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The map label for this gene is malE [C]

Identifier: 116873163

GI number: 116873163

Start: 1770341

End: 1771582

Strand: Direct

Name: malE [C]

Synonym: lwe1747

Alternate gene names: 116873163

Gene position: 1770341-1771582 (Clockwise)

Preceding gene: 116873149

Following gene: 116873164

Centisome position: 62.91

GC content: 37.6

Gene sequence:

>1242_bases
ATGAAGAAAAAAATGTTTGTAATTTTAGCTTTGGTCTTATCACTTAGTTTGGTCCTAATGGGTTGTGGGTCAAAGGACGA
TGCAAAATCAGGCGATTCCAAAGTGCTAAATGTTTGGGCAATGGGAGATGAAGCCAAGTCATTAAAAGAACTCGCACAAA
AATTCACGAAAGAAACTGGTATTGAAGTAAAAGTCCAAGTTATCCCTTGGGCAAATGCACATGATAAATTACTTACTGCT
GTTGCTTCTAAATCTGGTCCTGATGTAGTACAAATGGGAACTACTTGGATGCCAGAATTTGTTGAAGCTGGGGCATTACT
TGATATTACAAAAGATGTCGAAAAAAGTAAAAATATGAACTCAGATTTATTTTTCCCCGGTTCAGTGAAAACTACACAAT
TTGACGGAAAAACTTACGGTGTTCCTTGGTATGCAGAAACTCGTGTATTATTTTATCGTACTGACTTACTGAAAAAAGTT
GGTTATAATGAAGCACCAAAAACATGGGATGAGCTATCTGATGCTGCACTTAAACTTTCTAAACGTGGAAAAGATATGTA
TGGTTTTGCAATTGATCCAAATGAACAAACAACTGGTTTCATTTTCGGACGCCAAAACGGCTCCCCTCTTTTTGATAAAG
ATGGCAAACCAGTTTTCAATAAAAAACCATTCGTAGATACTGTCACTTATTTAGACAGTTTCATCAAAAACGGTTCCGCA
CCAGACACTGACCTTGGATTAGATGCTTCACAAAGCTTTGGTGGCGACGGAATTGTGCCGATGTTCATGAGTGGTCCTTG
GATGGTTAATACACTCAAAGACACTGCTCCTGACATTGACGGCAAATGGGCTACTGCTGTATTACCTAAAAAAGAAAATA
ATGAATCCAGCCTAGGTGGCGCTAACCTTTCCATTTTCAAATATAGTGATAAAAAAGATGATGCACTAAAATTCATGGAT
TATATGAGTCAACCTGATGTGCAATTATCGTGGTTAAAAGATACTAACTCCATGCCAGCTCGTATGGATGCTTGGGAAGA
TGACATGCTAAAAAACGACCCTTACTACAAAGTATTCGGTGAACAAATGAAGACTGCTGAACCAATGCCACTTATCCCAC
AATTTGAAGAAATTGCGCAATTATATGGCAAATCTTGGGAGCAAATTTATCGTGGTGGTGTAGATGTACAAACACAAATG
GATTCCTTTAACGATCAAGTAGAAACACTTCTTAAAAAATAA

Upstream 100 bases:

>100_bases
CCCGTACGGTACGCTTTTATTCCGTACAATAGTTTTTATTCTTTAACAGCTTCAGTCAGGAAAAGTTGCTTTGAAAAAAA
CAAAAAATGGAGGAAAAATC

Downstream 100 bases:

>100_bases
CGAATAAAAAGGGCAAATGATCCACTTTGCCATTTGCCCTTTTAGAATGGAACTGATGTTATGAAACAATTTTTAAATAA
AAACACCCCCTATTTGTTTA

Product: ABC transporter, substrate-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKKKMFVILALVLSLSLVLMGCGSKDDAKSGDSKVLNVWAMGDEAKSLKELAQKFTKETGIEVKVQVIPWANAHDKLLTA
VASKSGPDVVQMGTTWMPEFVEAGALLDITKDVEKSKNMNSDLFFPGSVKTTQFDGKTYGVPWYAETRVLFYRTDLLKKV
GYNEAPKTWDELSDAALKLSKRGKDMYGFAIDPNEQTTGFIFGRQNGSPLFDKDGKPVFNKKPFVDTVTYLDSFIKNGSA
PDTDLGLDASQSFGGDGIVPMFMSGPWMVNTLKDTAPDIDGKWATAVLPKKENNESSLGGANLSIFKYSDKKDDALKFMD
YMSQPDVQLSWLKDTNSMPARMDAWEDDMLKNDPYYKVFGEQMKTAEPMPLIPQFEEIAQLYGKSWEQIYRGGVDVQTQM
DSFNDQVETLLKK

Sequences:

>Translated_413_residues
MKKKMFVILALVLSLSLVLMGCGSKDDAKSGDSKVLNVWAMGDEAKSLKELAQKFTKETGIEVKVQVIPWANAHDKLLTA
VASKSGPDVVQMGTTWMPEFVEAGALLDITKDVEKSKNMNSDLFFPGSVKTTQFDGKTYGVPWYAETRVLFYRTDLLKKV
GYNEAPKTWDELSDAALKLSKRGKDMYGFAIDPNEQTTGFIFGRQNGSPLFDKDGKPVFNKKPFVDTVTYLDSFIKNGSA
PDTDLGLDASQSFGGDGIVPMFMSGPWMVNTLKDTAPDIDGKWATAVLPKKENNESSLGGANLSIFKYSDKKDDALKFMD
YMSQPDVQLSWLKDTNSMPARMDAWEDDMLKNDPYYKVFGEQMKTAEPMPLIPQFEEIAQLYGKSWEQIYRGGVDVQTQM
DSFNDQVETLLKK
>Mature_413_residues
MKKKMFVILALVLSLSLVLMGCGSKDDAKSGDSKVLNVWAMGDEAKSLKELAQKFTKETGIEVKVQVIPWANAHDKLLTA
VASKSGPDVVQMGTTWMPEFVEAGALLDITKDVEKSKNMNSDLFFPGSVKTTQFDGKTYGVPWYAETRVLFYRTDLLKKV
GYNEAPKTWDELSDAALKLSKRGKDMYGFAIDPNEQTTGFIFGRQNGSPLFDKDGKPVFNKKPFVDTVTYLDSFIKNGSA
PDTDLGLDASQSFGGDGIVPMFMSGPWMVNTLKDTAPDIDGKWATAVLPKKENNESSLGGANLSIFKYSDKKDDALKFMD
YMSQPDVQLSWLKDTNSMPARMDAWEDDMLKNDPYYKVFGEQMKTAEPMPLIPQFEEIAQLYGKSWEQIYRGGVDVQTQM
DSFNDQVETLLKK

Specific function: Probably part of an ABC transporter complex [H]

COG id: COG1653

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790466, Length=378, Percent_Identity=26.4550264550265, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787569, Length=396, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059
- InterPro:   IPR006061 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 46098; Mature: 46098

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKMFVILALVLSLSLVLMGCGSKDDAKSGDSKVLNVWAMGDEAKSLKELAQKFTKETG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCC
IEVKVQVIPWANAHDKLLTAVASKSGPDVVQMGTTWMPEFVEAGALLDITKDVEKSKNMN
CEEEEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHCCCEEEHHHHHHHHCCCC
SDLFFPGSVKTTQFDGKTYGVPWYAETRVLFYRTDLLKKVGYNEAPKTWDELSDAALKLS
CCEEECCCCEEEEECCEEECCCCEECCEEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHH
KRGKDMYGFAIDPNEQTTGFIFGRQNGSPLFDKDGKPVFNKKPFVDTVTYLDSFIKNGSA
HCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
PDTDLGLDASQSFGGDGIVPMFMSGPWMVNTLKDTAPDIDGKWATAVLPKKENNESSLGG
CCCCCCCCCCCCCCCCCCEEHEECCCEEEEEHHHCCCCCCCCEEEEECCCCCCCCCCCCC
ANLSIFKYSDKKDDALKFMDYMSQPDVQLSWLKDTNSMPARMDAWEDDMLKNDPYYKVFG
CEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCHHHHHH
EQMKTAEPMPLIPQFEEIAQLYGKSWEQIYRGGVDVQTQMDSFNDQVETLLKK
HHHHCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKKMFVILALVLSLSLVLMGCGSKDDAKSGDSKVLNVWAMGDEAKSLKELAQKFTKETG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCC
IEVKVQVIPWANAHDKLLTAVASKSGPDVVQMGTTWMPEFVEAGALLDITKDVEKSKNMN
CEEEEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHCCCEEEHHHHHHHHCCCC
SDLFFPGSVKTTQFDGKTYGVPWYAETRVLFYRTDLLKKVGYNEAPKTWDELSDAALKLS
CCEEECCCCEEEEECCEEECCCCEECCEEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHH
KRGKDMYGFAIDPNEQTTGFIFGRQNGSPLFDKDGKPVFNKKPFVDTVTYLDSFIKNGSA
HCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
PDTDLGLDASQSFGGDGIVPMFMSGPWMVNTLKDTAPDIDGKWATAVLPKKENNESSLGG
CCCCCCCCCCCCCCCCCCEEHEECCCEEEEEHHHCCCCCCCCEEEEECCCCCCCCCCCCC
ANLSIFKYSDKKDDALKFMDYMSQPDVQLSWLKDTNSMPARMDAWEDDMLKNDPYYKVFG
CEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCHHHHHH
EQMKTAEPMPLIPQFEEIAQLYGKSWEQIYRGGVDVQTQMDSFNDQVETLLKK
HHHHCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA