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The map label for this gene is bioA [H]

Identifier: 117920963

GI number: 117920963

Start: 3012218

End: 3013576

Strand: Direct

Name: bioA [H]

Synonym: Shewana3_2520

Alternate gene names: 117920963

Gene position: 3012218-3013576 (Clockwise)

Preceding gene: 117920958

Following gene: 117920964

Centisome position: 60.58

GC content: 54.23

Gene sequence:

>1359_bases
ATGCGCAATTTACTCGATTTGGATTTTGATAGCGCCCATATTTGGCATCCTTATACCTCCATGACCCGCGCACTTCCTGT
TTATGGGGTACACAGTGCACAAGGCTGCGAGCTGGAATTGGTCGATGGCCGTAAGCTTATCGATGGCACCAGCTCCTGGT
GGGCCTGCGTACATGGTTACGGACACCCAGCGATATTAACGGCGATGGAGCGGCAACTGCACCAACTTAGCCATGTGATG
TTTGGCGGCATTACCCACGAGCCCGCCATTACACTCTGCAAAAAACTGCTGGCGATGACCTGCGAGCCCCTCACTAAAGT
CTTTCTCTGCGACTCAGGCTCAATTGCCGTCGAAGTCGCCATCAAAATGGCGCTGCAATATTGGCAGGGGCAAGATTTGC
CTTTAGCGCAAAAGGCCCAAAAACAGCGCATTCTTACGGTGAAGAAGGGTTACCATGGCGATACTTTTGCCGCCATGAGT
GTCTGCGATCCCGAAGGTGGCATGCATACCATGTTTGGCGAAGCCGTCACGAAGCAGTGTTTTGTCGACGCGCCGCAAAC
ACCCTTCGGTGAGCCATTACGCCAAGATGATTTAGCGCCAATGCAACGTATTTTACGCGAGCAACATCCAGAGATTGCCG
CCGTGATTATCGAGCCGATTATGCAGGGCGCTGGGGGAATGCGATTCTACAGCAGCGAGTATTTACGCGGCCTGCGTGCC
CTGTGTGATGAATATAATGTGCTGCTTATTCTCGATGAAATCGCCACGGGTTTTGGGCGGACTGGTAAGTTATTTGCCTA
TGAGCATGCCGACATCACGCCCGACATTCTCTGCCTGGGCAAAGCGTTAACGGGCGGTTATATCAGTCTTGCCGCCACCT
TGTGCACGGATAACGTCGCCCAAGGCATTAGCCAATCGCCCGCAGGTGTCTTTATGCATGGCCCGACATTTATGGGCAAT
CCCCTCGCCTGCGCCGCCGCCTGCGCCAGCTTAGATTTAATCAATCAGCAGGAGTGGCCAGCACAGGTTGCCGCCATCGA
GCAGCAAATGCAGCGCGAGCTTGCCGATGCCATCGATATTCCCAGCGTGAAAGAGGTGCGCGTGCTCGGCGCGGTTGGCG
TGCTCGAAATGCACCAAGCGGTCAATACCGCCGCACTGCAACAGCAATTTGTCGACTTAGGCGTATGGGTGCGCCCCTTT
GCCAACCTGATTTATATTATGCCGCCCTATGTGATTAGTTCTTCACAGCTCACAAGGCTGACTCAGGCGATGAAGCAAGT
GGCGGCAACGATTGCACCGCCCCATGCCAATCAAAGCGAGGCACTGGTGACAGAGAGCATCACTATCAGCCACGGCTAA

Upstream 100 bases:

>100_bases
TTTTACCTTGGCTAGGATAACCTCAGCCCTTAAACTGTCAACGCCAACCAGTGATACAGGTTTACCACTGATTAATTTTC
AATCAACGCTGTGAGCTTTT

Downstream 100 bases:

>100_bases
TGTTGTTCAATCACAATGCACTCGTGATGCAAGCTCTGCTCTGCTCTGCTCTGCTCTGCTCTGCTCTGCTCTGCTCTGCT
CTGCTCTGCTCTGCTCTGTT

Product: aminotransferase

Products: NA

Alternate protein names: 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; Diaminopelargonic acid synthase [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MRNLLDLDFDSAHIWHPYTSMTRALPVYGVHSAQGCELELVDGRKLIDGTSSWWACVHGYGHPAILTAMERQLHQLSHVM
FGGITHEPAITLCKKLLAMTCEPLTKVFLCDSGSIAVEVAIKMALQYWQGQDLPLAQKAQKQRILTVKKGYHGDTFAAMS
VCDPEGGMHTMFGEAVTKQCFVDAPQTPFGEPLRQDDLAPMQRILREQHPEIAAVIIEPIMQGAGGMRFYSSEYLRGLRA
LCDEYNVLLILDEIATGFGRTGKLFAYEHADITPDILCLGKALTGGYISLAATLCTDNVAQGISQSPAGVFMHGPTFMGN
PLACAAACASLDLINQQEWPAQVAAIEQQMQRELADAIDIPSVKEVRVLGAVGVLEMHQAVNTAALQQQFVDLGVWVRPF
ANLIYIMPPYVISSSQLTRLTQAMKQVAATIAPPHANQSEALVTESITISHG

Sequences:

>Translated_452_residues
MRNLLDLDFDSAHIWHPYTSMTRALPVYGVHSAQGCELELVDGRKLIDGTSSWWACVHGYGHPAILTAMERQLHQLSHVM
FGGITHEPAITLCKKLLAMTCEPLTKVFLCDSGSIAVEVAIKMALQYWQGQDLPLAQKAQKQRILTVKKGYHGDTFAAMS
VCDPEGGMHTMFGEAVTKQCFVDAPQTPFGEPLRQDDLAPMQRILREQHPEIAAVIIEPIMQGAGGMRFYSSEYLRGLRA
LCDEYNVLLILDEIATGFGRTGKLFAYEHADITPDILCLGKALTGGYISLAATLCTDNVAQGISQSPAGVFMHGPTFMGN
PLACAAACASLDLINQQEWPAQVAAIEQQMQRELADAIDIPSVKEVRVLGAVGVLEMHQAVNTAALQQQFVDLGVWVRPF
ANLIYIMPPYVISSSQLTRLTQAMKQVAATIAPPHANQSEALVTESITISHG
>Mature_452_residues
MRNLLDLDFDSAHIWHPYTSMTRALPVYGVHSAQGCELELVDGRKLIDGTSSWWACVHGYGHPAILTAMERQLHQLSHVM
FGGITHEPAITLCKKLLAMTCEPLTKVFLCDSGSIAVEVAIKMALQYWQGQDLPLAQKAQKQRILTVKKGYHGDTFAAMS
VCDPEGGMHTMFGEAVTKQCFVDAPQTPFGEPLRQDDLAPMQRILREQHPEIAAVIIEPIMQGAGGMRFYSSEYLRGLRA
LCDEYNVLLILDEIATGFGRTGKLFAYEHADITPDILCLGKALTGGYISLAATLCTDNVAQGISQSPAGVFMHGPTFMGN
PLACAAACASLDLINQQEWPAQVAAIEQQMQRELADAIDIPSVKEVRVLGAVGVLEMHQAVNTAALQQQFVDLGVWVRPF
ANLIYIMPPYVISSSQLTRLTQAMKQVAATIAPPHANQSEALVTESITISHG

Specific function: Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=424, Percent_Identity=29.7169811320755, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI284507298, Length=322, Percent_Identity=30.1242236024845, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI13994255, Length=370, Percent_Identity=28.1081081081081, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI37574042, Length=415, Percent_Identity=22.4096385542169, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226442709, Length=415, Percent_Identity=22.4096385542169, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226442705, Length=421, Percent_Identity=21.8527315914489, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI24119277, Length=409, Percent_Identity=23.4718826405868, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI188536080, Length=288, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI38679950, Length=288, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI38679946, Length=288, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786991, Length=421, Percent_Identity=59.8574821852732, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI145693181, Length=431, Percent_Identity=31.322505800464, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789759, Length=345, Percent_Identity=32.7536231884058, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1789016, Length=422, Percent_Identity=30.0947867298578, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788044, Length=413, Percent_Identity=30.9927360774818, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1787560, Length=401, Percent_Identity=28.1795511221945, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786349, Length=323, Percent_Identity=31.2693498452012, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25144271, Length=400, Percent_Identity=27.25, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI25144274, Length=293, Percent_Identity=28.6689419795222, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32564660, Length=417, Percent_Identity=26.378896882494, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71992977, Length=398, Percent_Identity=22.8643216080402, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17541228, Length=397, Percent_Identity=22.9219143576826, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324386, Length=461, Percent_Identity=44.6854663774403, Blast_Score=400, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6323470, Length=427, Percent_Identity=29.7423887587822, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6324432, Length=323, Percent_Identity=30.3405572755418, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321456, Length=309, Percent_Identity=27.1844660194175, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357415, Length=415, Percent_Identity=29.3975903614458, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28574759, Length=323, Percent_Identity=27.2445820433437, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI161085790, Length=323, Percent_Identity=27.2445820433437, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21356575, Length=352, Percent_Identity=24.4318181818182, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281366494, Length=319, Percent_Identity=27.8996865203762, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24667139, Length=319, Percent_Identity=27.8996865203762, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24667143, Length=319, Percent_Identity=27.8996865203762, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR005815
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.62 [H]

Molecular weight: Translated: 49315; Mature: 49315

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLLDLDFDSAHIWHPYTSMTRALPVYGVHSAQGCELELVDGRKLIDGTSSWWACVHGY
CCCCCCCCCCCCEEECCHHHHHHCCCCEECCCCCCCEEEEECCCEEECCCCCHHHHHCCC
GHPAILTAMERQLHQLSHVMFGGITHEPAITLCKKLLAMTCEPLTKVFLCDSGSIAVEVA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHEEEEECCCCCHHHHH
IKMALQYWQGQDLPLAQKAQKQRILTVKKGYHGDTFAAMSVCDPEGGMHTMFGEAVTKQC
HHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
FVDAPQTPFGEPLRQDDLAPMQRILREQHPEIAAVIIEPIMQGAGGMRFYSSEYLRGLRA
HCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LCDEYNVLLILDEIATGFGRTGKLFAYEHADITPDILCLGKALTGGYISLAATLCTDNVA
HHCCCCEEEEEHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
QGISQSPAGVFMHGPTFMGNPLACAAACASLDLINQQEWPAQVAAIEQQMQRELADAIDI
HCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
PSVKEVRVLGAVGVLEMHQAVNTAALQQQFVDLGVWVRPFANLIYIMPPYVISSSQLTRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCEECCHHHHHH
TQAMKQVAATIAPPHANQSEALVTESITISHG
HHHHHHHHHHCCCCCCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MRNLLDLDFDSAHIWHPYTSMTRALPVYGVHSAQGCELELVDGRKLIDGTSSWWACVHGY
CCCCCCCCCCCCEEECCHHHHHHCCCCEECCCCCCCEEEEECCCEEECCCCCHHHHHCCC
GHPAILTAMERQLHQLSHVMFGGITHEPAITLCKKLLAMTCEPLTKVFLCDSGSIAVEVA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHEEEEECCCCCHHHHH
IKMALQYWQGQDLPLAQKAQKQRILTVKKGYHGDTFAAMSVCDPEGGMHTMFGEAVTKQC
HHHHHHHHCCCCCCHHHHHHHHHEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
FVDAPQTPFGEPLRQDDLAPMQRILREQHPEIAAVIIEPIMQGAGGMRFYSSEYLRGLRA
HCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LCDEYNVLLILDEIATGFGRTGKLFAYEHADITPDILCLGKALTGGYISLAATLCTDNVA
HHCCCCEEEEEHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
QGISQSPAGVFMHGPTFMGNPLACAAACASLDLINQQEWPAQVAAIEQQMQRELADAIDI
HCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
PSVKEVRVLGAVGVLEMHQAVNTAALQQQFVDLGVWVRPFANLIYIMPPYVISSSQLTRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCEECCHHHHHH
TQAMKQVAATIAPPHANQSEALVTESITISHG
HHHHHHHHHHCCCCCCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8890743 [H]