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The map label for this gene is aroK [H]

Identifier: 116873182

GI number: 116873182

Start: 1793422

End: 1793910

Strand: Direct

Name: aroK [H]

Synonym: lwe1766

Alternate gene names: 116873182

Gene position: 1793422-1793910 (Clockwise)

Preceding gene: 116873168

Following gene: 116873194

Centisome position: 63.73

GC content: 36.4

Gene sequence:

>489_bases
ATGGGAGCTGGAAAAACAACGGTTGGAAATATACTCGCAAAAATGGCTAATTTACCATATATTGATATTGACGAAGTAAT
TATTAGCGAGCAAGGAATGAGTGTATCCGATATTTTTGCCAAACATGGTGAAAAAGAATTCCGACGTCTAGAACATGAAA
AATTAAAAGAGTTAATGGGCACCAAAGCCGTTATAGCGACAGGCGGTGGCATTGTTCTAAATCCTGAAAATAGAAAAGTT
TTGAATGATACATATCCCGTAATTTATTTAGAGACTGATCCAAAAGTATTTATGAACCGGTTAAAAGGTGATACTACTCG
CCCTCTTGTTCAACAAAAAACACCTGAAGAAATTCAAGCGATTTTCGAACCTAGAATCGCCCATTATGAAGCTTCTGCTG
ACTTTATTGTCAACACAGATAACCGTAATCAACAAGAAGTAGCGAAAGCAATTATAGACATGCTTGATAACGAACAAAAA
CAGCGCTAA

Upstream 100 bases:

>100_bases
TGGCATTTGTGATATAATTTCTTTAATGCTTTTAAGTAGTAAAATGTGATAATTAACAAAGGAGGAGAACATCATCGATC
AAGTTATTTTAATTGGCTTC

Downstream 100 bases:

>100_bases
ATTAATAGCGCTGTTTTTCTATTCCGTACAATGTCTGCACCACATATCAGGCAGTACAGATGTATAATCCTTCGTAAAGG
TAAGTAAATCATAAAACATA

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MGAGKTTVGNILAKMANLPYIDIDEVIISEQGMSVSDIFAKHGEKEFRRLEHEKLKELMGTKAVIATGGGIVLNPENRKV
LNDTYPVIYLETDPKVFMNRLKGDTTRPLVQQKTPEEIQAIFEPRIAHYEASADFIVNTDNRNQQEVAKAIIDMLDNEQK
QR

Sequences:

>Translated_162_residues
MGAGKTTVGNILAKMANLPYIDIDEVIISEQGMSVSDIFAKHGEKEFRRLEHEKLKELMGTKAVIATGGGIVLNPENRKV
LNDTYPVIYLETDPKVFMNRLKGDTTRPLVQQKTPEEIQAIFEPRIAHYEASADFIVNTDNRNQQEVAKAIIDMLDNEQK
QR
>Mature_161_residues
GAGKTTVGNILAKMANLPYIDIDEVIISEQGMSVSDIFAKHGEKEFRRLEHEKLKELMGTKAVIATGGGIVLNPENRKVL
NDTYPVIYLETDPKVFMNRLKGDTTRPLVQQKTPEEIQAIFEPRIAHYEASADFIVNTDNRNQQEVAKAIIDMLDNEQKQ
R

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=160, Percent_Identity=37.5, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786587, Length=152, Percent_Identity=34.2105263157895, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 18270; Mature: 18139

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAGKTTVGNILAKMANLPYIDIDEVIISEQGMSVSDIFAKHGEKEFRRLEHEKLKELMG
CCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHC
TKAVIATGGGIVLNPENRKVLNDTYPVIYLETDPKVFMNRLKGDTTRPLVQQKTPEEIQA
CCEEEEECCEEEECCCCCEEECCCCCEEEEECCHHHHHHHHCCCCCCCHHHCCCHHHHHH
IFEPRIAHYEASADFIVNTDNRNQQEVAKAIIDMLDNEQKQR
HHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
GAGKTTVGNILAKMANLPYIDIDEVIISEQGMSVSDIFAKHGEKEFRRLEHEKLKELMG
CCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHC
TKAVIATGGGIVLNPENRKVLNDTYPVIYLETDPKVFMNRLKGDTTRPLVQQKTPEEIQA
CCEEEEECCEEEECCCCCEEECCCCCEEEEECCHHHHHHHHCCCCCCCHHHCCCHHHHHH
IFEPRIAHYEASADFIVNTDNRNQQEVAKAIIDMLDNEQKQR
HHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]