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The map label for this gene is yafC [C]

Identifier: 117920283

GI number: 117920283

Start: 2177603

End: 2178484

Strand: Reverse

Name: yafC [C]

Synonym: Shewana3_1836

Alternate gene names: 117920283

Gene position: 2178484-2177603 (Counterclockwise)

Preceding gene: 117920288

Following gene: 117920281

Centisome position: 43.81

GC content: 49.32

Gene sequence:

>882_bases
ATGTACCTTTGGGATGGCATATCAGAATTTGTAGCAGTAGCCGAAGTCGAGAACTTTACCTTGGCCGCACTGCGCCTCAA
TGTGTCCACCGCCCACGTGAGTCGGCAAATCGGTGCACTGGAAAATCGACTCGGTACTAAGCTGTTTTATCGTACAACAC
GCAAGGTATCGCTCACCGAAGAAGGCACGATTTATTATCGTCATTGCCGCCAATTGCAAACAGGCCTCGAGGAGGCCGAG
CGGGCGATTACCGATCTAAAAGGTTCGCCCCAAGGATTGGTAAAACTCACCGCACCCGTGGCCTACGGCGAAAAATTTAT
CATGCCATTACTCAATGATTTTATGGTGCAATATCCCAGCGTGGAATTTAATGTCGACTTGACCAACAGAACCTTAGATT
TGATTGAAGGCGGCTACGATTTGGCCATTCGCCTTGGTAAACTCGCCGACTCCAGCCTGATGGCTAAACCCTTGAGTAGC
CGCACCCATTATGTGGCCGCCTCGCCCAGTTACGTTGAAAAATACGGTGAGCCCCATACGCTTTCGGAGTTAAATCAACA
TAATTGCCTGATCGGGAATCACAATTACTGGCGCTTTATTGAAAATGGCCGCGAGCGCAATATTAAGGTACGTGGCAACC
TTATCTGCAACAGCGGTTACGCCCTGCGAGATGCAGCATTAAAGGGTATAGGAATAGTGCAACTCCCTGATTATTATATT
GAAGAAGATATACATGCAGGCCGACTCATCTCATTCCTCGACGCGCACCGCGAAGCTAAAGAAGGCATTTGGGCGCTCTA
TCCGCAGAATCGTCACCTGAGCGCAAAAGTGCGGGTATTAGTGGATTATCTCGCGGAAAAACTGGCGATGGAGGATGCGT
AG

Upstream 100 bases:

>100_bases
CTTAAAAATAGTGTGCGGTAATGCAGTCACTAGATTGTATTTATTTCCTGATGATTGATAATCTAGCATTTTGGCAATTC
ATTTTTACCGAGAAGCAACA

Downstream 100 bases:

>100_bases
TAACGAGTCCATTGCAGCGAACCAAAGTAACAAATCACCCAATCTTGCGACCAATAACGCGCTTGAGCTTGACGGATTAC
TGGCTATTTAGCGCCAGTTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MYLWDGISEFVAVAEVENFTLAALRLNVSTAHVSRQIGALENRLGTKLFYRTTRKVSLTEEGTIYYRHCRQLQTGLEEAE
RAITDLKGSPQGLVKLTAPVAYGEKFIMPLLNDFMVQYPSVEFNVDLTNRTLDLIEGGYDLAIRLGKLADSSLMAKPLSS
RTHYVAASPSYVEKYGEPHTLSELNQHNCLIGNHNYWRFIENGRERNIKVRGNLICNSGYALRDAALKGIGIVQLPDYYI
EEDIHAGRLISFLDAHREAKEGIWALYPQNRHLSAKVRVLVDYLAEKLAMEDA

Sequences:

>Translated_293_residues
MYLWDGISEFVAVAEVENFTLAALRLNVSTAHVSRQIGALENRLGTKLFYRTTRKVSLTEEGTIYYRHCRQLQTGLEEAE
RAITDLKGSPQGLVKLTAPVAYGEKFIMPLLNDFMVQYPSVEFNVDLTNRTLDLIEGGYDLAIRLGKLADSSLMAKPLSS
RTHYVAASPSYVEKYGEPHTLSELNQHNCLIGNHNYWRFIENGRERNIKVRGNLICNSGYALRDAALKGIGIVQLPDYYI
EEDIHAGRLISFLDAHREAKEGIWALYPQNRHLSAKVRVLVDYLAEKLAMEDA
>Mature_293_residues
MYLWDGISEFVAVAEVENFTLAALRLNVSTAHVSRQIGALENRLGTKLFYRTTRKVSLTEEGTIYYRHCRQLQTGLEEAE
RAITDLKGSPQGLVKLTAPVAYGEKFIMPLLNDFMVQYPSVEFNVDLTNRTLDLIEGGYDLAIRLGKLADSSLMAKPLSS
RTHYVAASPSYVEKYGEPHTLSELNQHNCLIGNHNYWRFIENGRERNIKVRGNLICNSGYALRDAALKGIGIVQLPDYYI
EEDIHAGRLISFLDAHREAKEGIWALYPQNRHLSAKVRVLVDYLAEKLAMEDA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=282, Percent_Identity=35.4609929078014, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI145693193, Length=283, Percent_Identity=33.2155477031802, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789440, Length=281, Percent_Identity=29.8932384341637, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI87081978, Length=285, Percent_Identity=30.5263157894737, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=30.5555555555556, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787589, Length=288, Percent_Identity=28.125, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789639, Length=284, Percent_Identity=28.169014084507, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1790011, Length=294, Percent_Identity=25.8503401360544, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786448, Length=283, Percent_Identity=24.0282685512367, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788706, Length=252, Percent_Identity=27.3809523809524, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789173, Length=248, Percent_Identity=26.6129032258064, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI157672245, Length=155, Percent_Identity=31.6129032258064, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790783, Length=259, Percent_Identity=26.6409266409266, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33124; Mature: 33124

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLWDGISEFVAVAEVENFTLAALRLNVSTAHVSRQIGALENRLGTKLFYRTTRKVSLTE
CCCCCCHHHHHHHHHHCCEEEEEEEEECHHHHHHHHHHHHHHHHCCHHEEEECCEEEECC
EGTIYYRHCRQLQTGLEEAERAITDLKGSPQGLVKLTAPVAYGEKFIMPLLNDFMVQYPS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHCCHHHHHHHHHHHHHHCCC
VEFNVDLTNRTLDLIEGGYDLAIRLGKLADSSLMAKPLSSRTHYVAASPSYVEKYGEPHT
EEEEEEECCCCHHHHCCCCEEEEEECCCCCCHHHHCCCCCCCEEEEECCHHHHHCCCCCC
LSELNQHNCLIGNHNYWRFIENGRERNIKVRGNLICNSGYALRDAALKGIGIVQLPDYYI
HHHHCCCCCEECCCCEEEEECCCCCCEEEEEEEEEECCCCEEHHHHHCCCEEEECCCHHH
EEDIHAGRLISFLDAHREAKEGIWALYPQNRHLSAKVRVLVDYLAEKLAMEDA
HCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYLWDGISEFVAVAEVENFTLAALRLNVSTAHVSRQIGALENRLGTKLFYRTTRKVSLTE
CCCCCCHHHHHHHHHHCCEEEEEEEEECHHHHHHHHHHHHHHHHCCHHEEEECCEEEECC
EGTIYYRHCRQLQTGLEEAERAITDLKGSPQGLVKLTAPVAYGEKFIMPLLNDFMVQYPS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHCCHHHHHHHHHHHHHHCCC
VEFNVDLTNRTLDLIEGGYDLAIRLGKLADSSLMAKPLSSRTHYVAASPSYVEKYGEPHT
EEEEEEECCCCHHHHCCCCEEEEEECCCCCCHHHHCCCCCCCEEEEECCHHHHHCCCCCC
LSELNQHNCLIGNHNYWRFIENGRERNIKVRGNLICNSGYALRDAALKGIGIVQLPDYYI
HHHHCCCCCEECCCCEEEEECCCCCCEEEEEEEEEECCCCEEHHHHHCCCEEEECCCHHH
EEDIHAGRLISFLDAHREAKEGIWALYPQNRHLSAKVRVLVDYLAEKLAMEDA
HCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]