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The map label for this gene is kdsB [H]

Identifier: 117920351

GI number: 117920351

Start: 2262727

End: 2263464

Strand: Reverse

Name: kdsB [H]

Synonym: Shewana3_1906

Alternate gene names: 117920351

Gene position: 2263464-2262727 (Counterclockwise)

Preceding gene: 117920352

Following gene: 117920350

Centisome position: 45.52

GC content: 51.76

Gene sequence:

>738_bases
ATGAATGTGACTCTGTTAATCCCGGCGCGTTACGGTTCAAGCCGCTTCCCGGGCAAGCCCTTAGCCCCGATTAACGGCAA
GCCGATGATCCAACACGTGTACGAACGCGCGTCGTTAGCCAAAGGCCTCACCAATATTTATGTTGCAACCGATGATGAGC
GTATCAAAAGCGCCGTAGAAGGCTTCGGTGGCAAAGTGGTCATGACCAGCCCTGATGCGGCATCGGGCACAGACCGTATC
AATGATGCGATTAACCAATTAGGTTTGAAGGATGACGATCTGGTTATCAACCTTCAAGGCGACCAACCCCTAATCGACCC
GACTTCTATCGAGCAGGTGATCAGCCTCTTCGAACGTCATCCAGGCGAGTTCGAAATGGCGACCCTCGGCTATGAAATTG
TCAACAAAGCCGAGCTCGACGATCCTATGCATGTGAAGATGGTGTTCGATAACGACTACTACGCGCTATATTTCTCCCGC
GCGCGTATTCCCTTCGGCCGCGATACCAAAGATTATCCAGTTTACAAGCACTTAGGCGTGTATGCTTACACCCGCAGATT
CGTGCAAGCCTTCGCCGCCCTCCCCTTAGGTCGTCTCGAAGATCTGGAAAAGTTAGAGCAGCTACGCGCCCTAGAACATG
GCCATAAGATCAAAGTCGCCATCAGCGCCTTCGACTCAATCGAAGTTGACACGCCGGAAGATATTCGTAAGTGTGAGCAG
CGTTTAGCCGTTGATTAA

Upstream 100 bases:

>100_bases
CTGTTCCGTCGCATTTAAGCTCTCAAGCAGATGACAAGGGCTCGTTGTGAGCCCTTTTGTCTATCTACACTGCATATCTT
TGATAAATTAGGATAATTTA

Downstream 100 bases:

>100_bases
TCAGGGCGTTGCTCAATAAGGAGTTGTCATGTCGAGCTTAGAAGTGTGGATCATTATTATTTTGGTGGTGGGTGTGATTG
CCAGCAATCTTGCCGCACTA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDERIKSAVEGFGGKVVMTSPDAASGTDRI
NDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGYEIVNKAELDDPMHVKMVFDNDYYALYFSR
ARIPFGRDTKDYPVYKHLGVYAYTRRFVQAFAALPLGRLEDLEKLEQLRALEHGHKIKVAISAFDSIEVDTPEDIRKCEQ
RLAVD

Sequences:

>Translated_245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDERIKSAVEGFGGKVVMTSPDAASGTDRI
NDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGYEIVNKAELDDPMHVKMVFDNDYYALYFSR
ARIPFGRDTKDYPVYKHLGVYAYTRRFVQAFAALPLGRLEDLEKLEQLRALEHGHKIKVAISAFDSIEVDTPEDIRKCEQ
RLAVD
>Mature_245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDERIKSAVEGFGGKVVMTSPDAASGTDRI
NDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGYEIVNKAELDDPMHVKMVFDNDYYALYFSR
ARIPFGRDTKDYPVYKHLGVYAYTRRFVQAFAALPLGRLEDLEKLEQLRALEHGHKIKVAISAFDSIEVDTPEDIRKCEQ
RLAVD

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=251, Percent_Identity=44.2231075697211, Blast_Score=192, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27502; Mature: 27502

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDERIKSAVE
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
GFGGKVVMTSPDAASGTDRINDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERH
CCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
PGEFEMATLGYEIVNKAELDDPMHVKMVFDNDYYALYFSRARIPFGRDTKDYPVYKHLGV
CCCEEHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEEEEECCCCCCCCCCCCHHHHHHH
YAYTRRFVQAFAALPLGRLEDLEKLEQLRALEHGHKIKVAISAFDSIEVDTPEDIRKCEQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHH
RLAVD
HHCCC
>Mature Secondary Structure
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDERIKSAVE
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
GFGGKVVMTSPDAASGTDRINDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERH
CCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
PGEFEMATLGYEIVNKAELDDPMHVKMVFDNDYYALYFSRARIPFGRDTKDYPVYKHLGV
CCCEEHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEEEEECCCCCCCCCCCCHHHHHHH
YAYTRRFVQAFAALPLGRLEDLEKLEQLRALEHGHKIKVAISAFDSIEVDTPEDIRKCEQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHH
RLAVD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA