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The map label for this gene is lytG [H]

Identifier: 116873957

GI number: 116873957

Start: 2585785

End: 2587311

Strand: Direct

Name: lytG [H]

Synonym: lwe2541

Alternate gene names: 116873957

Gene position: 2585785-2587311 (Clockwise)

Preceding gene: 116873953

Following gene: 116873968

Centisome position: 91.89

GC content: 35.95

Gene sequence:

>1527_bases
TTGGAGAGAAAGTTTATAAAAACAGGGATTATCATGCTTATTGTAGCATTTTTAGTGGTTTCATTAAATGTTGGAGCAGA
AACGGGAAATTCTAGGACTGCTCAAGTGGCGTTAAGCTCTTCGCAACAATCGTTTATTGACGAAATTTTACCAGCTGCCC
AAGACGGATATCAAAATGGCAAACTCTTGACTAGCGTAACGCTTGCTCAAGCAATTTTGGAATCTAATTGGGGCGAAAGT
GGTTTAAGTAAGAATTCTAATAACTTATTTGGAATTAAAGGTACATATGAAGGTAAGTCTGTTTCAATGGACACGATGGA
AGCCTCTGGAGCGACAACTGCTAATTTCCGAGTTTATCCAAGTTGGAAAGAATCGATTGAAGATCATACAGATTTAATTA
CACAAAACGACCGTTATAAAGGCGCCGTTGGTGAAACTGATTACCGAAAATCTTTACAAGCTATAAAAGATGGTGGTTAT
GCTACTGATCCGGAGTATGTTTCAAAATTAGTAGCTATTATTGAACGTTATAATTTAGATCAATACGATATTGTTTATGA
CAAAATTGAGTCCCATCACAAAGTTGCCGCTATAGGAACCGTATCACCGAATAAAACACAAGAAACCATTTGGTCTGCGC
CTTTTAACACTGCAAATTCGGAGGAAGTCGGGAAACTAGCTAGTTACTCGAATCGTAATTTAGAAGTTTCTTGGGAAGCT
AAGACAGAAAAAGGTTTATGGTATTTCTTACGTGAAAATAATAAAGATATTGGTTGGGTAAATAGTAATGCCCTTAATCT
AAGTTATCATCAGAAAAACGACGAAAACATAAATGCAACTAAATATGTAGATGATATGGGTGCGCATATTTACCGTTTAC
CTAGTCCTGAAAAGCAATTTGATAATGGTACAATTGCACAATATGACAAGAAAACACTTCATGCTGATAAAAAAATCACT
CGTGATGGATACGCTTGGTTCCGTCTTTCTGAAAGTAATGAAGTAATCGGTTGGGTTCGCGCAGATAAATTGAATGATCG
TTTATATGACCGTATTACTGAACAAACCACGTATAATGGCTATGCGACAGTAAATAAAGCAGCGACTGATAATGTTTGGA
GTGCCCCTTTTAACACTAAGAATTCGAATAAAATAGCACCTCTTACTGATTATAATGCAGCGAAACTAGAGCTTGTATCG
CGCGCTAAAGTTGCTAACACCATATGGTACGAGTTTAAACTAGATGGCAAACTAATTGGTTGGACTAGTGAAAAGGATTT
AAACATTATCTATACTCCTGAAAACGAAAAACCAACAACTCAAGTCGCTTACGTAAAAAATCCAACAGCAATGCTTTATA
ATAAACCCGTAGAAACAACAAGCACTCAAACAAAAGAAATCGGTTTTTATTATGGTAAGTTACTAGCTGTTGATAAAGAA
GCTACTATTCAAGCTGAAAAATGGGTTCATATTAAAGATAGTAATAACTCACTTGGCTGGATTAAAGCAGAAGACATTCA
ACGTTAA

Upstream 100 bases:

>100_bases
TCGCCTTTTGTCTTGTTTTCGTCATAGAATTGTAACAGACTATTTCTTTTGTTTGTTGCTAATATAGTGGCAGATATAGT
AAAAAGGAGTGCGTTCGATT

Downstream 100 bases:

>100_bases
TTTTAAAAAGAGGGCCCAGATAATTTCTGACCCTCTTTTTTTATATATTTTCAATTAGATATTCATTTTGCGGCTAGCCA
TCCATTTAATCATTTCTGGA

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Autolysin lytG; Exo-beta-N-acetylglucosaminidase lytG; Peptidoglycan hydrolase lytG [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MERKFIKTGIIMLIVAFLVVSLNVGAETGNSRTAQVALSSSQQSFIDEILPAAQDGYQNGKLLTSVTLAQAILESNWGES
GLSKNSNNLFGIKGTYEGKSVSMDTMEASGATTANFRVYPSWKESIEDHTDLITQNDRYKGAVGETDYRKSLQAIKDGGY
ATDPEYVSKLVAIIERYNLDQYDIVYDKIESHHKVAAIGTVSPNKTQETIWSAPFNTANSEEVGKLASYSNRNLEVSWEA
KTEKGLWYFLRENNKDIGWVNSNALNLSYHQKNDENINATKYVDDMGAHIYRLPSPEKQFDNGTIAQYDKKTLHADKKIT
RDGYAWFRLSESNEVIGWVRADKLNDRLYDRITEQTTYNGYATVNKAATDNVWSAPFNTKNSNKIAPLTDYNAAKLELVS
RAKVANTIWYEFKLDGKLIGWTSEKDLNIIYTPENEKPTTQVAYVKNPTAMLYNKPVETTSTQTKEIGFYYGKLLAVDKE
ATIQAEKWVHIKDSNNSLGWIKAEDIQR

Sequences:

>Translated_508_residues
MERKFIKTGIIMLIVAFLVVSLNVGAETGNSRTAQVALSSSQQSFIDEILPAAQDGYQNGKLLTSVTLAQAILESNWGES
GLSKNSNNLFGIKGTYEGKSVSMDTMEASGATTANFRVYPSWKESIEDHTDLITQNDRYKGAVGETDYRKSLQAIKDGGY
ATDPEYVSKLVAIIERYNLDQYDIVYDKIESHHKVAAIGTVSPNKTQETIWSAPFNTANSEEVGKLASYSNRNLEVSWEA
KTEKGLWYFLRENNKDIGWVNSNALNLSYHQKNDENINATKYVDDMGAHIYRLPSPEKQFDNGTIAQYDKKTLHADKKIT
RDGYAWFRLSESNEVIGWVRADKLNDRLYDRITEQTTYNGYATVNKAATDNVWSAPFNTKNSNKIAPLTDYNAAKLELVS
RAKVANTIWYEFKLDGKLIGWTSEKDLNIIYTPENEKPTTQVAYVKNPTAMLYNKPVETTSTQTKEIGFYYGKLLAVDKE
ATIQAEKWVHIKDSNNSLGWIKAEDIQR
>Mature_508_residues
MERKFIKTGIIMLIVAFLVVSLNVGAETGNSRTAQVALSSSQQSFIDEILPAAQDGYQNGKLLTSVTLAQAILESNWGES
GLSKNSNNLFGIKGTYEGKSVSMDTMEASGATTANFRVYPSWKESIEDHTDLITQNDRYKGAVGETDYRKSLQAIKDGGY
ATDPEYVSKLVAIIERYNLDQYDIVYDKIESHHKVAAIGTVSPNKTQETIWSAPFNTANSEEVGKLASYSNRNLEVSWEA
KTEKGLWYFLRENNKDIGWVNSNALNLSYHQKNDENINATKYVDDMGAHIYRLPSPEKQFDNGTIAQYDKKTLHADKKIT
RDGYAWFRLSESNEVIGWVRADKLNDRLYDRITEQTTYNGYATVNKAATDNVWSAPFNTKNSNKIAPLTDYNAAKLELVS
RAKVANTIWYEFKLDGKLIGWTSEKDLNIIYTPENEKPTTQVAYVKNPTAMLYNKPVETTSTQTKEIGFYYGKLLAVDKE
ATIQAEKWVHIKDSNNSLGWIKAEDIQR

Specific function: Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility, chemotaxis and cell division [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 73 family [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=150, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000423
- InterPro:   IPR013338
- InterPro:   IPR002901 [H]

Pfam domain/function: PF01832 Glucosaminidase [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 57246; Mature: 57246

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKFIKTGIIMLIVAFLVVSLNVGAETGNSRTAQVALSSSQQSFIDEILPAAQDGYQNG
CCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCC
KLLTSVTLAQAILESNWGESGLSKNSNNLFGIKGTYEGKSVSMDTMEASGATTANFRVYP
EEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEEECC
SWKESIEDHTDLITQNDRYKGAVGETDYRKSLQAIKDGGYATDPEYVSKLVAIIERYNLD
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
QYDIVYDKIESHHKVAAIGTVSPNKTQETIWSAPFNTANSEEVGKLASYSNRNLEVSWEA
HHHHHHHHHHCCCEEEEEEECCCCCCHHHEECCCCCCCCHHHHHHHHHCCCCCEEEEEEC
KTEKGLWYFLRENNKDIGWVNSNALNLSYHQKNDENINATKYVDDMGAHIYRLPSPEKQF
CCCCCEEEEEEECCCCEEEECCCEEEEEEECCCCCCCCHHHHHHHCCCEEEECCCCHHHC
DNGTIAQYDKKTLHADKKITRDGYAWFRLSESNEVIGWVRADKLNDRLYDRITEQTTYNG
CCCCEECCCHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCCC
YATVNKAATDNVWSAPFNTKNSNKIAPLTDYNAAKLELVSRAKVANTIWYEFKLDGKLIG
EEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHCEEEEEEEEECCEEEE
WTSEKDLNIIYTPENEKPTTQVAYVKNPTAMLYNKPVETTSTQTKEIGFYYGKLLAVDKE
ECCCCCCEEEECCCCCCCCEEEEEEECCEEEEECCCCCCCCCCHHHHHEEEEEEEEECCC
ATIQAEKWVHIKDSNNSLGWIKAEDIQR
CEEEEEEEEEEECCCCCEEEEEHHCCCC
>Mature Secondary Structure
MERKFIKTGIIMLIVAFLVVSLNVGAETGNSRTAQVALSSSQQSFIDEILPAAQDGYQNG
CCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCC
KLLTSVTLAQAILESNWGESGLSKNSNNLFGIKGTYEGKSVSMDTMEASGATTANFRVYP
EEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEEECC
SWKESIEDHTDLITQNDRYKGAVGETDYRKSLQAIKDGGYATDPEYVSKLVAIIERYNLD
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
QYDIVYDKIESHHKVAAIGTVSPNKTQETIWSAPFNTANSEEVGKLASYSNRNLEVSWEA
HHHHHHHHHHCCCEEEEEEECCCCCCHHHEECCCCCCCCHHHHHHHHHCCCCCEEEEEEC
KTEKGLWYFLRENNKDIGWVNSNALNLSYHQKNDENINATKYVDDMGAHIYRLPSPEKQF
CCCCCEEEEEEECCCCEEEECCCEEEEEEECCCCCCCCHHHHHHHCCCEEEECCCCHHHC
DNGTIAQYDKKTLHADKKITRDGYAWFRLSESNEVIGWVRADKLNDRLYDRITEQTTYNG
CCCCEECCCHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCCC
YATVNKAATDNVWSAPFNTKNSNKIAPLTDYNAAKLELVSRAKVANTIWYEFKLDGKLIG
EEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHCEEEEEEEEECCEEEE
WTSEKDLNIIYTPENEKPTTQVAYVKNPTAMLYNKPVETTSTQTKEIGFYYGKLLAVDKE
ECCCCCCEEEECCCCCCCCEEEEEEECCEEEEECCCCCCCCCCHHHHHEEEEEEEEECCC
ATIQAEKWVHIKDSNNSLGWIKAEDIQR
CEEEEEEEEEEECCCCCEEEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]