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The map label for this gene is zraR [H]

Identifier: 117920470

GI number: 117920470

Start: 2419269

End: 2420771

Strand: Direct

Name: zraR [H]

Synonym: Shewana3_2025

Alternate gene names: 117920470

Gene position: 2419269-2420771 (Clockwise)

Preceding gene: 117920469

Following gene: 117920471

Centisome position: 48.66

GC content: 39.32

Gene sequence:

>1503_bases
ATGCATACACTACTAACTTGGCTTGGCAATCGTGATTTAGAAAATATGCAGCAAGATAAAATTGCTGCAATTACAGCCAT
TGCGCTTAAAGCACAACCACACTTTGATAAAATTGTTATTCTATCCAATGATAAAGAAGAGACGTGGTCTAGGTTTGAAG
CATTTTTGAAAAAAAGCATGGCGGTAAATGGTAGGCCTTATAATGACATTAAAATAGTCAAAGCACATATTGAAAGCCCC
ATTGACTACCACACGATAGCTAAAGAAACTGAAAAATGGATTACAAAACTCAGTGAAGAAGCCGACACACTATCAATAAA
TCTTACATCTGGTACGCCAGCCATGACGGCGTTATCAGTTTTGATTGGCAAAGGTAAGGCTAACACAAAGTTTCTTCAGG
CTACACCAACCAACGAATTACTTCATGTTGAGATCCCCATTGATTTTGGCAGTGAGTATCTTCGCTCAGCATCAAAAAAT
ATTGCCTATTTAGCTACCTCTCACCCCAAACTAGAGTCTGCGTTTTCTGTCATAACAGCTAAGTCACTCGTTATGCAAGA
TACAGTAAGTAAAGCTAAACGCGTAGCTGCATCTGAAGTGCCTGTTTTAATTTTAGGTGAAACAGGAACGGGTAAAGAAG
TAATGGCTCAAGCGATTCATCGCGCAAGTTTACGAGCAGGCCAACCGCTAAAAATAGTCAATTGCGGGGCATTAGCACCA
AACCTTGTCGACTCTACATTATTTGGCCATAAAAAGGGGGCCTTCACTGGTGCAGACAAGGATTACCCAGGTTTGTTTGA
GCAAGCCAATAATGGCACTCTATTTCTAGATGAAGTGGGTGAATTACCTCTGGATGTTCAAGTTAAACTGCTTCGAGCAT
TACAGCAGGGAGAGGTGACACGATTGGGTGATACTAAAACCATCAATGTGGATGTGCGTGTCATTGCTGCGACTCACCAA
GATTTAAATAAGCTCGTTGCTAATGGAAAATTCAGGGAAGATTTGTTTTATCGCTTGGCAGTTGGTGTGATTCGAATCCC
GTCGTTAAGGGAACGTCAGGAAGATATCCCCCTCATAGTTGGTCAGCTTGTAGATCAAATCAATCATTCTGCATCTAAAC
ACCCACAATATATAAGTAAGAAAATTTCCGAAAAAGGAATTAAATTTTTATCCAGTCAGTACTGGCCAGGCAATATTCGA
GATCTATGGAGCACACTCAACCGTGCTTTTTTATGGTCAGATACTTCAATAATGGATGAATATGAATTATCTCAAGCGAT
GTTAACAAGATCACAAGTAGTAGAAGATGTACCAATTTCCTTAACATTTAATGATAAAGTTGATATAGTGCAACTAACTG
ATAATTTGCAAAAAAATTATGTTGTAGCCGCTCTTAAAGCCAGTGGGAACGTTAAAAAACATGCTACTCAAATGCTCGGT
TTAAAAGATCACCAGACGCTCACCAATTGGATGAAACGTTTAGGAATAGCAACAGAGAAATAA

Upstream 100 bases:

>100_bases
AAAAACCCCGTCACAGCCATTTGTGTCAGTATTCATTTGATGTAAATTTTCTTATTTTAGGTATTATTATTTACACTAAT
GGTCTAAATGAACAAATCCA

Downstream 100 bases:

>100_bases
TCGCTAAAAAAATATTGGCACCAAAGTTGCCCATTAGGGAAGAAGGAATACTGCGGAATGAAGCAATCTATGAATTTTGA
GTTTTTACGAAAAAATTGGC

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MHTLLTWLGNRDLENMQQDKIAAITAIALKAQPHFDKIVILSNDKEETWSRFEAFLKKSMAVNGRPYNDIKIVKAHIESP
IDYHTIAKETEKWITKLSEEADTLSINLTSGTPAMTALSVLIGKGKANTKFLQATPTNELLHVEIPIDFGSEYLRSASKN
IAYLATSHPKLESAFSVITAKSLVMQDTVSKAKRVAASEVPVLILGETGTGKEVMAQAIHRASLRAGQPLKIVNCGALAP
NLVDSTLFGHKKGAFTGADKDYPGLFEQANNGTLFLDEVGELPLDVQVKLLRALQQGEVTRLGDTKTINVDVRVIAATHQ
DLNKLVANGKFREDLFYRLAVGVIRIPSLRERQEDIPLIVGQLVDQINHSASKHPQYISKKISEKGIKFLSSQYWPGNIR
DLWSTLNRAFLWSDTSIMDEYELSQAMLTRSQVVEDVPISLTFNDKVDIVQLTDNLQKNYVVAALKASGNVKKHATQMLG
LKDHQTLTNWMKRLGIATEK

Sequences:

>Translated_500_residues
MHTLLTWLGNRDLENMQQDKIAAITAIALKAQPHFDKIVILSNDKEETWSRFEAFLKKSMAVNGRPYNDIKIVKAHIESP
IDYHTIAKETEKWITKLSEEADTLSINLTSGTPAMTALSVLIGKGKANTKFLQATPTNELLHVEIPIDFGSEYLRSASKN
IAYLATSHPKLESAFSVITAKSLVMQDTVSKAKRVAASEVPVLILGETGTGKEVMAQAIHRASLRAGQPLKIVNCGALAP
NLVDSTLFGHKKGAFTGADKDYPGLFEQANNGTLFLDEVGELPLDVQVKLLRALQQGEVTRLGDTKTINVDVRVIAATHQ
DLNKLVANGKFREDLFYRLAVGVIRIPSLRERQEDIPLIVGQLVDQINHSASKHPQYISKKISEKGIKFLSSQYWPGNIR
DLWSTLNRAFLWSDTSIMDEYELSQAMLTRSQVVEDVPISLTFNDKVDIVQLTDNLQKNYVVAALKASGNVKKHATQMLG
LKDHQTLTNWMKRLGIATEK
>Mature_500_residues
MHTLLTWLGNRDLENMQQDKIAAITAIALKAQPHFDKIVILSNDKEETWSRFEAFLKKSMAVNGRPYNDIKIVKAHIESP
IDYHTIAKETEKWITKLSEEADTLSINLTSGTPAMTALSVLIGKGKANTKFLQATPTNELLHVEIPIDFGSEYLRSASKN
IAYLATSHPKLESAFSVITAKSLVMQDTVSKAKRVAASEVPVLILGETGTGKEVMAQAIHRASLRAGQPLKIVNCGALAP
NLVDSTLFGHKKGAFTGADKDYPGLFEQANNGTLFLDEVGELPLDVQVKLLRALQQGEVTRLGDTKTINVDVRVIAATHQ
DLNKLVANGKFREDLFYRLAVGVIRIPSLRERQEDIPLIVGQLVDQINHSASKHPQYISKKISEKGIKFLSSQYWPGNIR
DLWSTLNRAFLWSDTSIMDEYELSQAMLTRSQVVEDVPISLTFNDKVDIVQLTDNLQKNYVVAALKASGNVKKHATQMLG
LKDHQTLTNWMKRLGIATEK

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=368, Percent_Identity=39.4021739130435, Blast_Score=238, Evalue=9e-64,
Organism=Escherichia coli, GI1788905, Length=304, Percent_Identity=41.4473684210526, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI1789087, Length=345, Percent_Identity=40.5797101449275, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI87082117, Length=334, Percent_Identity=39.8203592814371, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1788550, Length=267, Percent_Identity=44.9438202247191, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI87082152, Length=305, Percent_Identity=42.2950819672131, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1790299, Length=230, Percent_Identity=46.5217391304348, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789233, Length=239, Percent_Identity=43.5146443514644, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI87081872, Length=305, Percent_Identity=37.3770491803279, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1786524, Length=227, Percent_Identity=44.9339207048458, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1787583, Length=255, Percent_Identity=40.3921568627451, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789828, Length=496, Percent_Identity=27.2177419354839, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI87081858, Length=311, Percent_Identity=31.5112540192926, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 55504; Mature: 55504

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLLTWLGNRDLENMQQDKIAAITAIALKAQPHFDKIVILSNDKEETWSRFEAFLKKSM
CCCHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHH
AVNGRPYNDIKIVKAHIESPIDYHTIAKETEKWITKLSEEADTLSINLTSGTPAMTALSV
HCCCCCCCCHHEEEEHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
LIGKGKANTKFLQATPTNELLHVEIPIDFGSEYLRSASKNIAYLATSHPKLESAFSVITA
HHCCCCCCCEEEEECCCCCEEEEEEECCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
KSLVMQDTVSKAKRVAASEVPVLILGETGTGKEVMAQAIHRASLRAGQPLKIVNCGALAP
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCC
NLVDSTLFGHKKGAFTGADKDYPGLFEQANNGTLFLDEVGELPLDVQVKLLRALQQGEVT
HHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEE
RLGDTKTINVDVRVIAATHQDLNKLVANGKFREDLFYRLAVGVIRIPSLRERQEDIPLIV
ECCCCEEEEEEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHH
GQLVDQINHSASKHPQYISKKISEKGIKFLSSQYWPGNIRDLWSTLNRAFLWSDTSIMDE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCCCHHHH
YELSQAMLTRSQVVEDVPISLTFNDKVDIVQLTDNLQKNYVVAALKASGNVKKHATQMLG
HHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHC
LKDHQTLTNWMKRLGIATEK
CCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHTLLTWLGNRDLENMQQDKIAAITAIALKAQPHFDKIVILSNDKEETWSRFEAFLKKSM
CCCHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHH
AVNGRPYNDIKIVKAHIESPIDYHTIAKETEKWITKLSEEADTLSINLTSGTPAMTALSV
HCCCCCCCCHHEEEEHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
LIGKGKANTKFLQATPTNELLHVEIPIDFGSEYLRSASKNIAYLATSHPKLESAFSVITA
HHCCCCCCCEEEEECCCCCEEEEEEECCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
KSLVMQDTVSKAKRVAASEVPVLILGETGTGKEVMAQAIHRASLRAGQPLKIVNCGALAP
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCC
NLVDSTLFGHKKGAFTGADKDYPGLFEQANNGTLFLDEVGELPLDVQVKLLRALQQGEVT
HHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEE
RLGDTKTINVDVRVIAATHQDLNKLVANGKFREDLFYRLAVGVIRIPSLRERQEDIPLIV
ECCCCEEEEEEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHH
GQLVDQINHSASKHPQYISKKISEKGIKFLSSQYWPGNIRDLWSTLNRAFLWSDTSIMDE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCCCHHHH
YELSQAMLTRSQVVEDVPISLTFNDKVDIVQLTDNLQKNYVVAALKASGNVKKHATQMLG
HHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHC
LKDHQTLTNWMKRLGIATEK
CCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]