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The map label for this gene is aer [H]

Identifier: 117919599

GI number: 117919599

Start: 1356690

End: 1358258

Strand: Direct

Name: aer [H]

Synonym: Shewana3_1150

Alternate gene names: 117919599

Gene position: 1356690-1358258 (Clockwise)

Preceding gene: 117919593

Following gene: 117919600

Centisome position: 27.29

GC content: 51.5

Gene sequence:

>1569_bases
ATGCAAACACATTCAAAAAATGGTGAAAAACACCTATCCGAAAACGCTATTCTCCTCTCGACGACCGATCTGAAAGGCAA
CATTAAGTATGTTAATCAAACCTTTTCGCAGATCAGTGAATATAGCGTTGCCGAGTTGCAGGGGAGCCCGCACAACATAG
TGCGCCATGGTGATATGCCATCAGCCGCCTTTAAAATGCTTTGGGAGCGGATAAGAAGCGGCAAACCTTGGATGGGGATT
GTCAAAAATAGAACAAAAAACGGTGGCTATTACTGGGTGAATGCCTACGTCGCCCCAGTGTACGAAAATGGCAAAATTCA
TGAATATCAATCCGTTCGCCGCCAAGCAACGCCAGAACAAATCAAGGCGGCCGAGGAAATCTACCAAGGGATCAATCAAG
GACAACAGCCCAAGGCGCTGAAAAAAGACCGCTTAGGATTTCGCGGAAAAATACTCATGGCGATGTTGTTTACCATCGCT
CTAACCGCTTACTTGGCAACGTATTCGCCCATTTTAGCCGCCCTTGCTGGTGGACTGCTTGCCTTGGGTCTGTGGTACAT
GCTCATGCAACCCTTTCAGGCATTAGTGCAGGTGGCCAGCAATATTATCGATGATCCCGTTGCTATGGGGGTTTACACCG
GCAGGCAGGATGAAATCGGTAAGCTAGATCTGGCGCTGCGTTTTTTGATCACCGAAATTGGCGGCGTAGTGGGCCGAATG
GCGGACTCTGCCAGTGAGATCCAAGAGCAGAGCGTGAATCTTAAACAAACTATCACCAATACATGGGAGCATGCCGATAG
CCAGAGCGCGCAAACCACGCAGGCGGCAACGGCGATGGAGCAAATGAGCGCCAGCTTTGCCGAGGTAACGGATAATATCC
ATCGCACCGCATCCGAGATGGTTTCTAGCCATGAGGCGGCGCAGCGCGGTCATTCACGGCTTGAAACCGTTATCGAGGCG
ATACATCAACTGAGTGTGCAGGTGAGCCATTTCTCCGATGTGGTGCAAACGATTGAGCAGGACAGCCAAGCGATTCATCA
AGTGCTAGAAGTGATCCGCGCGATTGCCGATCAAACCAATCTGTTAGCGCTGAATGCCGCGATTGAAGCGGCGCGGGCAG
GGGAAAGCGGTCGCGGTTTTGCGGTCGTTGCCGATGAAGTCCGGCAGTTATCTAGCCGAACCAGTCAGTCGACCTCACAA
ATTGAGCTGATTGTAAGCCGCTTTAAAGACAGCACACAAAAAGCAACCTCAACCATGACGGCCGGACAGGAACAGGTTAA
GCGCTCTGTGTCCTTGGCGCAGGATGCCAGCATTGCCTTTGGCGAGTTGTTATCTTCTATCGCTCGCATCAATTCCTTAA
GTGATGACAATGCCGCAGCCATGACGCAGCAGGCATCGGTGGCGGCGGAAATCAGTCGAGCCATCCATGTGATCAGCGAT
TTGGCGCAGCAGAGTTTAGAGCAGACACAGGATGCGGCGGCGAGGGGCGATCAGGTTTCGCGCTTATCCACTAAAACCCA
CCATCTGTCGCAGCAATTTTGGCAGCAGAGCGTACAACGTAAGTATTAA

Upstream 100 bases:

>100_bases
TTAATTTTTATGCTGTCACTGTGAGCTTAATCAAAGCAGGCGTTCTGTGCTTTTGGCAAAATGCGGCGCAACTTTCACAT
GGAATCCGTTAGTGCGCCCT

Downstream 100 bases:

>100_bases
CCATTGTTATTTGATTGGTTGGTTTATATTTTTTGTTGCTGATTATAAATCAACCAGTTAGCTGTTTTTTAAGTTCCCTT
CGCGTGTCATTTCTTTGATA

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MQTHSKNGEKHLSENAILLSTTDLKGNIKYVNQTFSQISEYSVAELQGSPHNIVRHGDMPSAAFKMLWERIRSGKPWMGI
VKNRTKNGGYYWVNAYVAPVYENGKIHEYQSVRRQATPEQIKAAEEIYQGINQGQQPKALKKDRLGFRGKILMAMLFTIA
LTAYLATYSPILAALAGGLLALGLWYMLMQPFQALVQVASNIIDDPVAMGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQEQSVNLKQTITNTWEHADSQSAQTTQAATAMEQMSASFAEVTDNIHRTASEMVSSHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEQDSQAIHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQ
IELIVSRFKDSTQKATSTMTAGQEQVKRSVSLAQDASIAFGELLSSIARINSLSDDNAAAMTQQASVAAEISRAIHVISD
LAQQSLEQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY

Sequences:

>Translated_522_residues
MQTHSKNGEKHLSENAILLSTTDLKGNIKYVNQTFSQISEYSVAELQGSPHNIVRHGDMPSAAFKMLWERIRSGKPWMGI
VKNRTKNGGYYWVNAYVAPVYENGKIHEYQSVRRQATPEQIKAAEEIYQGINQGQQPKALKKDRLGFRGKILMAMLFTIA
LTAYLATYSPILAALAGGLLALGLWYMLMQPFQALVQVASNIIDDPVAMGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQEQSVNLKQTITNTWEHADSQSAQTTQAATAMEQMSASFAEVTDNIHRTASEMVSSHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEQDSQAIHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQ
IELIVSRFKDSTQKATSTMTAGQEQVKRSVSLAQDASIAFGELLSSIARINSLSDDNAAAMTQQASVAAEISRAIHVISD
LAQQSLEQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
>Mature_522_residues
MQTHSKNGEKHLSENAILLSTTDLKGNIKYVNQTFSQISEYSVAELQGSPHNIVRHGDMPSAAFKMLWERIRSGKPWMGI
VKNRTKNGGYYWVNAYVAPVYENGKIHEYQSVRRQATPEQIKAAEEIYQGINQGQQPKALKKDRLGFRGKILMAMLFTIA
LTAYLATYSPILAALAGGLLALGLWYMLMQPFQALVQVASNIIDDPVAMGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQEQSVNLKQTITNTWEHADSQSAQTTQAATAMEQMSASFAEVTDNIHRTASEMVSSHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEQDSQAIHQVLEVIRAIADQTNLLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQ
IELIVSRFKDSTQKATSTMTAGQEQVKRSVSLAQDASIAFGELLSSIARINSLSDDNAAAMTQQASVAAEISRAIHVISD
LAQQSLEQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=511, Percent_Identity=32.2896281800391, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI2367378, Length=339, Percent_Identity=27.4336283185841, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787690, Length=404, Percent_Identity=28.7128712871287, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788194, Length=340, Percent_Identity=30.2941176470588, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=25.5737704918033, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57319; Mature: 57319

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTHSKNGEKHLSENAILLSTTDLKGNIKYVNQTFSQISEYSVAELQGSPHNIVRHGDMP
CCCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCC
SAAFKMLWERIRSGKPWMGIVKNRTKNGGYYWVNAYVAPVYENGKIHEYQSVRRQATPEQ
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHCCHHH
IKAAEEIYQGINQGQQPKALKKDRLGFRGKILMAMLFTIALTAYLATYSPILAALAGGLL
HHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLWYMLMQPFQALVQVASNIIDDPVAMGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
ADSASEIQEQSVNLKQTITNTWEHADSQSAQTTQAATAMEQMSASFAEVTDNIHRTASEM
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSHEAAQRGHSRLETVIEAIHQLSVQVSHFSDVVQTIEQDSQAIHQVLEVIRAIADQTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQIELIVSRFKDSTQKATSTMT
EEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQEQVKRSVSLAQDASIAFGELLSSIARINSLSDDNAAAMTQQASVAAEISRAIHVISD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQQSLEQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTHSKNGEKHLSENAILLSTTDLKGNIKYVNQTFSQISEYSVAELQGSPHNIVRHGDMP
CCCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCC
SAAFKMLWERIRSGKPWMGIVKNRTKNGGYYWVNAYVAPVYENGKIHEYQSVRRQATPEQ
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHCCHHH
IKAAEEIYQGINQGQQPKALKKDRLGFRGKILMAMLFTIALTAYLATYSPILAALAGGLL
HHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLWYMLMQPFQALVQVASNIIDDPVAMGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
ADSASEIQEQSVNLKQTITNTWEHADSQSAQTTQAATAMEQMSASFAEVTDNIHRTASEM
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSHEAAQRGHSRLETVIEAIHQLSVQVSHFSDVVQTIEQDSQAIHQVLEVIRAIADQTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLALNAAIEAARAGESGRGFAVVADEVRQLSSRTSQSTSQIELIVSRFKDSTQKATSTMT
EEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQEQVKRSVSLAQDASIAFGELLSSIARINSLSDDNAAAMTQQASVAAEISRAIHVISD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQQSLEQTQDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]