Click here to switch to the map view.

The map label for this gene is merP [H]

Identifier: 117676280

GI number: 117676280

Start: 229627

End: 229902

Strand: Direct

Name: merP [H]

Synonym: Shewana3_4343

Alternate gene names: 117676280

Gene position: 229627-229902 (Clockwise)

Preceding gene: 117676279

Following gene: 117676281

Centisome position: 82.32

GC content: 61.96

Gene sequence:

>276_bases
ATGAAAAAACTGTTTGCCGCCCTCGCCCTCGCTGCCGTTGTTGCCCCCGTGTGGGCCGCCACCCAGACCGTCACGCTGTC
CGTGCCTGGCATGACCTGCGCCTCTTGCCCGATCACTGTCAAGCACGCGCTTTCCAAGGTTGAGGGCGTGAGCAAGACCG
ACGTAAGTTTCGACAAGCGCCAGGCCGTCGTCACCTTCGACGATGCCAAGACCAACGTCCAGAAGTTGACCAAGGCGACC
GAGGACGCGGGCTATCCGTCCAGCCTCAAACGCTGA

Upstream 100 bases:

>100_bases
TACTTACAAGCTCATTTTCTGGATCGTGGCCGCGCTGGTCCTGGTCTCGCTCGGATTTCCCTACGTCATGCCATTTTTCT
ATTAATCACAGGAGTTCATC

Downstream 100 bases:

>100_bases
TCCGTTAACCGAACTCGGGAGCGACACATGGGACTCATCACGCGCATCGCTGGCAAAACCGGCGCGCTCGGCAGCGTCGT
TTCCGCGATGGGCTGCGCCG

Product: mercuric transport protein periplasmic component

Products: ADP; Orthophosphate. [C]

Alternate protein names: Mercury scavenger protein; Periplasmic mercury ion-binding protein [H]

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCASCPITVKHALSKVEGVSKTDVSFDKRQAVVTFDDAKTNVQKLTKAT
EDAGYPSSLKR

Sequences:

>Translated_91_residues
MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCASCPITVKHALSKVEGVSKTDVSFDKRQAVVTFDDAKTNVQKLTKAT
EDAGYPSSLKR
>Mature_91_residues
MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCASCPITVKHALSKVEGVSKTDVSFDKRQAVVTFDDAKTNVQKLTKAT
EDAGYPSSLKR

Specific function: Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (merA) via the merT protein [H]

COG id: COG2608

COG function: function code P; Copper chaperone

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR001802
- InterPro:   IPR011795 [H]

Pfam domain/function: PF00403 HMA [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 9611; Mature: 9611

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCASCPITVKHALSKVEGVSKTDVSFDKR
CHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
QAVVTFDDAKTNVQKLTKATEDAGYPSSLKR
EEEEEECCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCASCPITVKHALSKVEGVSKTDVSFDKR
CHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
QAVVTFDDAKTNVQKLTKATEDAGYPSSLKR
EEEEEECCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8302940 [H]