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The map label for this gene is dtpB [H]

Identifier: 117921527

GI number: 117921527

Start: 3704553

End: 3706103

Strand: Direct

Name: dtpB [H]

Synonym: Shewana3_3089

Alternate gene names: 117921527

Gene position: 3704553-3706103 (Clockwise)

Preceding gene: 117921525

Following gene: 117921528

Centisome position: 74.51

GC content: 49.65

Gene sequence:

>1551_bases
ATGACTCTTGGTACCAATCAGGTAAGCAAGACACATTCGTTTATGACAGTGTCGCTTATCGAATTGTGGGAACGTTTTGG
TTATTACGGCATGCAGGCGCTGATCGTGTACTTTATGGTGCAGCGTCTTGGCTTTGATGACTCCCGTGCAAACTTAGTTT
GGAGTGCCTGTGCGGCACTGATTTACGTGTCGCCGGCCATCGGCGGTTGGGTTGGGGATAAAATTCTCGGCACCAAACGC
ACTATGCTGCTCGGTGCGGGGATTTTGTCGGTAGGTTATGCATTGATGACAGTGCCGACCGAAAACACTTGGTTTATGTT
CTCCGCCCTTGGGGTGATTGTGGTCGGTAACGGCCTATTTAAACCCAATGCCGGTAACTTAGTCCGTAAGATTTACGAGG
GTGACGATTCTAAAATCGACAGCGCCTTTACCATCTACTACATGGCGGTAAACGTAGGTTCGACCTTCTCTATGCTGTTA
ACGCCTTGGATTAAGGACTATGTTAACGCGCAATACGGTAACGAATTTGGCTGGCATGCCGCCTTTGCGGTGTGCTGTGT
GGGCTTAATCGTCGGCTTAGGTAACTATGCCCTGATGCACAAGAGCCTCGCCAACTATGGTTCAGAGCCTGATACTCGCC
CTGTCAACAAGAAGAACTTGGCTATCGTCTTAGTCTTAGCGGCGCTTTCCGTTGTGGCTTCAGCCATTATTCTTGAATAT
GAAGATGTTGCTCGAGTATTCGTGTATGCCGCGGGTGTGGCGGTATTAGGAATTTTCTTCCACTTAATTCGTACCAGTGA
GCCAAGTGAGCGGGCCGGCCTTATCGCAGCGCTAATCCTTACGGTGCAGACCGTCTTCTTCTTTATCTTCTATCAACAAA
TGTCGACCTCACTGGCTCTGTTTGCACTGCGTAACGTCGATTGGGATTTCCAAGTCTTTGGCACCCATTTGTGGACTTGG
TCTCCTGCGCAGTTCCAAGCACTGAACCCAATCTGGATCATGGTGTTAAGCCCAGTTCTGGCTTGGAGTTATTCATGGGC
AGGTCGCAACAATAAGGACTTTTCGATTGCCGCTAAGTTCGCCTTAGGTTTTGCGGTTGTCGCGATAGGCTTCTTTATCT
ACGGTTTTGCAGGCCAATTTGCCGTTGAGGGTAAGACCTCTTCTTGGGTGATGATTTGGGGTTATGCTTCTTACTCACTC
GGCGAACTGCTGGTGAGTGGTCTTGGTTTAGCCATGATCGCCCGCTATGTCCCCGCTCGCATGGGCGGCTTTATGATGGG
CGCGTATTTCGTGGCATCGGGTATTTCACAGTACTTAGGCGGCGTTGTGGCTAACTTTGCCAGCGTGCCACAGGACTTAG
TCGACCCGCTGCAAACTCTGCCAGTTTATACCAATCTATTCAATAAATTAGGTATTGCGGCCGTGGTCTGTACTTTCATC
GCCTTAGCCGTATTACCTCTGATGCGCCGTTTGACCGAAAGTCATCACGCCCATAACAGTATTGAAGATAACGCTGCGGC
CTCACTACGTGATGTGAAAGCCGAGCAATAA

Upstream 100 bases:

>100_bases
AACAAAGTCTATTCTGCGGCGTTGTGGCATTGGTTTGCGCAGACTATCGCCTTATACTCTTGGCCTCTAACACAAAACAA
CAATAACGGAAGCAAGCTTT

Downstream 100 bases:

>100_bases
TCCTCCGACTCACATACGCCATATGTGAGCGCTAAAAACTGCCGACAAGCCCCGCTTGCGGCAGTTTTTTTATACCTTTA
GGTTACTGCTCATCACCAAA

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MTLGTNQVSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAALIYVSPAIGGWVGDKILGTKR
TMLLGAGILSVGYALMTVPTENTWFMFSALGVIVVGNGLFKPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGSTFSMLL
TPWIKDYVNAQYGNEFGWHAAFAVCCVGLIVGLGNYALMHKSLANYGSEPDTRPVNKKNLAIVLVLAALSVVASAIILEY
EDVARVFVYAAGVAVLGIFFHLIRTSEPSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRNVDWDFQVFGTHLWTW
SPAQFQALNPIWIMVLSPVLAWSYSWAGRNNKDFSIAAKFALGFAVVAIGFFIYGFAGQFAVEGKTSSWVMIWGYASYSL
GELLVSGLGLAMIARYVPARMGGFMMGAYFVASGISQYLGGVVANFASVPQDLVDPLQTLPVYTNLFNKLGIAAVVCTFI
ALAVLPLMRRLTESHHAHNSIEDNAAASLRDVKAEQ

Sequences:

>Translated_516_residues
MTLGTNQVSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAALIYVSPAIGGWVGDKILGTKR
TMLLGAGILSVGYALMTVPTENTWFMFSALGVIVVGNGLFKPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGSTFSMLL
TPWIKDYVNAQYGNEFGWHAAFAVCCVGLIVGLGNYALMHKSLANYGSEPDTRPVNKKNLAIVLVLAALSVVASAIILEY
EDVARVFVYAAGVAVLGIFFHLIRTSEPSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRNVDWDFQVFGTHLWTW
SPAQFQALNPIWIMVLSPVLAWSYSWAGRNNKDFSIAAKFALGFAVVAIGFFIYGFAGQFAVEGKTSSWVMIWGYASYSL
GELLVSGLGLAMIARYVPARMGGFMMGAYFVASGISQYLGGVVANFASVPQDLVDPLQTLPVYTNLFNKLGIAAVVCTFI
ALAVLPLMRRLTESHHAHNSIEDNAAASLRDVKAEQ
>Mature_515_residues
TLGTNQVSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAALIYVSPAIGGWVGDKILGTKRT
MLLGAGILSVGYALMTVPTENTWFMFSALGVIVVGNGLFKPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGSTFSMLLT
PWIKDYVNAQYGNEFGWHAAFAVCCVGLIVGLGNYALMHKSLANYGSEPDTRPVNKKNLAIVLVLAALSVVASAIILEYE
DVARVFVYAAGVAVLGIFFHLIRTSEPSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRNVDWDFQVFGTHLWTWS
PAQFQALNPIWIMVLSPVLAWSYSWAGRNNKDFSIAAKFALGFAVVAIGFFIYGFAGQFAVEGKTSSWVMIWGYASYSLG
ELLVSGLGLAMIARYVPARMGGFMMGAYFVASGISQYLGGVVANFASVPQDLVDPLQTLPVYTNLFNKLGIAAVVCTFIA
LAVLPLMRRLTESHHAHNSIEDNAAASLRDVKAEQ

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=399, Percent_Identity=21.0526315789474, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI226371746, Length=357, Percent_Identity=21.8487394957983, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789911, Length=499, Percent_Identity=38.0761523046092, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI1787922, Length=494, Percent_Identity=36.8421052631579, Blast_Score=345, Evalue=5e-96,
Organism=Escherichia coli, GI1790572, Length=508, Percent_Identity=29.9212598425197, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1786927, Length=501, Percent_Identity=28.3433133732535, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71987453, Length=375, Percent_Identity=24, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17569141, Length=180, Percent_Identity=25, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24639583, Length=185, Percent_Identity=28.6486486486486, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639585, Length=185, Percent_Identity=28.6486486486486, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639581, Length=185, Percent_Identity=28.6486486486486, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571098, Length=336, Percent_Identity=25, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571102, Length=336, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571100, Length=336, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 56466; Mature: 56335

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLGTNQVSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAAL
CCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IYVSPAIGGWVGDKILGTKRTMLLGAGILSVGYALMTVPTENTWFMFSALGVIVVGNGLF
HHHCCHHCCHHCCHHHCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHCCHHEECCCCC
KPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGSTFSMLLTPWIKDYVNAQYGNEFGWHA
CCCHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHH
AFAVCCVGLIVGLGNYALMHKSLANYGSEPDTRPVNKKNLAIVLVLAALSVVASAIILEY
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EDVARVFVYAAGVAVLGIFFHLIRTSEPSERAGLIAALILTVQTVFFFIFYQQMSTSLAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FALRNVDWDFQVFGTHLWTWSPAQFQALNPIWIMVLSPVLAWSYSWAGRNNKDFSIAAKF
HHHHCCCCCCEEECCEEEECCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ALGFAVVAIGFFIYGFAGQFAVEGKTSSWVMIWGYASYSLGELLVSGLGLAMIARYVPAR
HHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
MGGFMMGAYFVASGISQYLGGVVANFASVPQDLVDPLQTLPVYTNLFNKLGIAAVVCTFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAVLPLMRRLTESHHAHNSIEDNAAASLRDVKAEQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TLGTNQVSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAAL
CCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IYVSPAIGGWVGDKILGTKRTMLLGAGILSVGYALMTVPTENTWFMFSALGVIVVGNGLF
HHHCCHHCCHHCCHHHCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHCCHHEECCCCC
KPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGSTFSMLLTPWIKDYVNAQYGNEFGWHA
CCCHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHH
AFAVCCVGLIVGLGNYALMHKSLANYGSEPDTRPVNKKNLAIVLVLAALSVVASAIILEY
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EDVARVFVYAAGVAVLGIFFHLIRTSEPSERAGLIAALILTVQTVFFFIFYQQMSTSLAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FALRNVDWDFQVFGTHLWTWSPAQFQALNPIWIMVLSPVLAWSYSWAGRNNKDFSIAAKF
HHHHCCCCCCEEECCEEEECCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ALGFAVVAIGFFIYGFAGQFAVEGKTSSWVMIWGYASYSLGELLVSGLGLAMIARYVPAR
HHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
MGGFMMGAYFVASGISQYLGGVVANFASVPQDLVDPLQTLPVYTNLFNKLGIAAVVCTFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAVLPLMRRLTESHHAHNSIEDNAAASLRDVKAEQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA