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The map label for this gene is rnd [H]

Identifier: 117920828

GI number: 117920828

Start: 2863731

End: 2864897

Strand: Reverse

Name: rnd [H]

Synonym: Shewana3_2385

Alternate gene names: 117920828

Gene position: 2864897-2863731 (Counterclockwise)

Preceding gene: 117920829

Following gene: 117920824

Centisome position: 57.62

GC content: 48.41

Gene sequence:

>1167_bases
ATGAGCCGGCTTTTGTTTTTATGGACGGTGCTTAACCCACAGGAACTGGAGAAGAATTTGTCAGTGTTTCAGTATGTGAG
CGACGAAGCGAGCCTCAATGCCCTCGTCGCTCAATATCAACAGAGTCCGCTGCTCGTGTTAGATACCGAGTTTGTGCGCA
CACGTACCTATTACGCTAAGCTTGGCCTCATTCAAGCCTATGATGGCAAAACCTTAGCCTTAATTGACCCGGTTGCGCTG
CCAGATCTCAGTGCATTTTGGTCTTTGCTGGATAATCCCAACATCATCAAACTGGTGCATTCGTGCAGCGAGGACTTAGA
AGTCTTCGCCCACTATGGTCAGCGTCAACCTACGCCTTTGTTCGATAGCCAAATCGCAGCCTCTTTATGTGGCATGGGCC
ATGGCCTAGGTTATGCCAAGTTAGTGGAAACCTGCTTAGGTGAAGTGATTGATAAAGGTGAGTCGCGCACCGACTGGATG
CGCCGTCCTTTGACTGAGGCGCAGCTGAGCTACGCCGCCAACGATGTGTTGTATCTGTATCAACTCTATCCGCAACTCGC
CGACAAGCTTAAGGCACAAGATCGCTTAGGCTGGTTGTATGAAGAAGGTGAACGGATGACAGAAGGGCGCTTAGCAACGC
CAGATATGGATACTGCGTACCTGAGAGTCAAAAACGCTTTTCAGCTCACCGAGCATCAATTGGCTTATCTTAAAGTATTG
GCTAAGTGGCGTTTAGAAAAAGCCTTAGCGCGGGATTTAGCCTTGGGCTTTGTGATTAAGGATCACGGCCTGATCGCGCT
AGCGAAAAAGCAGCCAAAGAGCATGGGCGATTTGCTCAAATTGAACGATTTGACCGAGCAAGAGAAACGCATTCACGGTA
AAGATATTTTACGGGTGATGCAGACTGCGGATTTAAGCAATCCACCAGAATTAGTGGATGTCTTAGCGCTAAAACCAGGT
TATAAATCGGCCTTTAAAAACATTAAAACCTGCTTATCTGAACTGTGCGAGCAGCATGCCATCCCGATGGAGATGCTGGG
CTCGAAACGTCATATTCATGAGTATTTACAATGGCGTTGGGATAAACAGCAGGGTGAGTTACCGACAGTCTTAAGTGGCT
GGCGTGGACAAATCGCCGCCGAATCGTTGGCAAAGCTTGACGTCTAA

Upstream 100 bases:

>100_bases
TGGTAGAATTTAGGGACGAGTTACCTAAAACCAACGTGGGTAAGATCTTGCGACGAGAACTTCGAGACGAAGTGAAGCGC
GCGTAAGATTGAAGCCGGCA

Downstream 100 bases:

>100_bases
TTTTAGGGCTGATTAATACATAATCTGCAGTAACATAGAGGTCTTGGCGTGTTGTTAAGACCTTTATCGCGTATATCAAG
GCTTAGCTTATTTCGCCTAA

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSRLLFLWTVLNPQELEKNLSVFQYVSDEASLNALVAQYQQSPLLVLDTEFVRTRTYYAKLGLIQAYDGKTLALIDPVAL
PDLSAFWSLLDNPNIIKLVHSCSEDLEVFAHYGQRQPTPLFDSQIAASLCGMGHGLGYAKLVETCLGEVIDKGESRTDWM
RRPLTEAQLSYAANDVLYLYQLYPQLADKLKAQDRLGWLYEEGERMTEGRLATPDMDTAYLRVKNAFQLTEHQLAYLKVL
AKWRLEKALARDLALGFVIKDHGLIALAKKQPKSMGDLLKLNDLTEQEKRIHGKDILRVMQTADLSNPPELVDVLALKPG
YKSAFKNIKTCLSELCEQHAIPMEMLGSKRHIHEYLQWRWDKQQGELPTVLSGWRGQIAAESLAKLDV

Sequences:

>Translated_388_residues
MSRLLFLWTVLNPQELEKNLSVFQYVSDEASLNALVAQYQQSPLLVLDTEFVRTRTYYAKLGLIQAYDGKTLALIDPVAL
PDLSAFWSLLDNPNIIKLVHSCSEDLEVFAHYGQRQPTPLFDSQIAASLCGMGHGLGYAKLVETCLGEVIDKGESRTDWM
RRPLTEAQLSYAANDVLYLYQLYPQLADKLKAQDRLGWLYEEGERMTEGRLATPDMDTAYLRVKNAFQLTEHQLAYLKVL
AKWRLEKALARDLALGFVIKDHGLIALAKKQPKSMGDLLKLNDLTEQEKRIHGKDILRVMQTADLSNPPELVDVLALKPG
YKSAFKNIKTCLSELCEQHAIPMEMLGSKRHIHEYLQWRWDKQQGELPTVLSGWRGQIAAESLAKLDV
>Mature_387_residues
SRLLFLWTVLNPQELEKNLSVFQYVSDEASLNALVAQYQQSPLLVLDTEFVRTRTYYAKLGLIQAYDGKTLALIDPVALP
DLSAFWSLLDNPNIIKLVHSCSEDLEVFAHYGQRQPTPLFDSQIAASLCGMGHGLGYAKLVETCLGEVIDKGESRTDWMR
RPLTEAQLSYAANDVLYLYQLYPQLADKLKAQDRLGWLYEEGERMTEGRLATPDMDTAYLRVKNAFQLTEHQLAYLKVLA
KWRLEKALARDLALGFVIKDHGLIALAKKQPKSMGDLLKLNDLTEQEKRIHGKDILRVMQTADLSNPPELVDVLALKPGY
KSAFKNIKTCLSELCEQHAIPMEMLGSKRHIHEYLQWRWDKQQGELPTVLSGWRGQIAAESLAKLDV

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=369, Percent_Identity=41.7344173441734, Blast_Score=280, Evalue=9e-77,
Organism=Caenorhabditis elegans, GI17531757, Length=258, Percent_Identity=28.6821705426357, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161078302, Length=256, Percent_Identity=24.609375, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 44034; Mature: 43903

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLLFLWTVLNPQELEKNLSVFQYVSDEASLNALVAQYQQSPLLVLDTEFVRTRTYYAK
CCCEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHH
LGLIQAYDGKTLALIDPVALPDLSAFWSLLDNPNIIKLVHSCSEDLEVFAHYGQRQPTPL
HCEEEECCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
FDSQIAASLCGMGHGLGYAKLVETCLGEVIDKGESRTDWMRRPLTEAQLSYAANDVLYLY
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHH
QLYPQLADKLKAQDRLGWLYEEGERMTEGRLATPDMDTAYLRVKNAFQLTEHQLAYLKVL
HHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AKWRLEKALARDLALGFVIKDHGLIALAKKQPKSMGDLLKLNDLTEQEKRIHGKDILRVM
HHHHHHHHHHHHHHHHEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTADLSNPPELVDVLALKPGYKSAFKNIKTCLSELCEQHAIPMEMLGSKRHIHEYLQWRW
HHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHC
DKQQGELPTVLSGWRGQIAAESLAKLDV
CCCCCCCCHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SRLLFLWTVLNPQELEKNLSVFQYVSDEASLNALVAQYQQSPLLVLDTEFVRTRTYYAK
CCEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHH
LGLIQAYDGKTLALIDPVALPDLSAFWSLLDNPNIIKLVHSCSEDLEVFAHYGQRQPTPL
HCEEEECCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
FDSQIAASLCGMGHGLGYAKLVETCLGEVIDKGESRTDWMRRPLTEAQLSYAANDVLYLY
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHH
QLYPQLADKLKAQDRLGWLYEEGERMTEGRLATPDMDTAYLRVKNAFQLTEHQLAYLKVL
HHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AKWRLEKALARDLALGFVIKDHGLIALAKKQPKSMGDLLKLNDLTEQEKRIHGKDILRVM
HHHHHHHHHHHHHHHHEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTADLSNPPELVDVLALKPGYKSAFKNIKTCLSELCEQHAIPMEMLGSKRHIHEYLQWRW
HHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHC
DKQQGELPTVLSGWRGQIAAESLAKLDV
CCCCCCCCHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]