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The map label for this gene is dgoR [H]

Identifier: 117920512

GI number: 117920512

Start: 2475530

End: 2476246

Strand: Direct

Name: dgoR [H]

Synonym: Shewana3_2068

Alternate gene names: 117920512

Gene position: 2475530-2476246 (Clockwise)

Preceding gene: 117920511

Following gene: 117920514

Centisome position: 49.79

GC content: 47.7

Gene sequence:

>717_bases
ATGGCAAATCAGGCAAATAACCGTCCGCAGAATATCCATAACTGGGTGGCAAGCGAATTAGGTTCTCGCATTGTGGGCGG
CTTTTATGCGCCAGGTGAATATATCCCTAACGAAAATGCTATCTGTGAAGAGCTGGAAGTGTCACGCACCTCCTTAAGGG
AAGCCTTTAAGGTACTCACGGCAAAGGGGCTTATTGAATCTCGCCCTAAACTTGGCACTCGTATTCGTGAGCGTCGCCAC
TGGAATATGTTTGATCCGGTGATCTTAAACTGGTTTTCCCAATCTAAGCCTTCGCCCGAGTTTTACACTTCTCTCTATGA
AATCCGTGAAGTGTTTGAACCCGCAGCGGCGGAACTGGCGGCGAAAAAACGCACCCCTGAGCAGCTTGAGGTGATTGCGG
CAGCCTATGCAAAGATGGAAGCGGCCGAATTAGGTACGGATGAAGTCTATACCTCGGATATCGATTTCCACATGGCGATT
TTAGATGCGACCAATAACGAGTTTATGGTATCCCTCGGCGTGTCGATCCAATCTGCGCTGCTCGAAATCTTTAGACTCAG
TAGCACAATTCAGGATGACTTTATCCAATCACTCCCAGGGCATAAGGCCATTTATACTGCGATTGCCGCAGGGGACAGTG
AAGGCGCGAAAGCCGAAATGAATAAATTACTCTCGACGTCTCAAGATACTGTGCATAAAAATATCGAGCGAAAATAA

Upstream 100 bases:

>100_bases
TTATCAGGAAAGGTAGTATCATAACATTTGTTTATCAGCGTTAAGCACCTTATCCAGTTGATTGGATTGAGCACAGAGAT
AGAGAGTTAAAGAGGGCACT

Downstream 100 bases:

>100_bases
CAAAGTATCTAGCATAAGTAACGAGTTACTTATCTTTAACGTCCCTCGATCAATAAAAAAGGTGAACTTAGGTTCACCTT
TTTTGTTTTACTGCGAGCAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MANQANNRPQNIHNWVASELGSRIVGGFYAPGEYIPNENAICEELEVSRTSLREAFKVLTAKGLIESRPKLGTRIRERRH
WNMFDPVILNWFSQSKPSPEFYTSLYEIREVFEPAAAELAAKKRTPEQLEVIAAAYAKMEAAELGTDEVYTSDIDFHMAI
LDATNNEFMVSLGVSIQSALLEIFRLSSTIQDDFIQSLPGHKAIYTAIAAGDSEGAKAEMNKLLSTSQDTVHKNIERK

Sequences:

>Translated_238_residues
MANQANNRPQNIHNWVASELGSRIVGGFYAPGEYIPNENAICEELEVSRTSLREAFKVLTAKGLIESRPKLGTRIRERRH
WNMFDPVILNWFSQSKPSPEFYTSLYEIREVFEPAAAELAAKKRTPEQLEVIAAAYAKMEAAELGTDEVYTSDIDFHMAI
LDATNNEFMVSLGVSIQSALLEIFRLSSTIQDDFIQSLPGHKAIYTAIAAGDSEGAKAEMNKLLSTSQDTVHKNIERK
>Mature_237_residues
ANQANNRPQNIHNWVASELGSRIVGGFYAPGEYIPNENAICEELEVSRTSLREAFKVLTAKGLIESRPKLGTRIRERRHW
NMFDPVILNWFSQSKPSPEFYTSLYEIREVFEPAAAELAAKKRTPEQLEVIAAAYAKMEAAELGTDEVYTSDIDFHMAIL
DATNNEFMVSLGVSIQSALLEIFRLSSTIQDDFIQSLPGHKAIYTAIAAGDSEGAKAEMNKLLSTSQDTVHKNIERK

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=209, Percent_Identity=32.0574162679426, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI48994961, Length=219, Percent_Identity=31.0502283105023, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789353, Length=168, Percent_Identity=32.1428571428571, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1790780, Length=231, Percent_Identity=29.8701298701299, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790032, Length=239, Percent_Identity=29.2887029288703, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786303, Length=216, Percent_Identity=28.7037037037037, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26641; Mature: 26510

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANQANNRPQNIHNWVASELGSRIVGGFYAPGEYIPNENAICEELEVSRTSLREAFKVLT
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AKGLIESRPKLGTRIRERRHWNMFDPVILNWFSQSKPSPEFYTSLYEIREVFEPAAAELA
HHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AKKRTPEQLEVIAAAYAKMEAAELGTDEVYTSDIDFHMAILDATNNEFMVSLGVSIQSAL
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHEECCCCEEEEEEECCCCCEEEEECHHHHHHH
LEIFRLSSTIQDDFIQSLPGHKAIYTAIAAGDSEGAKAEMNKLLSTSQDTVHKNIERK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHCCCC
>Mature Secondary Structure 
ANQANNRPQNIHNWVASELGSRIVGGFYAPGEYIPNENAICEELEVSRTSLREAFKVLT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AKGLIESRPKLGTRIRERRHWNMFDPVILNWFSQSKPSPEFYTSLYEIREVFEPAAAELA
HHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AKKRTPEQLEVIAAAYAKMEAAELGTDEVYTSDIDFHMAILDATNNEFMVSLGVSIQSAL
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHEECCCCEEEEEEECCCCCEEEEECHHHHHHH
LEIFRLSSTIQDDFIQSLPGHKAIYTAIAAGDSEGAKAEMNKLLSTSQDTVHKNIERK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]