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The map label for this gene is pgl [H]

Identifier: 117920594

GI number: 117920594

Start: 2575790

End: 2576488

Strand: Reverse

Name: pgl [H]

Synonym: Shewana3_2150

Alternate gene names: 117920594

Gene position: 2576488-2575790 (Counterclockwise)

Preceding gene: 117920595

Following gene: 117920593

Centisome position: 51.82

GC content: 51.07

Gene sequence:

>699_bases
ATGATTAAAGAAACCGTATTTAAATCCTTTGATACACCCGCAGCGCTCGAGCAACAGTTGGCGAATAAGATCGCCAGTCA
GTTGCAAGAGGCTGTGGATGCCCGCGGTAAGGCAAGCTTAGTCGTCTCCGGCGGCTCAACACCGCTGAAACTGTTTGAGC
TCCTCAGCATGAAATCCATCGATTGGAGTGATGTTTATGTCACGCTCGCCGATGAGCGCTGGGTAGATGTGGAAGACAGT
GCATCGAATGAGCGGTTAGTGCGTGAACATTTACTGCAAAACCGCGCGGCCAATGCCAAGTTCCGCGGATTAAAGAATAT
GTTTTCCACCGCCGAAGCGGGCGCCGATATGACCGCCGAGTCGCTGTCTAATTTCCCGCGTCCCTTCGATGTAGTGGTGC
TCGGTATGGGCAATGATGGTCACACTTGCTCATGGTTCCCTTGCAGCGCCGAGTTAAATGATGCCTTGAGCACTCAAGCC
CTGTGTGTGGCAACCAATCCCACCACGGCGCCCCATGGCCGGATCACATTATCTAAGAATGCGATCCTCAATAGCAGACA
GATTTATCTGCATTTGGTCGGGGAACAGAAATTATCCGTATATCGTCAAGCCTTAGAAAATGATGATGTTAATGCTATGC
CCATCAGAGCCGTATTAGCGCAGCGTAAAACGCCCGTTGACGTGTTCTGGAGCGCTTAA

Upstream 100 bases:

>100_bases
CGAGAAACCGAAACCTTATCCTGCGGGCACTTGGGGACCTGTTGCGTCGGTCGCGCTGATCACCAAAGACGGCCGTTCGT
GGGATGAATAGGGGGCTTTT

Downstream 100 bases:

>100_bases
GGAGTCACTCTCATGCACTCAGTCGTTCAATCTGTTACCGACAGAATTATTGCCCGTAGCAAAGCATCTCGTGAAGCGTA
TTTAGCCGCGTTAAATGATG

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MIKETVFKSFDTPAALEQQLANKIASQLQEAVDARGKASLVVSGGSTPLKLFELLSMKSIDWSDVYVTLADERWVDVEDS
ASNERLVREHLLQNRAANAKFRGLKNMFSTAEAGADMTAESLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELNDALSTQA
LCVATNPTTAPHGRITLSKNAILNSRQIYLHLVGEQKLSVYRQALENDDVNAMPIRAVLAQRKTPVDVFWSA

Sequences:

>Translated_232_residues
MIKETVFKSFDTPAALEQQLANKIASQLQEAVDARGKASLVVSGGSTPLKLFELLSMKSIDWSDVYVTLADERWVDVEDS
ASNERLVREHLLQNRAANAKFRGLKNMFSTAEAGADMTAESLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELNDALSTQA
LCVATNPTTAPHGRITLSKNAILNSRQIYLHLVGEQKLSVYRQALENDDVNAMPIRAVLAQRKTPVDVFWSA
>Mature_232_residues
MIKETVFKSFDTPAALEQQLANKIASQLQEAVDARGKASLVVSGGSTPLKLFELLSMKSIDWSDVYVTLADERWVDVEDS
ASNERLVREHLLQNRAANAKFRGLKNMFSTAEAGADMTAESLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELNDALSTQA
LCVATNPTTAPHGRITLSKNAILNSRQIYLHLVGEQKLSVYRQALENDDVNAMPIRAVLAQRKTPVDVFWSA

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=192, Percent_Identity=31.7708333333333, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115533060, Length=203, Percent_Identity=29.064039408867, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115533058, Length=203, Percent_Identity=29.064039408867, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321957, Length=227, Percent_Identity=27.7533039647577, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641119, Length=210, Percent_Identity=29.0476190476191, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25485; Mature: 25485

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKETVFKSFDTPAALEQQLANKIASQLQEAVDARGKASLVVSGGSTPLKLFELLSMKSI
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCC
DWSDVYVTLADERWVDVEDSASNERLVREHLLQNRAANAKFRGLKNMFSTAEAGADMTAE
CCCEEEEEEECCEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHH
SLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELNDALSTQALCVATNPTTAPHGRITLSKN
HHHCCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHCCCEEEEECCCCCCCCCEEEEECC
AILNSRQIYLHLVGEQKLSVYRQALENDDVNAMPIRAVLAQRKTPVDVFWSA
HHCCCCEEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MIKETVFKSFDTPAALEQQLANKIASQLQEAVDARGKASLVVSGGSTPLKLFELLSMKSI
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCC
DWSDVYVTLADERWVDVEDSASNERLVREHLLQNRAANAKFRGLKNMFSTAEAGADMTAE
CCCEEEEEEECCEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHH
SLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELNDALSTQALCVATNPTTAPHGRITLSKN
HHHCCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHCCCEEEEECCCCCCCCCEEEEECC
AILNSRQIYLHLVGEQKLSVYRQALENDDVNAMPIRAVLAQRKTPVDVFWSA
HHCCCCEEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA