Click here to switch to the map view.

The map label for this gene is panE [H]

Identifier: 117919232

GI number: 117919232

Start: 902585

End: 903568

Strand: Reverse

Name: panE [H]

Synonym: Shewana3_0780

Alternate gene names: 117919232

Gene position: 903568-902585 (Counterclockwise)

Preceding gene: 117919233

Following gene: 117919231

Centisome position: 18.17

GC content: 51.93

Gene sequence:

>984_bases
ATGTTCGGCCAAGGTGCGTCATCGACTGTAGAGTCTCAAGTCACCGATATCGCGATTTTAGGTGCTGGCGCCGTGGGACA
ATTGATTTGTCATCAACTGCATTCGACGGGGTTAGCCGTAGGCTTGATAGCGCGTGAGACCTCTGCATCCACCTCTGAGG
CGACGGATTGGCAAGACCTCGTGTTTTGCCCTCTGCCATCAACGGATGCTGATACCGACTCAGTGTCATACCGAGTGCCA
ACATTTAGTCTAGACGGCACAAGCTTACTGCAGATCAGGCTGCTAATTGTGTGCGTTAAGGCTTATCAAGTCATTGATGC
CATTAGCCCTTTACTCGACAAACTCTCGCCCCAGTGTCATATCCTGTTACTGCATAATGGCATGGGTCCACACTTGGCAC
TGGCGCCCAAATTACAGGGTCGTGGCTTAAGCCTTGGTACTACCTCCCAAGGCGTGATGCGCCAGTCCCGCTGGCAAATC
AAACAAACTGGCCAAGGCTTAACCCAGTTTGGCCACTTTATCGGCCCCGCATTACCGCAAGCACTGCGTGACGGGCTGCT
CAACGCTATCCCCAACAGTGAATGGGTTGAGGCAATAATCCCTAGTCTTTGGCAAAAGCTCGCGGTAAACGCTGCAATTA
ATCCCCTGACTGCCCTGCATCAATGTCCCAATGGCACATTGGCTCAGGCGCAATTTACCCAGACCATAACCAGTATCTTA
GATGAGCTGGTCGAGGTGGCCGCCCACGATGGCATAGCACTGGATAGACAAATGCTTGAAGAGCGCGCGTACCGGGTGAT
TGAACTCACGGCCGCGAATTTCTCGTCGATGCACCAAGATGTAGCACACCATAGGCCAACCGAGATTGAACAAATTAATG
GTTATATTTGCGACCGCGCCAGCGCGCACGGTTTAAGTGCAGCAACCAATGCCCAAATGTGCCAAGCCATTAAACAGTTG
TCGGCAATAACACCACAAGCTTAA

Upstream 100 bases:

>100_bases
TGGGCGACGTGTTAGCGGACTTTGCGGGTATCGCTTTGTTTTACTTCTGTCTTTGGGCCTATCGAAAATACTTTAGCGCC
GCCCAACTCAAGGAAGAATA

Downstream 100 bases:

>100_bases
TCAATATACTCAATTGATTTTAAATGGATTTACCCATATCCAACCGAGCCAAATAAAACTCGGCGATATTCCAGCATTTT
TAAATGCACTCGAATTGGCA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MFGQGASSTVESQVTDIAILGAGAVGQLICHQLHSTGLAVGLIARETSASTSEATDWQDLVFCPLPSTDADTDSVSYRVP
TFSLDGTSLLQIRLLIVCVKAYQVIDAISPLLDKLSPQCHILLLHNGMGPHLALAPKLQGRGLSLGTTSQGVMRQSRWQI
KQTGQGLTQFGHFIGPALPQALRDGLLNAIPNSEWVEAIIPSLWQKLAVNAAINPLTALHQCPNGTLAQAQFTQTITSIL
DELVEVAAHDGIALDRQMLEERAYRVIELTAANFSSMHQDVAHHRPTEIEQINGYICDRASAHGLSAATNAQMCQAIKQL
SAITPQA

Sequences:

>Translated_327_residues
MFGQGASSTVESQVTDIAILGAGAVGQLICHQLHSTGLAVGLIARETSASTSEATDWQDLVFCPLPSTDADTDSVSYRVP
TFSLDGTSLLQIRLLIVCVKAYQVIDAISPLLDKLSPQCHILLLHNGMGPHLALAPKLQGRGLSLGTTSQGVMRQSRWQI
KQTGQGLTQFGHFIGPALPQALRDGLLNAIPNSEWVEAIIPSLWQKLAVNAAINPLTALHQCPNGTLAQAQFTQTITSIL
DELVEVAAHDGIALDRQMLEERAYRVIELTAANFSSMHQDVAHHRPTEIEQINGYICDRASAHGLSAATNAQMCQAIKQL
SAITPQA
>Mature_327_residues
MFGQGASSTVESQVTDIAILGAGAVGQLICHQLHSTGLAVGLIARETSASTSEATDWQDLVFCPLPSTDADTDSVSYRVP
TFSLDGTSLLQIRLLIVCVKAYQVIDAISPLLDKLSPQCHILLLHNGMGPHLALAPKLQGRGLSLGTTSQGVMRQSRWQI
KQTGQGLTQFGHFIGPALPQALRDGLLNAIPNSEWVEAIIPSLWQKLAVNAAINPLTALHQCPNGTLAQAQFTQTITSIL
DELVEVAAHDGIALDRQMLEERAYRVIELTAANFSSMHQDVAHHRPTEIEQINGYICDRASAHGLSAATNAQMCQAIKQL
SAITPQA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=317, Percent_Identity=33.7539432176656, Blast_Score=133, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 35034; Mature: 35034

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGQGASSTVESQVTDIAILGAGAVGQLICHQLHSTGLAVGLIARETSASTSEATDWQDL
CCCCCCCHHHHHHHHHEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCE
VFCPLPSTDADTDSVSYRVPTFSLDGTSLLQIRLLIVCVKAYQVIDAISPLLDKLSPQCH
EEECCCCCCCCCCCCEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ILLLHNGMGPHLALAPKLQGRGLSLGTTSQGVMRQSRWQIKQTGQGLTQFGHFIGPALPQ
EEEEECCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ALRDGLLNAIPNSEWVEAIIPSLWQKLAVNAAINPLTALHQCPNGTLAQAQFTQTITSIL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DELVEVAAHDGIALDRQMLEERAYRVIELTAANFSSMHQDVAHHRPTEIEQINGYICDRA
HHHHHHHHCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
SAHGLSAATNAQMCQAIKQLSAITPQA
CCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFGQGASSTVESQVTDIAILGAGAVGQLICHQLHSTGLAVGLIARETSASTSEATDWQDL
CCCCCCCHHHHHHHHHEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCE
VFCPLPSTDADTDSVSYRVPTFSLDGTSLLQIRLLIVCVKAYQVIDAISPLLDKLSPQCH
EEECCCCCCCCCCCCEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ILLLHNGMGPHLALAPKLQGRGLSLGTTSQGVMRQSRWQIKQTGQGLTQFGHFIGPALPQ
EEEEECCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ALRDGLLNAIPNSEWVEAIIPSLWQKLAVNAAINPLTALHQCPNGTLAQAQFTQTITSIL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DELVEVAAHDGIALDRQMLEERAYRVIELTAANFSSMHQDVAHHRPTEIEQINGYICDRA
HHHHHHHHCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
SAHGLSAATNAQMCQAIKQLSAITPQA
CCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]