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The map label for this gene is yfcG [H]

Identifier: 117921307

GI number: 117921307

Start: 3425724

End: 3426392

Strand: Direct

Name: yfcG [H]

Synonym: Shewana3_2866

Alternate gene names: 117921307

Gene position: 3425724-3426392 (Clockwise)

Preceding gene: 117921306

Following gene: 117921308

Centisome position: 68.9

GC content: 48.88

Gene sequence:

>669_bases
ATGATTGATTTATATACCGCCGCGACCCCGAACGGTTTTAAAATTTCCATCGCGCTCGAAGAAATGGGTCTCGACTACCG
AGTGCATAAGCTAGATTTCAACACTAACGAACAGAAACAGCCTGAGTTTCTCGCCATTAACCCCAATGGCCGTATTCCGG
CCATTATCGACCGAGATAACGAGGACTTTGTGGTGTTCGAGTCCGGCGCAATTCTTCTGTATCTGGCGGAAAAAACCGGT
AAGTTCTTACCAGCCGATCCTAAAAAGCGCTCACAGGTCATTCAATGGCTCATGTTCCAAATGAGCGGTGTCGGCCCAAT
GATGGGTCAAGCTAACGTGTTTTACCGTTACTTCCCTGAAAAAATTCCCGCGGCCATTGAACGTTACCAAAAAGAAGGCC
GACGTTTGTTTGAGGTAATGAATACCCAGTTAGCCAAACATCAATATCTGGCCGGTGATGAATACACCATTGCCGATATC
GCGACTTGGCCTTGGGTTCGCATCCATGAATGGAGCGGCATCAATATGCAAGGACTCACTCACTTACAGCGTTGGTTAGA
CGAGCTAGCCCTGCGCCCCGCTTGCCAAAAAGGCATAGTGACCCCTCCGCCTTCGGTCTTGAGTGATGAAGAGCGCGCTA
AGCAAATCCAGAAGATGGTGACTAAGTAG

Upstream 100 bases:

>100_bases
CAGCGCCCTGCGATAGTGTCGCTTACCCCAAAAAACTGACAGCGATGCCCTATTGGGTACCCAAGTTAAGCATTAACCAG
TTAAGACTTAAGGGATAACT

Downstream 100 bases:

>100_bases
GTCATCACTTCCTAACGCATTCGTTTTCCCCATCAAGCCCCAACTCAGCATTGGGGCTTTTTTACTGCTAGCGATACGTA
AAACTGCTACACTCTGCGCC

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIDLYTAATPNGFKISIALEEMGLDYRVHKLDFNTNEQKQPEFLAINPNGRIPAIIDRDNEDFVVFESGAILLYLAEKTG
KFLPADPKKRSQVIQWLMFQMSGVGPMMGQANVFYRYFPEKIPAAIERYQKEGRRLFEVMNTQLAKHQYLAGDEYTIADI
ATWPWVRIHEWSGINMQGLTHLQRWLDELALRPACQKGIVTPPPSVLSDEERAKQIQKMVTK

Sequences:

>Translated_222_residues
MIDLYTAATPNGFKISIALEEMGLDYRVHKLDFNTNEQKQPEFLAINPNGRIPAIIDRDNEDFVVFESGAILLYLAEKTG
KFLPADPKKRSQVIQWLMFQMSGVGPMMGQANVFYRYFPEKIPAAIERYQKEGRRLFEVMNTQLAKHQYLAGDEYTIADI
ATWPWVRIHEWSGINMQGLTHLQRWLDELALRPACQKGIVTPPPSVLSDEERAKQIQKMVTK
>Mature_222_residues
MIDLYTAATPNGFKISIALEEMGLDYRVHKLDFNTNEQKQPEFLAINPNGRIPAIIDRDNEDFVVFESGAILLYLAEKTG
KFLPADPKKRSQVIQWLMFQMSGVGPMMGQANVFYRYFPEKIPAAIERYQKEGRRLFEVMNTQLAKHQYLAGDEYTIADI
ATWPWVRIHEWSGINMQGLTHLQRWLDELALRPACQKGIVTPPPSVLSDEERAKQIQKMVTK

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=204, Percent_Identity=47.0588235294118, Blast_Score=191, Evalue=3e-50,
Organism=Escherichia coli, GI87082195, Length=214, Percent_Identity=41.588785046729, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI87081789, Length=169, Percent_Identity=33.1360946745562, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324100, Length=232, Percent_Identity=36.6379310344828, Blast_Score=143, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28571670, Length=171, Percent_Identity=33.9181286549708, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI17864592, Length=190, Percent_Identity=33.1578947368421, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI85725204, Length=192, Percent_Identity=33.8541666666667, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737923, Length=192, Percent_Identity=33.8541666666667, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45549270, Length=188, Percent_Identity=31.3829787234043, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17933730, Length=190, Percent_Identity=30.5263157894737, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17864598, Length=167, Percent_Identity=34.1317365269461, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17864596, Length=188, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646251, Length=176, Percent_Identity=31.25, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864594, Length=188, Percent_Identity=29.7872340425532, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646249, Length=157, Percent_Identity=34.3949044585987, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221378983, Length=191, Percent_Identity=29.3193717277487, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646259, Length=191, Percent_Identity=29.3193717277487, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 25546; Mature: 25546

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYTAATPNGFKISIALEEMGLDYRVHKLDFNTNEQKQPEFLAINPNGRIPAIIDRDN
CEEEEECCCCCCEEEEEEEHHCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEEECCC
EDFVVFESGAILLYLAEKTGKFLPADPKKRSQVIQWLMFQMSGVGPMMGQANVFYRYFPE
CCEEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCH
KIPAAIERYQKEGRRLFEVMNTQLAKHQYLAGDEYTIADIATWPWVRIHEWSGINMQGLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHH
HLQRWLDELALRPACQKGIVTPPPSVLSDEERAKQIQKMVTK
HHHHHHHHHHCCHHHHCCCCCCCCHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIDLYTAATPNGFKISIALEEMGLDYRVHKLDFNTNEQKQPEFLAINPNGRIPAIIDRDN
CEEEEECCCCCCEEEEEEEHHCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEEECCC
EDFVVFESGAILLYLAEKTGKFLPADPKKRSQVIQWLMFQMSGVGPMMGQANVFYRYFPE
CCEEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCH
KIPAAIERYQKEGRRLFEVMNTQLAKHQYLAGDEYTIADIATWPWVRIHEWSGINMQGLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHH
HLQRWLDELALRPACQKGIVTPPPSVLSDEERAKQIQKMVTK
HHHHHHHHHHCCHHHHCCCCCCCCHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]