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The map label for this gene is gcp [H]

Identifier: 117921521

GI number: 117921521

Start: 3695729

End: 3696745

Strand: Reverse

Name: gcp [H]

Synonym: Shewana3_3083

Alternate gene names: 117921521

Gene position: 3696745-3695729 (Counterclockwise)

Preceding gene: 117921526

Following gene: 117921519

Centisome position: 74.35

GC content: 52.8

Gene sequence:

>1017_bases
ATGCGGGTTCTAGGTATTGAGACATCTTGTGACGAGACAGGTATTGCCGTCTATGACGATAAGCTGGGATTGCTCTCCCA
TGCTTTATATAGTCAGGTTAAGTTGCATGCGGATTATGGTGGAGTTGTGCCTGAACTGGCTTCCCGCGACCATGTGCGCA
AAATTGTCCCGCTGATCCGCCAAGCGCTGAAAAATGCCAATACCGAGATTGCCGATTTAGATGGGATTGCCTACACCAAA
GGCCCAGGCCTTATCGGTGCTTTATTAGTGGGCGCTTGTGTTGGCCGCTCACTTGCCTTTGCTTGGAATAAACCCGCCAT
CGGTGTGCACCATATGGAAGGGCATCTGCTGGCGCCAATGCTGGAAGACGATGCGCCTGAGTTTCCCTTTGTGGCACTGT
TAGTGTCTGGTGGCCACTCCATGTTAGTAAAGGTCGATGGTATCGGCCTTTATGAAGTCTTAGGTGAGTCGGTGGATGAC
GCCGCCGGTGAAGCCTTCGATAAAACCGCTAAGTTAATGGGGCTGGATTATCCTGGCGGTCCACGGCTTGCGAAACTGGC
CGCCAAAGGTGAGCCAGCAGGTTATCAATTTCCGCGCCCAATGACCGACAGACCCGGACTCGATTTTAGTTTCTCAGGGC
TGAAAACCTTTACCGCCAATACCATTGCCGCCGAGCCCGATGATGAGCAAACCCGCGCGAACATCGCCCGCGCTTTTGAA
GAAGCGGTCGTTGATACGCTCGCGATTAAATGTCGCCGCGCGTTAAAACAAACAGGCTATAACCGTTTAGTGATCGCCGG
TGGCGTGAGTGCCAACACGCGCCTACGGGAAACCTTGGCCGAGATGATGACCTCTATCGGTGGCCGAGTTTATTATCCAC
GTGGTGAATTCTGTACTGACAATGGTGCCATGATTGCCTTTGCTGGCCTGCAGCGTTTAAAGGCGGGGCAACAGGAAGAC
TTAGCTGTCAAAGGTCAACCTAGATGGCCGCTTGATACCTTACCGCCTGTTGCATGA

Upstream 100 bases:

>100_bases
GTGGCGGGTTTGGCTACGGGAATATGATGATCGGCGACTGGAGTAATTGTCATCATACAGGTAGAATTAGCGCCCTTTGG
TTATTTGGATATGAGGCACC

Downstream 100 bases:

>100_bases
GTTATCGCAAGCTAAGTCAGCAAAATAAAAAACAGCGCATAATGCGCTGTTTTTTTTATGGTTATCTTGGATTGTTCTCT
TGGATTAGTCACTTGCATAT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRVLGIETSCDETGIAVYDDKLGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKNANTEIADLDGIAYTK
GPGLIGALLVGACVGRSLAFAWNKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGLYEVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAAKGEPAGYQFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMTSIGGRVYYPRGEFCTDNGAMIAFAGLQRLKAGQQED
LAVKGQPRWPLDTLPPVA

Sequences:

>Translated_338_residues
MRVLGIETSCDETGIAVYDDKLGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKNANTEIADLDGIAYTK
GPGLIGALLVGACVGRSLAFAWNKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGLYEVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAAKGEPAGYQFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMTSIGGRVYYPRGEFCTDNGAMIAFAGLQRLKAGQQED
LAVKGQPRWPLDTLPPVA
>Mature_338_residues
MRVLGIETSCDETGIAVYDDKLGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKNANTEIADLDGIAYTK
GPGLIGALLVGACVGRSLAFAWNKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGLYEVLGESVDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAAKGEPAGYQFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMTSIGGRVYYPRGEFCTDNGAMIAFAGLQRLKAGQQED
LAVKGQPRWPLDTLPPVA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=355, Percent_Identity=34.0845070422535, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI8923380, Length=328, Percent_Identity=32.9268292682927, Blast_Score=145, Evalue=7e-35,
Organism=Escherichia coli, GI1789445, Length=335, Percent_Identity=74.3283582089552, Blast_Score=511, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=30.0911854103343, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=325, Percent_Identity=33.5384615384615, Blast_Score=143, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320099, Length=376, Percent_Identity=32.9787234042553, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=27.5862068965517, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI20129063, Length=341, Percent_Identity=34.3108504398827, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21357207, Length=331, Percent_Identity=31.7220543806647, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36190; Mature: 36190

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGIAVYDDKLGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIR
CEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
QALKNANTEIADLDGIAYTKGPGLIGALLVGACVGRSLAFAWNKPAIGVHHMEGHLLAPM
HHHHCCCCCEEECCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCEECCH
LEDDAPEFPFVALLVSGGHSMLVKVDGIGLYEVLGESVDDAAGEAFDKTAKLMGLDYPGG
HCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
PRLAKLAAKGEPAGYQFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
CHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCEEEECCEEECCCCCHHHHHHHHHHHH
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMTSIGGRVYYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCEECC
NGAMIAFAGLQRLKAGQQEDLAVKGQPRWPLDTLPPVA
CCCEEEHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLGIETSCDETGIAVYDDKLGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIR
CEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
QALKNANTEIADLDGIAYTKGPGLIGALLVGACVGRSLAFAWNKPAIGVHHMEGHLLAPM
HHHHCCCCCEEECCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCEECCH
LEDDAPEFPFVALLVSGGHSMLVKVDGIGLYEVLGESVDDAAGEAFDKTAKLMGLDYPGG
HCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
PRLAKLAAKGEPAGYQFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFE
CHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCEEEECCEEECCCCCHHHHHHHHHHHH
EAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMTSIGGRVYYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCEECC
NGAMIAFAGLQRLKAGQQEDLAVKGQPRWPLDTLPPVA
CCCEEEHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA