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The map label for this gene is ydhC [C]

Identifier: 117919531

GI number: 117919531

Start: 1269794

End: 1270972

Strand: Direct

Name: ydhC [C]

Synonym: Shewana3_1082

Alternate gene names: 117919531

Gene position: 1269794-1270972 (Clockwise)

Preceding gene: 117919528

Following gene: 117919536

Centisome position: 25.54

GC content: 47.24

Gene sequence:

>1179_bases
ATGAAAATAAAACCACCACTCTGGCTGTGCGTACTCTTGATGATGTTTCCGCAAATTATGGAAACCATCTATAGCCCTGC
GTTGCCTAATATTGCAGAAAATTTTGCGGTGTCTGTTACCAGCGCCTCGCAGACTTTATCTGTGTACTTTATCGCTTTTG
CTGTAGGCGTATTTTGCTGGGGTCGTTTAGCCGACATCATTGGTCGCCGCAATGCCATGCTTGCGGGCTTACTCTGTTAT
GCCATTGGTTCCGCATGCGCGTTGATGATTAGCGACTTTACCCTGTTGTTGTTCGCTCGGGTATTATCGGCCTTTGGTGC
AGCAGTGGGTTCTGTCATCACTCAAACCATGATGCGTGACAGTTACAACGGGGAGGAACTCGCGAAAGTCTTTTCGGTGA
TGGGCATGTCTCTTGGGATTAGTCCCATTATCGGATTGCTATTGGGGAGCATCCTCAGTGCTTATTGGGGATATCAAGGG
GTATTTGTCGCCCTGATGGTTTCTGCCATTGTGTTGTTGTTTTTGTCGGTAAAATCTTTGCCCGAAACCAAGCCTGAACA
CACTCAAAAAATCGCGATAGTTGAATTAGCTATCAAGATGCTTACCGACATTGGGATAATTAAAAATACTCTGCTGGTGG
CCTCATTTAACTTGATGTGGTTTAGCTACTTTTCGCTGGCACCATTTATGTTTGAGGCGCGAGGATTGTCGACGCTTGCC
TTCGGTGCCAGTGGGTTGTTATTGGGCTTTGGCGCATTCCTTGGCAGTTATTTTAATAAACTATTGCTGGGTAGAGGCTA
TTCCTGTGCGCTATTAGTGCGGTTAGCAAGCCTTATGGCACTATTCGGAGGACTCGGTATTTGGCTGTTCCAATCGACTA
ATATTGGCTTGAATAATGTTTATTTCTTACTACCCATGCTGTTGATTGTGATTGCTTATGGGATCGCGATTCCTAATATC
CTGAGCTCGGCGCTGGCAAACTACCGCGCTTATGCAGGTTCCGCGGGTGCACTGTTTGGACTGTTTTATTACATTCTGTT
GGGGCTAGGTTTAGGCGGTGCGGGCATGGTAAGCCATCTTGGGGGCGTTATTACCTTAGCTGCACTGCTATGTGTTGGGC
TTGGATATGCGGGTTTGGCAGGCAGGACAGTGCTAAGAGGGAAGTCGTCTCGAGCGTAA

Upstream 100 bases:

>100_bases
TCACTTAGGGATCCTATCTATACTGCGCCCTCTTTGACAAGTATGGAGCGCCGTTTTGGTTTATCGGTTAACCCTGAAAG
CTAAAACGTAGATAAAAATC

Downstream 100 bases:

>100_bases
ATAAAAAGCCAAGGGTGATTCCCTTGGCTTTATGGTTTTAACAAACCTTATGCCGTTTCGCTTTACTGTCTCGTGCTAGG
CTTTAGCAGTGTGTTCCTGT

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKIKPPLWLCVLLMMFPQIMETIYSPALPNIAENFAVSVTSASQTLSVYFIAFAVGVFCWGRLADIIGRRNAMLAGLLCY
AIGSACALMISDFTLLLFARVLSAFGAAVGSVITQTMMRDSYNGEELAKVFSVMGMSLGISPIIGLLLGSILSAYWGYQG
VFVALMVSAIVLLFLSVKSLPETKPEHTQKIAIVELAIKMLTDIGIIKNTLLVASFNLMWFSYFSLAPFMFEARGLSTLA
FGASGLLLGFGAFLGSYFNKLLLGRGYSCALLVRLASLMALFGGLGIWLFQSTNIGLNNVYFLLPMLLIVIAYGIAIPNI
LSSALANYRAYAGSAGALFGLFYYILLGLGLGGAGMVSHLGGVITLAALLCVGLGYAGLAGRTVLRGKSSRA

Sequences:

>Translated_392_residues
MKIKPPLWLCVLLMMFPQIMETIYSPALPNIAENFAVSVTSASQTLSVYFIAFAVGVFCWGRLADIIGRRNAMLAGLLCY
AIGSACALMISDFTLLLFARVLSAFGAAVGSVITQTMMRDSYNGEELAKVFSVMGMSLGISPIIGLLLGSILSAYWGYQG
VFVALMVSAIVLLFLSVKSLPETKPEHTQKIAIVELAIKMLTDIGIIKNTLLVASFNLMWFSYFSLAPFMFEARGLSTLA
FGASGLLLGFGAFLGSYFNKLLLGRGYSCALLVRLASLMALFGGLGIWLFQSTNIGLNNVYFLLPMLLIVIAYGIAIPNI
LSSALANYRAYAGSAGALFGLFYYILLGLGLGGAGMVSHLGGVITLAALLCVGLGYAGLAGRTVLRGKSSRA
>Mature_392_residues
MKIKPPLWLCVLLMMFPQIMETIYSPALPNIAENFAVSVTSASQTLSVYFIAFAVGVFCWGRLADIIGRRNAMLAGLLCY
AIGSACALMISDFTLLLFARVLSAFGAAVGSVITQTMMRDSYNGEELAKVFSVMGMSLGISPIIGLLLGSILSAYWGYQG
VFVALMVSAIVLLFLSVKSLPETKPEHTQKIAIVELAIKMLTDIGIIKNTLLVASFNLMWFSYFSLAPFMFEARGLSTLA
FGASGLLLGFGAFLGSYFNKLLLGRGYSCALLVRLASLMALFGGLGIWLFQSTNIGLNNVYFLLPMLLIVIAYGIAIPNI
LSSALANYRAYAGSAGALFGLFYYILLGLGLGGAGMVSHLGGVITLAALLCVGLGYAGLAGRTVLRGKSSRA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=322, Percent_Identity=27.0186335403727, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082312, Length=332, Percent_Identity=26.2048192771084, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788509, Length=189, Percent_Identity=29.1005291005291, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790146, Length=174, Percent_Identity=28.1609195402299, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41728; Mature: 41728

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKPPLWLCVLLMMFPQIMETIYSPALPNIAENFAVSVTSASQTLSVYFIAFAVGVFCW
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEECHHHHHHHHHHHHHHHHHHH
GRLADIIGRRNAMLAGLLCYAIGSACALMISDFTLLLFARVLSAFGAAVGSVITQTMMRD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SYNGEELAKVFSVMGMSLGISPIIGLLLGSILSAYWGYQGVFVALMVSAIVLLFLSVKSL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
PETKPEHTQKIAIVELAIKMLTDIGIIKNTLLVASFNLMWFSYFSLAPFMFEARGLSTLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FGASGLLLGFGAFLGSYFNKLLLGRGYSCALLVRLASLMALFGGLGIWLFQSTNIGLNNV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHEEECCCCCHHHH
YFLLPMLLIVIAYGIAIPNILSSALANYRAYAGSAGALFGLFYYILLGLGLGGAGMVSHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
GGVITLAALLCVGLGYAGLAGRTVLRGKSSRA
HHHHHHHHHHHHHCCCCHHCCCHHHCCCCCCC
>Mature Secondary Structure
MKIKPPLWLCVLLMMFPQIMETIYSPALPNIAENFAVSVTSASQTLSVYFIAFAVGVFCW
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEECHHHHHHHHHHHHHHHHHHH
GRLADIIGRRNAMLAGLLCYAIGSACALMISDFTLLLFARVLSAFGAAVGSVITQTMMRD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SYNGEELAKVFSVMGMSLGISPIIGLLLGSILSAYWGYQGVFVALMVSAIVLLFLSVKSL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
PETKPEHTQKIAIVELAIKMLTDIGIIKNTLLVASFNLMWFSYFSLAPFMFEARGLSTLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FGASGLLLGFGAFLGSYFNKLLLGRGYSCALLVRLASLMALFGGLGIWLFQSTNIGLNNV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHEEECCCCCHHHH
YFLLPMLLIVIAYGIAIPNILSSALANYRAYAGSAGALFGLFYYILLGLGLGGAGMVSHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
GGVITLAALLCVGLGYAGLAGRTVLRGKSSRA
HHHHHHHHHHHHHCCCCHHCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA