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The map label for this gene is cbiL [H]

Identifier: 116872576

GI number: 116872576

Start: 1168915

End: 1169625

Strand: Direct

Name: cbiL [H]

Synonym: lwe1160

Alternate gene names: 116872576

Gene position: 1168915-1169625 (Clockwise)

Preceding gene: 116872575

Following gene: 116872577

Centisome position: 41.54

GC content: 38.26

Gene sequence:

>711_bases
GTGGCTAAGTTTTATGGCATTGGTACAGGACCAGGCGACAGCAAATTAGTTACGATGGAAGCAGCAGAGCGACTCGGAAA
ACTAGCAATTCTTTATACGCCACAACCTAAAAAAGGTGGCGAAAGTTTAGCTAAGAAAATCGTCAGCCCTTATTTAAAAG
ACACATTAATCATCAAAGAACGCCATTTTCCAATGAATTACAACAAAGAAGAAAAAATGCTTGCATGGAGAGAAATTGCG
GAAGAAATCAAAACAGATGTTCAAAACGGACATGATGTTGGTTTTATCACACTTGGCGACCCAATGGTTTATAGCACCTA
TAGTTATTTACTGGAACTATTGAAAGGTGACATAGAAACAGTGACGCTCGCAGGCATTTCCTCATTTTCAAATATCGCCT
CCAAAATTGAACTACCTCTTGTGATGGACGAGGAAAGTTTTGCTGTTATTCCAGTAACAGCAGGAGCCAGTAGAATCGAA
CAAGCACTCACATTATTTGACACAGTTGTCTTAATGAAAGCAGCAAGCAATTTACCCCTTCTTACGACATTACTAAAAAA
ACTGAATTTGCTTGATGCAGCGGTAGTAGTAAGCGATGTTGCTATGGCGACAGAAAATATCATATACGGCATGCAAAATA
TCAATCCAGCAGAAAAAATGTCCTATTTTACCACAATTATCGTAAAAAAAAGATGGGAGCAATATAAATGA

Upstream 100 bases:

>100_bases
ATTCAAACCGAATGTCACTTGCAAGGTTTAGGTGAAAATCCACTTATCCAAGCCCAGTTTATTGACCATATTCATACTGC
TATAGAAAGGGTGAAAGCGC

Downstream 100 bases:

>100_bases
AAAAAGTATGGAAGTTTTTACCATTTGTTTTAATCGCAGTTATTTATTTTACTTTAACAAATCCAGAATCCGCGCATGCA
ATGCATATTATGGAGGGTTT

Product: cobalt-precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MAKFYGIGTGPGDSKLVTMEAAERLGKLAILYTPQPKKGGESLAKKIVSPYLKDTLIIKERHFPMNYNKEEKMLAWREIA
EEIKTDVQNGHDVGFITLGDPMVYSTYSYLLELLKGDIETVTLAGISSFSNIASKIELPLVMDEESFAVIPVTAGASRIE
QALTLFDTVVLMKAASNLPLLTTLLKKLNLLDAAVVVSDVAMATENIIYGMQNINPAEKMSYFTTIIVKKRWEQYK

Sequences:

>Translated_236_residues
MAKFYGIGTGPGDSKLVTMEAAERLGKLAILYTPQPKKGGESLAKKIVSPYLKDTLIIKERHFPMNYNKEEKMLAWREIA
EEIKTDVQNGHDVGFITLGDPMVYSTYSYLLELLKGDIETVTLAGISSFSNIASKIELPLVMDEESFAVIPVTAGASRIE
QALTLFDTVVLMKAASNLPLLTTLLKKLNLLDAAVVVSDVAMATENIIYGMQNINPAEKMSYFTTIIVKKRWEQYK
>Mature_235_residues
AKFYGIGTGPGDSKLVTMEAAERLGKLAILYTPQPKKGGESLAKKIVSPYLKDTLIIKERHFPMNYNKEEKMLAWREIAE
EIKTDVQNGHDVGFITLGDPMVYSTYSYLLELLKGDIETVTLAGISSFSNIASKIELPLVMDEESFAVIPVTAGASRIEQ
ALTLFDTVVLMKAASNLPLLTTLLKKLNLLDAAVVVSDVAMATENIIYGMQNINPAEKMSYFTTIIVKKRWEQYK

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 26175; Mature: 26044

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFYGIGTGPGDSKLVTMEAAERLGKLAILYTPQPKKGGESLAKKIVSPYLKDTLIIKE
CCEEEECCCCCCCCEEEEHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEE
RHFPMNYNKEEKMLAWREIAEEIKTDVQNGHDVGFITLGDPMVYSTYSYLLELLKGDIET
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCE
VTLAGISSFSNIASKIELPLVMDEESFAVIPVTAGASRIEQALTLFDTVVLMKAASNLPL
EEEHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHH
LTTLLKKLNLLDAAVVVSDVAMATENIIYGMQNINPAEKMSYFTTIIVKKRWEQYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKFYGIGTGPGDSKLVTMEAAERLGKLAILYTPQPKKGGESLAKKIVSPYLKDTLIIKE
CEEEECCCCCCCCEEEEHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEE
RHFPMNYNKEEKMLAWREIAEEIKTDVQNGHDVGFITLGDPMVYSTYSYLLELLKGDIET
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCE
VTLAGISSFSNIASKIELPLVMDEESFAVIPVTAGASRIEQALTLFDTVVLMKAASNLPL
EEEHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHH
LTTLLKKLNLLDAAVVVSDVAMATENIIYGMQNINPAEKMSYFTTIIVKKRWEQYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]