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The map label for this gene is sbcD [H]

Identifier: 117921053

GI number: 117921053

Start: 3118622

End: 3119824

Strand: Reverse

Name: sbcD [H]

Synonym: Shewana3_2612

Alternate gene names: 117921053

Gene position: 3119824-3118622 (Counterclockwise)

Preceding gene: 117921054

Following gene: 117921052

Centisome position: 62.75

GC content: 50.29

Gene sequence:

>1203_bases
ATGAGATTTATCCATACCTCGGACTGGCACATTGGCCGCCAGTTACACAATCAATCACTCTTAGAAGACCAAGCCTATGT
GCTTGATCAGATTGTGACATTGGCAGAGCAGCACTCTGTCGATGCGGTGATTATTGCCGGGGATATTTACGATAGGTCGA
TTCCACCTGCCAGCGCCGTGGCTTTGCTCGATGAGGTGCTTAATCGCCTTATCACAGAGTTAGGGTTACAAGTACTGCTG
ATTGCCGGTAACCACGACGGGCACGAACGCTTAGGCTTTGCGGCCAAACAAATGGCGGCAAGTGGTTTGCACATTATTGG
GCCACTGCAGGCTGATTTAACGCCGATCCGCTTAACCAGCCCAAGTGGCGATGCTTACTTTTATCTGCTGCCTTACGCCG
AACCTGCAACCGTGCGCCAAGTATTTGAGGCGGAAGCTAATGGGCTTAGCGTATCCAGTCATGAAGAGGCGATGACGCTA
CTGTTAGAACTAGTCCGCAGCCACGACAGCCAAGGGTTACCTAAAGTCGTGGTTAGTCATTGCTTTTTAGATGGCGGCAG
TGAGTCCGAGTCCGAGCGGCCATTGAATATTGGTGGTGCCGATAAAATCTCCCCACGGCTTTTTAGTGAGTTTGACTATG
TGGCCCTCGGCCACTTACACGGACCGCAATATAAAGGTTGCGAGCATGTACGTTATTCCGGCTCGATTTTGAAATATTCC
TTTAGCGAACAGCATCAACACAAGTCAGTCACTTTAGTGGACGTTGCAGCGCAAACTCCGGCGCAAATCCAACTCTTGCC
CTTAACGGCGCTGCGCGATGTGCGGATTATCGAAGGGGAATTGGCGCATTTATTAGATCTTGGGAAAACCGATGCTAAGC
GTGAGGATTATCTGATGGTCAGACTCCTCGATAAACACGCCATTTTAGATGCCATGGGCAAACTGCGCAGTGTCTATCCC
AATGTGCTGCATCTAGAACGCACAGGATTAATGGCGGGCGAGCAGGCCGTCACACTCAATCGTGACCATATCAAAAAAGG
CGAAATGGCCATGTTCCGTGATTTTTTCAGCCAAGTCTCTGGCGAGGCGCTGAGTGATGCGCAGCAAGCGGTTATGGATG
AGATTTTAACTAAGCTTCACAGGGATGAAGGGGATAGCGTTGGATCTACTCGCGTTAAAGCCAAAGGGGAGCAATCCGCA
TGA

Upstream 100 bases:

>100_bases
GACTGTGTTATTGCCAAGTGTTTGCACCGGAACTTCGCAAGTTAAACGGTAAGCGCCAGTGCGATAGAATCGGCTTAGTA
TCCATTAAGGTTTAACAACG

Downstream 100 bases:

>100_bases
AGCCACTCACGCTGTCAATGTCGGCCTTTGGCCCCTTTGCCTCGACTCAAACCATTGATTTTACCGAACTGGGGGATAAC
CCCTTATTCCTGATCAACGG

Product: exodeoxyribonuclease I subunit D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MRFIHTSDWHIGRQLHNQSLLEDQAYVLDQIVTLAEQHSVDAVIIAGDIYDRSIPPASAVALLDEVLNRLITELGLQVLL
IAGNHDGHERLGFAAKQMAASGLHIIGPLQADLTPIRLTSPSGDAYFYLLPYAEPATVRQVFEAEANGLSVSSHEEAMTL
LLELVRSHDSQGLPKVVVSHCFLDGGSESESERPLNIGGADKISPRLFSEFDYVALGHLHGPQYKGCEHVRYSGSILKYS
FSEQHQHKSVTLVDVAAQTPAQIQLLPLTALRDVRIIEGELAHLLDLGKTDAKREDYLMVRLLDKHAILDAMGKLRSVYP
NVLHLERTGLMAGEQAVTLNRDHIKKGEMAMFRDFFSQVSGEALSDAQQAVMDEILTKLHRDEGDSVGSTRVKAKGEQSA

Sequences:

>Translated_400_residues
MRFIHTSDWHIGRQLHNQSLLEDQAYVLDQIVTLAEQHSVDAVIIAGDIYDRSIPPASAVALLDEVLNRLITELGLQVLL
IAGNHDGHERLGFAAKQMAASGLHIIGPLQADLTPIRLTSPSGDAYFYLLPYAEPATVRQVFEAEANGLSVSSHEEAMTL
LLELVRSHDSQGLPKVVVSHCFLDGGSESESERPLNIGGADKISPRLFSEFDYVALGHLHGPQYKGCEHVRYSGSILKYS
FSEQHQHKSVTLVDVAAQTPAQIQLLPLTALRDVRIIEGELAHLLDLGKTDAKREDYLMVRLLDKHAILDAMGKLRSVYP
NVLHLERTGLMAGEQAVTLNRDHIKKGEMAMFRDFFSQVSGEALSDAQQAVMDEILTKLHRDEGDSVGSTRVKAKGEQSA
>Mature_400_residues
MRFIHTSDWHIGRQLHNQSLLEDQAYVLDQIVTLAEQHSVDAVIIAGDIYDRSIPPASAVALLDEVLNRLITELGLQVLL
IAGNHDGHERLGFAAKQMAASGLHIIGPLQADLTPIRLTSPSGDAYFYLLPYAEPATVRQVFEAEANGLSVSSHEEAMTL
LLELVRSHDSQGLPKVVVSHCFLDGGSESESERPLNIGGADKISPRLFSEFDYVALGHLHGPQYKGCEHVRYSGSILKYS
FSEQHQHKSVTLVDVAAQTPAQIQLLPLTALRDVRIIEGELAHLLDLGKTDAKREDYLMVRLLDKHAILDAMGKLRSVYP
NVLHLERTGLMAGEQAVTLNRDHIKKGEMAMFRDFFSQVSGEALSDAQQAVMDEILTKLHRDEGDSVGSTRVKAKGEQSA

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family [H]

Homologues:

Organism=Escherichia coli, GI1786598, Length=298, Percent_Identity=28.8590604026846, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 44044; Mature: 44044

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFIHTSDWHIGRQLHNQSLLEDQAYVLDQIVTLAEQHSVDAVIIAGDIYDRSIPPASAV
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHH
ALLDEVLNRLITELGLQVLLIAGNHDGHERLGFAAKQMAASGLHIIGPLQADLTPIRLTS
HHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEC
PSGDAYFYLLPYAEPATVRQVFEAEANGLSVSSHEEAMTLLLELVRSHDSQGLPKVVVSH
CCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
CFLDGGSESESERPLNIGGADKISPRLFSEFDYVALGHLHGPQYKGCEHVRYSGSILKYS
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCEEECCCEEEEE
FSEQHQHKSVTLVDVAAQTPAQIQLLPLTALRDVRIIEGELAHLLDLGKTDAKREDYLMV
CHHHHCCCCEEEEEECCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHCCCCCCCCCCEEEE
RLLDKHAILDAMGKLRSVYPNVLHLERTGLMAGEQAVTLNRDHIKKGEMAMFRDFFSQVS
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECHHHCCCCHHHHHHHHHHHHC
GEALSDAQQAVMDEILTKLHRDEGDSVGSTRVKAKGEQSA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MRFIHTSDWHIGRQLHNQSLLEDQAYVLDQIVTLAEQHSVDAVIIAGDIYDRSIPPASAV
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHH
ALLDEVLNRLITELGLQVLLIAGNHDGHERLGFAAKQMAASGLHIIGPLQADLTPIRLTS
HHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEC
PSGDAYFYLLPYAEPATVRQVFEAEANGLSVSSHEEAMTLLLELVRSHDSQGLPKVVVSH
CCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
CFLDGGSESESERPLNIGGADKISPRLFSEFDYVALGHLHGPQYKGCEHVRYSGSILKYS
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCEEECCCEEEEE
FSEQHQHKSVTLVDVAAQTPAQIQLLPLTALRDVRIIEGELAHLLDLGKTDAKREDYLMV
CHHHHCCCCEEEEEECCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHCCCCCCCCCCEEEE
RLLDKHAILDAMGKLRSVYPNVLHLERTGLMAGEQAVTLNRDHIKKGEMAMFRDFFSQVS
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECHHHCCCCHHHHHHHHHHHHC
GEALSDAQQAVMDEILTKLHRDEGDSVGSTRVKAKGEQSA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA