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The map label for this gene is racE [H]

Identifier: 116872608

GI number: 116872608

Start: 1204678

End: 1205478

Strand: Direct

Name: racE [H]

Synonym: lwe1192

Alternate gene names: 116872608

Gene position: 1204678-1205478 (Clockwise)

Preceding gene: 116872606

Following gene: 116872609

Centisome position: 42.81

GC content: 37.95

Gene sequence:

>801_bases
GTGAAACAAGCTATTGGCTTTATTGATTCGGGAGTAGGCGGTTTGACAGTAGTGCGAGAAGTGCTAAAACAGCTACCCCA
TGAACAAGTATATTATTTAGGAGATACCGCACGTTGCCCTTATGGACCACGTGACAAAGAAGAAGTAGCTAAGTTTACTT
GGGAAATGACTAATTTCTTAGTAGATCGCGGAATCAAAATGCTCGTTATTGCTTGTAATACCGCAACCGCAGCTGCACTA
TATGATATTCGTGAAAAATTGGATATTCCTGTGATTGGCGTTATTCAACCAGGTTCAAGAGCAGCACTAAAAGCAACTAA
AAATAACAAAATCGGCGTTTTAGGAACGATTGGAACCGTCGAAAGCATGGCATATCCAACGGCATTAAAAGGATTAAATC
GCCGGGTAGAAGTAGATTCGCTTGCTTGTCCAAAATTTGTATCTGTCGTAGAATCTGGTGAGTACAAAAGTGCTATTGCT
AAAAAAGTAGTAGCTGAATCACTTTTACCACTTAAAAGCACCAAGATTGATACGGTAATTTTAGGTTGCACACATTACCC
ACTTTTAAAACCGATTATTGAGAATTTTATGGGCGATGGTGTGTCAGTCATTAACTCTGGGGAAGAAACGGCAAGTGAAG
TAAGTGCCTTACTAGATTATCATAATTTACTAGATGCCACAGATGAAGAAATTGAACATCGTTTTTTCACAACAGGTTCC
ACACAAATTTTCAAAGATATTGCAAAAGACTGGTTAAATATGCCAGATATGATAGTAGAACATATAAAACTAGGAAAATA
A

Upstream 100 bases:

>100_bases
AGCTTTTTTCATAGAAAAGACTTGCGAAAAAGCCGAAAAATAAGAAAATGGAAGGTATAGATAAAAAAATGGAAATTAAT
AAAGAAATTGAGGCGAGACT

Downstream 100 bases:

>100_bases
GAGGTGTCACTAATGAGAGTTGATGGAAGAGAAAAAAATGCACTACGAAAAATCGAAGTCACACCAGATTACTTAATGCA
TCCAGAAGGTTCTGTGTTAA

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKQAIGFIDSGVGGLTVVREVLKQLPHEQVYYLGDTARCPYGPRDKEEVAKFTWEMTNFLVDRGIKMLVIACNTATAAAL
YDIREKLDIPVIGVIQPGSRAALKATKNNKIGVLGTIGTVESMAYPTALKGLNRRVEVDSLACPKFVSVVESGEYKSAIA
KKVVAESLLPLKSTKIDTVILGCTHYPLLKPIIENFMGDGVSVINSGEETASEVSALLDYHNLLDATDEEIEHRFFTTGS
TQIFKDIAKDWLNMPDMIVEHIKLGK

Sequences:

>Translated_266_residues
MKQAIGFIDSGVGGLTVVREVLKQLPHEQVYYLGDTARCPYGPRDKEEVAKFTWEMTNFLVDRGIKMLVIACNTATAAAL
YDIREKLDIPVIGVIQPGSRAALKATKNNKIGVLGTIGTVESMAYPTALKGLNRRVEVDSLACPKFVSVVESGEYKSAIA
KKVVAESLLPLKSTKIDTVILGCTHYPLLKPIIENFMGDGVSVINSGEETASEVSALLDYHNLLDATDEEIEHRFFTTGS
TQIFKDIAKDWLNMPDMIVEHIKLGK
>Mature_266_residues
MKQAIGFIDSGVGGLTVVREVLKQLPHEQVYYLGDTARCPYGPRDKEEVAKFTWEMTNFLVDRGIKMLVIACNTATAAAL
YDIREKLDIPVIGVIQPGSRAALKATKNNKIGVLGTIGTVESMAYPTALKGLNRRVEVDSLACPKFVSVVESGEYKSAIA
KKVVAESLLPLKSTKIDTVILGCTHYPLLKPIIENFMGDGVSVINSGEETASEVSALLDYHNLLDATDEEIEHRFFTTGS
TQIFKDIAKDWLNMPDMIVEHIKLGK

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis [H]

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family [H]

Homologues:

Organism=Escherichia coli, GI87082355, Length=244, Percent_Identity=31.1475409836066, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391 [H]

Pfam domain/function: PF01177 Asp_Glu_race [H]

EC number: =5.1.1.3 [H]

Molecular weight: Translated: 29160; Mature: 29160

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00923 ASP_GLU_RACEMASE_1 ; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQAIGFIDSGVGGLTVVREVLKQLPHEQVYYLGDTARCPYGPRDKEEVAKFTWEMTNFL
CCCHHHHHHCCCCHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
VDRGIKMLVIACNTATAAALYDIREKLDIPVIGVIQPGSRAALKATKNNKIGVLGTIGTV
HHCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCEEEEECCHHH
ESMAYPTALKGLNRRVEVDSLACPKFVSVVESGEYKSAIAKKVVAESLLPLKSTKIDTVI
HHHHHHHHHHHCCCEECCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEE
LGCTHYPLLKPIIENFMGDGVSVINSGEETASEVSALLDYHNLLDATDEEIEHRFFTTGS
ECCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
TQIFKDIAKDWLNMPDMIVEHIKLGK
HHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKQAIGFIDSGVGGLTVVREVLKQLPHEQVYYLGDTARCPYGPRDKEEVAKFTWEMTNFL
CCCHHHHHHCCCCHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
VDRGIKMLVIACNTATAAALYDIREKLDIPVIGVIQPGSRAALKATKNNKIGVLGTIGTV
HHCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCEEEEECCHHH
ESMAYPTALKGLNRRVEVDSLACPKFVSVVESGEYKSAIAKKVVAESLLPLKSTKIDTVI
HHHHHHHHHHHCCCEECCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEE
LGCTHYPLLKPIIENFMGDGVSVINSGEETASEVSALLDYHNLLDATDEEIEHRFFTTGS
ECCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
TQIFKDIAKDWLNMPDMIVEHIKLGK
HHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]