDSLDNANLFHQKLLDALLQLNETQEKVSIGIVGAGATGVEL
CCCCCCCHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHEEEEEEEECCCCHHHH
AAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQLPERVSARAQAVLDKIGIRLHI
HHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCHHHHCHHHHHHHHHHHHHHCCEEEEE
GVQVKEVTRDGFITQDGDVIEAGLKVWAAGVKGPKAFQNFSKLPITPRNQVEVDACMRVK
CEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCEEHHHHHEEC
GHQDIYALGDCALLILESGQPVPPRAQAAAQMADTLYENIVNRLQGKAEKPFVYKDYGSL
CCCCEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHH
VSLSRFSAVGNLMGNLRSGTFFVEGHIARIMYISLYQRHLASLYGWFSAIIYRIAQKLLK
HHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQRPKLKLH
CCCCCCCCC
>Mature Secondary Structure 
ATKRIVIVGGGAAGLALASKLGRKMGGSDVVDVCLIDKSPIHIWKPKLHEVAVGVIDQS
CCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHH
IEGLLYRDHGLKNGYRYIRGEIEQCEPDAKTIQLAAVYSDSGELLLEPRQIEYDYLVLAL
HHHEEEECCCCCCCHHHHCCCHHHCCCCCCEEEEEEEEECCCCEEECCCCCCEEEEEEEE
GGVSNSFNTLGAEKHCIFLDSLDNANLFHQKLLDALLQLNETQEKVSIGIVGAGATGVEL
CCCCCCCHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHEEEEEEEECCCCHHHH
AAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQLPERVSARAQAVLDKIGIRLHI
HHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCHHHHCHHHHHHHHHHHHHHCCEEEEE
GVQVKEVTRDGFITQDGDVIEAGLKVWAAGVKGPKAFQNFSKLPITPRNQVEVDACMRVK
CEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCEEHHHHHEEC
GHQDIYALGDCALLILESGQPVPPRAQAAAQMADTLYENIVNRLQGKAEKPFVYKDYGSL
CCCCEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHH
VSLSRFSAVGNLMGNLRSGTFFVEGHIARIMYISLYQRHLASLYGWFSAIIYRIAQKLLK
HHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQRPKLKLH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]