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The map label for this gene is arsC [H]

Identifier: 116873663

GI number: 116873663

Start: 2286197

End: 2286622

Strand: Direct

Name: arsC [H]

Synonym: lwe2247

Alternate gene names: 116873663

Gene position: 2286197-2286622 (Clockwise)

Preceding gene: 116873652

Following gene: 116873664

Centisome position: 81.24

GC content: 35.45

Gene sequence:

>426_bases
ATGACGCAAAAGCTAATTTATTTTTTATCACAAACGCATATTCGAAGTGCCATTGCTGAAGCTTGGGCGAAGAAACTTTC
ACTTAGCAATGTCAAATTCATTAGCGGATCTTGGCATAAATCAAAAGCAACTCCATTTATTGCTGAAGCGTTAAATGAAT
TTGCAATTGAACCACCTGAAAGCTTATCTTATTCTCCTAGCTCAAAACTACTGGCAGAGGCTGATCTCATTGTTACAATT
TATGATTCAGCACACGAAGCAGCACCACGTTTCCCAGCTAATATACAAGATAAAATTATTTATTGGGACATTGATGATCC
AGAACAAGAAATAGCGTTACCAAAAAAATGGGCTTGTTATCAAGAAGTCTGTGATAATATTGCCTTATCCGTAAAAAAAT
TAGAGCATGTATTGATAGAAGCTTAA

Upstream 100 bases:

>100_bases
TGTAACATTTGGTAATAAGAATCAGTTATATACTATGTACAACAAGTAATGGCAACACGTTTTACATGGGTTTATTAATA
AGCCAGAAAGGATTTGGAAT

Downstream 100 bases:

>100_bases
TTTTGTTGTCCCGCCACTCGTAGGCGGGACTTTTATGTTAAGGAAAGGAGTTTACATACTTATGGACGGATATACAGATT
TAAAAAAAGCAGAAAAAGCT

Product: arsenate reductase, putative

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MTQKLIYFLSQTHIRSAIAEAWAKKLSLSNVKFISGSWHKSKATPFIAEALNEFAIEPPESLSYSPSSKLLAEADLIVTI
YDSAHEAAPRFPANIQDKIIYWDIDDPEQEIALPKKWACYQEVCDNIALSVKKLEHVLIEA

Sequences:

>Translated_141_residues
MTQKLIYFLSQTHIRSAIAEAWAKKLSLSNVKFISGSWHKSKATPFIAEALNEFAIEPPESLSYSPSSKLLAEADLIVTI
YDSAHEAAPRFPANIQDKIIYWDIDDPEQEIALPKKWACYQEVCDNIALSVKKLEHVLIEA
>Mature_140_residues
TQKLIYFLSQTHIRSAIAEAWAKKLSLSNVKFISGSWHKSKATPFIAEALNEFAIEPPESLSYSPSSKLLAEADLIVTIY
DSAHEAAPRFPANIQDKIIYWDIDDPEQEIALPKKWACYQEVCDNIALSVKKLEHVLIEA

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15904; Mature: 15773

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKLIYFLSQTHIRSAIAEAWAKKLSLSNVKFISGSWHKSKATPFIAEALNEFAIEPPE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCC
SLSYSPSSKLLAEADLIVTIYDSAHEAAPRFPANIQDKIIYWDIDDPEQEIALPKKWACY
CCCCCCCCHHHCCCCEEEEEECCCHHCCCCCCCCCCCCEEEEECCCCHHHHCCCCCHHHH
QEVCDNIALSVKKLEHVLIEA
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQKLIYFLSQTHIRSAIAEAWAKKLSLSNVKFISGSWHKSKATPFIAEALNEFAIEPPE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCC
SLSYSPSSKLLAEADLIVTIYDSAHEAAPRFPANIQDKIIYWDIDDPEQEIALPKKWACY
CCCCCCCCHHHCCCCEEEEEECCCHHCCCCCCCCCCCCEEEEECCCCHHHHCCCCCHHHH
QEVCDNIALSVKKLEHVLIEA
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]