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The map label for this gene is ftsK [H]

Identifier: 116872818

GI number: 116872818

Start: 1389151

End: 1391433

Strand: Direct

Name: ftsK [H]

Synonym: lwe1402

Alternate gene names: 116872818

Gene position: 1389151-1391433 (Clockwise)

Preceding gene: 116872817

Following gene: 116872820

Centisome position: 49.36

GC content: 37.41

Gene sequence:

>2283_bases
ATGGCGACACAAAAGAAAAAAACGACTGGACGAAAGAAAACGTCCACACGTTCAAAAAAGAAAAAATCTGCTTCTTTTCG
TATAGAGATAACAGGTATAGTGCTCATTGCAATAGGGCTTATCGGAATATTACAATTAGGTTTTATCGGTCGAGGTTTTT
TTGCTCTGGCTGAAATGTTTGTTGGTCTTCTAAGCTATGTTTTACTTGCAGGAATAGTTATACTTGGTGGTTATATGGTT
ATTAGAAGGAAGATGCCTCGCCTTTTTAGCAAACGATTAGTAGGTATTTATCTGATTGTTTTAGGCTTTTTAACATATAT
ACATATGTATTTTATTATTCATCATTTAGGGGCAAATGCGCCTGTTGTTTCCAGTACATGGAAATTAGTACTAGAAAATT
TATTTAGACCAAATCAAGTGAGTTTTGTTGGCGCGGGGATGATTGGTGCCGCTATTACTTCGGTCACGTATTTCTTGCTG
GACCGCCTTGGGACAAATATTATAGCTATTCTTTTAATTATTTATGGTTTTTCACTTGTATCCGGCGTTTCTATTCGTCA
ATTTTTCTCAAAAATAACAGAGTTTGTTCGTTACTTATTTTCAAAAGGTAAAGCAGCAACAGAAAAAGGTAAAGAAGTAA
AAGCAAAACGAGATAAAAAGAAAGCTGAAAAAGCGGTTGATGTAGAGCCAGACGAAGTAATTGAGGTAGTCCAACCACTA
ACATCTATCAAAGAAGAAAAAACGCCACCAATTATTTCGAATTTTAGTTCCAAAGTAGAACAAGAGAAAGCACCTTTGGA
AGAAAACGTAGATGTGAAAGAAAAAGAACTAGAAATGTTCCAACAAGAATCCTTTGAAAATGAAATTTATCAATTACCAC
CAGTAGATATTTTAGCACCAGCCAAAGTTACGGACCAAAGTAAAGAATATGACCAAATCAAAGTCAATGCAAAAAAATTA
GAAGATACTTTTGAAAGCTTTGGAGTAAAAGCGAAAATTACACAAGTACATCTAGGACCGGCAGTGACAAAATATGAAGT
GCAGCCATCTGTAGGTGTCAAAGTAAGTAAAATTGTTTCATTAAGTGATGATATTGCTCTTGCTTTAGCTGCAAAGGACA
TTCGTATTGAAGCGCCGATTCCAGGTAAATCTGCTATTGGTATTGAAGTAGCCAACCAGAATGTAGCAATGGTTTCTTTA
CGTGAGGTGTTAGAAAATAATCCAAAAAACAATCCGGATGAAAAATTACAAATTGCGCTCGGTCGAGATATTTCTGGCGA
GGCAATGATGGCCAACCTCGACAAAATGCCCCATCTGCTTGTAGCGGGAGCGACTGGTAGTGGGAAATCCGTTTGTATTA
ATGGCATCATTACGAGCATTTTGCTTCGTGCTAAACCACATGAAGTAAAAATGATGATGATAGATCCTAAAATGGTAGAG
TTAAACGTGTATAATGGTATTCCGCATTTACTTGCACCAGTTGTCACTAATCCTAAAAAAGCCGCTCAAGCTTTGCAAAA
AGTAGTTGCTGAAATGGAGCGCCGTTATGATTTGTTTTCACATACAGGTACGCGAAATATGCAAGGCTATAATGATTATG
TAAAAAAACAAAATGAGCTTAACGAAGAAAAACAACCAGAATTACCGTTTATTGTAGTAATTGTGGATGAATTAGCAGAT
TTAATGATGGTTGCTTCAAATGATGTAGAAGATGCTATTACACGACTTGCACAAATGGCTCGTGCAGCTGGAATACATTT
AATTATTGCAACTCAACGACCATCTGTGGATGTAATTACAGGAGTTATTAAAGCAAATATTCCATCTCGAATCGCTTTTG
CTGTATCTAGTTCTATTGATTCAAGGACTATTTTAGATATGGGCGGGGCGGAAAAACTATTAGGTCGGGGAGATATGTTA
CTTCTTCCTGTTGGATCTAGCAAGCCAACTCGCATCCAAGGTGCCTTTTTATCCGATGCTGAAGTGGAGGATGTTGTTAA
TTATGTTATCTCACAACAAAAGGCGCAGTATGTGGAAGAAATGATACCTGATGATATTCCTGAGGTGGAAGGCGAAGTTA
CCGATGAACTTTATCATGAAGCTGTGGAGCTTGTTGTAGAAATGCAAACAGCCTCTGTATCCATGTTGCAAAGAAAATTC
CGGATTGGCTATAACCGGGCAGCAAGATTAATTGATGAAATGGAGCAAAGAGGCGTCGTCGGACCTCATGAAGGTAGCAA
ACCAAGACGTGTAAATGTGGAAATCACACCGGATAATGAATAA

Upstream 100 bases:

>100_bases
AGGAAACATTTGTTTGTATAATAGGGCTATAGTATGAGCTACAGAATGAATAGATGTGCTATAATGAAACAAGCAAAAAA
AGGAATAGGTGGGACTTGAA

Downstream 100 bases:

>100_bases
ATGAAAAAGGTTGCGACTTTATGCGCAACCTTTTTTTAAGATAATAAATCTCGTTTTTGGGCTTCGATTTCTTTTTTGCT
TGAGGCGTATTTTCCTTGAG

Product: FtsK/SpoIIIE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MATQKKKTTGRKKTSTRSKKKKSASFRIEITGIVLIAIGLIGILQLGFIGRGFFALAEMFVGLLSYVLLAGIVILGGYMV
IRRKMPRLFSKRLVGIYLIVLGFLTYIHMYFIIHHLGANAPVVSSTWKLVLENLFRPNQVSFVGAGMIGAAITSVTYFLL
DRLGTNIIAILLIIYGFSLVSGVSIRQFFSKITEFVRYLFSKGKAATEKGKEVKAKRDKKKAEKAVDVEPDEVIEVVQPL
TSIKEEKTPPIISNFSSKVEQEKAPLEENVDVKEKELEMFQQESFENEIYQLPPVDILAPAKVTDQSKEYDQIKVNAKKL
EDTFESFGVKAKITQVHLGPAVTKYEVQPSVGVKVSKIVSLSDDIALALAAKDIRIEAPIPGKSAIGIEVANQNVAMVSL
REVLENNPKNNPDEKLQIALGRDISGEAMMANLDKMPHLLVAGATGSGKSVCINGIITSILLRAKPHEVKMMMIDPKMVE
LNVYNGIPHLLAPVVTNPKKAAQALQKVVAEMERRYDLFSHTGTRNMQGYNDYVKKQNELNEEKQPELPFIVVIVDELAD
LMMVASNDVEDAITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSSIDSRTILDMGGAEKLLGRGDML
LLPVGSSKPTRIQGAFLSDAEVEDVVNYVISQQKAQYVEEMIPDDIPEVEGEVTDELYHEAVELVVEMQTASVSMLQRKF
RIGYNRAARLIDEMEQRGVVGPHEGSKPRRVNVEITPDNE

Sequences:

>Translated_760_residues
MATQKKKTTGRKKTSTRSKKKKSASFRIEITGIVLIAIGLIGILQLGFIGRGFFALAEMFVGLLSYVLLAGIVILGGYMV
IRRKMPRLFSKRLVGIYLIVLGFLTYIHMYFIIHHLGANAPVVSSTWKLVLENLFRPNQVSFVGAGMIGAAITSVTYFLL
DRLGTNIIAILLIIYGFSLVSGVSIRQFFSKITEFVRYLFSKGKAATEKGKEVKAKRDKKKAEKAVDVEPDEVIEVVQPL
TSIKEEKTPPIISNFSSKVEQEKAPLEENVDVKEKELEMFQQESFENEIYQLPPVDILAPAKVTDQSKEYDQIKVNAKKL
EDTFESFGVKAKITQVHLGPAVTKYEVQPSVGVKVSKIVSLSDDIALALAAKDIRIEAPIPGKSAIGIEVANQNVAMVSL
REVLENNPKNNPDEKLQIALGRDISGEAMMANLDKMPHLLVAGATGSGKSVCINGIITSILLRAKPHEVKMMMIDPKMVE
LNVYNGIPHLLAPVVTNPKKAAQALQKVVAEMERRYDLFSHTGTRNMQGYNDYVKKQNELNEEKQPELPFIVVIVDELAD
LMMVASNDVEDAITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSSIDSRTILDMGGAEKLLGRGDML
LLPVGSSKPTRIQGAFLSDAEVEDVVNYVISQQKAQYVEEMIPDDIPEVEGEVTDELYHEAVELVVEMQTASVSMLQRKF
RIGYNRAARLIDEMEQRGVVGPHEGSKPRRVNVEITPDNE
>Mature_759_residues
ATQKKKTTGRKKTSTRSKKKKSASFRIEITGIVLIAIGLIGILQLGFIGRGFFALAEMFVGLLSYVLLAGIVILGGYMVI
RRKMPRLFSKRLVGIYLIVLGFLTYIHMYFIIHHLGANAPVVSSTWKLVLENLFRPNQVSFVGAGMIGAAITSVTYFLLD
RLGTNIIAILLIIYGFSLVSGVSIRQFFSKITEFVRYLFSKGKAATEKGKEVKAKRDKKKAEKAVDVEPDEVIEVVQPLT
SIKEEKTPPIISNFSSKVEQEKAPLEENVDVKEKELEMFQQESFENEIYQLPPVDILAPAKVTDQSKEYDQIKVNAKKLE
DTFESFGVKAKITQVHLGPAVTKYEVQPSVGVKVSKIVSLSDDIALALAAKDIRIEAPIPGKSAIGIEVANQNVAMVSLR
EVLENNPKNNPDEKLQIALGRDISGEAMMANLDKMPHLLVAGATGSGKSVCINGIITSILLRAKPHEVKMMMIDPKMVEL
NVYNGIPHLLAPVVTNPKKAAQALQKVVAEMERRYDLFSHTGTRNMQGYNDYVKKQNELNEEKQPELPFIVVIVDELADL
MMVASNDVEDAITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSSIDSRTILDMGGAEKLLGRGDMLL
LPVGSSKPTRIQGAFLSDAEVEDVVNYVISQQKAQYVEEMIPDDIPEVEGEVTDELYHEAVELVVEMQTASVSMLQRKFR
IGYNRAARLIDEMEQRGVVGPHEGSKPRRVNVEITPDNE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=484, Percent_Identity=47.9338842975207, Blast_Score=414, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 83956; Mature: 83825

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQKKKTTGRKKTSTRSKKKKSASFRIEITGIVLIAIGLIGILQLGFIGRGFFALAEMF
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VGLLSYVLLAGIVILGGYMVIRRKMPRLFSKRLVGIYLIVLGFLTYIHMYFIIHHLGANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVVSSTWKLVLENLFRPNQVSFVGAGMIGAAITSVTYFLLDRLGTNIIAILLIIYGFSLV
CCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
SGVSIRQFFSKITEFVRYLFSKGKAATEKGKEVKAKRDKKKAEKAVDVEPDEVIEVVQPL
CCHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TSIKEEKTPPIISNFSSKVEQEKAPLEENVDVKEKELEMFQQESFENEIYQLPPVDILAP
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCEECC
AKVTDQSKEYDQIKVNAKKLEDTFESFGVKAKITQVHLGPAVTKYEVQPSVGVKVSKIVS
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHC
LSDDIALALAAKDIRIEAPIPGKSAIGIEVANQNVAMVSLREVLENNPKNNPDEKLQIAL
CCCCCEEEEEEECEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHEEEEE
GRDISGEAMMANLDKMPHLLVAGATGSGKSVCINGIITSILLRAKPHEVKMMMIDPKMVE
CCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCEEEE
LNVYNGIPHLLAPVVTNPKKAAQALQKVVAEMERRYDLFSHTGTRNMQGYNDYVKKQNEL
EEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
NEEKQPELPFIVVIVDELADLMMVASNDVEDAITRLAQMARAAGIHLIIATQRPSVDVIT
CCCCCCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHH
GVIKANIPSRIAFAVSSSIDSRTILDMGGAEKLLGRGDMLLLPVGSSKPTRIQGAFLSDA
HHHHCCCCHHHHHHHHCCCCCCEEECCCCHHHHHCCCCEEEEECCCCCCCEEEECCCCCC
EVEDVVNYVISQQKAQYVEEMIPDDIPEVEGEVTDELYHEAVELVVEMQTASVSMLQRKF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIGYNRAARLIDEMEQRGVVGPHEGSKPRRVNVEITPDNE
HHCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
ATQKKKTTGRKKTSTRSKKKKSASFRIEITGIVLIAIGLIGILQLGFIGRGFFALAEMF
CCCCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VGLLSYVLLAGIVILGGYMVIRRKMPRLFSKRLVGIYLIVLGFLTYIHMYFIIHHLGANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVVSSTWKLVLENLFRPNQVSFVGAGMIGAAITSVTYFLLDRLGTNIIAILLIIYGFSLV
CCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
SGVSIRQFFSKITEFVRYLFSKGKAATEKGKEVKAKRDKKKAEKAVDVEPDEVIEVVQPL
CCHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TSIKEEKTPPIISNFSSKVEQEKAPLEENVDVKEKELEMFQQESFENEIYQLPPVDILAP
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCEECC
AKVTDQSKEYDQIKVNAKKLEDTFESFGVKAKITQVHLGPAVTKYEVQPSVGVKVSKIVS
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHC
LSDDIALALAAKDIRIEAPIPGKSAIGIEVANQNVAMVSLREVLENNPKNNPDEKLQIAL
CCCCCEEEEEEECEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHEEEEE
GRDISGEAMMANLDKMPHLLVAGATGSGKSVCINGIITSILLRAKPHEVKMMMIDPKMVE
CCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCEEEE
LNVYNGIPHLLAPVVTNPKKAAQALQKVVAEMERRYDLFSHTGTRNMQGYNDYVKKQNEL
EEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
NEEKQPELPFIVVIVDELADLMMVASNDVEDAITRLAQMARAAGIHLIIATQRPSVDVIT
CCCCCCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHH
GVIKANIPSRIAFAVSSSIDSRTILDMGGAEKLLGRGDMLLLPVGSSKPTRIQGAFLSDA
HHHHCCCCHHHHHHHHCCCCCCEEECCCCHHHHHCCCCEEEEECCCCCCCEEEECCCCCC
EVEDVVNYVISQQKAQYVEEMIPDDIPEVEGEVTDELYHEAVELVVEMQTASVSMLQRKF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIGYNRAARLIDEMEQRGVVGPHEGSKPRRVNVEITPDNE
HHCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]