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The map label for this gene is ychM [C]

Identifier: 117920707

GI number: 117920707

Start: 2724842

End: 2726599

Strand: Reverse

Name: ychM [C]

Synonym: Shewana3_2264

Alternate gene names: 117920707

Gene position: 2726599-2724842 (Counterclockwise)

Preceding gene: 117920708

Following gene: 117920704

Centisome position: 54.84

GC content: 50.68

Gene sequence:

>1758_bases
GTGAAGTTTCCCAGTTTAGTATCGTTAATGCCCGGTTTGGCGCAGATGCTGCAGTATGAGAAGCAATGGCTCAGGGATGA
TGTGAGGGCGGGATTATCTGTGGCGGCGGTTGCTTTACCCGTTGCTATCGCCTACGCCCAATTGACCGGGGTTAATGCCG
CCGTGGGTTTATACTCCTGCGTGCTGCCCATGTTGGTATATGCACTGTTTGGCACATCTAGACAATTGATTGTTGGTCCC
GATGCCGCCACCTGCGCCGTGATTGCCGCAGTGGTGACGCCGCTTGCAGCAGGCGATAGCATGAAGCACTGGCAATTGGT
GATGACCATGACGGCGATGACCGGCTTTTGGTGCTTAATCGCCAGCCGTTTTCGCCTTGGGGTATTAGCTGACTTTCTCT
CCAAACCTATCCTAATGGGGCTACTCAATGGTGTGGCGATCACCATTATCGTTGGCCAATTCTCGAAAATTTTTGGTTTT
ACCTTCGATGAACGTTATTTGATTGAGCGTTTATCCGGTGCGCCTTCCTATTTAACTCGAACCCACTGGCCTACCTTGCT
GATGGGTGTGGTGACCTTAGCAACCTATGCCTTAGTGAAACGATATCGTCCACAGTGGCCAGCCTCTATGTGTGCGATGG
CTATGGCGGCGTTTTTAGTCTGGGCCTTTAACTTAACCAGCTTAGATATCAATGTGGTGGGTGAGGTGAGCGCTGGCTTG
CCATCGTTCCAAGCGCCTGTGTTCGATATCGGTATTGCCCGTGAACTGGTGGTGCCCGCACTCAACTTAGCCATGGTGAG
CTTTGTGAGCATGATGCTGACGGCGCGCAGTTTTGCGGCAAAAAATGGCTACGATATCGATGCGGATAAAGAGTTTCGCG
CCCTAGGGATTGCCAATATCGCTTCGGCTTTATCTCAGGGTTTTGCCGTCAGTGGCGCCGATTCGCGCACTGCGGTTAAC
GATGCAAACGGCGGTAAGAGTCAGTTGGTGTCCATCATCGCAGCGGTATTAATTGCATTAGTCGCGCTATTTTTTACCGC
ACCACTGAAATATATCCCCAGTTCCGCGCTCGGCGTGGTATTGGTGATTGCTTCGATTTCCTTGATTGATTTAAAGGCGT
TGTGGAACCTGCGCGTGCGGGATCGCTCCGCCTTTTTACTCGCCTGTACAACGTTGTTTTCGGTGCTGTTTATTGGGGTT
ATTCCTGGCATTACCTTGGCGGTACTGCTGGGCTTATTCCAATTTTTAGCAACAGTGATGCGCCCAACCGACCAAGTCCT
CGGGCTGGACCAAAAAGGGGTGATTCGCAGTGTGGATGATTCTGGCAAAGCCAAATCTGTACCAGGCGTGTTTATCTACC
GTTTCAACTCGCCGTTAACCTACTTCAACGCCACTTACTTTAAGCGCCGCCTACTGGAGAAGTTTATCCGCGAGCCAGAG
CCCGTTGATTGCATTATCATCGATGCTGTGCCGTGTTTTACTCACTTAGATTTGAGTGTGATGGCCATGCTTGCGGATTT
ACATCAACTACTGAAGAAGCGCGGCATACGCTTAGTTTTAGCCGGTCGTAAACGACAGATGCTCGGCTGGTTTGAACAAG
CGGGAATGCAGTCCGGTGAAGGCGGTATCTTGATCAGACCCGATTTATATCTGGCGCTGAAAATGAACCAAAGTTACAAA
CAAGCGTTAGCCGAGGGGCAGGCGCCAGTGATCAAAAAAGATCCCGAGGATGATGTGTTATTGCACAGTCATTTATAG

Upstream 100 bases:

>100_bases
TTTTTAGGTAACGGCCTTTTGGGATCCCATTGAGGCTTAGTTATACTTAGCCACCGCAAGTTAGTGATTAACTTGGGAGT
GAGTATATGGAGGTTACTGC

Downstream 100 bases:

>100_bases
AAGCAAACCTAATAAAAAAGCGCGATATTGTTCGCGCTTTTTTATGGCTCATTCAACACCCTTAGAAAACATCGGTGAGC
TTAAATTAACTTAGTCATTT

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MKFPSLVSLMPGLAQMLQYEKQWLRDDVRAGLSVAAVALPVAIAYAQLTGVNAAVGLYSCVLPMLVYALFGTSRQLIVGP
DAATCAVIAAVVTPLAAGDSMKHWQLVMTMTAMTGFWCLIASRFRLGVLADFLSKPILMGLLNGVAITIIVGQFSKIFGF
TFDERYLIERLSGAPSYLTRTHWPTLLMGVVTLATYALVKRYRPQWPASMCAMAMAAFLVWAFNLTSLDINVVGEVSAGL
PSFQAPVFDIGIARELVVPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFRALGIANIASALSQGFAVSGADSRTAVN
DANGGKSQLVSIIAAVLIALVALFFTAPLKYIPSSALGVVLVIASISLIDLKALWNLRVRDRSAFLLACTTLFSVLFIGV
IPGITLAVLLGLFQFLATVMRPTDQVLGLDQKGVIRSVDDSGKAKSVPGVFIYRFNSPLTYFNATYFKRRLLEKFIREPE
PVDCIIIDAVPCFTHLDLSVMAMLADLHQLLKKRGIRLVLAGRKRQMLGWFEQAGMQSGEGGILIRPDLYLALKMNQSYK
QALAEGQAPVIKKDPEDDVLLHSHL

Sequences:

>Translated_585_residues
MKFPSLVSLMPGLAQMLQYEKQWLRDDVRAGLSVAAVALPVAIAYAQLTGVNAAVGLYSCVLPMLVYALFGTSRQLIVGP
DAATCAVIAAVVTPLAAGDSMKHWQLVMTMTAMTGFWCLIASRFRLGVLADFLSKPILMGLLNGVAITIIVGQFSKIFGF
TFDERYLIERLSGAPSYLTRTHWPTLLMGVVTLATYALVKRYRPQWPASMCAMAMAAFLVWAFNLTSLDINVVGEVSAGL
PSFQAPVFDIGIARELVVPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFRALGIANIASALSQGFAVSGADSRTAVN
DANGGKSQLVSIIAAVLIALVALFFTAPLKYIPSSALGVVLVIASISLIDLKALWNLRVRDRSAFLLACTTLFSVLFIGV
IPGITLAVLLGLFQFLATVMRPTDQVLGLDQKGVIRSVDDSGKAKSVPGVFIYRFNSPLTYFNATYFKRRLLEKFIREPE
PVDCIIIDAVPCFTHLDLSVMAMLADLHQLLKKRGIRLVLAGRKRQMLGWFEQAGMQSGEGGILIRPDLYLALKMNQSYK
QALAEGQAPVIKKDPEDDVLLHSHL
>Mature_585_residues
MKFPSLVSLMPGLAQMLQYEKQWLRDDVRAGLSVAAVALPVAIAYAQLTGVNAAVGLYSCVLPMLVYALFGTSRQLIVGP
DAATCAVIAAVVTPLAAGDSMKHWQLVMTMTAMTGFWCLIASRFRLGVLADFLSKPILMGLLNGVAITIIVGQFSKIFGF
TFDERYLIERLSGAPSYLTRTHWPTLLMGVVTLATYALVKRYRPQWPASMCAMAMAAFLVWAFNLTSLDINVVGEVSAGL
PSFQAPVFDIGIARELVVPALNLAMVSFVSMMLTARSFAAKNGYDIDADKEFRALGIANIASALSQGFAVSGADSRTAVN
DANGGKSQLVSIIAAVLIALVALFFTAPLKYIPSSALGVVLVIASISLIDLKALWNLRVRDRSAFLLACTTLFSVLFIGV
IPGITLAVLLGLFQFLATVMRPTDQVLGLDQKGVIRSVDDSGKAKSVPGVFIYRFNSPLTYFNATYFKRRLLEKFIREPE
PVDCIIIDAVPCFTHLDLSVMAMLADLHQLLKKRGIRLVLAGRKRQMLGWFEQAGMQSGEGGILIRPDLYLALKMNQSYK
QALAEGQAPVIKKDPEDDVLLHSHL

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=496, Percent_Identity=26.6129032258064, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI39752683, Length=496, Percent_Identity=26.6129032258064, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI262206105, Length=566, Percent_Identity=27.0318021201413, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI262206075, Length=566, Percent_Identity=27.0318021201413, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI262206069, Length=566, Percent_Identity=27.0318021201413, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI262206063, Length=566, Percent_Identity=27.0318021201413, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI269784651, Length=492, Percent_Identity=26.0162601626016, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI94721257, Length=499, Percent_Identity=25.8517034068136, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI94721259, Length=499, Percent_Identity=25.8517034068136, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI94721255, Length=499, Percent_Identity=25.8517034068136, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI94721253, Length=499, Percent_Identity=25.8517034068136, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI4557535, Length=519, Percent_Identity=26.0115606936416, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI4505697, Length=511, Percent_Identity=26.614481409002, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI45827802, Length=434, Percent_Identity=26.7281105990783, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI16418413, Length=518, Percent_Identity=23.3590733590734, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI217272867, Length=518, Percent_Identity=23.3590733590734, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI100913030, Length=529, Percent_Identity=24.3856332703214, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI16418457, Length=520, Percent_Identity=25.3846153846154, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI301601599, Length=520, Percent_Identity=25.3846153846154, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI47131207, Length=521, Percent_Identity=25.5278310940499, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI20336272, Length=521, Percent_Identity=25.5278310940499, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI20336282, Length=579, Percent_Identity=22.4525043177893, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI16306483, Length=579, Percent_Identity=22.4525043177893, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI301601602, Length=292, Percent_Identity=25.3424657534247, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI65506789, Length=414, Percent_Identity=25.6038647342995, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI45827804, Length=258, Percent_Identity=24.8062015503876, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081859, Length=435, Percent_Identity=23.448275862069, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI86565215, Length=481, Percent_Identity=24.5322245322245, Blast_Score=135, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI86564196, Length=618, Percent_Identity=23.462783171521, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17551690, Length=570, Percent_Identity=24.2105263157895, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17566848, Length=568, Percent_Identity=24.2957746478873, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17562578, Length=615, Percent_Identity=22.2764227642276, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193203292, Length=507, Percent_Identity=22.6824457593688, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI86564876, Length=386, Percent_Identity=22.020725388601, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI86565209, Length=241, Percent_Identity=23.6514522821577, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI86565211, Length=241, Percent_Identity=23.6514522821577, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6325260, Length=579, Percent_Identity=22.4525043177893, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323121, Length=465, Percent_Identity=23.8709677419355, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6319771, Length=467, Percent_Identity=23.7687366167024, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21358229, Length=461, Percent_Identity=26.6811279826464, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI85815873, Length=457, Percent_Identity=26.6958424507659, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24649801, Length=566, Percent_Identity=24.5583038869258, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24666186, Length=544, Percent_Identity=23.8970588235294, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI19922482, Length=430, Percent_Identity=27.2093023255814, Blast_Score=122, Evalue=9e-28,
Organism=Drosophila melanogaster, GI21355087, Length=441, Percent_Identity=24.4897959183673, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24647160, Length=441, Percent_Identity=24.4897959183673, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24651449, Length=579, Percent_Identity=22.1070811744387, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21358633, Length=458, Percent_Identity=23.1441048034935, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24663084, Length=441, Percent_Identity=24.4897959183673, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357695, Length=441, Percent_Identity=24.4897959183673, Blast_Score=93, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 63516; Mature: 63516

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEECCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCEEECCC
>Mature Secondary Structure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CCEEECCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]