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The map label for this gene is aspC [H]

Identifier: 117920565

GI number: 117920565

Start: 2544569

End: 2545762

Strand: Reverse

Name: aspC [H]

Synonym: Shewana3_2121

Alternate gene names: 117920565

Gene position: 2545762-2544569 (Counterclockwise)

Preceding gene: 117920566

Following gene: 117920563

Centisome position: 51.2

GC content: 47.82

Gene sequence:

>1194_bases
ATGATTTTCTCTCAGGTAGTACTCGCACCCGCTGATCCCATCCTTGGTTTAACCGATACCTTCAAGGCCGATCCACGCCA
AGATAAAGTGAACCTCGGTGTTGGCATTTATAAGGATGAAGCAGGGCAGACTCCAGTATTACAGTCAGTGAAGAAAGCAG
AAGCCCTATTGCTTGAGCAAGAGAAGACCAAGAACTATTTAGGTATTGAAGGGGTTCAAACCTATAACCGCGTGGTACAA
GAGCTATTATTTGGCGAGGGCAGTACGCTTGTGACGTCAGGCCGTGCCGCGACCGCTCAGGCGCCAGGTGGTACTGGTGC
ACTGCGTATTGCCGCCGAGTTTCTACTGCGCAACACGCCATCGCGCACTGTGTGGGTCAGTAACCCAACTTGGGCGAACC
ATCAGAATATTTTTGAAACTGCAGGTTTAACGGTTAAAGAATACGGTTACTACAATGCCAGTGCCCACGATATCGATTTC
GATGGCATGATGACAGATCTCGCCAATGCACAGGCGGGTGACATTGTTCTACTGCACGGTTGCTGCCATAACCCAACGGG
TATTGATTTGACCTTAGCCCAATGGGAATTGGTTGCTAACCTGTGTGCAGACAAACAGTTAGTGCCATTGTTTGACTTTG
CTTACCAAGGTTTTGGTGCTGGGATTGAAGAAGATGCCGCAGGCCTACGTTTAGTGGCTGCAAAAGTACCTGAGTTGTTA
GTGGCTAACTCTTTCTCTAAAAACTTTGGTCTTTATAACGAGCGTATCGGCGCTGTGACTGTAGTGGCACAAAATGCCGA
TGAAGCGGTGCGTGCCTTCAGCCAAGTGAAACGTACTATTCGCGCCAATTACTCAAACCCACCAGCACACGGTGCGTTAA
TTGTTAGCACCATTTTAAGCGATGCGGCATTAAAAGCACTTTGGGTACAAGAGTTGACTGAAATGCGTGAACGTATCGCC
CAGATGCGTACTCTGTTCGTCCAAAGCTTAAAGGATGAAGGCGTCACCCAGGACTTTAGCTTTATTTCCCGCCAAAACGG
TATGTTTAGCTTCTCTGGCTTAAACAAAGAGCAGGTTGCACGCTTAAAAGACGAGTTTGGTATTTATATCGTCGGCTCAG
GCCGCATTAGTGTTGCCGGTATGACCAAAACCAATATGCCTGTGATCTGTAAAGCGATTGCCCAAGTTCTTTAA

Upstream 100 bases:

>100_bases
ATTTCCTTAAGATGCGGCAATAGGCGCTATTCCCCCTCTTAAGACAGTGGTATAAATAAGCCGAATTTCCCCTACACGTG
AACATTTAGGATAAGTAGTC

Downstream 100 bases:

>100_bases
CTTAGTTCTTTAACTTAGCTCTTTAATTTAGCTCTTTGATTTAGTCCTCTAATATCAGAAGAGGGCTCACTAAAAAGGAC
AGCCTAGGCTGTCCTTTTTG

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MIFSQVVLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLQSVKKAEALLLEQEKTKNYLGIEGVQTYNRVVQ
ELLFGEGSTLVTSGRAATAQAPGGTGALRIAAEFLLRNTPSRTVWVSNPTWANHQNIFETAGLTVKEYGYYNASAHDIDF
DGMMTDLANAQAGDIVLLHGCCHNPTGIDLTLAQWELVANLCADKQLVPLFDFAYQGFGAGIEEDAAGLRLVAAKVPELL
VANSFSKNFGLYNERIGAVTVVAQNADEAVRAFSQVKRTIRANYSNPPAHGALIVSTILSDAALKALWVQELTEMRERIA
QMRTLFVQSLKDEGVTQDFSFISRQNGMFSFSGLNKEQVARLKDEFGIYIVGSGRISVAGMTKTNMPVICKAIAQVL

Sequences:

>Translated_397_residues
MIFSQVVLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLQSVKKAEALLLEQEKTKNYLGIEGVQTYNRVVQ
ELLFGEGSTLVTSGRAATAQAPGGTGALRIAAEFLLRNTPSRTVWVSNPTWANHQNIFETAGLTVKEYGYYNASAHDIDF
DGMMTDLANAQAGDIVLLHGCCHNPTGIDLTLAQWELVANLCADKQLVPLFDFAYQGFGAGIEEDAAGLRLVAAKVPELL
VANSFSKNFGLYNERIGAVTVVAQNADEAVRAFSQVKRTIRANYSNPPAHGALIVSTILSDAALKALWVQELTEMRERIA
QMRTLFVQSLKDEGVTQDFSFISRQNGMFSFSGLNKEQVARLKDEFGIYIVGSGRISVAGMTKTNMPVICKAIAQVL
>Mature_397_residues
MIFSQVVLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLQSVKKAEALLLEQEKTKNYLGIEGVQTYNRVVQ
ELLFGEGSTLVTSGRAATAQAPGGTGALRIAAEFLLRNTPSRTVWVSNPTWANHQNIFETAGLTVKEYGYYNASAHDIDF
DGMMTDLANAQAGDIVLLHGCCHNPTGIDLTLAQWELVANLCADKQLVPLFDFAYQGFGAGIEEDAAGLRLVAAKVPELL
VANSFSKNFGLYNERIGAVTVVAQNADEAVRAFSQVKRTIRANYSNPPAHGALIVSTILSDAALKALWVQELTEMRERIA
QMRTLFVQSLKDEGVTQDFSFISRQNGMFSFSGLNKEQVARLKDEFGIYIVGSGRISVAGMTKTNMPVICKAIAQVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=44.4444444444444, Blast_Score=337, Evalue=8e-93,
Organism=Homo sapiens, GI4504067, Length=404, Percent_Identity=39.3564356435644, Blast_Score=293, Evalue=2e-79,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=27.9373368146214, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=62.8787878787879, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=45.5919395465995, Blast_Score=369, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=42.0253164556962, Blast_Score=350, Evalue=7e-97,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=42.5316455696203, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17569539, Length=399, Percent_Identity=37.34335839599, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=40.2843601895735, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=29.7157622739018, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17550384, Length=267, Percent_Identity=35.5805243445693, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=38.0246913580247, Blast_Score=286, Evalue=4e-78,
Organism=Saccharomyces cerevisiae, GI6322743, Length=438, Percent_Identity=34.0182648401827, Blast_Score=253, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24580972, Length=397, Percent_Identity=42.3173803526448, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24580970, Length=397, Percent_Identity=42.3173803526448, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI19920542, Length=392, Percent_Identity=42.0918367346939, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI19922362, Length=395, Percent_Identity=41.7721518987342, Blast_Score=310, Evalue=9e-85,
Organism=Drosophila melanogaster, GI24654046, Length=395, Percent_Identity=41.7721518987342, Blast_Score=310, Evalue=9e-85,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43084; Mature: 43084

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSQVVLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLQSVKKAEALLLEQ
CCCCCEEECCCCCCCCCCCCCCCCCCCCCEEECEEEEECCCCCCHHHHHHHHHHHHHHHH
EKTKNYLGIEGVQTYNRVVQELLFGEGSTLVTSGRAATAQAPGGTGALRIAAEFLLRNTP
HHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
SRTVWVSNPTWANHQNIFETAGLTVKEYGYYNASAHDIDFDGMMTDLANAQAGDIVLLHG
CCEEEECCCCCCCCCHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEC
CCHNPTGIDLTLAQWELVANLCADKQLVPLFDFAYQGFGAGIEEDAAGLRLVAAKVPELL
CCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEHHHHCCHHH
VANSFSKNFGLYNERIGAVTVVAQNADEAVRAFSQVKRTIRANYSNPPAHGALIVSTILS
HHCCCHHCCCCHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DAALKALWVQELTEMRERIAQMRTLFVQSLKDEGVTQDFSFISRQNGMFSFSGLNKEQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCHHHHH
RLKDEFGIYIVGSGRISVAGMTKTNMPVICKAIAQVL
HHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MIFSQVVLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLQSVKKAEALLLEQ
CCCCCEEECCCCCCCCCCCCCCCCCCCCCEEECEEEEECCCCCCHHHHHHHHHHHHHHHH
EKTKNYLGIEGVQTYNRVVQELLFGEGSTLVTSGRAATAQAPGGTGALRIAAEFLLRNTP
HHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
SRTVWVSNPTWANHQNIFETAGLTVKEYGYYNASAHDIDFDGMMTDLANAQAGDIVLLHG
CCEEEECCCCCCCCCHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEC
CCHNPTGIDLTLAQWELVANLCADKQLVPLFDFAYQGFGAGIEEDAAGLRLVAAKVPELL
CCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEHHHHCCHHH
VANSFSKNFGLYNERIGAVTVVAQNADEAVRAFSQVKRTIRANYSNPPAHGALIVSTILS
HHCCCHHCCCCHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DAALKALWVQELTEMRERIAQMRTLFVQSLKDEGVTQDFSFISRQNGMFSFSGLNKEQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCHHHHH
RLKDEFGIYIVGSGRISVAGMTKTNMPVICKAIAQVL
HHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]