Click here to switch to the map view.

The map label for this gene is ltaE [H]

Identifier: 117919657

GI number: 117919657

Start: 1412053

End: 1413066

Strand: Direct

Name: ltaE [H]

Synonym: Shewana3_1208

Alternate gene names: 117919657

Gene position: 1412053-1413066 (Clockwise)

Preceding gene: 117919653

Following gene: 117919658

Centisome position: 28.4

GC content: 52.07

Gene sequence:

>1014_bases
ATGATAGATTTACGCAGTGATACCGTGACCCAGCCAACAGAGGCGATGCGCTTAGCCATGTCGAGGGCTGAAGTGGGTGA
TGATGTTTATGGTGATGATCCGACCGTCAACAGTTTGCAAGATATGGCCGCAGAGATGTTTGGTTTTGAGAGTGCGCTGT
TTACGGCATCGGGCACTCAGGCCAATTTACTCGCATTGATGGCACATTGTGAGCGCGGGGATGAATACCTGTGCGGCCAG
CAGGCGCATAACTATAAATTTGAGGGCGGTGGCGCTGCGGTTCTCGGCAGCATTCAGCCACAACCGCTGACCAATCAGCT
GGATGGCACTATCGCCTTGACCGATATTGAAGCGGCGATTAAACCCGATGACATTCACTTTGCGCGCACGCGCTTACTGA
GCCTAGAAAACACTATCGGCGGTAAAGTCTTGCCCCAGACTTATCTTGCCAATGCGCAGGCACTGGCATTTCAGCGTGGC
TTAAAAATTCATTTAGATGGCGCTAGGGTGGCCAATGCCGCCGTGGCGCAGGGGATAGGGATTGCCGATATTGCGGGGCA
TTTTGATTCGGTCTCCATCTGTTTATCCAAGGGATTATGCGCGCCTGTTGGCTCGCTGCTCCTAGGTGATGAGCGCCTAA
TTAAAAAGGCCACGCGCTGGCGTAAAATGCTTGGCGGCGGCATGCGCCAGGCGGGGATTTTAGCGGCGGCGGGTAAATTA
GCGCTCATAGAGCAGGTTGAGAGACTTGGGGAAGACCATGAAAATGCTGCGTATCTTGCCCAGCAATTGAGTCAGTTGAG
TGAGTTTGAAATCGATTTAGCCGCCGTTCAAACCAATATGGTGTTTGCAAACCTCGCGACCAATGTCGATGAGAAAGCGC
TGGCGAAACGTTGCCGTGAGGCGGGCATTATCATCAGCCCTGGCCGCACGCTACGCTTTGTGACCCATAAAGATGTGTCG
CGTCAGGATATTGATAAAGTGCTACAAGTGTTTAAATTACATTTGCAGGCATAA

Upstream 100 bases:

>100_bases
GACATAAAGGCAAACTATACAAATTTTTCCTTTGAGGCTAGAGTCGCACTTACGCGATGAATATCCGCGTCGGGGATAGG
CAGAAGAAGTCGAGGACAAG

Downstream 100 bases:

>100_bases
TCGGCGTTGAGCCCAAGTGAAAACTTGGGCTTTTTTATACATCTTGCTTACTATATCGCCGATTTTAAAATCAAAAGTCG
AATTGTGAGCCAGATGCTAG

Product: L-threonine aldolase

Products: NA

Alternate protein names: Low-specificity L-TA [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIDLRSDTVTQPTEAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTASGTQANLLALMAHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLTNQLDGTIALTDIEAAIKPDDIHFARTRLLSLENTIGGKVLPQTYLANAQALAFQRG
LKIHLDGARVANAAVAQGIGIADIAGHFDSVSICLSKGLCAPVGSLLLGDERLIKKATRWRKMLGGGMRQAGILAAAGKL
ALIEQVERLGEDHENAAYLAQQLSQLSEFEIDLAAVQTNMVFANLATNVDEKALAKRCREAGIIISPGRTLRFVTHKDVS
RQDIDKVLQVFKLHLQA

Sequences:

>Translated_337_residues
MIDLRSDTVTQPTEAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTASGTQANLLALMAHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLTNQLDGTIALTDIEAAIKPDDIHFARTRLLSLENTIGGKVLPQTYLANAQALAFQRG
LKIHLDGARVANAAVAQGIGIADIAGHFDSVSICLSKGLCAPVGSLLLGDERLIKKATRWRKMLGGGMRQAGILAAAGKL
ALIEQVERLGEDHENAAYLAQQLSQLSEFEIDLAAVQTNMVFANLATNVDEKALAKRCREAGIIISPGRTLRFVTHKDVS
RQDIDKVLQVFKLHLQA
>Mature_337_residues
MIDLRSDTVTQPTEAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTASGTQANLLALMAHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLTNQLDGTIALTDIEAAIKPDDIHFARTRLLSLENTIGGKVLPQTYLANAQALAFQRG
LKIHLDGARVANAAVAQGIGIADIAGHFDSVSICLSKGLCAPVGSLLLGDERLIKKATRWRKMLGGGMRQAGILAAAGKL
ALIEQVERLGEDHENAAYLAQQLSQLSEFEIDLAAVQTNMVFANLATNVDEKALAKRCREAGIIISPGRTLRFVTHKDVS
RQDIDKVLQVFKLHLQA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. L-threo-phenylserine and L- erythro-phenylserine are also good substrates [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=335, Percent_Identity=56.1194029850746, Blast_Score=368, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI193206522, Length=345, Percent_Identity=42.3188405797101, Blast_Score=248, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI193206520, Length=345, Percent_Identity=42.3188405797101, Blast_Score=248, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI193206524, Length=345, Percent_Identity=42.3188405797101, Blast_Score=248, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6320789, Length=331, Percent_Identity=38.9728096676737, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21355439, Length=298, Percent_Identity=47.6510067114094, Blast_Score=259, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 36254; Mature: 36254

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLRSDTVTQPTEAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTASGTQ
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHEECCCCH
ANLLALMAHCERGDEYLCGQQAHNYKFEGGGAAVLGSIQPQPLTNQLDGTIALTDIEAAI
HHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCEEEEEEEHHHC
KPDDIHFARTRLLSLENTIGGKVLPQTYLANAQALAFQRGLKIHLDGARVANAAVAQGIG
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHHHCCCEEEECCHHHHHHHHHCCCC
IADIAGHFDSVSICLSKGLCAPVGSLLLGDERLIKKATRWRKMLGGGMRQAGILAAAGKL
HHHHHCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALIEQVERLGEDHENAAYLAQQLSQLSEFEIDLAAVQTNMVFANLATNVDEKALAKRCRE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGIIISPGRTLRFVTHKDVSRQDIDKVLQVFKLHLQA
CCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDLRSDTVTQPTEAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTASGTQ
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHEECCCCH
ANLLALMAHCERGDEYLCGQQAHNYKFEGGGAAVLGSIQPQPLTNQLDGTIALTDIEAAI
HHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCEEEEEEEHHHC
KPDDIHFARTRLLSLENTIGGKVLPQTYLANAQALAFQRGLKIHLDGARVANAAVAQGIG
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHHHCCCEEEECCHHHHHHHHHCCCC
IADIAGHFDSVSICLSKGLCAPVGSLLLGDERLIKKATRWRKMLGGGMRQAGILAAAGKL
HHHHHCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALIEQVERLGEDHENAAYLAQQLSQLSEFEIDLAAVQTNMVFANLATNVDEKALAKRCRE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGIIISPGRTLRFVTHKDVSRQDIDKVLQVFKLHLQA
CCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]