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The map label for this gene is pycA [H]

Identifier: 116872468

GI number: 116872468

Start: 1064588

End: 1068028

Strand: Direct

Name: pycA [H]

Synonym: lwe1050

Alternate gene names: 116872468

Gene position: 1064588-1068028 (Clockwise)

Preceding gene: 116872467

Following gene: 116872469

Centisome position: 37.83

GC content: 38.01

Gene sequence:

>3441_bases
ATGAATCGAATTAAAAAAGTATTAGTAGCAAACCGCGGAGAGATTGCTATCCGAGTTATGCGTGCATGTACTGAACTCAA
AATCAAAACAGTGGCTATTTATTCGCAAGAAGATACTGGAAGTTTTCACCGGTATAAATCAGATGAAGCTTATCTGGTTG
GAGCAGGGAAAAAGCCTATTGATGCGTATCTAGATATCGAAAACATCATTGAAATTGCTAAAGAATCTGGTGCAGATGCG
ATTCATCCGGGATATGGTTTCTTGTCCGAAAACATTGAATTTGCTCGTCGTTGTGAGCAAGAAGGCATTATTTTCGTTGG
TCCTAAATCAAAACACCTAGATATGTTTGGCGATAAAATCAAAGCAAAAGAACAGGCTCTACTTGCTGATATTCCAGTTA
TTCCAGGTAGTAATGGACCTGTTGCTGGTATTAAAGAAGTGGAAGAATTTGGTGATAAGAACGGTTACCCATTAATGATT
AAAGCTTCCCTTGGTGGCGGCGGTCGTGGTATGCGTGTTGTTGAATCAAAAGAGCATGTTAAAGAAAGCTTTGAACGCGC
ATCCTCAGAAGCAAAAGCTGCATTTGGAAACGATGAAGTATATGTAGAAAAATGTGTAATGAATCCAAAACATATTGAAG
TACAAATTCTTGGTGATACACATGGTAACATCGTTCACTTATTTGAACGTGATTGTTCTATTCAACGTCGCCATCAAAAA
GTAGTTGAAGTAGCTCCTTGTAATGCGATTACATCCGAACTACGTAACCGTATTTGTGACGCTGCAGTAAAACTAATGAA
AAATGTTGATTACATTAATGCTGGAACAGTAGAATTTTTAGTTGAAGGCGATGATTTTTATTTTATCGAAGTAAATCCTC
GTGTTCAAGTTGAGCATACAATTACTGAAATGATTACAGGGATTGATATCGTTCAATCACAATTATTCATAGCAGATGGT
TATGCTTTACATGACCAACTAGTGGCTATTCCTAAGCAAGAAGATATCCATATTCACGGTTCTGCAATTCAAAGCCGTAT
TACTACGGAAGATCCGCTTAATAACTTTATGCCAGATACTGGTCGAGTAGATACGTATCGTTCTACAGGTGGATTTGGTG
TTCGTTTGGATGCAGGAAATGGCTTCCAAGGAACAGTAGTGACACCGTTTTATGATTCTTTACTTGTAAAATTATGTACT
TGGGGAATGACATTTGAACAAGCAACACGCAAAATGCGTCGTAACTTAATTGAATTCCGTATCCGTGGTGTGAAAACGAA
TATTCCTTTCTTATTAAATGTTGTTCGTCATCCAGATTTTGCAAGTGGTAATTATAATACAAGCTTTATCGATACGACAC
CAGAACTATTTAAATTCCCTCATATTCGCGATCGTGGTACAAAAACATTGCGTTATATTGGGAATGTAACTGTAAATGGG
TTCCCAGGAATTAAGCATCGTGATAAACCTGTGTATGCAGAACCTCGTTTGCCAAAAATTCCATATGGATCAGAAATTGC
TCCGGGAACAAAACAAATTTTGGATGCAAAAGGGCCAGAAGGTATAGTAGACTGGGTGAAAAAACAAGAAGAAGTGCTTT
TAACAGATACTACACTTCGGGATGCGCATCAATCTTTACTTGCTACTCGTGTCCGTTCCAAAGATATTTTCCAAATAGCA
GATTCGATGGCCCACTTATTACCTAACATGTTCTCCTTTGAGATGTGGGGCGGGGCGACTTTTGACGTGGCTTATCGCTT
TTTAAATGAAGATCCATGGGTGCGTCTAGAAACACTTAGAAAACAAATTCCAAATGTGATGTTCCAAATGCTACTCCGCG
GGGCTAATGCAGTCGGATATAAAAACTATCCTGATAATGTTATTCGCGAATTCGTTAAACAATCCGCACAATCTGGTGTC
GACGTCTTCCGTGTGTTTGACAGCTTAAACTGGATTAAGGGTATGGAAGTGTCAATTGATGCTGTTCGTGAAGCAGGGAA
GGTTGTAGAGGCCGCTATTTGCTACACTGGAGATATTGATGATGACACAAGAACGAAATATACGATTGACTATTATAAAG
ATATGGCAAAAGAGCTAGTTGCTCAAGGTACTCATATTTTAGGCATTAAAGATATGGCTGGTCTGTTAAAACCACAAGCT
GCTTATCGATTAATCAATGAACTAAAAGATACCGTAGATGTTCCAATCCACTTGCATACACATGATACAAGCGGCAATGG
TATTTATACCTATGCAGCAGCTGTTAGTGCGGGAGTCGACATTGTTGATGTTGCTTCCAGTGCAATGAGTGGAGCAACAA
GTCAACCAAGTATGACAGGTCTTTATTATGGGCTGGTTAATGGTAATCGCCAAACGAACCTTGATGCGCACAATTCTCAA
ATTATTAATCATTACTGGGAAGATGTTCGTCATTATTACAAAGACTTTGACAATGCGCTTAACTCACCACAAACTGAAGT
ATACATTCACGAAATGCCAGGTGGTCAATATACTAATCTGCAACAACAAGCAATTGCAGTTGGTTTAGGTGATCGTTGGG
ATGAAGTAAAAGAAATGTATACTATAGTAAACCAAATGTTTGGCGATATCGTTAAAGTAACACCTTCTTCTAAAGTTGTT
GGAGATCTGGCATTATTCATGGTCCAAAATGAACTTACTGAAGAAGATGTATACGAAAAAGGCGATACAATTGATTTCCC
TGATTCTGTTATTGAATTCTTTATGGGTGAAATTGGTCAACCATATGGCGGCTTCCCAGAAAAGTTACAAAAACTTGTAC
TCAAAGGACGTACACCACTTACGGATCGTCCAGGAGCTTTAATGGAGCCAGTTAATTTTCTTGATGTCAAAGCAGAGTTA
AAAGAAAAAATGGGTTATGAACCAACTGAAAAAGATGTTATTTCCTATATCTTGTATCCAAAAGTATTCCTAGATTATCA
GGAAATGATTAACAAATATGGTGATGTAACCGTTCTTGATACGCCGACTTTCTACAAGGGTATGCGTTTAGGTGAAACAA
TTGAAGTAGAACTTGAAAAAGGGAAAATCCTTCTAATCAAATTAAACTCTATTGGTGAACCAATTGCGGATGGAACGCGT
GTTATCTATTTTGAACTAAATGGACAACCACGTGAGATTAATATTCAAGATATGAATGTTCAATCAACTGTTATTGCACG
CCGTAAAATTGATACGACGAACCCAGAACATGTTGGAGCAACTATGACAGGTTCAGTAATTCAAGTAGTCGTGAAAAAAG
GCGATTCTGTGAAAAAAGGTGATCCATTACTAATCACAGAAGCAATGAAAATGGAAACAACTATTCAAGCACCTTTCGAC
GGAGAAGTCAGCAGTATTTATGTATCTGACGGCGATACAATCGAATCAGGTGATTTATTAATTGAAGTTAACAGAATCTA
A

Upstream 100 bases:

>100_bases
CCTAAAAAAGGGGATTATCATAATCGTATACATAGTTATTTTAACCGTTCTAGGCAATGTATAAGTATAGAACAGATCAG
TGTTGGTTAGGAGGAAAAAA

Downstream 100 bases:

>100_bases
AAACATACATGATTAACGGGTGGGAATATGATGCTAATTAAAGTGCTAAACTTTAAAAATCGAGAAGATAAACGTGAGAA
TATAGACGTTTTTCCCAGAT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1146; Mature: 1146

Protein sequence:

>1146_residues
MNRIKKVLVANRGEIAIRVMRACTELKIKTVAIYSQEDTGSFHRYKSDEAYLVGAGKKPIDAYLDIENIIEIAKESGADA
IHPGYGFLSENIEFARRCEQEGIIFVGPKSKHLDMFGDKIKAKEQALLADIPVIPGSNGPVAGIKEVEEFGDKNGYPLMI
KASLGGGGRGMRVVESKEHVKESFERASSEAKAAFGNDEVYVEKCVMNPKHIEVQILGDTHGNIVHLFERDCSIQRRHQK
VVEVAPCNAITSELRNRICDAAVKLMKNVDYINAGTVEFLVEGDDFYFIEVNPRVQVEHTITEMITGIDIVQSQLFIADG
YALHDQLVAIPKQEDIHIHGSAIQSRITTEDPLNNFMPDTGRVDTYRSTGGFGVRLDAGNGFQGTVVTPFYDSLLVKLCT
WGMTFEQATRKMRRNLIEFRIRGVKTNIPFLLNVVRHPDFASGNYNTSFIDTTPELFKFPHIRDRGTKTLRYIGNVTVNG
FPGIKHRDKPVYAEPRLPKIPYGSEIAPGTKQILDAKGPEGIVDWVKKQEEVLLTDTTLRDAHQSLLATRVRSKDIFQIA
DSMAHLLPNMFSFEMWGGATFDVAYRFLNEDPWVRLETLRKQIPNVMFQMLLRGANAVGYKNYPDNVIREFVKQSAQSGV
DVFRVFDSLNWIKGMEVSIDAVREAGKVVEAAICYTGDIDDDTRTKYTIDYYKDMAKELVAQGTHILGIKDMAGLLKPQA
AYRLINELKDTVDVPIHLHTHDTSGNGIYTYAAAVSAGVDIVDVASSAMSGATSQPSMTGLYYGLVNGNRQTNLDAHNSQ
IINHYWEDVRHYYKDFDNALNSPQTEVYIHEMPGGQYTNLQQQAIAVGLGDRWDEVKEMYTIVNQMFGDIVKVTPSSKVV
GDLALFMVQNELTEEDVYEKGDTIDFPDSVIEFFMGEIGQPYGGFPEKLQKLVLKGRTPLTDRPGALMEPVNFLDVKAEL
KEKMGYEPTEKDVISYILYPKVFLDYQEMINKYGDVTVLDTPTFYKGMRLGETIEVELEKGKILLIKLNSIGEPIADGTR
VIYFELNGQPREINIQDMNVQSTVIARRKIDTTNPEHVGATMTGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQAPFD
GEVSSIYVSDGDTIESGDLLIEVNRI

Sequences:

>Translated_1146_residues
MNRIKKVLVANRGEIAIRVMRACTELKIKTVAIYSQEDTGSFHRYKSDEAYLVGAGKKPIDAYLDIENIIEIAKESGADA
IHPGYGFLSENIEFARRCEQEGIIFVGPKSKHLDMFGDKIKAKEQALLADIPVIPGSNGPVAGIKEVEEFGDKNGYPLMI
KASLGGGGRGMRVVESKEHVKESFERASSEAKAAFGNDEVYVEKCVMNPKHIEVQILGDTHGNIVHLFERDCSIQRRHQK
VVEVAPCNAITSELRNRICDAAVKLMKNVDYINAGTVEFLVEGDDFYFIEVNPRVQVEHTITEMITGIDIVQSQLFIADG
YALHDQLVAIPKQEDIHIHGSAIQSRITTEDPLNNFMPDTGRVDTYRSTGGFGVRLDAGNGFQGTVVTPFYDSLLVKLCT
WGMTFEQATRKMRRNLIEFRIRGVKTNIPFLLNVVRHPDFASGNYNTSFIDTTPELFKFPHIRDRGTKTLRYIGNVTVNG
FPGIKHRDKPVYAEPRLPKIPYGSEIAPGTKQILDAKGPEGIVDWVKKQEEVLLTDTTLRDAHQSLLATRVRSKDIFQIA
DSMAHLLPNMFSFEMWGGATFDVAYRFLNEDPWVRLETLRKQIPNVMFQMLLRGANAVGYKNYPDNVIREFVKQSAQSGV
DVFRVFDSLNWIKGMEVSIDAVREAGKVVEAAICYTGDIDDDTRTKYTIDYYKDMAKELVAQGTHILGIKDMAGLLKPQA
AYRLINELKDTVDVPIHLHTHDTSGNGIYTYAAAVSAGVDIVDVASSAMSGATSQPSMTGLYYGLVNGNRQTNLDAHNSQ
IINHYWEDVRHYYKDFDNALNSPQTEVYIHEMPGGQYTNLQQQAIAVGLGDRWDEVKEMYTIVNQMFGDIVKVTPSSKVV
GDLALFMVQNELTEEDVYEKGDTIDFPDSVIEFFMGEIGQPYGGFPEKLQKLVLKGRTPLTDRPGALMEPVNFLDVKAEL
KEKMGYEPTEKDVISYILYPKVFLDYQEMINKYGDVTVLDTPTFYKGMRLGETIEVELEKGKILLIKLNSIGEPIADGTR
VIYFELNGQPREINIQDMNVQSTVIARRKIDTTNPEHVGATMTGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQAPFD
GEVSSIYVSDGDTIESGDLLIEVNRI
>Mature_1146_residues
MNRIKKVLVANRGEIAIRVMRACTELKIKTVAIYSQEDTGSFHRYKSDEAYLVGAGKKPIDAYLDIENIIEIAKESGADA
IHPGYGFLSENIEFARRCEQEGIIFVGPKSKHLDMFGDKIKAKEQALLADIPVIPGSNGPVAGIKEVEEFGDKNGYPLMI
KASLGGGGRGMRVVESKEHVKESFERASSEAKAAFGNDEVYVEKCVMNPKHIEVQILGDTHGNIVHLFERDCSIQRRHQK
VVEVAPCNAITSELRNRICDAAVKLMKNVDYINAGTVEFLVEGDDFYFIEVNPRVQVEHTITEMITGIDIVQSQLFIADG
YALHDQLVAIPKQEDIHIHGSAIQSRITTEDPLNNFMPDTGRVDTYRSTGGFGVRLDAGNGFQGTVVTPFYDSLLVKLCT
WGMTFEQATRKMRRNLIEFRIRGVKTNIPFLLNVVRHPDFASGNYNTSFIDTTPELFKFPHIRDRGTKTLRYIGNVTVNG
FPGIKHRDKPVYAEPRLPKIPYGSEIAPGTKQILDAKGPEGIVDWVKKQEEVLLTDTTLRDAHQSLLATRVRSKDIFQIA
DSMAHLLPNMFSFEMWGGATFDVAYRFLNEDPWVRLETLRKQIPNVMFQMLLRGANAVGYKNYPDNVIREFVKQSAQSGV
DVFRVFDSLNWIKGMEVSIDAVREAGKVVEAAICYTGDIDDDTRTKYTIDYYKDMAKELVAQGTHILGIKDMAGLLKPQA
AYRLINELKDTVDVPIHLHTHDTSGNGIYTYAAAVSAGVDIVDVASSAMSGATSQPSMTGLYYGLVNGNRQTNLDAHNSQ
IINHYWEDVRHYYKDFDNALNSPQTEVYIHEMPGGQYTNLQQQAIAVGLGDRWDEVKEMYTIVNQMFGDIVKVTPSSKVV
GDLALFMVQNELTEEDVYEKGDTIDFPDSVIEFFMGEIGQPYGGFPEKLQKLVLKGRTPLTDRPGALMEPVNFLDVKAEL
KEKMGYEPTEKDVISYILYPKVFLDYQEMINKYGDVTVLDTPTFYKGMRLGETIEVELEKGKILLIKLNSIGEPIADGTR
VIYFELNGQPREINIQDMNVQSTVIARRKIDTTNPEHVGATMTGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQAPFD
GEVSSIYVSDGDTIESGDLLIEVNRI

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1149, Percent_Identity=50.3046127067015, Blast_Score=1120, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1149, Percent_Identity=50.3046127067015, Blast_Score=1120, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1149, Percent_Identity=50.3046127067015, Blast_Score=1120, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=452, Percent_Identity=47.1238938053097, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI189095269, Length=457, Percent_Identity=44.6389496717724, Blast_Score=365, Evalue=1e-100,
Organism=Homo sapiens, GI65506442, Length=457, Percent_Identity=44.6389496717724, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI295821183, Length=457, Percent_Identity=44.6389496717724, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI134142062, Length=516, Percent_Identity=32.3643410852713, Blast_Score=238, Evalue=2e-62,
Organism=Homo sapiens, GI38679960, Length=508, Percent_Identity=32.2834645669291, Blast_Score=232, Evalue=1e-60,
Organism=Homo sapiens, GI38679971, Length=508, Percent_Identity=32.2834645669291, Blast_Score=232, Evalue=1e-60,
Organism=Homo sapiens, GI38679974, Length=508, Percent_Identity=32.2834645669291, Blast_Score=232, Evalue=2e-60,
Organism=Homo sapiens, GI38679977, Length=508, Percent_Identity=32.2834645669291, Blast_Score=232, Evalue=2e-60,
Organism=Homo sapiens, GI38679967, Length=508, Percent_Identity=32.2834645669291, Blast_Score=232, Evalue=2e-60,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=45.2115812917595, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17562816, Length=1143, Percent_Identity=49.8687664041995, Blast_Score=1117, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17567343, Length=461, Percent_Identity=43.6008676789588, Blast_Score=352, Evalue=6e-97,
Organism=Caenorhabditis elegans, GI71987519, Length=495, Percent_Identity=40.6060606060606, Blast_Score=346, Evalue=5e-95,
Organism=Caenorhabditis elegans, GI133931226, Length=493, Percent_Identity=30.6288032454361, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI71997163, Length=440, Percent_Identity=33.8636363636364, Blast_Score=214, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI71997168, Length=440, Percent_Identity=33.8636363636364, Blast_Score=214, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1152, Percent_Identity=50.3472222222222, Blast_Score=1102, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1154, Percent_Identity=49.8266897746967, Blast_Score=1099, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=459, Percent_Identity=35.9477124183007, Blast_Score=288, Evalue=5e-78,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=30.46875, Blast_Score=224, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6323863, Length=471, Percent_Identity=32.2717622080679, Blast_Score=222, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24652212, Length=1144, Percent_Identity=50.3496503496504, Blast_Score=1130, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1144, Percent_Identity=50.3496503496504, Blast_Score=1130, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1144, Percent_Identity=50.3496503496504, Blast_Score=1130, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1144, Percent_Identity=50.3496503496504, Blast_Score=1130, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1144, Percent_Identity=50.3496503496504, Blast_Score=1130, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1160, Percent_Identity=49.6551724137931, Blast_Score=1120, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1160, Percent_Identity=49.6551724137931, Blast_Score=1120, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1160, Percent_Identity=49.6551724137931, Blast_Score=1120, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1160, Percent_Identity=49.6551724137931, Blast_Score=1120, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1160, Percent_Identity=49.6551724137931, Blast_Score=1120, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=463, Percent_Identity=42.9805615550756, Blast_Score=368, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24651759, Length=425, Percent_Identity=42.3529411764706, Blast_Score=329, Evalue=7e-90,
Organism=Drosophila melanogaster, GI161076407, Length=511, Percent_Identity=30.7240704500978, Blast_Score=230, Evalue=6e-60,
Organism=Drosophila melanogaster, GI24586460, Length=511, Percent_Identity=30.7240704500978, Blast_Score=230, Evalue=6e-60,
Organism=Drosophila melanogaster, GI161076409, Length=511, Percent_Identity=30.7240704500978, Blast_Score=229, Evalue=6e-60,
Organism=Drosophila melanogaster, GI24586458, Length=511, Percent_Identity=30.7240704500978, Blast_Score=229, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128189; Mature: 128189

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIKKVLVANRGEIAIRVMRACTELKIKTVAIYSQEDTGSFHRYKSDEAYLVGAGKKPI
CCHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEEEECCCCCCCCEECCCCEEEEECCCCCC
DAYLDIENIIEIAKESGADAIHPGYGFLSENIEFARRCEQEGIIFVGPKSKHLDMFGDKI
HHHCCHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHCCCCEEEECCCCCCHHHHHHHH
KAKEQALLADIPVIPGSNGPVAGIKEVEEFGDKNGYPLMIKASLGGGGRGMRVVESKEHV
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECHHHHH
KESFERASSEAKAAFGNDEVYVEKCVMNPKHIEVQILGDTHGNIVHLFERDCSIQRRHQK
HHHHHHHCHHHHHCCCCCCEEEHHHCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVEVAPCNAITSELRNRICDAAVKLMKNVDYINAGTVEFLVEGDDFYFIEVNPRVQVEHT
HHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEECCCEEEHHH
ITEMITGIDIVQSQLFIADGYALHDQLVAIPKQEDIHIHGSAIQSRITTEDPLNNFMPDT
HHHHHHHHHHHHHHEEEECCEEECCCEEECCCCCCEEEEHHHHHHCCCCCCCHHHCCCCC
GRVDTYRSTGGFGVRLDAGNGFQGTVVTPFYDSLLVKLCTWGMTFEQATRKMRRNLIEFR
CCCCCEECCCCEEEEEECCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IRGVKTNIPFLLNVVRHPDFASGNYNTSFIDTTPELFKFPHIRDRGTKTLRYIGNVTVNG
HCCCCCCCHHHHHHHCCCCCCCCCCCCEEECCCHHHHCCCCCCCCCCCEEEEECCEEECC
FPGIKHRDKPVYAEPRLPKIPYGSEIAPGTKQILDAKGPEGIVDWVKKQEEVLLTDTTLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCEEEECCHHH
DAHQSLLATRVRSKDIFQIADSMAHLLPNMFSFEMWGGATFDVAYRFLNEDPWVRLETLR
HHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHCCCCCCHHHHHH
KQIPNVMFQMLLRGANAVGYKNYPDNVIREFVKQSAQSGVDVFRVFDSLNWIKGMEVSID
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEHH
AVREAGKVVEAAICYTGDIDDDTRTKYTIDYYKDMAKELVAQGTHILGIKDMAGLLKPQA
HHHHHHHHEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHCHHH
AYRLINELKDTVDVPIHLHTHDTSGNGIYTYAAAVSAGVDIVDVASSAMSGATSQPSMTG
HHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCCCCCCE
LYYGLVNGNRQTNLDAHNSQIINHYWEDVRHYYKDFDNALNSPQTEVYIHEMPGGQYTNL
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCH
QQQAIAVGLGDRWDEVKEMYTIVNQMFGDIVKVTPSSKVVGDLALFMVQNELTEEDVYEK
HHHHHEECCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHC
GDTIDFPDSVIEFFMGEIGQPYGGFPEKLQKLVLKGRTPLTDRPGALMEPVNFLDVKAEL
CCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHHHH
KEKMGYEPTEKDVISYILYPKVFLDYQEMINKYGDVTVLDTPTFYKGMRLGETIEVELEK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCEEEEEEEC
GKILLIKLNSIGEPIADGTRVIYFELNGQPREINIQDMNVQSTVIARRKIDTTNPEHVGA
CCEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCC
TMTGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQAPFDGEVSSIYVSDGDTIESGDLL
CHHHHHHHHHHHCCCCCCCCCCEEEEECHHHCEEEECCCCCCCEEEEECCCCEEECCCEE
IEVNRI
EEEECC
>Mature Secondary Structure
MNRIKKVLVANRGEIAIRVMRACTELKIKTVAIYSQEDTGSFHRYKSDEAYLVGAGKKPI
CCHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEEEECCCCCCCCEECCCCEEEEECCCCCC
DAYLDIENIIEIAKESGADAIHPGYGFLSENIEFARRCEQEGIIFVGPKSKHLDMFGDKI
HHHCCHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHCCCCEEEECCCCCCHHHHHHHH
KAKEQALLADIPVIPGSNGPVAGIKEVEEFGDKNGYPLMIKASLGGGGRGMRVVESKEHV
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECHHHHH
KESFERASSEAKAAFGNDEVYVEKCVMNPKHIEVQILGDTHGNIVHLFERDCSIQRRHQK
HHHHHHHCHHHHHCCCCCCEEEHHHCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVEVAPCNAITSELRNRICDAAVKLMKNVDYINAGTVEFLVEGDDFYFIEVNPRVQVEHT
HHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEECCCEEEHHH
ITEMITGIDIVQSQLFIADGYALHDQLVAIPKQEDIHIHGSAIQSRITTEDPLNNFMPDT
HHHHHHHHHHHHHHEEEECCEEECCCEEECCCCCCEEEEHHHHHHCCCCCCCHHHCCCCC
GRVDTYRSTGGFGVRLDAGNGFQGTVVTPFYDSLLVKLCTWGMTFEQATRKMRRNLIEFR
CCCCCEECCCCEEEEEECCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IRGVKTNIPFLLNVVRHPDFASGNYNTSFIDTTPELFKFPHIRDRGTKTLRYIGNVTVNG
HCCCCCCCHHHHHHHCCCCCCCCCCCCEEECCCHHHHCCCCCCCCCCCEEEEECCEEECC
FPGIKHRDKPVYAEPRLPKIPYGSEIAPGTKQILDAKGPEGIVDWVKKQEEVLLTDTTLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCEEEECCHHH
DAHQSLLATRVRSKDIFQIADSMAHLLPNMFSFEMWGGATFDVAYRFLNEDPWVRLETLR
HHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHCCCCCCHHHHHH
KQIPNVMFQMLLRGANAVGYKNYPDNVIREFVKQSAQSGVDVFRVFDSLNWIKGMEVSID
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEHH
AVREAGKVVEAAICYTGDIDDDTRTKYTIDYYKDMAKELVAQGTHILGIKDMAGLLKPQA
HHHHHHHHEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHCHHH
AYRLINELKDTVDVPIHLHTHDTSGNGIYTYAAAVSAGVDIVDVASSAMSGATSQPSMTG
HHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCCCCCCE
LYYGLVNGNRQTNLDAHNSQIINHYWEDVRHYYKDFDNALNSPQTEVYIHEMPGGQYTNL
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCH
QQQAIAVGLGDRWDEVKEMYTIVNQMFGDIVKVTPSSKVVGDLALFMVQNELTEEDVYEK
HHHHHEECCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHC
GDTIDFPDSVIEFFMGEIGQPYGGFPEKLQKLVLKGRTPLTDRPGALMEPVNFLDVKAEL
CCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHHHH
KEKMGYEPTEKDVISYILYPKVFLDYQEMINKYGDVTVLDTPTFYKGMRLGETIEVELEK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCEEEEEEEC
GKILLIKLNSIGEPIADGTRVIYFELNGQPREINIQDMNVQSTVIARRKIDTTNPEHVGA
CCEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCC
TMTGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQAPFDGEVSSIYVSDGDTIESGDLL
CHHHHHHHHHHHCCCCCCCCCCEEEEECHHHCEEEECCCCCCCEEEEECCCCEEECCCEE
IEVNRI
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]