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The map label for this gene is hlyB [H]

Identifier: 117921554

GI number: 117921554

Start: 3738758

End: 3740245

Strand: Reverse

Name: hlyB [H]

Synonym: Shewana3_3116

Alternate gene names: 117921554

Gene position: 3740245-3738758 (Counterclockwise)

Preceding gene: 117921555

Following gene: 117921553

Centisome position: 75.22

GC content: 49.93

Gene sequence:

>1488_bases
ATGAAAACATTAGCCTTAAAAGTACAAATTGGGTTAGCAGCTGCGATATTTATGATAGTCAGCGTGCTATTTGGGGTGTC
CTATTGGTTGGCGAGCGATACCTTGGCCAGCAATGAAATGGCCTTTGAAGACAATACCGTTGCTAATCTTCAAGTCACCA
TGGCACAGCCGATTTTTACCTACGACTACGAGCAGATCCGTGCCGTATTGTCTGTCATGTTAAAGTCCGAGCAAATCTAT
CAAATTACCGTTGTGGATCATCGGGGCAAGTTGCTTGCCGAAGACAAACAAGCCGAGATCGTTGCCGCAAGTGACCTACA
AACAAGAGAGTTACAGTTCAGCGACCAAGGGAATCCGACCGGGCGTTTAACCATTGCCTTCTCTACTTTGCCGGTTAAGG
CGCAATTATCCGACTTACTGCTGGGGTACTTTTTACAGGCGCTGCTGATTCTAGCGGGCAGTCTGTTAGTGATTTTCATC
ATTCTCAAACGCTTAGTGATTAGTCCTCTGGATAAGGTCGTCGCTGCGTTAGAAGAAATCGCCAATGGTGATGGCGATCT
TAGCCACAGATTACCCGTGGAGAGCGAAGATGAAATCGGCAAACTCGCTAATGCTTTCAACGGTTTCGTCGAGCAAATTC
ATGGCACTATTACCAGAGTGCATGAAACCTCGGGTCTGCTATTGGGCGATGCTAAGGCACTGGGTACGCTGTCGCAAAGC
AACAATCAAAGGGTGCAGGCTCAGCTTAAAGAAACCGAAGCCGCGGTCACGGCCGTGACTCAATTGAGTGCCAGTGCCAA
CGAAGTGGCCATCAATGCAAAACGTACTGCCGATGCGGCAACCCAAGCCGATAGAGCGGTCGACGATGGCCAGCGTCAGT
TTGACTCGGGCTTAGCCATTACCCGTCAATTGGCGGGGGAATTAGCGCGTTCTGCCCAATCGGTATCGCAGCTACAACAG
GAAACCCAACGCATCGATGAAGTCGTGGTGGTGATCAGCAGCATTGCCGAACAGACTAATCTACTCGCCCTAAATGCCGC
CATTGAAGCCGCCAGAGCGGGTGAGCAAGGGCGTGGTTTTGCCGTTGTTGCCGATGAAGTGCGCTCTTTAGCGAGCCGTA
CCCAACAGGCGACGGGAGAAATCCAAAAAATGATCCAACAGGTGCAGAGCCGAGTTGCCGAAACCGTGAATGTGATGCAA
TCGAGCCAGACCCTCTCCAATCAAGGGGTCAACCGTTCGGAAGAAATTAAGCTCGTGCTGTCTAAAGTGACTGATTTAGT
TTCCAATATCAGTAATATGAATATCGAAGTTTCCCATGCGGCGCAGGAGCAGACCTGCGTCACCGAAGCGATTTCTCGTA
CGTTAAATGATCTTGCCAATGTCTCAGGTTCAGCCTCCCTCGATAGTGAGCACTTAGCACAATCGAGTGAGCGACTGTTT
CACCAAGGGGAAAGACTGCGGACGTTAGTAACTTCCTTCAGATTGTAG

Upstream 100 bases:

>100_bases
GCGTCATTATTCGTCTCGATACGCCCGATTTAAGTCCCTTAACCCCCATTGAACGCCAAGAGTTGTGGTTAGATCTATTT
AGTATGCAAGGTGCAAAATA

Downstream 100 bases:

>100_bases
CCATTTCTGAAGCTAGAAAAGGAATATCATGAATAAAACGATTGCCGCCACCGCGATTTTATTGGCTCTGGGCTTAACGG
CCTGTAGCGACGCGCCTAAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MKTLALKVQIGLAAAIFMIVSVLFGVSYWLASDTLASNEMAFEDNTVANLQVTMAQPIFTYDYEQIRAVLSVMLKSEQIY
QITVVDHRGKLLAEDKQAEIVAASDLQTRELQFSDQGNPTGRLTIAFSTLPVKAQLSDLLLGYFLQALLILAGSLLVIFI
ILKRLVISPLDKVVAALEEIANGDGDLSHRLPVESEDEIGKLANAFNGFVEQIHGTITRVHETSGLLLGDAKALGTLSQS
NNQRVQAQLKETEAAVTAVTQLSASANEVAINAKRTADAATQADRAVDDGQRQFDSGLAITRQLAGELARSAQSVSQLQQ
ETQRIDEVVVVISSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQQATGEIQKMIQQVQSRVAETVNVMQ
SSQTLSNQGVNRSEEIKLVLSKVTDLVSNISNMNIEVSHAAQEQTCVTEAISRTLNDLANVSGSASLDSEHLAQSSERLF
HQGERLRTLVTSFRL

Sequences:

>Translated_495_residues
MKTLALKVQIGLAAAIFMIVSVLFGVSYWLASDTLASNEMAFEDNTVANLQVTMAQPIFTYDYEQIRAVLSVMLKSEQIY
QITVVDHRGKLLAEDKQAEIVAASDLQTRELQFSDQGNPTGRLTIAFSTLPVKAQLSDLLLGYFLQALLILAGSLLVIFI
ILKRLVISPLDKVVAALEEIANGDGDLSHRLPVESEDEIGKLANAFNGFVEQIHGTITRVHETSGLLLGDAKALGTLSQS
NNQRVQAQLKETEAAVTAVTQLSASANEVAINAKRTADAATQADRAVDDGQRQFDSGLAITRQLAGELARSAQSVSQLQQ
ETQRIDEVVVVISSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQQATGEIQKMIQQVQSRVAETVNVMQ
SSQTLSNQGVNRSEEIKLVLSKVTDLVSNISNMNIEVSHAAQEQTCVTEAISRTLNDLANVSGSASLDSEHLAQSSERLF
HQGERLRTLVTSFRL
>Mature_495_residues
MKTLALKVQIGLAAAIFMIVSVLFGVSYWLASDTLASNEMAFEDNTVANLQVTMAQPIFTYDYEQIRAVLSVMLKSEQIY
QITVVDHRGKLLAEDKQAEIVAASDLQTRELQFSDQGNPTGRLTIAFSTLPVKAQLSDLLLGYFLQALLILAGSLLVIFI
ILKRLVISPLDKVVAALEEIANGDGDLSHRLPVESEDEIGKLANAFNGFVEQIHGTITRVHETSGLLLGDAKALGTLSQS
NNQRVQAQLKETEAAVTAVTQLSASANEVAINAKRTADAATQADRAVDDGQRQFDSGLAITRQLAGELARSAQSVSQLQQ
ETQRIDEVVVVISSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQQATGEIQKMIQQVQSRVAETVNVMQ
SSQTLSNQGVNRSEEIKLVLSKVTDLVSNISNMNIEVSHAAQEQTCVTEAISRTLNDLANVSGSASLDSEHLAQSSERLF
HQGERLRTLVTSFRL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=277, Percent_Identity=32.129963898917, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1787690, Length=357, Percent_Identity=29.4117647058824, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI2367378, Length=304, Percent_Identity=29.2763157894737, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788194, Length=357, Percent_Identity=28.8515406162465, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1789453, Length=355, Percent_Identity=28.4507042253521, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 53512; Mature: 53512

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLALKVQIGLAAAIFMIVSVLFGVSYWLASDTLASNEMAFEDNTVANLQVTMAQPIFT
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCEECCCCEEEEEEEEECCHHH
YDYEQIRAVLSVMLKSEQIYQITVVDHRGKLLAEDKQAEIVAASDLQTRELQFSDQGNPT
CCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCHHEEEECCCCCCC
GRLTIAFSTLPVKAQLSDLLLGYFLQALLILAGSLLVIFIILKRLVISPLDKVVAALEEI
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ANGDGDLSHRLPVESEDEIGKLANAFNGFVEQIHGTITRVHETSGLLLGDAKALGTLSQS
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCC
NNQRVQAQLKETEAAVTAVTQLSASANEVAINAKRTADAATQADRAVDDGQRQFDSGLAI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRQLAGELARSAQSVSQLQQETQRIDEVVVVISSIAEQTNLLALNAAIEAARAGEQGRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCE
AVVADEVRSLASRTQQATGEIQKMIQQVQSRVAETVNVMQSSQTLSNQGVNRSEEIKLVL
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SKVTDLVSNISNMNIEVSHAAQEQTCVTEAISRTLNDLANVSGSASLDSEHLAQSSERLF
HHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
HQGERLRTLVTSFRL
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLALKVQIGLAAAIFMIVSVLFGVSYWLASDTLASNEMAFEDNTVANLQVTMAQPIFT
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCEECCCCEEEEEEEEECCHHH
YDYEQIRAVLSVMLKSEQIYQITVVDHRGKLLAEDKQAEIVAASDLQTRELQFSDQGNPT
CCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCHHEEEECCCCCCC
GRLTIAFSTLPVKAQLSDLLLGYFLQALLILAGSLLVIFIILKRLVISPLDKVVAALEEI
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ANGDGDLSHRLPVESEDEIGKLANAFNGFVEQIHGTITRVHETSGLLLGDAKALGTLSQS
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCC
NNQRVQAQLKETEAAVTAVTQLSASANEVAINAKRTADAATQADRAVDDGQRQFDSGLAI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRQLAGELARSAQSVSQLQQETQRIDEVVVVISSIAEQTNLLALNAAIEAARAGEQGRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCE
AVVADEVRSLASRTQQATGEIQKMIQQVQSRVAETVNVMQSSQTLSNQGVNRSEEIKLVL
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SKVTDLVSNISNMNIEVSHAAQEQTCVTEAISRTLNDLANVSGSASLDSEHLAQSSERLF
HHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
HQGERLRTLVTSFRL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]