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The map label for this gene is yqhD [H]

Identifier: 117918718

GI number: 117918718

Start: 292460

End: 293617

Strand: Reverse

Name: yqhD [H]

Synonym: Shewana3_0261

Alternate gene names: 117918718

Gene position: 293617-292460 (Counterclockwise)

Preceding gene: 117918719

Following gene: 117918717

Centisome position: 5.91

GC content: 50.35

Gene sequence:

>1158_bases
ATGTTCAATTTCGCCTACTACAACCCAACCCGAATCCACTTTGGTAAAAACACCATAGCTGAAATCGATACCTTAGTACC
TCGCAATGCCAGAGTCATGGTGTTATTTGGCGGCAGCAGCGCCAGACGAACAGGCACCTTAGCCGAAGTAAAACAAGCGC
TTGGAAACCGTTTTGTGGTCGAGTTTGAAGGAATCGAGCCTAACCCAACCTACGAAACCCTGATGCAGGCTGTCGAGCAA
GTTCGTGAATTAAACATCGACTTTTTACTCGCAGTCGGCGGCGGTTCTGTGATCGATGGTACCAAGTTTGTTGCTGCGGC
AGCGGTATTTGAAGGCGAGCCTTGGGATATCCTCACCAGCTGGGGCGCGAATGTGACTCAAGCCATGCCATTTGGCTCGG
TATTAACCTTGCCTGCGACGGGTTCAGAGATGAACAACGCCAGCGTGGTGACCCGTAAATCGTTAAAAGCTAAACTGCCA
TTCCGTAACGACTTGGTTTATCCGCAATTCTCAATCCTCGACCCTACTAAGACCTTCACCCTACCAGAAAGACAAGTGGC
GAACGGCGTGGTCGATGCCTTTGTGCATATCACGGAGCAGTACCTCACCTATCCGGTCAATGCAGCTGTGCAGGACAGAT
TCGCCGAAGGCTTACTGCAAATTTTGATTGAACTTGGGCCTCAGGCACTCACACAGCCCGAAGATTACGATATTCGCGCC
AACTTGATGTGGGTCGCGACTATGGCACTCAATGGCACGATTGCGACAGGTGTACCCCACGACTGGGCAACACATATGAT
CGGCCATGAACTCACAGCCTTGTATGATATTGACCATGCCCGCACCTTAGCCATTGTATTACCAGCATTATTGCGCTGCA
CTAAAGCCGCTAAGCGTGAAAAGCTGCTGCAGTTTGCAGACAGAGTGTGGCATATCAACACTGGCTCTGAAGACGAACGT
ATTGAGGCCGCCATTGCGAAAACCCAAGCCTTCTTCGAGTCCATGGGCATTGCAACTCATTTATCTGCCTACGATTTAGG
AAAAGAAGCTGTCGATGCTGTCGTCAATCAGCTTGAACAGCATGGCATGGTTGCCCTAGGCGAGCATGGCAATATCGATC
CCACTATGAGCCGCGATATTTTAACCCTAGCGCTCTAA

Upstream 100 bases:

>100_bases
TGAAATATCGCCTCATCGGCCTGATTTATCATTTAGTAGCCAACCAATCTAGACGACTGGTCTACTAAAATTATTTTCCA
ACCATAGGACACATAGCAGT

Downstream 100 bases:

>100_bases
GCTTTGGTTGCCGCCGTCAACGCACCATAGTGGTGCGTTGACTCTCCCCTAAAAGAGGCAAACTCCCCTGCGCCTCAACA
TCAAAGCCGCTCTCACCTTT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MFNFAYYNPTRIHFGKNTIAEIDTLVPRNARVMVLFGGSSARRTGTLAEVKQALGNRFVVEFEGIEPNPTYETLMQAVEQ
VRELNIDFLLAVGGGSVIDGTKFVAAAAVFEGEPWDILTSWGANVTQAMPFGSVLTLPATGSEMNNASVVTRKSLKAKLP
FRNDLVYPQFSILDPTKTFTLPERQVANGVVDAFVHITEQYLTYPVNAAVQDRFAEGLLQILIELGPQALTQPEDYDIRA
NLMWVATMALNGTIATGVPHDWATHMIGHELTALYDIDHARTLAIVLPALLRCTKAAKREKLLQFADRVWHINTGSEDER
IEAAIAKTQAFFESMGIATHLSAYDLGKEAVDAVVNQLEQHGMVALGEHGNIDPTMSRDILTLAL

Sequences:

>Translated_385_residues
MFNFAYYNPTRIHFGKNTIAEIDTLVPRNARVMVLFGGSSARRTGTLAEVKQALGNRFVVEFEGIEPNPTYETLMQAVEQ
VRELNIDFLLAVGGGSVIDGTKFVAAAAVFEGEPWDILTSWGANVTQAMPFGSVLTLPATGSEMNNASVVTRKSLKAKLP
FRNDLVYPQFSILDPTKTFTLPERQVANGVVDAFVHITEQYLTYPVNAAVQDRFAEGLLQILIELGPQALTQPEDYDIRA
NLMWVATMALNGTIATGVPHDWATHMIGHELTALYDIDHARTLAIVLPALLRCTKAAKREKLLQFADRVWHINTGSEDER
IEAAIAKTQAFFESMGIATHLSAYDLGKEAVDAVVNQLEQHGMVALGEHGNIDPTMSRDILTLAL
>Mature_385_residues
MFNFAYYNPTRIHFGKNTIAEIDTLVPRNARVMVLFGGSSARRTGTLAEVKQALGNRFVVEFEGIEPNPTYETLMQAVEQ
VRELNIDFLLAVGGGSVIDGTKFVAAAAVFEGEPWDILTSWGANVTQAMPFGSVLTLPATGSEMNNASVVTRKSLKAKLP
FRNDLVYPQFSILDPTKTFTLPERQVANGVVDAFVHITEQYLTYPVNAAVQDRFAEGLLQILIELGPQALTQPEDYDIRA
NLMWVATMALNGTIATGVPHDWATHMIGHELTALYDIDHARTLAIVLPALLRCTKAAKREKLLQFADRVWHINTGSEDER
IEAAIAKTQAFFESMGIATHLSAYDLGKEAVDAVVNQLEQHGMVALGEHGNIDPTMSRDILTLAL

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=285, Percent_Identity=23.859649122807, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789386, Length=386, Percent_Identity=57.2538860103627, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI48994951, Length=313, Percent_Identity=24.2811501597444, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082107, Length=276, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1789163, Length=329, Percent_Identity=25.2279635258359, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537053, Length=280, Percent_Identity=24.2857142857143, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321181, Length=370, Percent_Identity=24.5945945945946, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42300; Mature: 42300

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNFAYYNPTRIHFGKNTIAEIDTLVPRNARVMVLFGGSSARRTGTLAEVKQALGNRFVV
CCEEEEECCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCEEEE
EFEGIEPNPTYETLMQAVEQVRELNIDFLLAVGGGSVIDGTKFVAAAAVFEGEPWDILTS
EEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEECCHHHHHHHHHCCCCCCHHHHH
WGANVTQAMPFGSVLTLPATGSEMNNASVVTRKSLKAKLPFRNDLVYPQFSILDPTKTFT
CCCCHHHCCCCCCEEEECCCCCCCCCCCEEEHHHHHEECCCCCCCCCCCEEECCCCCCCC
LPERQVANGVVDAFVHITEQYLTYPVNAAVQDRFAEGLLQILIELGPQALTQPEDYDIRA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCEEE
NLMWVATMALNGTIATGVPHDWATHMIGHELTALYDIDHARTLAIVLPALLRCTKAAKRE
EEEEEEEEHCCCEEECCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHH
KLLQFADRVWHINTGSEDERIEAAIAKTQAFFESMGIATHLSAYDLGKEAVDAVVNQLEQ
HHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHH
HGMVALGEHGNIDPTMSRDILTLAL
CCCEEECCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MFNFAYYNPTRIHFGKNTIAEIDTLVPRNARVMVLFGGSSARRTGTLAEVKQALGNRFVV
CCEEEEECCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCEEEE
EFEGIEPNPTYETLMQAVEQVRELNIDFLLAVGGGSVIDGTKFVAAAAVFEGEPWDILTS
EEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEECCHHHHHHHHHCCCCCCHHHHH
WGANVTQAMPFGSVLTLPATGSEMNNASVVTRKSLKAKLPFRNDLVYPQFSILDPTKTFT
CCCCHHHCCCCCCEEEECCCCCCCCCCCEEEHHHHHEECCCCCCCCCCCEEECCCCCCCC
LPERQVANGVVDAFVHITEQYLTYPVNAAVQDRFAEGLLQILIELGPQALTQPEDYDIRA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCEEE
NLMWVATMALNGTIATGVPHDWATHMIGHELTALYDIDHARTLAIVLPALLRCTKAAKRE
EEEEEEEEHCCCEEECCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHH
KLLQFADRVWHINTGSEDERIEAAIAKTQAFFESMGIATHLSAYDLGKEAVDAVVNQLEQ
HHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHH
HGMVALGEHGNIDPTMSRDILTLAL
CCCEEECCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]