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The map label for this gene is cymR [H]

Identifier: 116872944

GI number: 116872944

Start: 1525440

End: 1525862

Strand: Direct

Name: cymR [H]

Synonym: lwe1528

Alternate gene names: 116872944

Gene position: 1525440-1525862 (Clockwise)

Preceding gene: 116872937

Following gene: 116872945

Centisome position: 54.21

GC content: 40.43

Gene sequence:

>423_bases
ATGAAAATTACAACGAAAGGTCGTTATGGCCTAACAATAACACTTGAACTAGCGAAAAGAATTGGTGATGGTCCTATTTC
TCTTCGTAGTATCGCACAAGATAAAAACCTATCCGAACATTATTTAGAACAATTAATCGGACCACTGCGTAATGCAGGAA
TTGTTAAAAGTATTCGCGGAGCTCATGGAGGTTATATTTTAAACGGCGACCCAGAAAAAATCACTGCTGGTGATATCATT
CGTACATTAGAAGGTCCTATCGTACTTGTTGAAAGCATGGAAGACGAGGAAGCTGCCCAACGAGAACTATGGACGCGAAT
GCGCAATGCTGTCCGTGACGTGTTAGATCAAACAACCCTTGCCGACCTACTAAAACATTCTACGGATTCTGAGTTGTCTG
ATGGTTACATGTTTTATATTTGA

Upstream 100 bases:

>100_bases
CTGTACGTTTAGCCGCTTGTTTCCTTTGCCTTCTATCCGTAATTCCGATATAATAAGTACGATATAAGTGTTTTTTGAAA
TTACTGGAGGTTAAATAAAA

Downstream 100 bases:

>100_bases
TAAAAAAGCCTATTTTAAAAGTAGGCTTTTTATCTGCCATTTAAACGGAATTTACGCCCTTTAATTATCTGATTATTCCG
AAATAAACCCAAAAACCATT

Product: Rrf2 family protein

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MKITTKGRYGLTITLELAKRIGDGPISLRSIAQDKNLSEHYLEQLIGPLRNAGIVKSIRGAHGGYILNGDPEKITAGDII
RTLEGPIVLVESMEDEEAAQRELWTRMRNAVRDVLDQTTLADLLKHSTDSELSDGYMFYI

Sequences:

>Translated_140_residues
MKITTKGRYGLTITLELAKRIGDGPISLRSIAQDKNLSEHYLEQLIGPLRNAGIVKSIRGAHGGYILNGDPEKITAGDII
RTLEGPIVLVESMEDEEAAQRELWTRMRNAVRDVLDQTTLADLLKHSTDSELSDGYMFYI
>Mature_140_residues
MKITTKGRYGLTITLELAKRIGDGPISLRSIAQDKNLSEHYLEQLIGPLRNAGIVKSIRGAHGGYILNGDPEKITAGDII
RTLEGPIVLVESMEDEEAAQRELWTRMRNAVRDVLDQTTLADLLKHSTDSELSDGYMFYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=132, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15584; Mature: 15584

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITTKGRYGLTITLELAKRIGDGPISLRSIAQDKNLSEHYLEQLIGPLRNAGIVKSIRG
CCCCCCCCCCEEEEHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCC
AHGGYILNGDPEKITAGDIIRTLEGPIVLVESMEDEEAAQRELWTRMRNAVRDVLDQTTL
CCCCEEECCCCCCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADLLKHSTDSELSDGYMFYI
HHHHHCCCCCCCCCCEEEEC
>Mature Secondary Structure
MKITTKGRYGLTITLELAKRIGDGPISLRSIAQDKNLSEHYLEQLIGPLRNAGIVKSIRG
CCCCCCCCCCEEEEHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCC
AHGGYILNGDPEKITAGDIIRTLEGPIVLVESMEDEEAAQRELWTRMRNAVRDVLDQTTL
CCCCEEECCCCCCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADLLKHSTDSELSDGYMFYI
HHHHHCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]