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The map label for this gene is ribA [H]

Identifier: 117921041

GI number: 117921041

Start: 3104099

End: 3104710

Strand: Reverse

Name: ribA [H]

Synonym: Shewana3_2600

Alternate gene names: 117921041

Gene position: 3104710-3104099 (Counterclockwise)

Preceding gene: 117921042

Following gene: 117921040

Centisome position: 62.44

GC content: 46.9

Gene sequence:

>612_bases
ATGTCGATAAAATATGTCGCGACGTCAAAATTACCCACTCCCTGGGGCGTTTTTGCCATGCACGGTTTTGAAGATACCGA
AACCAGTAAAGAGCATGTTGCCCTCACGTTTGGCACCCTAAGTAGCGATGCCCCCGTATTAGGCCGTATTCACTCTGAGT
GTCTTACGGGCGATGCCTTGTTTAGCTTACGCTGTGACTGTGGCTTCCAGCTGCAAACTGCGATGCAAAACATTGCCGAA
ACTGGCAGTGGATTTATCTTATATTTGCGTCAGGAAGGCCGCGGTATCGGTCTACTCAATAAGATCCGCGCCTATGAATT
GCAGGATAAAGGCGCCAATACGGTTGAGGCGAATGAGCAATTAGGTTTCCCGGCGGACATGCGTAAATACGATATGATCC
AACCTATGCTTGAACAAATTGGCGTGAAGCATGTACGCTTAATGACCAATAACCCTCGCAAAGTCAAAGCGATGAAAGAA
ATCGGCATCGAAGTGGTTGAGCGTGTTCCCCTGCAAGTCGGTAAAAACCGCTACAATGAAGCTTACTTAAAGACCAAATC
CACCGAACTTGGCCATATGATGTCTGAGTATCATTTTACGGATGAAGAGTAA

Upstream 100 bases:

>100_bases
CTTTAGAATAGGCGCTCAGTAGGCGAAGAGCCCAATCATCGTTTTGTTTATGGATGTTCCTTCCGTCTCATGGAATGAGA
GTAGTCGTTAAGGTTAAGTC

Downstream 100 bases:

>100_bases
TCTTTAACCAAAGCGATAACCGATTAGGCTTAGCAAATCAGGATCTGTTTGCATAAATTGAAGACCATTTTTAGCCGGTT
ACTCGTTAAATGCTTTTGCT

Product: GTP cyclohydrolase II

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSIKYVATSKLPTPWGVFAMHGFEDTETSKEHVALTFGTLSSDAPVLGRIHSECLTGDALFSLRCDCGFQLQTAMQNIAE
TGSGFILYLRQEGRGIGLLNKIRAYELQDKGANTVEANEQLGFPADMRKYDMIQPMLEQIGVKHVRLMTNNPRKVKAMKE
IGIEVVERVPLQVGKNRYNEAYLKTKSTELGHMMSEYHFTDEE

Sequences:

>Translated_203_residues
MSIKYVATSKLPTPWGVFAMHGFEDTETSKEHVALTFGTLSSDAPVLGRIHSECLTGDALFSLRCDCGFQLQTAMQNIAE
TGSGFILYLRQEGRGIGLLNKIRAYELQDKGANTVEANEQLGFPADMRKYDMIQPMLEQIGVKHVRLMTNNPRKVKAMKE
IGIEVVERVPLQVGKNRYNEAYLKTKSTELGHMMSEYHFTDEE
>Mature_202_residues
SIKYVATSKLPTPWGVFAMHGFEDTETSKEHVALTFGTLSSDAPVLGRIHSECLTGDALFSLRCDCGFQLQTAMQNIAET
GSGFILYLRQEGRGIGLLNKIRAYELQDKGANTVEANEQLGFPADMRKYDMIQPMLEQIGVKHVRLMTNNPRKVKAMKEI
GIEVVERVPLQVGKNRYNEAYLKTKSTELGHMMSEYHFTDEE

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1787533, Length=196, Percent_Identity=60.7142857142857, Blast_Score=257, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6319438, Length=195, Percent_Identity=39.4871794871795, Blast_Score=131, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 22839; Mature: 22707

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKYVATSKLPTPWGVFAMHGFEDTETSKEHVALTFGTLSSDAPVLGRIHSECLTGDAL
CCEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCE
FSLRCDCGFQLQTAMQNIAETGSGFILYLRQEGRGIGLLNKIRAYELQDKGANTVEANEQ
EEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHEEECCCCCCCCCCCCC
LGFPADMRKYDMIQPMLEQIGVKHVRLMTNNPRKVKAMKEIGIEVVERVPLQVGKNRYNE
CCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AYLKTKSTELGHMMSEYHFTDEE
HHEEECCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SIKYVATSKLPTPWGVFAMHGFEDTETSKEHVALTFGTLSSDAPVLGRIHSECLTGDAL
CEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCE
FSLRCDCGFQLQTAMQNIAETGSGFILYLRQEGRGIGLLNKIRAYELQDKGANTVEANEQ
EEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHEEECCCCCCCCCCCCC
LGFPADMRKYDMIQPMLEQIGVKHVRLMTNNPRKVKAMKEIGIEVVERVPLQVGKNRYNE
CCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AYLKTKSTELGHMMSEYHFTDEE
HHEEECCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA