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The map label for this gene is sdaA [H]

Identifier: 117920738

GI number: 117920738

Start: 2758463

End: 2759839

Strand: Direct

Name: sdaA [H]

Synonym: Shewana3_2295

Alternate gene names: 117920738

Gene position: 2758463-2759839 (Clockwise)

Preceding gene: 117920737

Following gene: 117920740

Centisome position: 55.48

GC content: 50.11

Gene sequence:

>1377_bases
ATGATTAGCGTATTCGATATGTTCAAGATCGGCATTGGCCCTTCGAGTTCACACACTGTTGGCCCAATGAAAGCGGGCAA
AATTTTTATGCAGCACCTTGCTGATTCGGGCCAGATTGCCCAAGTGGATGAATTAAGAGCAGAACTGTTTGGCTCACTCG
GTCAAACGGGTAAAGGCCACGGCACGGGGAAAGCCGTTATTTTAGGCTTAATGGGTGAAGATCCAGAAACCGTCGACACC
GACAGCATCGATGGCATTCTTGAGCAAGTGTCGAAAAACGAGACCCTCACCCTCAGCTGCGGCAAAGTAGTTAAGTTTAC
CCGTGAAGACGGCATTACCTACCATAGACGCAAAACGCTCCCCGCCCATGCCAACGCCATGACACTGTATGCCTACAGCA
AAGGCGAATGTATTTTTGAGCGCACTTACTACTCTGTCGGCGGTGGATTTATCTTAGACGAAGATGAAATCCATCAACGC
AACGCCTCACCAGCATCACAAATTGAATCTGCACCTTACGATTTTAATAGCAGCGCCCAATTACTGGATTTATGTACTGA
GCATGGCCTGAGCATATCTTCCCTAATGATGGCCAACGAGCTTAGCCTCGCCAGCGAAGAAGAAGTCAAAGCAAAACTGT
GGAATATCTGGCAAACCATGAAAACCTGTATCGAACGGGGTTATCAGAAGGAAGGTATTCTGCCTGGCGGTTTAAAGCTG
CGTCGCCGCGCACCTGCACTCTATCGTCGTCTCAAAGCTGAAGGCCGTAACAACGTCGATCCGTTAACCGCAATGGATTG
GGTCGATTTATTCGCCCTCTCGGTGAACGAGCAAAACGCTGCCGGCGATCGCGTTGTCACCGCACCGACAAACGGCGCTG
CGGGCATTATCCCTGCCGTGCTGTGTTACTACGATACCTTCGTGCAAGAAGTCGATATCGATGTTTGCGCCCGTTACCTG
TTAACCGCTGCTGCTATTGGTATTTTGTACAAGAAAAATGCCTCGATTTCGGGCGCAGAAGTCGGCTGTCAGGGCGAAGT
TGGCGTAGCCTGCTCAATGGCAGCCGGCGCATTGACCGAAATCATGGGCGGCACAGTCGAACATGTTGAAAACGCGGCTG
AAATTGGCATGGAACATAACCTAGGCTTGACCTGCGACCCAGTAGGCGGCCTAGTACAAGTTCCTTGTATTGAACGTAAT
GCGATGGGTGCAATCAAGGCGATTAACGCATCACGCATGGCGCTGCGCGGCGACGGTAACCACAAGGTATCACTGGATAA
AGTGATTAAAACCATGATGGATACAGGTAAAGATATGCGCAGTAAATACAAAGAAACCGCCAAAGGTGGCCTCGCGGTGA
ACATTGTTGAGTGTTAA

Upstream 100 bases:

>100_bases
CAGAGTTTACGACATAAAAACCAGCGTATTGGCGCGGTAACTGCAAAGATCTTCCACGCACAGACTAAAATAAAAATCGA
GACACAACAGGACTTCAATC

Downstream 100 bases:

>100_bases
TCCACTCATGCTGATAATCGACTTACCGATTTAACACTGTCATGCCGCGCTTAACCGTTCAAACCGAAACGATTAAGCGC
GGCATATGTTTATCTGAAAA

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKIFMQHLADSGQIAQVDELRAELFGSLGQTGKGHGTGKAVILGLMGEDPETVDT
DSIDGILEQVSKNETLTLSCGKVVKFTREDGITYHRRKTLPAHANAMTLYAYSKGECIFERTYYSVGGGFILDEDEIHQR
NASPASQIESAPYDFNSSAQLLDLCTEHGLSISSLMMANELSLASEEEVKAKLWNIWQTMKTCIERGYQKEGILPGGLKL
RRRAPALYRRLKAEGRNNVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYYDTFVQEVDIDVCARYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAIKAINASRMALRGDGNHKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC

Sequences:

>Translated_458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKIFMQHLADSGQIAQVDELRAELFGSLGQTGKGHGTGKAVILGLMGEDPETVDT
DSIDGILEQVSKNETLTLSCGKVVKFTREDGITYHRRKTLPAHANAMTLYAYSKGECIFERTYYSVGGGFILDEDEIHQR
NASPASQIESAPYDFNSSAQLLDLCTEHGLSISSLMMANELSLASEEEVKAKLWNIWQTMKTCIERGYQKEGILPGGLKL
RRRAPALYRRLKAEGRNNVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYYDTFVQEVDIDVCARYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAIKAINASRMALRGDGNHKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC
>Mature_458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGKIFMQHLADSGQIAQVDELRAELFGSLGQTGKGHGTGKAVILGLMGEDPETVDT
DSIDGILEQVSKNETLTLSCGKVVKFTREDGITYHRRKTLPAHANAMTLYAYSKGECIFERTYYSVGGGFILDEDEIHQR
NASPASQIESAPYDFNSSAQLLDLCTEHGLSISSLMMANELSLASEEEVKAKLWNIWQTMKTCIERGYQKEGILPGGLKL
RRRAPALYRRLKAEGRNNVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYYDTFVQEVDIDVCARYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAIKAINASRMALRGDGNHKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=459, Percent_Identity=56.6448801742919, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1789161, Length=459, Percent_Identity=55.3376906318083, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI48994925, Length=458, Percent_Identity=54.8034934497817, Blast_Score=496, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49241; Mature: 49241

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGKIFMQHLADSGQIAQVDELRAELFGSLGQTGKGH
CCCHHEEHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
GTGKAVILGLMGEDPETVDTDSIDGILEQVSKNETLTLSCGKVVKFTREDGITYHRRKTL
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHEEEHHHCCCEEEECCCC
PAHANAMTLYAYSKGECIFERTYYSVGGGFILDEDEIHQRNASPASQIESAPYDFNSSAQ
CCCCCEEEEEEECCCCEEEEEHHHCCCCCEEECCHHHHHCCCCCHHHHCCCCCCCCCCHH
LLDLCTEHGLSISSLMMANELSLASEEEVKAKLWNIWQTMKTCIERGYQKEGILPGGLKL
HHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
RRRAPALYRRLKAEGRNNVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEECCCCCCCCCEEEECCCCCCHHHHHHH
LCYYDTFVQEVDIDVCARYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAIKAINASRMALRGDGN
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCHHHCCCCCCEEEECCCC
HKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC
CEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGKIFMQHLADSGQIAQVDELRAELFGSLGQTGKGH
CCCHHEEHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
GTGKAVILGLMGEDPETVDTDSIDGILEQVSKNETLTLSCGKVVKFTREDGITYHRRKTL
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHEEEHHHCCCEEEECCCC
PAHANAMTLYAYSKGECIFERTYYSVGGGFILDEDEIHQRNASPASQIESAPYDFNSSAQ
CCCCCEEEEEEECCCCEEEEEHHHCCCCCEEECCHHHHHCCCCCHHHHCCCCCCCCCCHH
LLDLCTEHGLSISSLMMANELSLASEEEVKAKLWNIWQTMKTCIERGYQKEGILPGGLKL
HHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
RRRAPALYRRLKAEGRNNVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEECCCCCCCCCEEEECCCCCCHHHHHHH
LCYYDTFVQEVDIDVCARYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAGALTE
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAIKAINASRMALRGDGN
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCHHHCCCCCCEEEECCCC
HKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC
CEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]