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The map label for this gene is luxO [H]

Identifier: 117920461

GI number: 117920461

Start: 2405533

End: 2407014

Strand: Direct

Name: luxO [H]

Synonym: Shewana3_2016

Alternate gene names: 117920461

Gene position: 2405533-2407014 (Clockwise)

Preceding gene: 117920460

Following gene: 117920463

Centisome position: 48.38

GC content: 48.92

Gene sequence:

>1482_bases
ATGAATTATTCAGCATTATTGGTTGAAGACAGTATGTCACTCGGTGCGCTCTATACGGAGTATTTGCGCGCGGAGGATAT
TAATGTAACCCATGTGCATTACGGCGCGGATGCCCTAAAGGAATTATCGAACTGGCAGCCCGATCTGTTAATTCTCGATA
TTAAGCTGCCGGATATGTCGGGTCTCGACATCCTTAAGCAAGTGCAGCAGAGTCATCCCCATATCAGCACCATTATGATC
ACCGCCCACGGCAGCATCGATATTGCCATCGATGCGATGCGCTCAGGGGCGTTCGACTTCTTAGTTAAACCCTTCGATGC
CAAGCGACTATCGATAACGGTGCGTAATGCCCTTAAACAAAAACAATTACTCGAGCTTGTGACTCAGTATGAAAACAGCT
TACCAAAAGGTCATTACCAAGGGTTTATCGGCGACTCGCTGGCAATGCAGAGCGTGTACAAAACCATTGATTGTGTCGCC
AACAGTAAGGCGTCGGTATTTATTATGGGGGAGAGTGGTACGGGTAAAGAAGTCTGCGCTCAAGCCATTCACCAAGTCGG
TAATCGCGCCGACAAACCCTTTATCGCCTTAAACTGCGCATCAATCCCGAAAGAACTGATTGAAAGCGAAATTTTTGGCC
ACTGCAAAGGGGCATTCACCGGCGCCCATAACAATCGGGATGGCGCCGCGACCCGAGCCGACGGCGGCACCTTGTTCCTC
GACGAAATCTGCGAAATGGATTTAGAACTGCAGAGCAAATTACTGCGGTTTATCCAAACAGGGACCTTTCAACGGGTGGG
CGGCTCTAAAGAAGAGCATGTGGATATTCGTTTTATCAGTGCCACCAATCGCGAGCCCTGGGAAGAAGTTAAACTTGGGC
ATTTCCGTGAGGATTTGTTTTATCGCCTGCATGTTATTCCTATCGAACTGCCACCCCTGCGCGCACGGGGGAATGATGTG
CTCTTGCTGGCCAAACAATTATTAAAAACCTACAGCAAAGAAGAAGGTAAAAAGTTTATCGACTTTAATCCTCAGGCTGC
AGCCATGCTACAAGCCTATGATTGGCCTGGCAATGTAAGGCAACTACAGAACGTGATCCGCCAGATTGTGGTACTCAATG
ACGCAAGCCATGTTGAGCCAAGTATGTTCCCCACACCGCTAAAGCCGCTAGCACAGCCTCAAACAAAAGCTCAGCTGCAG
ACTAAGATGCAAGTCGAAGCGACAAAAGTGGACATTGATACACTCGTTCAAGTGGCGAGTCGCGAATTATTGTCAGAGTC
CACGCAAGAGGCGCATACACATACAGCTGATCAACAGCGGATCCAACCGCTTTGGTTAACCGAGAAGCAAACGATAGAAG
GGGCGATAGCCCTGTGTGATGGTAATGTCCCTAAAGCGGCCGCACTGCTGGACATTAGCCCATCGACCATTTATCGCAAA
CGCATGACATGGGAAGAACAAGCGGAACGTTCAAGCTCATAA

Upstream 100 bases:

>100_bases
AACAGCTCGGTGCCATTCCCGAGCTGATGGCACAGATTAATGTCCTCGGAAAACAGACTCACAGCCTATTAACGGAACGA
TTTATTCAATAGGGATAGCT

Downstream 100 bases:

>100_bases
TTGTTCCGTCTTGAGCCGCTGACACTTGCGTTAACAAGAGCTTCAACAGATAGCTAAACAATGTGCTTTCACATTGAACG
TCAACAGTGTCTGCGGTTAG

Product: two component, sigma54 specific, Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MNYSALLVEDSMSLGALYTEYLRAEDINVTHVHYGADALKELSNWQPDLLILDIKLPDMSGLDILKQVQQSHPHISTIMI
TAHGSIDIAIDAMRSGAFDFLVKPFDAKRLSITVRNALKQKQLLELVTQYENSLPKGHYQGFIGDSLAMQSVYKTIDCVA
NSKASVFIMGESGTGKEVCAQAIHQVGNRADKPFIALNCASIPKELIESEIFGHCKGAFTGAHNNRDGAATRADGGTLFL
DEICEMDLELQSKLLRFIQTGTFQRVGGSKEEHVDIRFISATNREPWEEVKLGHFREDLFYRLHVIPIELPPLRARGNDV
LLLAKQLLKTYSKEEGKKFIDFNPQAAAMLQAYDWPGNVRQLQNVIRQIVVLNDASHVEPSMFPTPLKPLAQPQTKAQLQ
TKMQVEATKVDIDTLVQVASRELLSESTQEAHTHTADQQRIQPLWLTEKQTIEGAIALCDGNVPKAAALLDISPSTIYRK
RMTWEEQAERSSS

Sequences:

>Translated_493_residues
MNYSALLVEDSMSLGALYTEYLRAEDINVTHVHYGADALKELSNWQPDLLILDIKLPDMSGLDILKQVQQSHPHISTIMI
TAHGSIDIAIDAMRSGAFDFLVKPFDAKRLSITVRNALKQKQLLELVTQYENSLPKGHYQGFIGDSLAMQSVYKTIDCVA
NSKASVFIMGESGTGKEVCAQAIHQVGNRADKPFIALNCASIPKELIESEIFGHCKGAFTGAHNNRDGAATRADGGTLFL
DEICEMDLELQSKLLRFIQTGTFQRVGGSKEEHVDIRFISATNREPWEEVKLGHFREDLFYRLHVIPIELPPLRARGNDV
LLLAKQLLKTYSKEEGKKFIDFNPQAAAMLQAYDWPGNVRQLQNVIRQIVVLNDASHVEPSMFPTPLKPLAQPQTKAQLQ
TKMQVEATKVDIDTLVQVASRELLSESTQEAHTHTADQQRIQPLWLTEKQTIEGAIALCDGNVPKAAALLDISPSTIYRK
RMTWEEQAERSSS
>Mature_493_residues
MNYSALLVEDSMSLGALYTEYLRAEDINVTHVHYGADALKELSNWQPDLLILDIKLPDMSGLDILKQVQQSHPHISTIMI
TAHGSIDIAIDAMRSGAFDFLVKPFDAKRLSITVRNALKQKQLLELVTQYENSLPKGHYQGFIGDSLAMQSVYKTIDCVA
NSKASVFIMGESGTGKEVCAQAIHQVGNRADKPFIALNCASIPKELIESEIFGHCKGAFTGAHNNRDGAATRADGGTLFL
DEICEMDLELQSKLLRFIQTGTFQRVGGSKEEHVDIRFISATNREPWEEVKLGHFREDLFYRLHVIPIELPPLRARGNDV
LLLAKQLLKTYSKEEGKKFIDFNPQAAAMLQAYDWPGNVRQLQNVIRQIVVLNDASHVEPSMFPTPLKPLAQPQTKAQLQ
TKMQVEATKVDIDTLVQVASRELLSESTQEAHTHTADQQRIQPLWLTEKQTIEGAIALCDGNVPKAAALLDISPSTIYRK
RMTWEEQAERSSS

Specific function: Involved in the regulation of different processes depending on the cell density. Acts together with sigma-54 to repress, perhaps indirectly, some genes [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=394, Percent_Identity=42.3857868020305, Blast_Score=318, Evalue=6e-88,
Organism=Escherichia coli, GI1790299, Length=474, Percent_Identity=39.0295358649789, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1790437, Length=484, Percent_Identity=36.3636363636364, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1788905, Length=371, Percent_Identity=40.4312668463612, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI87082117, Length=274, Percent_Identity=47.0802919708029, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI87082152, Length=306, Percent_Identity=42.483660130719, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789233, Length=258, Percent_Identity=44.5736434108527, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789087, Length=300, Percent_Identity=41, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1786524, Length=351, Percent_Identity=35.8974358974359, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787583, Length=242, Percent_Identity=40.9090909090909, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87081872, Length=236, Percent_Identity=40.6779661016949, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1789828, Length=269, Percent_Identity=28.996282527881, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI87081858, Length=321, Percent_Identity=29.2834890965732, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1786838, Length=122, Percent_Identity=31.1475409836066, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=33.0578512396694, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1786784, Length=126, Percent_Identity=30.1587301587302, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 55034; Mature: 55034

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSALLVEDSMSLGALYTEYLRAEDINVTHVHYGADALKELSNWQPDLLILDIKLPDMS
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCEEEEEEECCCCC
GLDILKQVQQSHPHISTIMITAHGSIDIAIDAMRSGAFDFLVKPFDAKRLSITVRNALKQ
CHHHHHHHHHCCCCEEEEEEEECCCEEEEEEHHHCCCHHEEECCCCCCEEEEHHHHHHHH
KQLLELVTQYENSLPKGHYQGFIGDSLAMQSVYKTIDCVANSKASVFIMGESGTGKEVCA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
QAIHQVGNRADKPFIALNCASIPKELIESEIFGHCKGAFTGAHNNRDGAATRADGGTLFL
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCEEEH
DEICEMDLELQSKLLRFIQTGTFQRVGGSKEEHVDIRFISATNREPWEEVKLGHFREDLF
HHHHCCCHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHE
YRLHVIPIELPPLRARGNDVLLLAKQLLKTYSKEEGKKFIDFNPQAAAMLQAYDWPGNVR
EEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHCCCCCCCHH
QLQNVIRQIVVLNDASHVEPSMFPTPLKPLAQPQTKAQLQTKMQVEATKVDIDTLVQVAS
HHHHHHHHHHEECCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEEECHHHHHHHHH
RELLSESTQEAHTHTADQQRIQPLWLTEKQTIEGAIALCDGNVPKAAALLDISPSTIYRK
HHHHHHHHHHHHHCCCHHHHCCCEECCCHHHHCCEEEEECCCCCCCEEEEECCCHHHHHH
RMTWEEQAERSSS
HCCHHHHHHCCCC
>Mature Secondary Structure
MNYSALLVEDSMSLGALYTEYLRAEDINVTHVHYGADALKELSNWQPDLLILDIKLPDMS
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCEEEEEEECCCCC
GLDILKQVQQSHPHISTIMITAHGSIDIAIDAMRSGAFDFLVKPFDAKRLSITVRNALKQ
CHHHHHHHHHCCCCEEEEEEEECCCEEEEEEHHHCCCHHEEECCCCCCEEEEHHHHHHHH
KQLLELVTQYENSLPKGHYQGFIGDSLAMQSVYKTIDCVANSKASVFIMGESGTGKEVCA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
QAIHQVGNRADKPFIALNCASIPKELIESEIFGHCKGAFTGAHNNRDGAATRADGGTLFL
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCEEEH
DEICEMDLELQSKLLRFIQTGTFQRVGGSKEEHVDIRFISATNREPWEEVKLGHFREDLF
HHHHCCCHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHE
YRLHVIPIELPPLRARGNDVLLLAKQLLKTYSKEEGKKFIDFNPQAAAMLQAYDWPGNVR
EEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHCCCCCCCHH
QLQNVIRQIVVLNDASHVEPSMFPTPLKPLAQPQTKAQLQTKMQVEATKVDIDTLVQVAS
HHHHHHHHHHEECCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEEECHHHHHHHHH
RELLSESTQEAHTHTADQQRIQPLWLTEKQTIEGAIALCDGNVPKAAALLDISPSTIYRK
HHHHHHHHHHHHHCCCHHHHCCCEECCCHHHHCCEEEEECCCCCCCEEEEECCCHHHHHH
RMTWEEQAERSSS
HCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301; 9748465 [H]