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The map label for this gene is gph [H]

Identifier: 117921006

GI number: 117921006

Start: 3065931

End: 3066665

Strand: Reverse

Name: gph [H]

Synonym: Shewana3_2565

Alternate gene names: 117921006

Gene position: 3066665-3065931 (Counterclockwise)

Preceding gene: 117921007

Following gene: 117921004

Centisome position: 61.68

GC content: 48.84

Gene sequence:

>735_bases
GTGAGTCATTCAACCCAACGAAAATATGATTTAGTGATTTTTGATTGGGATGGCACGTTAATGGATTCCATCGGCAAGAT
TATTGTTTGCATTGAGAATATGGCAAGGGTGCTGGCGTTACCCGTGCCTTCAGAAGTGGATATTCGCAATGTGATTGGCT
TGTCGATGACGCAGGCGTTACAGGTATTATTTCCCGTCGGTTTGACTTCAGGGCAGTCGTGTATCGGATGTGCAAGCAGT
GCAACACAAGAAAATGCTGCTCAAGCGCTTGTAGGCACCGATGATTGCTATATGAAGATGCGCGCCGAGTTCAAGACGCA
GTATTTGCACCTTGATACCACGCCAACGCCGATTTTTAACCAAGCCCCCCAATTACTCGAATCATTATCAACGGCTGGGT
ATCAACTTGCTGTCGCGACGGGTAAGGCGAGAGCAGGCTTAGTGCGCGTGTGGGAGCAATCTGGCTTAGGTCACTACTTT
ATCGCTTCTCGCTGCGCCGATGAGGCGCAGAGTAAACCTCATCCTGAAATGATCTTAAGTTTGCTGCAGGAGTTAGGCGT
TCAGCCTGAACGAGCCTTGATGGTCGGAGACTCTTTGTTGGATTTGACCATGGCGGCGAATGCGGGGATTGATGCTGTGG
GCGTAACTTACGGCGCACATAATGAAGCAATGCTCCAGCAAGCCAATCCCATCGGCATAATTGATTCCCCTGAAAAACTC
TTGCTGCATTTATAG

Upstream 100 bases:

>100_bases
GCTTGATGATAATTTGCAGCAACTGCTAAGCAAGTTAAAGCGCGCTTAGTGTTTCTCTGCGCCTATTACCCACGTATAAC
CTGAGAGCGTGAAAGTGTCA

Downstream 100 bases:

>100_bases
TGATGGACTCATTAGTGCAGATTAATGAGCACTGAAAACTTGTACCGTGAGTAATCCAAATGCTTTTTGAATCATTTGAG
CAAGCGATATGGGCAAGTGT

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSHSTQRKYDLVIFDWDGTLMDSIGKIIVCIENMARVLALPVPSEVDIRNVIGLSMTQALQVLFPVGLTSGQSCIGCASS
ATQENAAQALVGTDDCYMKMRAEFKTQYLHLDTTPTPIFNQAPQLLESLSTAGYQLAVATGKARAGLVRVWEQSGLGHYF
IASRCADEAQSKPHPEMILSLLQELGVQPERALMVGDSLLDLTMAANAGIDAVGVTYGAHNEAMLQQANPIGIIDSPEKL
LLHL

Sequences:

>Translated_244_residues
MSHSTQRKYDLVIFDWDGTLMDSIGKIIVCIENMARVLALPVPSEVDIRNVIGLSMTQALQVLFPVGLTSGQSCIGCASS
ATQENAAQALVGTDDCYMKMRAEFKTQYLHLDTTPTPIFNQAPQLLESLSTAGYQLAVATGKARAGLVRVWEQSGLGHYF
IASRCADEAQSKPHPEMILSLLQELGVQPERALMVGDSLLDLTMAANAGIDAVGVTYGAHNEAMLQQANPIGIIDSPEKL
LLHL
>Mature_243_residues
SHSTQRKYDLVIFDWDGTLMDSIGKIIVCIENMARVLALPVPSEVDIRNVIGLSMTQALQVLFPVGLTSGQSCIGCASSA
TQENAAQALVGTDDCYMKMRAEFKTQYLHLDTTPTPIFNQAPQLLESLSTAGYQLAVATGKARAGLVRVWEQSGLGHYFI
ASRCADEAQSKPHPEMILSLLQELGVQPERALMVGDSLLDLTMAANAGIDAVGVTYGAHNEAMLQQANPIGIIDSPEKLL
LHL

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=231, Percent_Identity=26.8398268398268, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 26315; Mature: 26183

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSTQRKYDLVIFDWDGTLMDSIGKIIVCIENMARVLALPVPSEVDIRNVIGLSMTQAL
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHH
QVLFPVGLTSGQSCIGCASSATQENAAQALVGTDDCYMKMRAEFKTQYLHLDTTPTPIFN
HHHHHCCCCCCCCHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCEEEEEECCCCCCHHH
QAPQLLESLSTAGYQLAVATGKARAGLVRVWEQSGLGHYFIASRCADEAQSKPHPEMILS
HHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHH
LLQELGVQPERALMVGDSLLDLTMAANAGIDAVGVTYGAHNEAMLQQANPIGIIDSPEKL
HHHHHCCCCCCEEEECCHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCCCCCEECCCHHH
LLHL
HCCC
>Mature Secondary Structure 
SHSTQRKYDLVIFDWDGTLMDSIGKIIVCIENMARVLALPVPSEVDIRNVIGLSMTQAL
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHH
QVLFPVGLTSGQSCIGCASSATQENAAQALVGTDDCYMKMRAEFKTQYLHLDTTPTPIFN
HHHHHCCCCCCCCHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCEEEEEECCCCCCHHH
QAPQLLESLSTAGYQLAVATGKARAGLVRVWEQSGLGHYFIASRCADEAQSKPHPEMILS
HHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHH
LLQELGVQPERALMVGDSLLDLTMAANAGIDAVGVTYGAHNEAMLQQANPIGIIDSPEKL
HHHHHCCCCCCEEEECCHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCCCCCEECCCHHH
LLHL
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA