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The map label for this gene is sufS [H]

Identifier: 117919260

GI number: 117919260

Start: 931790

End: 933037

Strand: Reverse

Name: sufS [H]

Synonym: Shewana3_0808

Alternate gene names: 117919260

Gene position: 933037-931790 (Counterclockwise)

Preceding gene: 117919262

Following gene: 117919259

Centisome position: 18.77

GC content: 52.48

Gene sequence:

>1248_bases
ATGACACACTCAGCCTCGACCGACACAGCATTGCCCGATAGCCATAACCAAATCCGCGCGCAATTTCCTACCCTCTCGCA
AATGTTGGGCGATTATCCCCTGTGTTATCTCGATACTGCGGCCACCAGCCAAAAGCCGCAATCCGTGTTAGATGCCATGG
CGCAGTATTACCTGAACGACAATGCCAATGTGCACCGCGCGGCGCACCAATTGTCGGCGCGCGCGACTTCTAGCTACGAG
AAGGTTCGCGATGACTTACAAGGGTTTATTAATGCTAAACGCCGCGAAGAAATCATCTTCACCCATGGCACCACTGAGTC
GATCAATCTAGTTGCCTATGGCTTAACGCCACAGATAGCAGCGGGCGATCTGATTTTGATCGATACCGCCGCCCACCACG
CCAACATAGTGCCGTGGCAAGAATTGGCAAAACGCACGGGTGCCATCATTAAACCTATTCCTCTCGATCAGGATGGCAGG
CTCGATCGCCATGCCTATCAAGCACTGCTCACCCTCAAGCCAAAGGTAGTTGCCCTTTGCCATGTGTCGAACGCCTTAGG
CACAGTGAATCCTGTTGTCGAGTTAGTACAGCAAGCCAAGGCGCAGGGGGCGCTCACCTTAGTCGATGGAGCACAGGCGG
TTGCACACTTAAACTTAGATATGGCCGCCATCGATTGTGATTTTTATGTGTTTTCAGGCCATAAGATGTATGGTCCAACT
GGCATTGGTGTGCTTTATGGCCGCTTCGATAAGTTAGATACGCTCACCCCGCTGTTAACGGGCGGCGAGATGATTAAACG
AGTGAGTTTCGATGGCACAGAATTTGGCAGTTTACCTAATCGCTTAGAGGCAGGCACCCCGCCCATCAGTGAAGTCATCG
GCCTAGGCGCCGCTATCCGCTTTTTGCAACAACACTTAACGCCAGCGGTTCAGGCCCATGAGGCAGAACTACTGCAGTAT
TTACAGCAGCAGCTGCGCGCCCTCGGAGATGTGCATCTCTATGCTGCCCATAGTGATAATCTCGGTGCTGTCGCCTTTAA
TCTGGGTGATGAACATCATCAAGATGTGGGGATTTTATTAGACCAACAAGGCGTTGCCGTGCGCTGCGGCCATCACTGCG
CCATGCCCTTGATGCAAAGCCTTAACCTGAAGGGCTGCTGCCGCGCATCGATTGGGATCTACACCAATAAAGCCGATATC
GACCGCTTTATTGCCGCCTTAGCCTCAGTCAAAGAGTTGCTGCTCTAA

Upstream 100 bases:

>100_bases
AACCACAGCAACAATAACGGGAAATTAGCCCGCGAAAACTTGCATTCGGCAGGGAGATAACCGAAGATCCCAAAGCCTTT
TTTATTGCGTAAAGCCCTAG

Downstream 100 bases:

>100_bases
TCCGCTCGCTAAGGGTTAATATCATTGCGCCATCAGGCAACATGCTTAAGAAGAGGACATTTTCCCCATGACATTGCCAA
TCATGCCCGCTGCCACCGAG

Product: cysteine desulfurase

Products: NA

Alternate protein names: Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTHSASTDTALPDSHNQIRAQFPTLSQMLGDYPLCYLDTAATSQKPQSVLDAMAQYYLNDNANVHRAAHQLSARATSSYE
KVRDDLQGFINAKRREEIIFTHGTTESINLVAYGLTPQIAAGDLILIDTAAHHANIVPWQELAKRTGAIIKPIPLDQDGR
LDRHAYQALLTLKPKVVALCHVSNALGTVNPVVELVQQAKAQGALTLVDGAQAVAHLNLDMAAIDCDFYVFSGHKMYGPT
GIGVLYGRFDKLDTLTPLLTGGEMIKRVSFDGTEFGSLPNRLEAGTPPISEVIGLGAAIRFLQQHLTPAVQAHEAELLQY
LQQQLRALGDVHLYAAHSDNLGAVAFNLGDEHHQDVGILLDQQGVAVRCGHHCAMPLMQSLNLKGCCRASIGIYTNKADI
DRFIAALASVKELLL

Sequences:

>Translated_415_residues
MTHSASTDTALPDSHNQIRAQFPTLSQMLGDYPLCYLDTAATSQKPQSVLDAMAQYYLNDNANVHRAAHQLSARATSSYE
KVRDDLQGFINAKRREEIIFTHGTTESINLVAYGLTPQIAAGDLILIDTAAHHANIVPWQELAKRTGAIIKPIPLDQDGR
LDRHAYQALLTLKPKVVALCHVSNALGTVNPVVELVQQAKAQGALTLVDGAQAVAHLNLDMAAIDCDFYVFSGHKMYGPT
GIGVLYGRFDKLDTLTPLLTGGEMIKRVSFDGTEFGSLPNRLEAGTPPISEVIGLGAAIRFLQQHLTPAVQAHEAELLQY
LQQQLRALGDVHLYAAHSDNLGAVAFNLGDEHHQDVGILLDQQGVAVRCGHHCAMPLMQSLNLKGCCRASIGIYTNKADI
DRFIAALASVKELLL
>Mature_414_residues
THSASTDTALPDSHNQIRAQFPTLSQMLGDYPLCYLDTAATSQKPQSVLDAMAQYYLNDNANVHRAAHQLSARATSSYEK
VRDDLQGFINAKRREEIIFTHGTTESINLVAYGLTPQIAAGDLILIDTAAHHANIVPWQELAKRTGAIIKPIPLDQDGRL
DRHAYQALLTLKPKVVALCHVSNALGTVNPVVELVQQAKAQGALTLVDGAQAVAHLNLDMAAIDCDFYVFSGHKMYGPTG
IGVLYGRFDKLDTLTPLLTGGEMIKRVSFDGTEFGSLPNRLEAGTPPISEVIGLGAAIRFLQQHLTPAVQAHEAELLQYL
QQQLRALGDVHLYAAHSDNLGAVAFNLGDEHHQDVGILLDQQGVAVRCGHHCAMPLMQSLNLKGCCRASIGIYTNKADID
RFIAALASVKELLL

Specific function: Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=377, Percent_Identity=26.525198938992, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI156713448, Length=322, Percent_Identity=26.3975155279503, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1787970, Length=403, Percent_Identity=47.1464019851117, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1789175, Length=400, Percent_Identity=39, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI48994898, Length=389, Percent_Identity=25.4498714652956, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25143064, Length=287, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193211090, Length=376, Percent_Identity=22.3404255319149, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=399, Percent_Identity=25.062656641604, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI20129463, Length=297, Percent_Identity=29.96632996633, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7; =4.4.1.16 [H]

Molecular weight: Translated: 45005; Mature: 44874

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSASTDTALPDSHNQIRAQFPTLSQMLGDYPLCYLDTAATSQKPQSVLDAMAQYYLND
CCCCCCCCCCCCCCCCHHHCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCC
NANVHRAAHQLSARATSSYEKVRDDLQGFINAKRREEIIFTHGTTESINLVAYGLTPQIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCC
AGDLILIDTAAHHANIVPWQELAKRTGAIIKPIPLDQDGRLDRHAYQALLTLKPKVVALC
CCCEEEEECCCCCCCCCCHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEE
HVSNALGTVNPVVELVQQAKAQGALTLVDGAQAVAHLNLDMAAIDCDFYVFSGHKMYGPT
EHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHCCCEEEEEEEEEEEEECCEEECCC
GIGVLYGRFDKLDTLTPLLTGGEMIKRVSFDGTEFGSLPNRLEAGTPPISEVIGLGAAIR
CHHHHHHCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FLQQHLTPAVQAHEAELLQYLQQQLRALGDVHLYAAHSDNLGAVAFNLGDEHHQDVGILL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCCCCCEEEE
DQQGVAVRCGHHCAMPLMQSLNLKGCCRASIGIYTNKADIDRFIAALASVKELLL
ECCCCEEECCCHHHHHHHHCCCCCCCEECCCCEEECHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
THSASTDTALPDSHNQIRAQFPTLSQMLGDYPLCYLDTAATSQKPQSVLDAMAQYYLND
CCCCCCCCCCCCCCCHHHCCCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCC
NANVHRAAHQLSARATSSYEKVRDDLQGFINAKRREEIIFTHGTTESINLVAYGLTPQIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCC
AGDLILIDTAAHHANIVPWQELAKRTGAIIKPIPLDQDGRLDRHAYQALLTLKPKVVALC
CCCEEEEECCCCCCCCCCHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEE
HVSNALGTVNPVVELVQQAKAQGALTLVDGAQAVAHLNLDMAAIDCDFYVFSGHKMYGPT
EHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHCCCEEEEEEEEEEEEECCEEECCC
GIGVLYGRFDKLDTLTPLLTGGEMIKRVSFDGTEFGSLPNRLEAGTPPISEVIGLGAAIR
CHHHHHHCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FLQQHLTPAVQAHEAELLQYLQQQLRALGDVHLYAAHSDNLGAVAFNLGDEHHQDVGILL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCCCCCEEEE
DQQGVAVRCGHHCAMPLMQSLNLKGCCRASIGIYTNKADIDRFIAALASVKELLL
ECCCCEEECCCHHHHHHHHCCCCCCCEECCCCEEECHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA