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The map label for this gene is fadH [H]

Identifier: 117920410

GI number: 117920410

Start: 2338884

End: 2340902

Strand: Direct

Name: fadH [H]

Synonym: Shewana3_1965

Alternate gene names: 117920410

Gene position: 2338884-2340902 (Clockwise)

Preceding gene: 117920407

Following gene: 117920417

Centisome position: 47.04

GC content: 50.22

Gene sequence:

>2019_bases
ATGTCGTTTCCCCATTTATTAGAACCCTTAGATCTGGGATTCACCCAGCTCAAAAATCGTGTGTTAATGGGCTCCATGCA
CACGGGTTTAGAAGAAGAAAAGGGCGGATTTGAGAAACTGGCAGCGTTTTATAAAGAGCGCGCGTTAGGCGGCGTCGGTT
TAATTGTCACCGGCGGTATCTCACCCAACCTACGTGGTCGTTTGACTCCCCATGCGTGTCAGCTGAGTTTCCCATGGCAA
GTGGGTAAACACCGCATCGTGACTCAAGCGGTGCACGAGGCTGGCGGTAAAATCTGTATGCAAATTCTGCATGCGGGGCG
TTATGGTTACCATCCTTTTTCACAGGCACCGAGTAGAATCAAGTCGCCTATCACTCCCTTTACGCCTTCGGCCATGTCGA
GCCGTCAAGTACGCGCCACCATTAAGGATTACGCCAGTTCTGCCGCCTTAGCGAAAAGAGCGGGATACGATGGCGTAGAA
GTGATGGGCTCTGAAGGCTATTTGATCAACCAATTTATCAGTTCGCGCACCAATACCCGCACCGATGAATGGGGCGGCAG
TTTTGAAAAACGTGCGCAATTTCCGATAGAGATTGTGAATGCCATTCGCGCCAAAGTAGGCAAAGATTTTATTATTATCT
TCCGCTTATCCATGCTCGACTTAGTCGACAACGGCTCCACCTGGGACGAAGTAGTGCAATTGGCCAAGTGGCTCGAGCAT
GTGGGGGTGTCGATTATCAATACAGGGATCGGCTGGCATGAGGCCCGTGTGCCAACCATTGCGACCAGTGTGCCGCGCGG
TGCCTTTGCTTGGGTGACTGAAAAACTTAAAAAGTCGGTTTCAGTCCCCTTGATTGCCACAAACCGTATCAATACGCCTG
AGATTGGCGAGCAAATCATCGCCTCTGGTCAAGCGGATATGGTGTCTATGGCACGGCCGTTTTTGGCCGATCCTGAATTT
GTTAATAAAGCGGCGGCCAACACGCCAGAGCTTATCAATACCTGTATTGGCTGTAATCAGGCCTGTTTGGATCATACATT
CTCACTCAAACGTGCCACTTGCTTGGTCAACCCTCGCGCCTGTTATGAGACCGAAATTAACTTTTTACCCACCAATAACA
AGAAGCGTATCGCAGTGATGGGCGCGGGCCCTGCGGGGATGGCATTTTCGGTGTATGCGGCCATGCGTGGCCATGAGGTC
GTGCTTTTTGAAGCAAAATCCGAGGTGGGTGGGCAGTTTAATCTGGCACGTAAAATCCCAGGAAAAGAAGAGTTTAACGA
GACGATTCGTTATTTCCTTAATCAAATCAAGCTCCATAAAATCGATTTGCGCTTAAATACCCGTTTGGATGCTAAGGTGC
TTGAAACCGAAACCTTTGATGAAATCGTTATCGCCTCGGGCGTGGTCCCGCGCGAGTTAAGTTTGCCAGGTTTTGATAGC
CCCAAAGTGGTGGATTATCAACAGGTGCTGACGGGCCAAGCCACTATTGGCAACAAAGTGGCCCTGATTGGTGCCGGCGG
CATTGGATTTGATATGGCGCATTACCTCTGCGAATCAGAGTCGAGCACCCTCAATCCTGAAAAATGGTTAAAGCAGTGGG
GCATAGACAAACAATATCAGCATGCGGGTGGTTTAGCCGAGCCTGAAGTCGATAATAGCGACCATAGACAAGTCTACTTG
CTGCAACGCAAGACTTCTAAGATGGGCCAAGGCTTAGGTAAAACCACCGGCTGGATCCACCGTTTAGTGTTAAAACAGCA
CGATGTGAAGATGAAAACCGGCGTTAACTATGACAAGTTTGACAATGCGGGTCTGCATATCCGTGTTGGCGAGCAAACCG
AAGTGTTGGCCGTGGATAATGTGATCCTCTGTGCCGGACAAGAATCTAACCGCACCTTAGTCGATGAGATGAAAGCAACG
GGGATTCCTGTGCATTTGATTGGCGGTGTCGATGTGGCCGCCGAGCTCGATGCAAAACGCGCCATTCGTCAAGGCGCAGA
GCTTGCGATGCGACTGTAG

Upstream 100 bases:

>100_bases
ATTGTAAAGGATTTTAACTTTTAACCCCCTAGCAACAGTTGAGCTTACATTTGACTCAAGGTATGCTCATTTAAATCACT
TGTTTAAAAAGGATGTTTGA

Downstream 100 bases:

>100_bases
TTGTTAAGCTATTTCACCAATAAAAAGCCTGAGTTTAACTCAGGCTTTTTTGTTGATTTTGACTCAGGCTTTTTTGTTGA
TTGATATGAAGATAAGAGCC

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLTPHACQLSFPWQ
VGKHRIVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSRIKSPITPFTPSAMSSRQVRATIKDYASSAALAKRAGYDGVE
VMGSEGYLINQFISSRTNTRTDEWGGSFEKRAQFPIEIVNAIRAKVGKDFIIIFRLSMLDLVDNGSTWDEVVQLAKWLEH
VGVSIINTGIGWHEARVPTIATSVPRGAFAWVTEKLKKSVSVPLIATNRINTPEIGEQIIASGQADMVSMARPFLADPEF
VNKAAANTPELINTCIGCNQACLDHTFSLKRATCLVNPRACYETEINFLPTNNKKRIAVMGAGPAGMAFSVYAAMRGHEV
VLFEAKSEVGGQFNLARKIPGKEEFNETIRYFLNQIKLHKIDLRLNTRLDAKVLETETFDEIVIASGVVPRELSLPGFDS
PKVVDYQQVLTGQATIGNKVALIGAGGIGFDMAHYLCESESSTLNPEKWLKQWGIDKQYQHAGGLAEPEVDNSDHRQVYL
LQRKTSKMGQGLGKTTGWIHRLVLKQHDVKMKTGVNYDKFDNAGLHIRVGEQTEVLAVDNVILCAGQESNRTLVDEMKAT
GIPVHLIGGVDVAAELDAKRAIRQGAELAMRL

Sequences:

>Translated_672_residues
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLTPHACQLSFPWQ
VGKHRIVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSRIKSPITPFTPSAMSSRQVRATIKDYASSAALAKRAGYDGVE
VMGSEGYLINQFISSRTNTRTDEWGGSFEKRAQFPIEIVNAIRAKVGKDFIIIFRLSMLDLVDNGSTWDEVVQLAKWLEH
VGVSIINTGIGWHEARVPTIATSVPRGAFAWVTEKLKKSVSVPLIATNRINTPEIGEQIIASGQADMVSMARPFLADPEF
VNKAAANTPELINTCIGCNQACLDHTFSLKRATCLVNPRACYETEINFLPTNNKKRIAVMGAGPAGMAFSVYAAMRGHEV
VLFEAKSEVGGQFNLARKIPGKEEFNETIRYFLNQIKLHKIDLRLNTRLDAKVLETETFDEIVIASGVVPRELSLPGFDS
PKVVDYQQVLTGQATIGNKVALIGAGGIGFDMAHYLCESESSTLNPEKWLKQWGIDKQYQHAGGLAEPEVDNSDHRQVYL
LQRKTSKMGQGLGKTTGWIHRLVLKQHDVKMKTGVNYDKFDNAGLHIRVGEQTEVLAVDNVILCAGQESNRTLVDEMKAT
GIPVHLIGGVDVAAELDAKRAIRQGAELAMRL
>Mature_671_residues
SFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLTPHACQLSFPWQV
GKHRIVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSRIKSPITPFTPSAMSSRQVRATIKDYASSAALAKRAGYDGVEV
MGSEGYLINQFISSRTNTRTDEWGGSFEKRAQFPIEIVNAIRAKVGKDFIIIFRLSMLDLVDNGSTWDEVVQLAKWLEHV
GVSIINTGIGWHEARVPTIATSVPRGAFAWVTEKLKKSVSVPLIATNRINTPEIGEQIIASGQADMVSMARPFLADPEFV
NKAAANTPELINTCIGCNQACLDHTFSLKRATCLVNPRACYETEINFLPTNNKKRIAVMGAGPAGMAFSVYAAMRGHEVV
LFEAKSEVGGQFNLARKIPGKEEFNETIRYFLNQIKLHKIDLRLNTRLDAKVLETETFDEIVIASGVVPRELSLPGFDSP
KVVDYQQVLTGQATIGNKVALIGAGGIGFDMAHYLCESESSTLNPEKWLKQWGIDKQYQHAGGLAEPEVDNSDHRQVYLL
QRKTSKMGQGLGKTTGWIHRLVLKQHDVKMKTGVNYDKFDNAGLHIRVGEQTEVLAVDNVILCAGQESNRTLVDEMKATG
IPVHLIGGVDVAAELDAKRAIRQGAELAMRL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=674, Percent_Identity=56.8249258160237, Blast_Score=790, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=353, Percent_Identity=27.4787535410765, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=250, Percent_Identity=26.8, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17565138, Length=250, Percent_Identity=25.6, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17540738, Length=307, Percent_Identity=24.7557003257329, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559804, Length=250, Percent_Identity=26.4, Blast_Score=83, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=248, Percent_Identity=26.2096774193548, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI72001454, Length=250, Percent_Identity=26.8, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17566914, Length=345, Percent_Identity=24.3478260869565, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=28.6324786324786, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6321973, Length=353, Percent_Identity=22.9461756373938, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73815; Mature: 73684

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGI
CCCCCCCCHHHCCHHHHHCHHEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLTPHACQLSFPWQVGKHRIVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSRI
CCCCCCCCCCCEEEEECCHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHCCHHH
KSPITPFTPSAMSSRQVRATIKDYASSAALAKRAGYDGVEVMGSEGYLINQFISSRTNTR
HCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHCCCCCC
TDEWGGSFEKRAQFPIEIVNAIRAKVGKDFIIIFRLSMLDLVDNGSTWDEVVQLAKWLEH
CHHCCCCHHHHCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHH
VGVSIINTGIGWHEARVPTIATSVPRGAFAWVTEKLKKSVSVPLIATNRINTPEIGEQII
CCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
ASGQADMVSMARPFLADPEFVNKAAANTPELINTCIGCNQACLDHTFSLKRATCLVNPRA
HCCCHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHEEEEECCCH
CYETEINFLPTNNKKRIAVMGAGPAGMAFSVYAAMRGHEVVLFEAKSEVGGQFNLARKIP
HHCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHCCC
GKEEFNETIRYFLNQIKLHKIDLRLNTRLDAKVLETETFDEIVIASGVVPRELSLPGFDS
CHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCC
PKVVDYQQVLTGQATIGNKVALIGAGGIGFDMAHYLCESESSTLNPEKWLKQWGIDKQYQ
CCEECHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHH
HAGGLAEPEVDNSDHRQVYLLQRKTSKMGQGLGKTTGWIHRLVLKQHDVKMKTGVNYDKF
HCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCC
DNAGLHIRVGEQTEVLAVDNVILCAGQESNRTLVDEMKATGIPVHLIGGVDVAAELDAKR
CCCCEEEEECCCCEEEEECCEEEEECCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHH
AIRQGAELAMRL
HHHHHHHHHHCC
>Mature Secondary Structure 
SFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGI
CCCCCCCHHHCCHHHHHCHHEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLTPHACQLSFPWQVGKHRIVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSRI
CCCCCCCCCCCEEEEECCHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHCCHHH
KSPITPFTPSAMSSRQVRATIKDYASSAALAKRAGYDGVEVMGSEGYLINQFISSRTNTR
HCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHCCCCCC
TDEWGGSFEKRAQFPIEIVNAIRAKVGKDFIIIFRLSMLDLVDNGSTWDEVVQLAKWLEH
CHHCCCCHHHHCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHH
VGVSIINTGIGWHEARVPTIATSVPRGAFAWVTEKLKKSVSVPLIATNRINTPEIGEQII
CCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
ASGQADMVSMARPFLADPEFVNKAAANTPELINTCIGCNQACLDHTFSLKRATCLVNPRA
HCCCHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHEEEEECCCH
CYETEINFLPTNNKKRIAVMGAGPAGMAFSVYAAMRGHEVVLFEAKSEVGGQFNLARKIP
HHCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHCCC
GKEEFNETIRYFLNQIKLHKIDLRLNTRLDAKVLETETFDEIVIASGVVPRELSLPGFDS
CHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCC
PKVVDYQQVLTGQATIGNKVALIGAGGIGFDMAHYLCESESSTLNPEKWLKQWGIDKQYQ
CCEECHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHH
HAGGLAEPEVDNSDHRQVYLLQRKTSKMGQGLGKTTGWIHRLVLKQHDVKMKTGVNYDKF
HCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCC
DNAGLHIRVGEQTEVLAVDNVILCAGQESNRTLVDEMKATGIPVHLIGGVDVAAELDAKR
CCCCEEEEECCCCEEEEECCEEEEECCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHH
AIRQGAELAMRL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]