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The map label for this gene is rlmA [H]

Identifier: 117921516

GI number: 117921516

Start: 3692017

End: 3692856

Strand: Reverse

Name: rlmA [H]

Synonym: Shewana3_3078

Alternate gene names: 117921516

Gene position: 3692856-3692017 (Counterclockwise)

Preceding gene: 117921517

Following gene: 117921513

Centisome position: 74.27

GC content: 47.62

Gene sequence:

>840_bases
ATGGGCCTTCAATTTCAATGTCCTACCTGTGGTTTGGCACTGATGCAGCATCAGGCATCCCAAGGTTTTTACTGTGCGAA
TAAGCACCATTTTGATAAAAATGAAGCGGGTTATTGGATTTTTACTAAACCAGCACGACAAAAGCCGACTGGCGACTCCC
GTCAGCAAGTGCGGGCAAAGCGCTTCTTGCTTGAGTCGGGGATTTTTTCACCTTTAGTTGAAAAAATGGCGGCGATGATC
GCCCCCCATCTCAAAGCGGATGATTGCCTATTGGACTACGAGTGCGCTGACGGCTTCTATTTGCGTGCTTTAGCTTCTGC
GCTACTTAATCTCACAAACGAGCTAAACGTCCAGTACAGCGGCGTAGCGGACGCAGAAAATACTATTTTTGCTGCGGCCA
AAGCGCAAACCCCTGCAACACTCTGCTTAAGCACCTCAAAAGTGCTGCCTTTTGCCGACAATTGCACTGACCTTATCACC
GTGGTCGATAAGCCGTTGAAGGGGAAGGAATGCGTTCGAGTCCTTAAGGAGCAGGGCTTGATGTTACAGGTGATCCCGGG
TGCGCGGCATTTGTGGCAAATCAGGGAGTGTATTTATCCAGAACTGACTGAAAAAACTCCTCAAATTAATTTGCCTTCGG
GATTAATTGTCAAAGAGCAGCAACGATTACAATTTAGTTTGTCTGTGACGGGTGAACAAGCGCTGGTCTTGCTAGATATG
ACACCCTATGCGTGGCGCGCCTCCGAACAAGTCAAACACCTTATTCGGACGAAAGCCTTCGATGTGCTGGAAATTGATTT
TGTTTTGGTCTTGGCGCAGAAGTCTTTAATTGAGTCCTAA

Upstream 100 bases:

>100_bases
ATTTATCTTCCTATAATACAGGGGCGTCATGGCTAAAAAATCGGGTCTAGTACCCGATTTTTGTGTTTTTAGGCGCGGAT
TTTCGTTAACGGAGTAAGTT

Downstream 100 bases:

>100_bases
CAGGCCAAAATACAAAATTAAATAGGATGTTTTTTAGTCTATTCATTAGCTTAGGGAATGCGTTTCTGGGTGCTTGAATA
GGGCGAATTGCGCAAGTCTA

Product: ribosomal RNA large subunit methyltransferase A

Products: NA

Alternate protein names: 23S rRNA m1G745 methyltransferase; rRNA (guanine-N(1)-)-methyltransferase [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MGLQFQCPTCGLALMQHQASQGFYCANKHHFDKNEAGYWIFTKPARQKPTGDSRQQVRAKRFLLESGIFSPLVEKMAAMI
APHLKADDCLLDYECADGFYLRALASALLNLTNELNVQYSGVADAENTIFAAAKAQTPATLCLSTSKVLPFADNCTDLIT
VVDKPLKGKECVRVLKEQGLMLQVIPGARHLWQIRECIYPELTEKTPQINLPSGLIVKEQQRLQFSLSVTGEQALVLLDM
TPYAWRASEQVKHLIRTKAFDVLEIDFVLVLAQKSLIES

Sequences:

>Translated_279_residues
MGLQFQCPTCGLALMQHQASQGFYCANKHHFDKNEAGYWIFTKPARQKPTGDSRQQVRAKRFLLESGIFSPLVEKMAAMI
APHLKADDCLLDYECADGFYLRALASALLNLTNELNVQYSGVADAENTIFAAAKAQTPATLCLSTSKVLPFADNCTDLIT
VVDKPLKGKECVRVLKEQGLMLQVIPGARHLWQIRECIYPELTEKTPQINLPSGLIVKEQQRLQFSLSVTGEQALVLLDM
TPYAWRASEQVKHLIRTKAFDVLEIDFVLVLAQKSLIES
>Mature_278_residues
GLQFQCPTCGLALMQHQASQGFYCANKHHFDKNEAGYWIFTKPARQKPTGDSRQQVRAKRFLLESGIFSPLVEKMAAMIA
PHLKADDCLLDYECADGFYLRALASALLNLTNELNVQYSGVADAENTIFAAAKAQTPATLCLSTSKVLPFADNCTDLITV
VDKPLKGKECVRVLKEQGLMLQVIPGARHLWQIRECIYPELTEKTPQINLPSGLIVKEQQRLQFSLSVTGEQALVLLDMT
PYAWRASEQVKHLIRTKAFDVLEIDFVLVLAQKSLIES

Specific function: Specifically methylates the guanosine in position 745 of 23S rRNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmA family [H]

Homologues:

Organism=Escherichia coli, GI1788125, Length=278, Percent_Identity=32.0143884892086, Blast_Score=144, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR016718 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.187 [H]

Molecular weight: Translated: 31160; Mature: 31028

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLQFQCPTCGLALMQHQASQGFYCANKHHFDKNEAGYWIFTKPARQKPTGDSRQQVRAK
CCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
RFLLESGIFSPLVEKMAAMIAPHLKADDCLLDYECADGFYLRALASALLNLTNELNVQYS
HHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEC
GVADAENTIFAAAKAQTPATLCLSTSKVLPFADNCTDLITVVDKPLKGKECVRVLKEQGL
CCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCC
MLQVIPGARHLWQIRECIYPELTEKTPQINLPSGLIVKEQQRLQFSLSVTGEQALVLLDM
EEEECCCHHHHHHHHHHHCHHHHCCCCCCCCCCCCEEECCCCEEEEEEECCCEEEEEEEC
TPYAWRASEQVKHLIRTKAFDVLEIDFVLVLAQKSLIES
CCCHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GLQFQCPTCGLALMQHQASQGFYCANKHHFDKNEAGYWIFTKPARQKPTGDSRQQVRAK
CCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
RFLLESGIFSPLVEKMAAMIAPHLKADDCLLDYECADGFYLRALASALLNLTNELNVQYS
HHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEC
GVADAENTIFAAAKAQTPATLCLSTSKVLPFADNCTDLITVVDKPLKGKECVRVLKEQGL
CCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCC
MLQVIPGARHLWQIRECIYPELTEKTPQINLPSGLIVKEQQRLQFSLSVTGEQALVLLDM
EEEECCCHHHHHHHHHHHCHHHHCCCCCCCCCCCCEEECCCCEEEEEEECCCEEEEEEEC
TPYAWRASEQVKHLIRTKAFDVLEIDFVLVLAQKSLIES
CCCHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7984109; 9097040; 9278503; 9440525 [H]