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The map label for this gene is cbiA [H]

Identifier: 116872564

GI number: 116872564

Start: 1158179

End: 1159537

Strand: Direct

Name: cbiA [H]

Synonym: lwe1148

Alternate gene names: 116872564

Gene position: 1158179-1159537 (Clockwise)

Preceding gene: 116872563

Following gene: 116872565

Centisome position: 41.16

GC content: 41.43

Gene sequence:

>1359_bases
ATGAACAAGATCTTAATTGCAGCTGCATCAAGTGGCGCTGGGAAAACAACCATAACGCTCGGAATTATGCGTGCCCTCAA
ACAAAGAGGTTTAGTGGTTCAGCCATTTAAGGTTGGACCAGATTATATTGACACAAATTATCATCAAGCGATAACAGGGG
AAGCATCCATCAATTTAGATAGTTTTCTAATTGATGATGAAGACATGCTCGCGGCACTTTTTCAGAAGCATGGGAAGGTG
GCTGACATTTCGGTCATTGAAGGTGTGATGGGGTTGTTTGATGGACTTGGTACTCATCGTGATAATGCAAGCACGTCCTT
TATTGCCAAATGTACGAAAACACCAGTCATTTTAGTTGTAGATGGAAAAGCAATTTCGACTTCAGCGGCGGCAATTGTTG
ATGGTTTTAATCGTTTTGACCCAGAGCTTGCTATTGCTGGCGTGATTATTAATCGAGTGGCTTCAGAAAATCATTTTTCA
TTGATCAAAGGGGCGATTGAACGTTATACGGATGTCCCTGTGTTAGGTTATTTACCGAAAAATGCGGCAGTGGCACTTCC
AGAAAGACATCTTGGTTTAGTACCTCAAGAAGAAATGGCAGAATTAGATGCAAAATGGGAGTTGCTTGGTGATTTAATCG
GCGAACATGTGGATTTAGATAGATTGTTAGAAATTAGTAAGACTGGTGCAGATTTAGATATAACATCACCTGAGATAAAT
GTGCCAGACTTTTCTGGGATACGCGTTGCTTATGCGCTAGACGCCGCATTTCATTTTTATTATCAAGATAATTTGGAGCT
GATTCGTTCAACTGGTGCTAGGTTGATTCCATTTAGTCCACTAGAAGATAGGGAAGTTCCAGAAGCAGATTTTATCTATA
TTGGTGGCGGTTTTCCAGAAGTTTTTGCGGAGCGCCTTGCGAAGAATAAAACGATGCGAGAATCGATTTTAACTGCGCAT
GAAAAAGGCAAGCCGGTTTATGCCGAATGCGGCGGTTTAATGTATCTTGGTTCGAGCTTGGAAATGGAAGACGAATGTTA
TGAAATGGTGGGCGTTTTTGCAGGGGTTAGTAAGATGACAACACGACTTCGGAAGTTCGGTTATTGTATCGCGGAACCGC
TAGCAGACACACTGATTGGCGAGAAGGGAACTGCTATCCGGGGTCATGAATTTCATCATTCTGTTTTTGAAACAACGGAA
AAACCTTGCATGAAACTTTTGAAAAAGCGAGATGGCGAAATTGTTAAAGAATGGTATGGCGGCTATCAAAAGGGTCATAC
ATTCGCGAGTTACTTGCATATTCATTTCTATCAAAACCCAGCCATTTTAACGCATATGTTTGGAGCTTGTAGAAAATGA

Upstream 100 bases:

>100_bases
TTTGTGCTACAAGGAAATAGCTTGTTTGCGTAAATCTCAAAAAGACGCCAAAGTTCTGTTTGGTGTCTTTTTTTATGGCT
AAAATGAAAGGTGAAAAAAG

Downstream 100 bases:

>100_bases
CATTACTATTCTATACAGCATCATTTATTTTAGATTGTTTGTTAGGGGATCCTTATAGCTGGCCGCATCCAATTAAAGCA
ATTGGCAATTGGATTCAATT

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNKILIAAASSGAGKTTITLGIMRALKQRGLVVQPFKVGPDYIDTNYHQAITGEASINLDSFLIDDEDMLAALFQKHGKV
ADISVIEGVMGLFDGLGTHRDNASTSFIAKCTKTPVILVVDGKAISTSAAAIVDGFNRFDPELAIAGVIINRVASENHFS
LIKGAIERYTDVPVLGYLPKNAAVALPERHLGLVPQEEMAELDAKWELLGDLIGEHVDLDRLLEISKTGADLDITSPEIN
VPDFSGIRVAYALDAAFHFYYQDNLELIRSTGARLIPFSPLEDREVPEADFIYIGGGFPEVFAERLAKNKTMRESILTAH
EKGKPVYAECGGLMYLGSSLEMEDECYEMVGVFAGVSKMTTRLRKFGYCIAEPLADTLIGEKGTAIRGHEFHHSVFETTE
KPCMKLLKKRDGEIVKEWYGGYQKGHTFASYLHIHFYQNPAILTHMFGACRK

Sequences:

>Translated_452_residues
MNKILIAAASSGAGKTTITLGIMRALKQRGLVVQPFKVGPDYIDTNYHQAITGEASINLDSFLIDDEDMLAALFQKHGKV
ADISVIEGVMGLFDGLGTHRDNASTSFIAKCTKTPVILVVDGKAISTSAAAIVDGFNRFDPELAIAGVIINRVASENHFS
LIKGAIERYTDVPVLGYLPKNAAVALPERHLGLVPQEEMAELDAKWELLGDLIGEHVDLDRLLEISKTGADLDITSPEIN
VPDFSGIRVAYALDAAFHFYYQDNLELIRSTGARLIPFSPLEDREVPEADFIYIGGGFPEVFAERLAKNKTMRESILTAH
EKGKPVYAECGGLMYLGSSLEMEDECYEMVGVFAGVSKMTTRLRKFGYCIAEPLADTLIGEKGTAIRGHEFHHSVFETTE
KPCMKLLKKRDGEIVKEWYGGYQKGHTFASYLHIHFYQNPAILTHMFGACRK
>Mature_452_residues
MNKILIAAASSGAGKTTITLGIMRALKQRGLVVQPFKVGPDYIDTNYHQAITGEASINLDSFLIDDEDMLAALFQKHGKV
ADISVIEGVMGLFDGLGTHRDNASTSFIAKCTKTPVILVVDGKAISTSAAAIVDGFNRFDPELAIAGVIINRVASENHFS
LIKGAIERYTDVPVLGYLPKNAAVALPERHLGLVPQEEMAELDAKWELLGDLIGEHVDLDRLLEISKTGADLDITSPEIN
VPDFSGIRVAYALDAAFHFYYQDNLELIRSTGARLIPFSPLEDREVPEADFIYIGGGFPEVFAERLAKNKTMRESILTAH
EKGKPVYAECGGLMYLGSSLEMEDECYEMVGVFAGVSKMTTRLRKFGYCIAEPLADTLIGEKGTAIRGHEFHHSVFETTE
KPCMKLLKKRDGEIVKEWYGGYQKGHTFASYLHIHFYQNPAILTHMFGACRK

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 49742; Mature: 49742

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKILIAAASSGAGKTTITLGIMRALKQRGLVVQPFKVGPDYIDTNYHQAITGEASINLD
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCCCCH
SFLIDDEDMLAALFQKHGKVADISVIEGVMGLFDGLGTHRDNASTSFIAKCTKTPVILVV
HEEECCHHHHHHHHHHCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEE
DGKAISTSAAAIVDGFNRFDPELAIAGVIINRVASENHFSLIKGAIERYTDVPVLGYLPK
CCCCCCCHHHHHHHCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCC
NAAVALPERHLGLVPQEEMAELDAKWELLGDLIGEHVDLDRLLEISKTGADLDITSPEIN
CCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEECCCCCC
VPDFSGIRVAYALDAAFHFYYQDNLELIRSTGARLIPFSPLEDREVPEADFIYIGGGFPE
CCCCCCCEEEEEHHHHHEEEECCCHHHHHHCCCEEECCCCCCCCCCCCCCEEEECCCCHH
VFAERLAKNKTMRESILTAHEKGKPVYAECGGLMYLGSSLEMEDECYEMVGVFAGVSKMT
HHHHHHHHCHHHHHHHHHHHHCCCEEHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
TRLRKFGYCIAEPLADTLIGEKGTAIRGHEFHHSVFETTEKPCMKLLKKRDGEIVKEWYG
HHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHC
GYQKGHTFASYLHIHFYQNPAILTHMFGACRK
CHHCCCCEEEEEEEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MNKILIAAASSGAGKTTITLGIMRALKQRGLVVQPFKVGPDYIDTNYHQAITGEASINLD
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCCCCH
SFLIDDEDMLAALFQKHGKVADISVIEGVMGLFDGLGTHRDNASTSFIAKCTKTPVILVV
HEEECCHHHHHHHHHHCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEE
DGKAISTSAAAIVDGFNRFDPELAIAGVIINRVASENHFSLIKGAIERYTDVPVLGYLPK
CCCCCCCHHHHHHHCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCC
NAAVALPERHLGLVPQEEMAELDAKWELLGDLIGEHVDLDRLLEISKTGADLDITSPEIN
CCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEECCCCCC
VPDFSGIRVAYALDAAFHFYYQDNLELIRSTGARLIPFSPLEDREVPEADFIYIGGGFPE
CCCCCCCEEEEEHHHHHEEEECCCHHHHHHCCCEEECCCCCCCCCCCCCCEEEECCCCHH
VFAERLAKNKTMRESILTAHEKGKPVYAECGGLMYLGSSLEMEDECYEMVGVFAGVSKMT
HHHHHHHHCHHHHHHHHHHHHCCCEEHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
TRLRKFGYCIAEPLADTLIGEKGTAIRGHEFHHSVFETTEKPCMKLLKKRDGEIVKEWYG
HHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHC
GYQKGHTFASYLHIHFYQNPAILTHMFGACRK
CHHCCCCEEEEEEEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA