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The map label for this gene is thyX [H]

Identifier: 117621645

GI number: 117621645

Start: 59105

End: 59908

Strand: Direct

Name: thyX [H]

Synonym: BAPKO_2074

Alternate gene names: 117621645

Gene position: 59105-59908 (Clockwise)

Preceding gene: 117621644

Following gene: NA

Centisome position: 98.58

GC content: 29.73

Gene sequence:

>804_bases
TTGAATAAAGAATATAAAATTCTGGATAATGGCTTTATAAAGCTTATTGATTTTATGGGGAATGATAAGAGAATAGTTGA
GGCCGCAAGGATTTCTTATCGAGGAGACAGTGTAAAAAGGAAAGATGAGGAACTTATTGACTATTTAATAAGAAATGGAC
ATACAAGTCCATTGGAGCAGGTGGTTTTTACATTTCATGTTAAAGCTCCAATATTTATTGCAAGGCAGTGGATGAGGCAC
AGAACTGCAAGGATTAATGAAGTTTCTGGATGTTATAGCTTAGCAAGAGAAGAATTTTATGTCCCTTTAGAAGAGGATTT
GAAGTATCAAATTTCTAGTAATAGTCAACCCAAAAGAGAATTTGATTCTTTGGAAAAAAAATTATCAGACAAAATAAAAT
ATCATCAAAAACATTCTTATAAGCTTTATCAAGATATGGTCAATTCCAATATTCCAAAAGAACTTTCAAGAATAGTTTTA
CCCTTAAGTTTATATACTGAATGGTATTGGCAAATTGATTTAAATAATCTTTTTCATTTTATTAAATTGCGATTGGCTTT
AGATAATCCAAAAGAAATTAAAGAGAATTCGCCAAAAGAAATGCGTGAATATGCTAAAGCATTGATAAGTATAATAAAAG
AAATTGTTCCCATCTCTTTTAACAGTTTTGAAAATCATTTTTTAAGGGGAAAGAGATTTTCTCGTGAAGAGATAATAGCA
ATTGTTAATGCTTTAGACTTAAACAAGCTTAGTATGGATGCTGAAAAATTAGACTTACTGAAAGATAAGTTGGGAATTGA
TTGA

Upstream 100 bases:

>100_bases
CTCCCCATTAAGGCTATTCTTATGATATAATGTTTGCATCCTTGGTTTTGCATTATGAAAAAAAGTTGACAAATTTGTCT
TTAAGTAGGAGTATTAATTT

Downstream 100 bases:

>50_bases
TTTTTTGGGGTATTATCTTTTTATTTAATAAATAAAAGATTGAAAATTTA

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNKEYKILDNGFIKLIDFMGNDKRIVEAARISYRGDSVKRKDEELIDYLIRNGHTSPLEQVVFTFHVKAPIFIARQWMRH
RTARINEVSGCYSLAREEFYVPLEEDLKYQISSNSQPKREFDSLEKKLSDKIKYHQKHSYKLYQDMVNSNIPKELSRIVL
PLSLYTEWYWQIDLNNLFHFIKLRLALDNPKEIKENSPKEMREYAKALISIIKEIVPISFNSFENHFLRGKRFSREEIIA
IVNALDLNKLSMDAEKLDLLKDKLGID

Sequences:

>Translated_267_residues
MNKEYKILDNGFIKLIDFMGNDKRIVEAARISYRGDSVKRKDEELIDYLIRNGHTSPLEQVVFTFHVKAPIFIARQWMRH
RTARINEVSGCYSLAREEFYVPLEEDLKYQISSNSQPKREFDSLEKKLSDKIKYHQKHSYKLYQDMVNSNIPKELSRIVL
PLSLYTEWYWQIDLNNLFHFIKLRLALDNPKEIKENSPKEMREYAKALISIIKEIVPISFNSFENHFLRGKRFSREEIIA
IVNALDLNKLSMDAEKLDLLKDKLGID
>Mature_267_residues
MNKEYKILDNGFIKLIDFMGNDKRIVEAARISYRGDSVKRKDEELIDYLIRNGHTSPLEQVVFTFHVKAPIFIARQWMRH
RTARINEVSGCYSLAREEFYVPLEEDLKYQISSNSQPKREFDSLEKKLSDKIKYHQKHSYKLYQDMVNSNIPKELSRIVL
PLSLYTEWYWQIDLNNLFHFIKLRLALDNPKEIKENSPKEMREYAKALISIIKEIVPISFNSFENHFLRGKRFSREEIIA
IVNALDLNKLSMDAEKLDLLKDKLGID

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 31650; Mature: 31650

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEYKILDNGFIKLIDFMGNDKRIVEAARISYRGDSVKRKDEELIDYLIRNGHTSPLEQ
CCCCEEEHHCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHH
VVFTFHVKAPIFIARQWMRHRTARINEVSGCYSLAREEFYVPLEEDLKYQISSNSQPKRE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCCCHHH
FDSLEKKLSDKIKYHQKHSYKLYQDMVNSNIPKELSRIVLPLSLYTEWYWQIDLNNLFHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEHHHHHHH
IKLRLALDNPKEIKENSPKEMREYAKALISIIKEIVPISFNSFENHFLRGKRFSREEIIA
HHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHH
IVNALDLNKLSMDAEKLDLLKDKLGID
HHHHHCCHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKEYKILDNGFIKLIDFMGNDKRIVEAARISYRGDSVKRKDEELIDYLIRNGHTSPLEQ
CCCCEEEHHCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHH
VVFTFHVKAPIFIARQWMRHRTARINEVSGCYSLAREEFYVPLEEDLKYQISSNSQPKRE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCCCHHH
FDSLEKKLSDKIKYHQKHSYKLYQDMVNSNIPKELSRIVLPLSLYTEWYWQIDLNNLFHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEHHHHHHH
IKLRLALDNPKEIKENSPKEMREYAKALISIIKEIVPISFNSFENHFLRGKRFSREEIIA
HHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHH
IVNALDLNKLSMDAEKLDLLKDKLGID
HHHHHCCHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]