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The map label for this gene is adhR [H]

Identifier: 116874097

GI number: 116874097

Start: 2711950

End: 2712384

Strand: Direct

Name: adhR [H]

Synonym: lwe2681

Alternate gene names: 116874097

Gene position: 2711950-2712384 (Clockwise)

Preceding gene: 116874096

Following gene: 116874098

Centisome position: 96.37

GC content: 37.7

Gene sequence:

>435_bases
ATGTCAAAAAATGAAACAGTTCTTTTTGCAGTAGATGCCTCTGAGGAATTAACGATGAATATAAAAGAAGCTAGTGAAAA
AAGTGGCGTTTCTGCTGATACAATTCGTTACTATGAACGAATTGGTTTAATTCCTCCTGTACATCGCAATGAAAATGGCG
TGCGCAAATTTGGTGCTGAAGATTTACGTTGGATTCAATTTAGCCGTCAAATGCGTCGTGCTGGTTTATCTATTGAAGCT
CTGATTGATTATTTAGCGCTTTTCCGAGAAGGCGAACATACGCTAGAAGCTCGCGTTGAACTTCTGAAAGAACAGCGCGT
CGACTTAAAAAATCGTATTAATATCATGCAAGAAGCACTCGACCGCCTTGATTTCAAAATTAACAATTATGATACCCATC
TCATTCCCGCACAACAAAAACTAAAAGATTTTTAA

Upstream 100 bases:

>100_bases
AGCCATGAATAAAATTTCCATCATGGTTGTTATTTTTGCTTGACTTAAAGTGAACTCCAAGGAATACAATAACTATATTA
ATAAGCAAAGGAGAATGGTT

Downstream 100 bases:

>100_bases
TCTTGAAAGGAGTAATGCCGCATGACTACACTTGAAAATAGCGTTATTTTTGATAAAGGGGAGCTGATTACAAATGACTA
CTTTATCGGAAATGCTTACT

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSKNETVLFAVDASEELTMNIKEASEKSGVSADTIRYYERIGLIPPVHRNENGVRKFGAEDLRWIQFSRQMRRAGLSIEA
LIDYLALFREGEHTLEARVELLKEQRVDLKNRINIMQEALDRLDFKINNYDTHLIPAQQKLKDF

Sequences:

>Translated_144_residues
MSKNETVLFAVDASEELTMNIKEASEKSGVSADTIRYYERIGLIPPVHRNENGVRKFGAEDLRWIQFSRQMRRAGLSIEA
LIDYLALFREGEHTLEARVELLKEQRVDLKNRINIMQEALDRLDFKINNYDTHLIPAQQKLKDF
>Mature_143_residues
SKNETVLFAVDASEELTMNIKEASEKSGVSADTIRYYERIGLIPPVHRNENGVRKFGAEDLRWIQFSRQMRRAGLSIEAL
IDYLALFREGEHTLEARVELLKEQRVDLKNRINIMQEALDRLDFKINNYDTHLIPAQQKLKDF

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16794; Mature: 16663

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNETVLFAVDASEELTMNIKEASEKSGVSADTIRYYERIGLIPPVHRNENGVRKFGAE
CCCCCEEEEEECCCCHHEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCHH
DLRWIQFSRQMRRAGLSIEALIDYLALFREGEHTLEARVELLKEQRVDLKNRINIMQEAL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DRLDFKINNYDTHLIPAQQKLKDF
HHHCCEECCCCCEEECCHHHHCCC
>Mature Secondary Structure 
SKNETVLFAVDASEELTMNIKEASEKSGVSADTIRYYERIGLIPPVHRNENGVRKFGAE
CCCCEEEEEECCCCHHEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCHH
DLRWIQFSRQMRRAGLSIEALIDYLALFREGEHTLEARVELLKEQRVDLKNRINIMQEAL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
DRLDFKINNYDTHLIPAQQKLKDF
HHHCCEECCCCCEEECCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]