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The map label for this gene is fabF [H]

Identifier: 117918786

GI number: 117918786

Start: 363111

End: 364328

Strand: Reverse

Name: fabF [H]

Synonym: Shewana3_0329

Alternate gene names: 117918786

Gene position: 364328-363111 (Counterclockwise)

Preceding gene: 117918787

Following gene: 117918785

Centisome position: 7.33

GC content: 55.09

Gene sequence:

>1218_bases
ATGAACAACAGAGTCGCCATTACACAAATTGGATTGTGTACCCCGTTAGGGCAAACGCCCGAGCAGGTGTTAGCCCGCTT
GATTGCAGGCGATACCAGTGCCATGCAAACCAGTGAAACCCTGCTATTTGAGGAGTCGACACTGGTTGCGCCCGTCACTG
AGTCGTTACCGACGATACCTGCCGCGCTGGCGCAATTCGATTGTCGCAATAATCAGTTGCTCCTTGCTGCCGCACTGCAA
ATTCGCGATGCCGTAGAGCAAGCCAAAGGTGAGTTTGGCGCCGACCGTATCGGCGTGGTCTTAGGCACCAGCACCTCGGG
AATTTCGAAAGGCGAAGCCGCCTTGGCCTATCGCAATCAACACGGCCACTTCCCCGCCGATTACCATTATTTCCAGCAGG
AACTCGGTAGCACCAGCGATTTTCTACGCCAGTTATTTGAGCTCCAAGGCCCTTGCTACACCATTTCGACCGCCTGCTCC
TCTAGCGCCAAGGTATTTGCCAGCGCCAAACGCCTACTCGAGGCCAAGCTGTGCGATATGGTGATCGTCGGCGGTATCGA
CAGCCTGTGCCAACTGACAGTCAACGGATTTCACGCCTTAGAATCGGTTTCCAAGGGACATTGCAACCCCTTCAGCGCCA
ACCGCGATGGCATCAATATCGGTGAAGGCGCCGCGCTATTTACTCTGACCTTAGCGACAGACAACACAGCAAATGAAGCC
TGCGTTTTGCTTGCAGGCATAGGCGAGTCGAGCGATGCGCACCATATGTCGGCGCCACATCCCGAAGGTGCGGGGGCAAT
TGCCGCCATGCAGGCCGCGCTTGATGATGCACAGATATCGGCGCAACAGATTGATTATATAAACTTACATGGTACAGCAA
CGCCTAAAAATGATGCGATGGAAAGCCGTGCCGTAGCCTCGGTATTTGGCGACACGCCGCCACCCGCAAGCTCAACCAAA
CCGCTGGTCGGCCATACCTTAGGTGCCGCGGGCGCGATTGAAGCCGCATTTTGTTATTTACTGCTCTCACCCCATAATCA
CCATCTTGCCCTGCCTCCCCACAGGTTTGATGGGCAGCCAGATCCACAGGATCCCAGCATAGCCTTAGTCGCGCCCAAAC
AATGTGCCGAGCATGGCAGGCTGAACTATGTGATGAGCAACTCCTTCGCCTTTGGCGGCAGCAATGCCTGCCTGATTTTT
TGCCGTAAAGGGGCTTAA

Upstream 100 bases:

>100_bases
TTAATCGTCTTTTGACAATGCCATAGGCACCCGTTAACAGCCAATCGATATGAGCCTTTAGCCTTGCTCACATCAAAGGC
CATAGGTATAGCAAGCAGCA

Downstream 100 bases:

>100_bases
GATTTATGTCCAGTTCTACTGACACTGCAATGGCACCCGCCGAGCCGATGTGGCTGCAACAATTAGCCGAGCAGAATATT
GCCGATTTTATTCCGCACCG

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MNNRVAITQIGLCTPLGQTPEQVLARLIAGDTSAMQTSETLLFEESTLVAPVTESLPTIPAALAQFDCRNNQLLLAAALQ
IRDAVEQAKGEFGADRIGVVLGTSTSGISKGEAALAYRNQHGHFPADYHYFQQELGSTSDFLRQLFELQGPCYTISTACS
SSAKVFASAKRLLEAKLCDMVIVGGIDSLCQLTVNGFHALESVSKGHCNPFSANRDGINIGEGAALFTLTLATDNTANEA
CVLLAGIGESSDAHHMSAPHPEGAGAIAAMQAALDDAQISAQQIDYINLHGTATPKNDAMESRAVASVFGDTPPPASSTK
PLVGHTLGAAGAIEAAFCYLLLSPHNHHLALPPHRFDGQPDPQDPSIALVAPKQCAEHGRLNYVMSNSFAFGGSNACLIF
CRKGA

Sequences:

>Translated_405_residues
MNNRVAITQIGLCTPLGQTPEQVLARLIAGDTSAMQTSETLLFEESTLVAPVTESLPTIPAALAQFDCRNNQLLLAAALQ
IRDAVEQAKGEFGADRIGVVLGTSTSGISKGEAALAYRNQHGHFPADYHYFQQELGSTSDFLRQLFELQGPCYTISTACS
SSAKVFASAKRLLEAKLCDMVIVGGIDSLCQLTVNGFHALESVSKGHCNPFSANRDGINIGEGAALFTLTLATDNTANEA
CVLLAGIGESSDAHHMSAPHPEGAGAIAAMQAALDDAQISAQQIDYINLHGTATPKNDAMESRAVASVFGDTPPPASSTK
PLVGHTLGAAGAIEAAFCYLLLSPHNHHLALPPHRFDGQPDPQDPSIALVAPKQCAEHGRLNYVMSNSFAFGGSNACLIF
CRKGA
>Mature_405_residues
MNNRVAITQIGLCTPLGQTPEQVLARLIAGDTSAMQTSETLLFEESTLVAPVTESLPTIPAALAQFDCRNNQLLLAAALQ
IRDAVEQAKGEFGADRIGVVLGTSTSGISKGEAALAYRNQHGHFPADYHYFQQELGSTSDFLRQLFELQGPCYTISTACS
SSAKVFASAKRLLEAKLCDMVIVGGIDSLCQLTVNGFHALESVSKGHCNPFSANRDGINIGEGAALFTLTLATDNTANEA
CVLLAGIGESSDAHHMSAPHPEGAGAIAAMQAALDDAQISAQQIDYINLHGTATPKNDAMESRAVASVFGDTPPPASSTK
PLVGHTLGAAGAIEAAFCYLLLSPHNHHLALPPHRFDGQPDPQDPSIALVAPKQCAEHGRLNYVMSNSFAFGGSNACLIF
CRKGA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=437, Percent_Identity=31.5789473684211, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI223972627, Length=216, Percent_Identity=37.5, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI41872631, Length=264, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787337, Length=272, Percent_Identity=36.7647058823529, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788663, Length=420, Percent_Identity=28.8095238095238, Blast_Score=132, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71983541, Length=408, Percent_Identity=26.2254901960784, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71983535, Length=262, Percent_Identity=28.6259541984733, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI212642053, Length=275, Percent_Identity=27.6363636363636, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320904, Length=452, Percent_Identity=26.3274336283186, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24644341, Length=421, Percent_Identity=29.6912114014252, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24581345, Length=266, Percent_Identity=25.187969924812, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42526; Mature: 42526

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRVAITQIGLCTPLGQTPEQVLARLIAGDTSAMQTSETLLFEESTLVAPVTESLPTIP
CCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCHHHCCCCEEEEECCEEEECHHHHCCHHH
AALAQFDCRNNQLLLAAALQIRDAVEQAKGEFGADRIGVVLGTSTSGISKGEAALAYRNQ
HHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEECC
HGHFPADYHYFQQELGSTSDFLRQLFELQGPCYTISTACSSSAKVFASAKRLLEAKLCDM
CCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCE
VIVGGIDSLCQLTVNGFHALESVSKGHCNPFSANRDGINIGEGAALFTLTLATDNTANEA
EEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCE
CVLLAGIGESSDAHHMSAPHPEGAGAIAAMQAALDDAQISAQQIDYINLHGTATPKNDAM
EEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCHHH
ESRAVASVFGDTPPPASSTKPLVGHTLGAAGAIEAAFCYLLLSPHNHHLALPPHRFDGQP
HHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHEEEEEECCCCCEEECCCCCCCCCC
DPQDPSIALVAPKQCAEHGRLNYVMSNSFAFGGSNACLIFCRKGA
CCCCCCEEEECCHHHHHCCCEEEEEECCEEECCCCEEEEEEECCC
>Mature Secondary Structure
MNNRVAITQIGLCTPLGQTPEQVLARLIAGDTSAMQTSETLLFEESTLVAPVTESLPTIP
CCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCHHHCCCCEEEEECCEEEECHHHHCCHHH
AALAQFDCRNNQLLLAAALQIRDAVEQAKGEFGADRIGVVLGTSTSGISKGEAALAYRNQ
HHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEECC
HGHFPADYHYFQQELGSTSDFLRQLFELQGPCYTISTACSSSAKVFASAKRLLEAKLCDM
CCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCE
VIVGGIDSLCQLTVNGFHALESVSKGHCNPFSANRDGINIGEGAALFTLTLATDNTANEA
EEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCE
CVLLAGIGESSDAHHMSAPHPEGAGAIAAMQAALDDAQISAQQIDYINLHGTATPKNDAM
EEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCHHH
ESRAVASVFGDTPPPASSTKPLVGHTLGAAGAIEAAFCYLLLSPHNHHLALPPHRFDGQP
HHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHEEEEEECCCCCEEECCCCCCCCCC
DPQDPSIALVAPKQCAEHGRLNYVMSNSFAFGGSNACLIFCRKGA
CCCCCCEEEECCHHHHHCCCEEEEEECCEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10784042; 11481430 [H]