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The map label for this gene is apr [H]

Identifier: 117919891

GI number: 117919891

Start: 1671430

End: 1673859

Strand: Reverse

Name: apr [H]

Synonym: Shewana3_1443

Alternate gene names: 117919891

Gene position: 1673859-1671430 (Counterclockwise)

Preceding gene: 117919892

Following gene: 117919880

Centisome position: 33.66

GC content: 50.99

Gene sequence:

>2430_bases
ATGACAATCAATCGAACCACTAAGATAGCCCTGAGTTTATCTAGCTTAGCTATTGCGATCTCGGCAGGTGTTAATGCTGC
CCCAGACGCACCAGGTTTTGCCGCAGCCAAACAAGCACAGACCTCTCCACTGCCAAAGCGCTATATCGTTAAATTTAAAA
ATGCCGATGCGCCAGCCTTGATGTCTGAAAGCAGCCTGCAGAGCAGCGATCAGCTTGCCACCACAATGAATTATCAGCCT
CAAGTAGCTGAAATTAGCGCCCAGCACAGTGTGCTAAACAAGGCGCAAGCCAAAGAAATGAAGCGTATCGGCCGCAGTAA
CAGCTACTCAGTTAAGCTGGATAACAATGGCATTAAGGCATTAAGAGCCCGCGCCGATGTGGAATATGTGGAAGAAGACA
TGCCACGCCACCTGCTAAGCGAAACAACGCCTTGGGGACAAACCTTTGTGGGTGCAACCCAATTAAGCGACAGTCAGGCC
GGCAACCGTACCATCTGTATTATCGACTCTGGTTATGACCGTGGTCATAGCGACTTAAGCGGAAACAATGTCACGGGCAC
CAACAACTCAGGTACAGGTAACTGGTACGAGCCAGGCAATAACAACGCCCATGGTACCCACGTTGCCGGTACTATCGCGG
CGATCGCCAACAACGATGGCGTGATTGGCGTAATGCCAAATCAAAATGCCAACATCCATGTGATTAAAGTCTTTAACGAG
GCTGGCTGGGGTTACTCCTCATCACTGGTGTCAGCAGTCGATACCTGTGTGGCGAATGGTGCAAACGTCGTCACCATGAG
CTTAGGCGGCGCAGGTTCAAGCACTACCGAGCGTAACGCGTTAGCGGCTCACTACAATAACGGCGTACTGTTGATTGCCG
CTGCCGGTAACGATGGTAACAATACCCACAGTTACCCTGCTTCGTACGATGCGGTGATGTCTGTGGCATCGGTCGATAAT
CATAAAGACCACTCAGCTTTCTCTCAGTACACCAACCAAGTTGAGATCTCGGGTCCTGGTGAAGCCATTCTCTCTACCGT
TACCCGCGGTGAGGGTCGCTTAGCCGATATTACTATCGGTGGTCAGTCTTACTTCAACTCAGGCGTTGTGCCGCACAATC
GCTTTACGCCATCGGGCACCAACTACGCGCCCAATCCATACAATGGCACGGCAACCGCAACCTTAGCCGAATGTACGGTT
AGCGGCTCAACCTTCAACTGCGGCAACATGGCTAACAAGGTGTGTTTAGTTGAGCGTGTGGGTAACCAAGGCACTTCATA
CCCAGAAATCAACGCAGTAAAAGCCTGTAAGAATGCAGGTGCCAGCGCCGTTATCGTGTACAGTAACAGCGCCTTACCTG
GGTTACAAAACCCCTTCTTGGTCGATGCGAACAGCGAAATCAACATGGTGTCAGTGTCTGTTGACCGTGCAACCGGTTTA
GCACTGCGTAACCAGTTAGGTGCAACAGTGACCGTAAGCAACCAAGGCAATAAGGACTACGAGTACTACAACGGTACGTC
GATGGCGACCCCGCACGTTTCTGGTGTGGCAACCTTAGTGTGGAGCTACCACCCAGAATGTAGCGCAGCTCAAGTACGTA
ACGCGCTCAAACAAACCGCTGAAGACTTAGGCACTGCAGGCCGTGATGACTACTATGGCTATGGTCTGGTCAATGCCGTT
GCAGCGAAAACCTTCTTAGATGCTTCCTGTAATGGTCCAACGGATCCGGTTGACCCTACTCCAACTGACAGCGTGTTGGT
GAACGGTGTGCCAAAAACCGGTCTAAGCGGCGCCGCCAGTGAAGAACTGCATTTCTCGTTTGAAGTGCCACAGGGTGCAA
CTAACTTAGGCTTTGTGATGAACGGTGGCACGGGTGATGCGGATCTGTACGTACAGTACGGCGCAGCGCCAACGACCTCA
AACTACGATTGCCGTCCATATAAAGGTGGTAACAGTGAATCTTGCCCAATCAGCAACGTTCAATCTGGTACTTACTACGC
GATGGTGAAAGGCTATTCAGCCTTTAGCGGTGTATCGTTAACCGCAAGCTACACAGCCCAAAGCGGTGGTGGTACTCCTA
CCACGCCAGCAAGTTACACCAATGCTGATAACTACAATATTCCTGATAACAAAACCGCAGGTATCACTAGCCCTATCACA
GTCACTCGCACGGGTAACTCAGGCACTGTGACTGCCGTGGTGAATATTGTTCACCCTTACATTGGTGATTTAAAAGTGCA
GCTCATCAGCCCTACAGGCCAAACAGCAACACTGCATAACAACACTGGCGCAGGCGCAGACAACATCAACAAGAGCTACA
CAGTTGATATGACTGGCGTGGAGTCAAGCGGTGTGTGGAAACTCAAAGCGGTTGATAGCGGCCGTGGCGACGTAGGCTAT
ATCGATAGCTGGGAACTCAAATTCCAATAA

Upstream 100 bases:

>100_bases
CAAAGATAAATTCACTAACCGAGTAGCATCTGAGTCGTAGTTATTCTTTAAAAGCACAAAATAATAATGATTAACACTAA
ATTGAACATGGAAGAAAAAC

Downstream 100 bases:

>100_bases
TCTTCGTCTAAACAAAGAGCCTGCAATTGCAGGCTCTTTTTTATTGGTCATCTTTCAGCATTTCGGGCTCGATAAGCACA
CTGTGCTCATTATCCGATAA

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 809; Mature: 808

Protein sequence:

>809_residues
MTINRTTKIALSLSSLAIAISAGVNAAPDAPGFAAAKQAQTSPLPKRYIVKFKNADAPALMSESSLQSSDQLATTMNYQP
QVAEISAQHSVLNKAQAKEMKRIGRSNSYSVKLDNNGIKALRARADVEYVEEDMPRHLLSETTPWGQTFVGATQLSDSQA
GNRTICIIDSGYDRGHSDLSGNNVTGTNNSGTGNWYEPGNNNAHGTHVAGTIAAIANNDGVIGVMPNQNANIHVIKVFNE
AGWGYSSSLVSAVDTCVANGANVVTMSLGGAGSSTTERNALAAHYNNGVLLIAAAGNDGNNTHSYPASYDAVMSVASVDN
HKDHSAFSQYTNQVEISGPGEAILSTVTRGEGRLADITIGGQSYFNSGVVPHNRFTPSGTNYAPNPYNGTATATLAECTV
SGSTFNCGNMANKVCLVERVGNQGTSYPEINAVKACKNAGASAVIVYSNSALPGLQNPFLVDANSEINMVSVSVDRATGL
ALRNQLGATVTVSNQGNKDYEYYNGTSMATPHVSGVATLVWSYHPECSAAQVRNALKQTAEDLGTAGRDDYYGYGLVNAV
AAKTFLDASCNGPTDPVDPTPTDSVLVNGVPKTGLSGAASEELHFSFEVPQGATNLGFVMNGGTGDADLYVQYGAAPTTS
NYDCRPYKGGNSESCPISNVQSGTYYAMVKGYSAFSGVSLTASYTAQSGGGTPTTPASYTNADNYNIPDNKTAGITSPIT
VTRTGNSGTVTAVVNIVHPYIGDLKVQLISPTGQTATLHNNTGAGADNINKSYTVDMTGVESSGVWKLKAVDSGRGDVGY
IDSWELKFQ

Sequences:

>Translated_809_residues
MTINRTTKIALSLSSLAIAISAGVNAAPDAPGFAAAKQAQTSPLPKRYIVKFKNADAPALMSESSLQSSDQLATTMNYQP
QVAEISAQHSVLNKAQAKEMKRIGRSNSYSVKLDNNGIKALRARADVEYVEEDMPRHLLSETTPWGQTFVGATQLSDSQA
GNRTICIIDSGYDRGHSDLSGNNVTGTNNSGTGNWYEPGNNNAHGTHVAGTIAAIANNDGVIGVMPNQNANIHVIKVFNE
AGWGYSSSLVSAVDTCVANGANVVTMSLGGAGSSTTERNALAAHYNNGVLLIAAAGNDGNNTHSYPASYDAVMSVASVDN
HKDHSAFSQYTNQVEISGPGEAILSTVTRGEGRLADITIGGQSYFNSGVVPHNRFTPSGTNYAPNPYNGTATATLAECTV
SGSTFNCGNMANKVCLVERVGNQGTSYPEINAVKACKNAGASAVIVYSNSALPGLQNPFLVDANSEINMVSVSVDRATGL
ALRNQLGATVTVSNQGNKDYEYYNGTSMATPHVSGVATLVWSYHPECSAAQVRNALKQTAEDLGTAGRDDYYGYGLVNAV
AAKTFLDASCNGPTDPVDPTPTDSVLVNGVPKTGLSGAASEELHFSFEVPQGATNLGFVMNGGTGDADLYVQYGAAPTTS
NYDCRPYKGGNSESCPISNVQSGTYYAMVKGYSAFSGVSLTASYTAQSGGGTPTTPASYTNADNYNIPDNKTAGITSPIT
VTRTGNSGTVTAVVNIVHPYIGDLKVQLISPTGQTATLHNNTGAGADNINKSYTVDMTGVESSGVWKLKAVDSGRGDVGY
IDSWELKFQ
>Mature_808_residues
TINRTTKIALSLSSLAIAISAGVNAAPDAPGFAAAKQAQTSPLPKRYIVKFKNADAPALMSESSLQSSDQLATTMNYQPQ
VAEISAQHSVLNKAQAKEMKRIGRSNSYSVKLDNNGIKALRARADVEYVEEDMPRHLLSETTPWGQTFVGATQLSDSQAG
NRTICIIDSGYDRGHSDLSGNNVTGTNNSGTGNWYEPGNNNAHGTHVAGTIAAIANNDGVIGVMPNQNANIHVIKVFNEA
GWGYSSSLVSAVDTCVANGANVVTMSLGGAGSSTTERNALAAHYNNGVLLIAAAGNDGNNTHSYPASYDAVMSVASVDNH
KDHSAFSQYTNQVEISGPGEAILSTVTRGEGRLADITIGGQSYFNSGVVPHNRFTPSGTNYAPNPYNGTATATLAECTVS
GSTFNCGNMANKVCLVERVGNQGTSYPEINAVKACKNAGASAVIVYSNSALPGLQNPFLVDANSEINMVSVSVDRATGLA
LRNQLGATVTVSNQGNKDYEYYNGTSMATPHVSGVATLVWSYHPECSAAQVRNALKQTAEDLGTAGRDDYYGYGLVNAVA
AKTFLDASCNGPTDPVDPTPTDSVLVNGVPKTGLSGAASEELHFSFEVPQGATNLGFVMNGGTGDADLYVQYGAAPTTSN
YDCRPYKGGNSESCPISNVQSGTYYAMVKGYSAFSGVSLTASYTAQSGGGTPTTPASYTNADNYNIPDNKTAGITSPITV
TRTGNSGTVTAVVNIVHPYIGDLKVQLISPTGQTATLHNNTGAGADNINKSYTVDMTGVESSGVWKLKAVDSGRGDVGYI
DSWELKFQ

Specific function: Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: =3.4.21.62 [H]

Molecular weight: Translated: 84364; Mature: 84232

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINRTTKIALSLSSLAIAISAGVNAAPDAPGFAAAKQAQTSPLPKRYIVKFKNADAPAL
CCCCCEEEEEEEEEEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCCCC
MSESSLQSSDQLATTMNYQPQVAEISAQHSVLNKAQAKEMKRIGRSNSYSVKLDNNGIKA
CCCHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEE
LRARADVEYVEEDMPRHLLSETTPWGQTFVGATQLSDSQAGNRTICIIDSGYDRGHSDLS
HHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCC
GNNVTGTNNSGTGNWYEPGNNNAHGTHVAGTIAAIANNDGVIGVMPNQNANIHVIKVFNE
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEECCCCCCEEEEEEEEC
AGWGYSSSLVSAVDTCVANGANVVTMSLGGAGSSTTERNALAAHYNNGVLLIAAAGNDGN
CCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCEEEEEECCCCCC
NTHSYPASYDAVMSVASVDNHKDHSAFSQYTNQVEISGPGEAILSTVTRGEGRLADITIG
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHCCCCEEEEEEEC
GQSYFNSGVVPHNRFTPSGTNYAPNPYNGTATATLAECTVSGSTFNCGNMANKVCLVERV
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCEEECCCCCCCEEEEEEC
GNQGTSYPEINAVKACKNAGASAVIVYSNSALPGLQNPFLVDANSEINMVSVSVDRATGL
CCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCCCEEEEEEEECCHHHH
ALRNQLGATVTVSNQGNKDYEYYNGTSMATPHVSGVATLVWSYHPECSAAQVRNALKQTA
HHHHCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
EDLGTAGRDDYYGYGLVNAVAAKTFLDASCNGPTDPVDPTPTDSVLVNGVPKTGLSGAAS
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
EELHFSFEVPQGATNLGFVMNGGTGDADLYVQYGAAPTTSNYDCRPYKGGNSESCPISNV
CCEEEEEECCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
QSGTYYAMVKGYSAFSGVSLTASYTAQSGGGTPTTPASYTNADNYNIPDNKTAGITSPIT
CCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
VTRTGNSGTVTAVVNIVHPYIGDLKVQLISPTGQTATLHNNTGAGADNINKSYTVDMTGV
EEEECCCCEEEEEEEEHHCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCEEEEEEECC
ESSGVWKLKAVDSGRGDVGYIDSWELKFQ
CCCCEEEEEEECCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
TINRTTKIALSLSSLAIAISAGVNAAPDAPGFAAAKQAQTSPLPKRYIVKFKNADAPAL
CCCCEEEEEEEEEEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCCCC
MSESSLQSSDQLATTMNYQPQVAEISAQHSVLNKAQAKEMKRIGRSNSYSVKLDNNGIKA
CCCHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEE
LRARADVEYVEEDMPRHLLSETTPWGQTFVGATQLSDSQAGNRTICIIDSGYDRGHSDLS
HHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCC
GNNVTGTNNSGTGNWYEPGNNNAHGTHVAGTIAAIANNDGVIGVMPNQNANIHVIKVFNE
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEECCCCCCEEEEEEEEC
AGWGYSSSLVSAVDTCVANGANVVTMSLGGAGSSTTERNALAAHYNNGVLLIAAAGNDGN
CCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCEEEEEECCCCCC
NTHSYPASYDAVMSVASVDNHKDHSAFSQYTNQVEISGPGEAILSTVTRGEGRLADITIG
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHCCCCEEEEEEEC
GQSYFNSGVVPHNRFTPSGTNYAPNPYNGTATATLAECTVSGSTFNCGNMANKVCLVERV
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCEEECCCCCCCEEEEEEC
GNQGTSYPEINAVKACKNAGASAVIVYSNSALPGLQNPFLVDANSEINMVSVSVDRATGL
CCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEECCCCEEEEEEEECCHHHH
ALRNQLGATVTVSNQGNKDYEYYNGTSMATPHVSGVATLVWSYHPECSAAQVRNALKQTA
HHHHCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
EDLGTAGRDDYYGYGLVNAVAAKTFLDASCNGPTDPVDPTPTDSVLVNGVPKTGLSGAAS
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
EELHFSFEVPQGATNLGFVMNGGTGDADLYVQYGAAPTTSNYDCRPYKGGNSESCPISNV
CCEEEEEECCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
QSGTYYAMVKGYSAFSGVSLTASYTAQSGGGTPTTPASYTNADNYNIPDNKTAGITSPIT
CCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
VTRTGNSGTVTAVVNIVHPYIGDLKVQLISPTGQTATLHNNTGAGADNINKSYTVDMTGV
EEEECCCCEEEEEEEEHHCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCEEEEEEECC
ESSGVWKLKAVDSGRGDVGYIDSWELKFQ
CCCCEEEEEEECCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3001653; 4967581; 8512925; 9425066 [H]