BacMap

Definition	Shewanella sp. ANA-3 chromosome chromosome 1, complete sequence.
Accession	NC_008577
Length	4,972,204

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The map label for this gene is fabG [H]

Identifier: 117918784

GI number: 117918784

Start: 361715

End: 362440

Strand: Reverse

Name: fabG [H]

Synonym: Shewana3_0327

Alternate gene names: 117918784

Gene position: 362440-361715 (Counterclockwise)

Preceding gene: 117918785

Following gene: 117918783

Centisome position: 7.29

GC content: 53.99

Gene sequence:

>726_bases
ATGAATAACAGAGTATTAGTCACAGGTTCGAGCCGCGGTATTGGCAAAGCCATCGCCCTTAAACTGGCCGCGGCGGGCTA
CGATATCGCGCTGCATTATCACAGCAATCAGGCCGCAGCCGATGCCAGCGCCGCAGAGCTTAGCGCCCTTGGGGTGAACG
TCAGCCTATTGAAGTTTGATGTTGCCGACCGCGCCGCGGTAAAAGCCGCCATTGAGGCCGATATCGAGGCCAATGGCGCC
TATTATGGCGTGATACTCAATGCTGGCATCAACCGTGACAATGCCTTCCCAGCGATGAGTGAAGCCGAGTGGGACAGCGT
GATCCACACTAACCTCGATGGTTTTTACAATGTCATTCACCCCTGCGTAATGCCCATGGTACAAGGCCGCAAGGGTGGCC
GTATCATCACTCTAGCCTCAGTGTCAGGCATTGCGGGCAACCGTGGACAGGTCAACTACAGCGCCTCTAAGGCCGGGTTG
ATTGGTGCCACTAAGGCGCTGTCCTTAGAGCTGGCCAAACGTAAAATCACCGTCAACTGTATCGCCCCAGGTTTGATCGA
AACCGATATGGTGGCGGATATTCCTAAGGATATGGTCGAGCAGTTAGTGCCTATGCGACGCATGGGTAAACCGAATGAAA
TCGCCGCCTTAGCCGCTTTTTTAATGTCGGACGATGCTGCCTATATCACGCGCCAAGTGATTTCGGTGAATGGAGGCATG
ATCTAA

Upstream 100 bases:

>100_bases
CAAGCTTTAAACCGACGCAACGTCAGTCGCACTACAAAAGGATTTAGCCCTTTGATGCATAAACAACTCATCATCAAGCA
TCACGGGTGGAGAAATAAAG

Downstream 100 bases:

>100_bases
ATGACGCAGCGCAATCCCCTAGGCAGACGAGTCGTCGTTACTGGTATCGGTGGCATCAGTGCCCTAGGCCATGACTGGCC
GAGTATCGCAAGCAGCCTTA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MNNRVLVTGSSRGIGKAIALKLAAAGYDIALHYHSNQAAADASAAELSALGVNVSLLKFDVADRAAVKAAIEADIEANGA
YYGVILNAGINRDNAFPAMSEAEWDSVIHTNLDGFYNVIHPCVMPMVQGRKGGRIITLASVSGIAGNRGQVNYSASKAGL
IGATKALSLELAKRKITVNCIAPGLIETDMVADIPKDMVEQLVPMRRMGKPNEIAALAAFLMSDDAAYITRQVISVNGGM
I

Sequences:

>Translated_241_residues
MNNRVLVTGSSRGIGKAIALKLAAAGYDIALHYHSNQAAADASAAELSALGVNVSLLKFDVADRAAVKAAIEADIEANGA
YYGVILNAGINRDNAFPAMSEAEWDSVIHTNLDGFYNVIHPCVMPMVQGRKGGRIITLASVSGIAGNRGQVNYSASKAGL
IGATKALSLELAKRKITVNCIAPGLIETDMVADIPKDMVEQLVPMRRMGKPNEIAALAAFLMSDDAAYITRQVISVNGGM
I
>Mature_241_residues
MNNRVLVTGSSRGIGKAIALKLAAAGYDIALHYHSNQAAADASAAELSALGVNVSLLKFDVADRAAVKAAIEADIEANGA
YYGVILNAGINRDNAFPAMSEAEWDSVIHTNLDGFYNVIHPCVMPMVQGRKGGRIITLASVSGIAGNRGQVNYSASKAGL
IGATKALSLELAKRKITVNCIAPGLIETDMVADIPKDMVEQLVPMRRMGKPNEIAALAAFLMSDDAAYITRQVISVNGGM
I

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=36.0995850622407, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=33.852140077821, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=31.8367346938775, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=31.3492063492063, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI4504505, Length=228, Percent_Identity=32.8947368421053, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.5220883534137, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI19923817, Length=245, Percent_Identity=27.7551020408163, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=31.7948717948718, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI66933014, Length=150, Percent_Identity=28.6666666666667, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=28.8, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4503301, Length=206, Percent_Identity=28.6407766990291, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI59889578, Length=192, Percent_Identity=31.25, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI31542939, Length=239, Percent_Identity=27.6150627615063, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=43.9834024896266, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=34.6938775510204, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=34.9593495934959, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=34.7107438016529, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=29.7520661157025, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=32.0833333333333, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=28.6307053941909, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=29.4605809128631, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=30.241935483871, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=27.0161290322581, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=28.2442748091603, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786701, Length=197, Percent_Identity=27.9187817258883, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=35.1464435146443, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=36.6666666666667, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=30.7692307692308, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17568967, Length=239, Percent_Identity=32.2175732217573, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=31.1740890688259, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=31.6205533596838, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=28.7937743190661, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=25.4032258064516, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=245, Percent_Identity=27.3469387755102, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=244, Percent_Identity=26.6393442622951, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=27.0161290322581, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=234, Percent_Identity=29.4871794871795, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=28.2722513089005, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=26.4822134387352, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=211, Percent_Identity=35.5450236966825, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324126, Length=186, Percent_Identity=28.494623655914, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=36.6666666666667, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=32.9268292682927, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=31.8367346938775, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=28.2786885245902, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18859837, Length=236, Percent_Identity=32.2033898305085, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=28.5123966942149, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357041, Length=245, Percent_Identity=28.1632653061224, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=28.7937743190661, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25285; Mature: 25285

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRVLVTGSSRGIGKAIALKLAAAGYDIALHYHSNQAAADASAAELSALGVNVSLLKFD
CCCEEEEEECCCCCCHHHEEEEEECCEEEEEEECCCCCCCCCCHHHHHHHCCEEEEEEEE
VADRAAVKAAIEADIEANGAYYGVILNAGINRDNAFPAMSEAEWDSVIHTNLDGFYNVIH
CHHHHHHHHHHHCCEECCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHH
PCVMPMVQGRKGGRIITLASVSGIAGNRGQVNYSASKAGLIGATKALSLELAKRKITVNC
HHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCEEHHHHHHHEEHHEEEEEEE
IAPGLIETDMVADIPKDMVEQLVPMRRMGKPNEIAALAAFLMSDDAAYITRQVISVNGGM
ECCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
I
C
>Mature Secondary Structure
MNNRVLVTGSSRGIGKAIALKLAAAGYDIALHYHSNQAAADASAAELSALGVNVSLLKFD
CCCEEEEEECCCCCCHHHEEEEEECCEEEEEEECCCCCCCCCCHHHHHHHCCEEEEEEEE
VADRAAVKAAIEADIEANGAYYGVILNAGINRDNAFPAMSEAEWDSVIHTNLDGFYNVIH
CHHHHHHHHHHHCCEECCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHH
PCVMPMVQGRKGGRIITLASVSGIAGNRGQVNYSASKAGLIGATKALSLELAKRKITVNC
HHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCCEEHHHHHHHEEHHEEEEEEE
IAPGLIETDMVADIPKDMVEQLVPMRRMGKPNEIAALAAFLMSDDAAYITRQVISVNGGM
ECCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]